Gene 83007.m00211 (T.vaginalis)
83007.m00211
Species: T.vaginalis
Alias: 83007.m00211, TvagK0450
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 83007.m00211.AA | Protein | None | 384 | None | Fasta, JSON |
| 83007.m00211.kin_dom | Protein Kinase Domain | None | 133 | None | Fasta, JSON |
Protein domains of 83007.m00211.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 83007.m00211.AA | CK1 | 1-159 | 56 | 5e-90 | 305.41 | In-house | 109-271 (271) | Show / Hide |
Range on Protein: 1-159 Range on HMM: 109-271/271 Sequence Identity: 56% (92 aa) MLATQMISCVEYVHKHKYIHRDIKPDNFAMGV-GENSNKVYIIDFGLSKKFVD-SNNRHIRNCSGKSLTGTARYASINALEGKEQSRRDDMESLFYVWIY |.| |||. .||||.. .|||||||||| ||. | ....||||||||.|...| ....|| .|.|||||||||||. |.||||||||||| || .| MIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMESLGYVLMY LLRGKLPWMGLPAKGNK-KYEAILMKKKSTEPEDLCSG-LNSFFINYYTSVRSLKFEEEPNYA .|||.|||.|| |. .| ||| |..|| || .|.||.| . . |..| . .|.|.|||.|.|. FLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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| Kinase | 83007.m00211.AA | CK1-Unclassified | 1-133 | 58 | 1.2e-88 | 261.77 | In-house | 108-244 (244) | Show / Hide |
Range on Protein: 1-133 Range on HMM: 108-244/244 Sequence Identity: 58% (80 aa) MLATQMISCVEYVHKHKYIHRDIKPDNFAMG-VGENSNKVYIIDFGLSKKFV--DSNNRHIRNCSGKSLTGTARYASINALEGKEQSRRDDMESLFYVWI |.| |||. .||.|.. .|||||||||| || | |...||||||||||... |....|| .|.|||||||||||| |.|||||||.||| || | MIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLESLGYVLI YLLRGKLPWMGLPAKGNK-KYEAILMKKKSTEPEDLC |.|.|.|||... |. | ||| |. .| || .| || YFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC |
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| Kinase | 83007.m00211.AA | CK1 | 1-161 | 34 | 3.3e-70 | 239.56 | In-house | 136-339 (339) | Show / Hide |
Range on Protein: 1-161 Range on HMM: 136-339/339 Sequence Identity: 34% (72 aa) MLATQMISCVEYVHKHKYIHRDIKPDNFAMGV-------------GENSNKVYIIDFGLSK-KFVDSNN------------RHIRNCS---GKSLTG-TA |.| ||.. .||.| . .||||||||||.||. ......||.||||... |..|... .|.. . |...| || MIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTA RYASINALEGKEQSRRDDMESLFYVWIYLLRGK--LPWMGLPA--------KGNKKYEAILMKKKSTEPEDLCSG-----LNSFFINYYTSVRSLKFEEE ||.|||. .||||.||||..|.||. |..|.|. |||... . . .||| | ||.|| .. || . . . | ... .||||.... RYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDR PNYAMY |.|.| PDYEMI |
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| Kinase | 83007.m00211.AA | CK1-D | 1-161 | 54 | 5.5e-69 | 235.51 | In-house | 99-261 (261) | Show / Hide |
Range on Protein: 1-161 Range on HMM: 99-261/261 Sequence Identity: 54% (89 aa) MLATQMISCVEYVHKHKYIHRDIKPDNFAMGVGENSNKVYIIDFGLSKKFVDSN-NRHIRNCSGKSLTGTARYASINALEGKEQSRRDDMESLFYVWIYL ||| |||. .||.| ...|||||||||| ||.| | ||||||||.|.. |.. .|| |.||||||||||| | |||||||.||| || .| MLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYF LRGKLPWMGLPAKGNK-KYEAILMKKKSTEPEDLCSGLNSFFINYYTSVRSLKFEEEPNYAMY || ||| || | . ||| | || ||. ..||.|. | | .| .|.|||.. |.|. NRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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| Kinase | 83007.m00211.AA | CK1-A | 1-161 | 57 | 4.5e-67 | 229.16 | In-house | 99-261 (261) | Show / Hide |
Range on Protein: 1-161 Range on HMM: 99-261/261 Sequence Identity: 57% (94 aa) MLATQMISCVEYVHKHKYIHRDIKPDNFAMGVGENSNKVYIIDFGLSKKFVDSNNR-HIRNCSGKSLTGTARYASINALEGKEQSRRDDMESLFYVWIYL ||| |||. .||||.. .|||||||||| ||.| ||...|||||.||. ||. | || | |||||||||||| | ||||||||||. || .| MLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYF LRGKLPWMGLPAKGNK-KYEAILMKKKSTEPEDLCSGLNSFFINYYTSVRSLKFEEEPNYAMY |||||| |. |. | ||| |. || || | || | . | | . .|.|.|||.|.| NRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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| Kinase | 83007.m00211.AA | CK1-G | 1-161 | 47 | 6.3e-63 | 212.09 | In-house | 100-266 (266) | Show / Hide |
Range on Protein: 1-161 Range on HMM: 100-266/266 Sequence Identity: 47% (80 aa) MLATQMISCVEYVHKHKYIHRDIKPDNFAMG--VGENSNKVYIIDFGLSKKFVDSN-NRHIRNCSGKSLTGTARYASINALEGKEQSRRDDMESLFYVWI |.|.|||. .||||.| | ||.||||| | .. ....|||||. |...| . ..|| ||||||||| ||| |.|||||||||.| . . MVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFM YLLRGKLPWMGLPAKGNK-KYEAILMKKKSTEPEDLCSG--LNSFFINYYTSVRSLKFEEEPNYAMY | |||.||| || | || .|. | ..|..| .|||| . . | | ||.|.|.|.| | YFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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| Kinase | 83007.m00211.AA | TTBKL | 5-165 | 29 | 1.4e-35 | 117.67 | In-house | 110-288 (288) | Show / Hide |
Range on Protein: 5-165 Range on HMM: 110-288/288 Sequence Identity: 29% (54 aa) QMISCVEYVHKHKYIHRDIKPDNFAMGVGEN----SNKVYIIDFGLSKKFVDSNN-------------RHIRN-CSGKSLTGTARYASINALEGKEQSRR | . .. ..| . .||||.|| |...|. .. . ||.||||.......... | || .. || ||.|.|. ..|||.| QCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRH DDMESLFYVWIYLLRGKLPWMGLPAKGNKKYEAILMKKKSTEPEDLCSG------LNSFFINYYTSVRSLKFEEEPNYAMYRKMI ||. |..|. |.|. | ||| .. | . | .||.. |||... . | | .. .|||.. ..|.| | .. . DDLWSWMYMIIELHCG-LPWTNMEDK-----MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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| Kinase | 83007.m00211.AA | Worm6 | 2-116 | 32 | 1.6e-34 | 121.03 | In-house | 109-231 (279) | Show / Hide |
Range on Protein: 2-116 Range on HMM: 109-231/279 Sequence Identity: 32% (41 aa) LATQMISCVEYVHKHKYIHRDIKPDNFAMGV-----GENSNKVYIIDFGLSK--KFVDSNN--RHIR-NCSGKSLTGTARYASINALEGKEQSRRDDMES .| |.. .| .|.. .||||.|| ||. |. ... ..|..|||... |. . .| |. | . | || |||.... |.||.|.||.|| IAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACG--FRGTVRYAPLACHKGQEQCRKDDCES LFYVWIYLLRGKLPWMGLPAKGNKK ||. . ...|.|||... .. ... WFYMMVEMIVGCLPWRHMKDHDHVE |
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| Kinase | 83007.m00211.AA | TTBK | 2-161 | 33 | 3.8e-32 | 110.92 | In-house | 102-257 (257) | Show / Hide |
Range on Protein: 2-161 Range on HMM: 102-257/257 Sequence Identity: 33% (54 aa) LATQMISCVEYVHKHKYIHRDIKPDNFAMG-VGENSNKVYIIDFGLSKKFVDSNN--RHIRNCSGKSLTGTARYASINALEGKEQSRRDDMESLFYVWIY | |.. .| .| . |||||| ||||| . .. .|.|..|||| ... . | |. | ||.||||||| .| |.||. ||||. . LGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAG--FRGTVRYASINAHRNREMGRHDDLWSLFYMLVE LLRGKLPWMGLPAKGNKKYEAILMKKKSTEPEDLCSGLNSFFINYYTSVRSLKFEEEPNYAMY . | ||| . | . . . |. . .| . . | . ..||..|. |.|.. FVQGQLPWRKI-----KDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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| Kinase | 83007.m00211.AA | Dual | 3-100 | 35 | 1.1e-24 | 79.85 | In-house | 119-213 (282) | Show / Hide |
Range on Protein: 3-100 Range on HMM: 119-213/282 Sequence Identity: 35% (35 aa) ATQMISCVEYVHKHKYIHRDIKPDNFAMGVGENSNKVYIIDFGLSKKFVD-SNNRHIRNCSGKSLTGTARYASINALEGKEQSRRDDMESLFYVWIYLL | ||. . . | |.||.||| ||. |.|. .|| ||.. .|..| .| | .. |..|||.. . |.| | ||.|. |||.. AIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLEC----WIYMV |
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| Kinase | 83007.m00211.AA | Pkinase | 1-152 | 22 | 7.9e-15 | 53.51 | Pfam | 112-258 (293) | Show / Hide |
Range on Protein: 1-152 Range on HMM: 112-258/293 Sequence Identity: 22% (36 aa) MLATQMISCVEYVHKHKYIHRDIKPDNFAMG-VGENSNKVYIIDFGLSKKFVDSNNRHIRNCSGKSLTGTARYASINALE-GKEQSRRDDMESLFYVWIY . ..|... .|| |... ||||.||.|. . |... .| |.||||.|.| . .| ....|| .|.. . |.. ... || |. . .. FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYE LLRGKLPWMGL----PAKGNKKYEAILMKKKSTEPEDLCSGLNSFFINYYTSVRSLKF .| |..|. | .. ..... |.... . . . .||. ..| ... . . ... MLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWT |
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