Gene 81801.m00059 (T.vaginalis)

81801.m00059

Species: T.vaginalis
Alias: TvagK0148, 81801.m00059
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81801.m00059.AA Protein None 180 None Fasta, JSON
81801.m00059.kin_dom Protein Kinase Domain None 117 None Fasta, JSON

Protein domain

Protein domains of 81801.m00059.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81801.m00059.AA CAMKL 26-132 30 2.8e-31 96.96 In-house 143-264 (297) Show / Hide 
Range on Protein: 26-132
Range on HMM: 143-264/297
Sequence Identity: 30% (38 aa)

LHDNNVAHHDIKPSNFLVDKYG--RIKCCDFGLSSVYD-C---DDVQSSVHKGTLLFMSPEMLSM--TPFNPMKSDIWALGVTLFFMATKTYPFIASDA-
.|.....| |||| | |.|. |   || .|||.|  |. |   ..   . . |.. .|.||...   .|..  | |||..||.|..| . ..|| . .  
CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN

-------RLLLKVMNATSSFPIF
       .|..|.|     .||.
KQGKDNIYLYWKIMCG-YYPPIW
Kinase 81801.m00059.AA CAMK 5-125 19 7.7e-30 92.77 In-house 163-362 (425) Show / Hide 
Range on Protein: 5-125
Range on HMM: 163-362/425
Sequence Identity: 19% (39 aa)

EE-----------INEEVMCKYMHDVVLCIKSLHDNNVAHHDIKPSNFLVDKY-----------------GRIKCCDFGLSSVYDC--------------
||           ..|.  ..|.. ..  .. .|..|..| |.|| | |.|.                  . || .|||.. ..|               
EEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE

---------DDVQSSVHKGTLLFMS-PEMLSM-------------TPFNPMKSDIWALGVTLFFMATKTYPFIAS--------------DARLLLKVMNA
         ..   .   ||. .|. ||.|.               |  . |.|.|..|| |..| . ..|| ..              | .|. |.|..
MHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKG
Kinase 81801.m00059.AA Ciliate-E2-Unclassified 1-111 29 3.8e-26 87.7 In-house 129-270 (352) Show / Hide 
Range on Protein: 1-111
Range on HMM: 129-270/352
Sequence Identity: 29% (42 aa)

MKSEEEINEEVMC-----KYMHDVVLCIKSLHDNN-VAHHDIKPSNFLVDKYG---RIKCCDFGLSSVYDCD--------------DVQSSVHK-GTLLF
||. ... |. ..     .|.  .......|| .| . | ||||.| |.|. |   .|| .|||.|. |. .              . | . .. ||. .
MKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNY

M----SPEMLSMTPFNPM---KSDIWALGVTLFFMATKTYPF
|    .||.|     . .   |.|||.||| |..| . .|||
MPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPF
Kinase 81801.m00059.AA CAMKK 14-115 25 6.2e-26 78.93 In-house 180-330 (396) Show / Hide 
Range on Protein: 14-115
Range on HMM: 180-330/396
Sequence Identity: 25% (39 aa)

KYMHDVVLCIKSLH-DNN-------------------VAHHDIKPSNFLVDKYG---RIKCCDFGLSSVYDCDDVQSSV-----------HKGTLLFMSP
||. |... .. || ...                   . | ||||.| |.|. |   ..| .||| |   . .| ..|              ||  || |
KYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAP

EMLSM-TP--------------FNPMKSDIWALGVTLFFMATKTYPFIASD
|..|                  ..  . |||||||||. . ... ||.. .
ELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNN
Kinase 81801.m00059.AA Ciliate-E2 2-130 22 1.1e-24 81.64 In-house 131-308 (365) Show / Hide 
Range on Protein: 2-130
Range on HMM: 131-308/365
Sequence Identity: 22% (43 aa)

KSEEEIN------EEVMCKYMHDVVL---------------CIKSLHDNN-VAHHDIKPSNFLVDKYGRIKCCDFGLSS-VYDCDDVQS--SVHK-----
|. .||.      |. ....|  ..                ....|| .| . | ||||.| |.     || .|||||  . |. . ..  . .|     
KRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFK

-----------------------GTLLFMSPEMLSMTPF--------NPMKSDIWALGVTLFFMATKTYPFIASDARLLLKVMNATSSFP
                       ||. .|.||.|.. .            |.|||.|||.|..| .. .||       . . ..   .||
NDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------QQQIKQCKIDFP
Kinase 81801.m00059.AA ULK 3-117 26 1.7e-23 78.91 In-house 118-261 (329) Show / Hide 
Range on Protein: 3-117
Range on HMM: 118-261/329
Sequence Identity: 26% (38 aa)

SEEE-----INEEVMCKYMHDVVLCIKSLHDNNVAHHDIKPSNFLVDKY------------GRIKCCDFGLSSVYDCD-----DVQSSV----HKGTLLF
.|..     ..|.   ..... .   | ||..|. | ||||.| |...             |..| .|||.. . |.|     . .. |     .|| |.
PEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLY

MSPEMLS----MTPFNPMKSDIWALGVTLFFMATKTYPFIASDAR
|.|. |.      |..  |.||| ||. .. | .  .|| |. ..
MAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FN
Kinase 81801.m00059.AA MARK 26-111 39 5.2e-23 72.21 In-house 120-206 (262) Show / Hide 
Range on Protein: 26-111
Range on HMM: 120-206/262
Sequence Identity: 39% (35 aa)

LHDNNVAHHDIKPSNFLVDKYG--RIKCCDFGLSSVYDCDDVQSSVHKGTLLFMSPEMLSMTPFNPMKSDIWALGVTLFFMATKTYPF
.|..|..| |||| | |.|. |   || .|||. |.    .   . . ||. .|.||...  | .  | |||.||| |.|| . ..||
CHSKNIVHRDIKPENILIDENGNHNIKIIDFGF-SICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPF
Kinase 81801.m00059.AA ULK 2-117 25 5.6e-22 74.81 In-house 114-257 (324) Show / Hide 
Range on Protein: 2-117
Range on HMM: 114-257/324
Sequence Identity: 25% (37 aa)

KSEEE-----INEEVMCKYMHDVVLCIKSLHDNNVAHHDIKPSNFLVDKY------------GRIKCCDFGLSSVYDCDDVQSSVH---------KGTLL
..| .     ..|.   ..... .   | ||..|. | ||||.| |. .             |..| .|||.. . |... .  .          ||| |
LPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPL

FMSPEMLS----MTPFNPMKSDIWALGVTLFFMATKTYPFIASDAR
.|.|. |.      |..  |.||| ||. .. | .  ||| .. ..
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FN
Kinase 81801.m00059.AA CAMKK-Unclassified 14-115 22 1.2e-21 66.98 In-house 182-337 (392) Show / Hide 
Range on Protein: 14-115
Range on HMM: 182-337/392
Sequence Identity: 22% (35 aa)

KYMHDVVLCIKSLHDNN---------------------VAHHDIKPSNFLVDKYGR-----IKCCDFGLSSVYDCDDVQ-SSVHKGTLLFMSPEMLSMTP
||. .. . ....|..|                     . | |||| | | |. ..     .| .|||.|     ..    .   ||. ||.|| .|   
KYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKEN

FNPMKSD---------------------------IWALGVTLFFMATKTYPFIASD
|.   .|                           ||.||||.. |.... || ...
FKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKN
Kinase 81801.m00059.AA Pkinase 7-111 28 5.2e-21 75.38 Pfam 103-212 (293) Show / Hide 
Range on Protein: 7-111
Range on HMM: 103-212/293
Sequence Identity: 28% (32 aa)

I--NEEVMCKYMHDVVLCIKSLHDNNVAHHDIKPSNFLVDKYGRI----KCCDFGLSSVY-DCDDVQSSVHKGTLLFMSPEMLSMTPFNPMKSDIWALGV
.   |.. ..||  ..  .. .|.... | |.||.|.|.|. | |    | |||||. ..    ..  ..  ||. .|.|| .   .  . |.|.|..|.
FYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGC

TLFFMATKTYPF
.|. |...  ||
ILYEMLCGRPPF
Kinase 81801.m00059.AA STE 7-111 24 1.2e-19 66.1 In-house 148-268 (359) Show / Hide 
Range on Protein: 7-111
Range on HMM: 148-268/359
Sequence Identity: 24% (31 aa)

INEEVMCKYMHDVVLC-IKSLHDNNVAHHDIKPSNFLVDKYGRIKCCDFGLSS--VYDCD--------------DVQSSVHKGTLLFMSPEMLSMTPFNP
..|.. ... ....    . ||.... | ||||.| |.     .| ||||...  . ...              . ..    ||  .|.||...    . 
FPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-

M------KSDIWALGVTLFFMATKTYPF
       |.||| || |.  |||  .|.
RDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase 81801.m00059.AA S_TKc 1-152 15 3.5e-09 -42.34 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-152
Range on HMM: 19-231/231
Sequence Identity: 15% (36 aa)

MKSE-----------------------------------------------EE--------------------INEEVMCKYMHDVVLCIKSLHDNNVAH
 . .                                               .                     ..| . ..||. ... .. .|.... |
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIH

HDIKPSNFLVDKYGRIKCCDFGLSSVYDCDDVQSSVHKGTLLFMSPEMLSMTPFNPMKSDIWALGVTLFFMATKTYPFIASDARLLLKVMNATSSFPIFA
 |.||.| |.|.  .|| |||||. ..       .   ||. .|.||.|   .... |.|.|..|..|. |..   ||   .  ...|..      | . 
RDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----SPEAK

-------VRNAQLRREQDKFAT-------RHFF
       ... . |    .  .         .|
DFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF