Gene 94035.m00029 (T.vaginalis)

94035.m00029

Species: T.vaginalis
Alias: TvagK0333, 94035.m00029
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94035.m00029.AA Protein None 752 None Fasta, JSON
94035.m00029.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 94035.m00029.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94035.m00029.AA TKL 209-453 28 8.8e-87 294.61 In-house 1-364 (364) Show / Hide 
Range on Protein: 209-453
Range on HMM: 1-364/364
Sequence Identity: 28% (104 aa)

IGEGISGRVVKGKIKS--------TGMVVAIKILHLRQLSGADM-------------------------ERFRNEIFAMSTLTHPSLLPFCGYTQEAP--
||.| .| | ||| .         || .||.|... .. .  ..                         .....||  || | || ...| || .. |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCLATKFMENGSLFNILSTNPSFLSPTDRTLIAYDVACGMEFLHS--------RGVIHRDLKSLNILIDENKR--------------G
            .|. . ....|||...|        .  |  .|.|.|.||..|||        ...||||||| |||.||| .               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KISDFGFVRMKS---SVPMTG------------------LVGTSHWMAPEILLSSPN---------------YDEKIDIYSYGIVLWELLTSEKPYA--N
||.|||. |..|   .  .|.                   .||  |||||.|  ..|               |.||.|.||.||||||.|| ..||.  .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

ENPATLP-------LKVIEHNLRPTIP------------EGTPIKMKTLIERCWSLSPEQRPSFHDIINYF
..|  .         .|....|||.||            . .|  || |...||.  ||.|||| .|. ..
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 94035.m00029.AA MLK 203-453 32 1.3e-76 260.84 In-house 1-291 (291) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-291/291
Sequence Identity: 32% (94 aa)

LEFGKQIGEGISGRVVKGKIKSTG---MVVAIKILHLRQ----LSGADMERFRNEIFAMSTLTHPS----LLPFCGYTQEA-P-YCLATKFMENGSLFNI
..| . ||.| .| | ||. . .     .||.|. . |      ...  . |. |.   . | ||       .| |  ..  . .|. . ..|.|||.|.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LSTNPS-------------FLSPTDRTLIAYDVACGMEFLHSRG---VIHRDLKSLNILIDE------NKRGKISDFGFVRMKSSV-P-MTGLVGTSHWM
| ...|               ..     .|...| ||..|||     .||||||| ||||||      ..  ||.||| .|....    |..  ||  ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEIL--LSSPNYDEKIDIYSYGIVLWELLTSEKPYA-NENPATLPLKVIEHNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIINYF
|||..  . .  |.|| |..|.|.||||.|| | ||.   .|..   .|....|||.|| . |  .| |...||.  |..||||  |. ..
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 94035.m00029.AA TKL-Unique 205-453 34 7.1e-68 231.8 In-house 1-290 (290) Show / Hide 
Range on Protein: 205-453
Range on HMM: 1-290/290
Sequence Identity: 34% (100 aa)

FGKQIGEGISGRVVKGKIKSTGMVVAIKILHLRQLSGADMER-FRNEIFAMSTLT-HPSLLPFCGYTQ----EAP-YCLATKFMENGSLFNILS------
|.. |||| .|.| ||| ...   ||||..|.  .|  .|.. |.||.  |..|  || .. . ||.      .| .|. . ... ||| . |.      
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---TNPSFLSPTDRTLIAYDVACGMEFLHSRG--VIHRDLKSLNILIDEN-----KRGKISDFGFVRMKSSV---PMT--------GLVGTSHWMAPEIL
    | . |..  |  .| |.| ||..||...  .|||||||.|.|.|.|      . ||.|||... .|.    . .        . .|.  |||||.|
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LSS-PNYDEKIDIYSYGIVLWELLTSEK------PYANENPATLPLKVIE--HNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIINYF
 ..   |.||.|.||.||||||..|..       || . ..  .  .| .   |.||.||.  |   . ||..||   |.||||| .||.. 
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 94035.m00029.AA Pkinase 203-453 27 5.4e-66 230.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKILHLRQLSGADMERFRN--EIFAMSTLTHPSLLPFCGYTQ-EAPYCLATKFMENG----SLFNILS--TN
...|..||.| .|.| |.. |.|| .||.||. .|  .    .. |.  ||  |  | ||  . . .. . .  ... . ..|.|    .|| ..|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PSF-LSPTDRTLIAYDVACGMEFLHSRGVIHRDLKSLNILIDENKRG----KISDFGFVR---MKSSVPMTGLVGTSHWMAPEILLSSPNYDEKIDIYSY
 .| .|. .   ..| ...|.|..||.|.||||||. |||||.|       ||.|||. .     ... ||...||...||||...... |. |.|..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVLWELLTSEKPYANE---NPATLPLKVIEHNLRPTIPEGTP-----------------------IKMKTLIERCWSLSPEQRPSFHDIINY--F
|..|.|.|. . |. ..    .   ....|. ...| ...  |                         .| .|..|. . |..||....| .   |
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94035.m00029.AA Dicty4 203-455 33 2e-65 217.19 In-house 1-277 (277) Show / Hide 
Range on Protein: 203-455
Range on HMM: 1-277/277
Sequence Identity: 33% (95 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKIL--HLRQLSGADMERFRNEIFAMSTLTHPSLLPFCGYTQ---EAP--YCLATKFMENGSLFNILST---
. ... ||.|  | | ||. .  |  ||.|.|  |   .. . .. ||.|.  |. . || .. | |.      .|   |  | .|  |.|...|     
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

--NPSFLSP-TDRTL---IAYDVACGMEFLHSRG--VIHRDLKSLNILIDENKRGKISDFGFVR----MKSSVP-MTGLVGTSHWMAPEILLSSPNYDEK
   .|  .. ....    .| |.| ||  ||..   .||||||| |.|.|.|.| |..|||. .     ..    ... .||  |||||.. . | |.||
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEK

IDIYSYGIVLWELLTSEKPYA--NENPATLPLKVIEHNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIINY--FTD
 | ||.||||||.|| . ||.    ..  .   | .. ||| ||  .| . |.||..||. .|..||||  ||..     
ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 94035.m00029.AA Dicty5 203-457 39 1.5e-60 207.14 In-house 1-260 (260) Show / Hide 
Range on Protein: 203-457
Range on HMM: 1-260/260
Sequence Identity: 39% (103 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKILHLRQLSGADMERFRNEIFAMSTLT--HPSLLPFCG-YTQEAPY-CLATKFMENGSLFNILSTNPS---
  |.. |  | |||| .|  |  || |||| .      . |.. |  |.  ||     || .  . |  ...  |    | .  |||||| |        
VSFHDWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTG

-FLSPTDRTLIAYDVACGMEFLHSRGVIHRDLKSLNILIDENKRGKISDFGFVR-MKSSVPMTGLVGTSHWMAPEILLSSPNYDEKIDIYSYGIVLWELL
  ..   .  .| |.| .|..||| ..|||||||.|.|| ||   || |||  |       ||  |||. |||.|.  . | |..| |.||.||||||..
QPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQP-YHQKCDVYSFGIVLWEMF

TSEKPYANENPATLPLKVIEHNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIINYFTDPE
|   || | |    |. |     |||||   |     ||. ||   | .||||  |. ||    
TRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 94035.m00029.AA Pkinase_Tyr 203-453 30 1.7e-58 198.75 Pfam 1-270 (270) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-270/270
Sequence Identity: 30% (82 aa)

LEFGKQIGEGISGRVVKGKIK----STGMVVAIKILHLRQLSGAD--MERFRNEIFAMSTL-THPSLLPFCGYTQ--EAP--YCLATKFMENGSLFNILS
..|||..|||  |.|.||. |    .|.. ||.|.|   . .  .  .| | .|.  |..|  || .. . |     . |  ... . .|..|.| . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

TN---PSFLSPTDRTLIAYDVACGMEFLHSRGVIHRDLKSLNILIDENKRGKISDFGFVRMK----SS-VPMTGLVGTSHWMAPEILLSSPNYDEKIDIY
..   .  |.. |   .....|.|||.|.|.. |||||   |.|..||.  ||.|||  |         .  .|      ||||| .  .  . .| |..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

SYGIVLWELLT-SEKP-YANENPATLPLKVIEHNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIINYF
|.|...||..|  |.| |..  .. .  .. |.. |  .||..| .. .|. .||   ||.||.| .|.. .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 94035.m00029.AA LRRK 203-455 28 4.4e-58 199.28 In-house 1-351 (351) Show / Hide 
Range on Protein: 203-455
Range on HMM: 1-351/351
Sequence Identity: 28% (99 aa)

LEFGKQIGEGISG-RVVKGKIKS--------------------------TGMVVAIKILHLR----------------------------QLSGADMER-
|....|||.| .| .| ..| ..                           .  ||||....                              . ..|. | 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

---FRNEIFAMSTLTHPSLLPFCGYTQEAPYCLATKFMENGSLFNILSTNPS--F------LSPTDRTLIAYDVACGMEFLHSRG--VIHRDLKSLNILI
   ||.|.. ||.|.||....  |.. . |.|... .. .|.|   |. . .  |      .|.. .  ||...| |||.|||.   .||||||| |||.
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DENKRG------------KISDFGFVRMKSSVPMT---GLVGTSHWMAPEILLSS--PNYDEKIDIYSYGIVLWELLTSE-KPYANEN-------PATLP
 . . .            ||.|||  || ....|.   |.||.  ||||||.      .|.||.|.||.|..|||||| .  |. . .         .. 
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

LKVIEHNLRPTIPEG-TPI-----KMKTLIERCWSLSPEQRPSFHDIINYFTD
.|.||  ||||||.   |       ...||. ||.  |..||.| .|.    .
DKIIE-GLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 94035.m00029.AA S_TKc 203-453 27 4.3e-57 196.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKILHLRQLSGADMERFRNEIFAMSTLTHPSLLPFCGYTQEAPYCLATKFMEN--GSLFNILSTNPSF----
 |....||.|  |.| |.. |.|| .|||||..         |..|.||  ..   || .  . .. |.  ... . ....  |.|| ..  ...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSPTDRTLIAYDVACGMEFLHSRGVIHRDLKSLNILIDENKRGKISDFGFVRMKSSVPMTGLVGTSHWMAPEILLSSPNYDE-KIDIYSYGIVLWELLT
 ... .   ..| ..|..|..||.|.||||||  |||.||  . ||.|||. |       | ..|| ..||||.|     |.  |.|..| |..|.|.|.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

SEKPYANENPATLPLKVIEHNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIIN---------YF
 . |.         .... ....       .  .| .|..|.   ||.||.  .. .         .|
GYPPFP-------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94035.m00029.AA TKL-ciliate2 203-454 36 1.6e-56 187.02 In-house 1-273 (273) Show / Hide 
Range on Protein: 203-454
Range on HMM: 1-273/273
Sequence Identity: 36% (101 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKILHLRQLSGADMERFRNEIFAMSTLTHPSLLPFCGYTQEAP-YCLATKFMENGSLFNILSTNPSFLSPTD
||   .| ||  | . | | . .  |||.|   .       .  | ||  ||  | || .  | |   . | .|.   .   |||. .|      |.  |
LEIQNKITEGGYGIIYKAKWREI--VVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWED

RTLIAYDVACGMEFLHSRG--VIHRDLK--------------------SLNILIDENKRGKISDFGFVRMK-SSVPMTGLVGTSHWMAPEILLSSPNYDE
|  || |.| |. .|||    .||||||                    |||.|.|.| | |..|||. |.|     ||  .||  |||||. ...  | |
RRRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEV-IKAFYYTE

KIDIYSYGIVLWELLTSEKPYANENPATLPLKVIEHNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIINYFT
| |..||.|.|||.   | || |        ||.  |||||||   | ..  |..|||    . |||| .||  . 
KADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase 94035.m00029.AA Dicty4-Unclassified 203-453 33 2.8e-56 191.26 In-house 1-263 (263) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-263/263
Sequence Identity: 33% (89 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKILHLRQLSGA--DMERFRNEIFAMSTLTHPSLLPFCGYTQEAP------YCLATKFMENGSLFNILSTNP
.   . ||.|   .| ||  |  |  ||.|..   . .     .. |. |.  .  . || |.   ||   .|      .|  . ||  | || .    |
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKP

SF----LSPTD--RTLIAYDVACGMEFLHSRGVIHRDLKSLNILIDENKRGKISDFGFVRMKS-SVPMTGLVGTSHWMAPEILLSSPNYDEKIDIYSYGI
|     ..  |     .| |.| || .||.| .||||.|| |||.| .   || |||  |  .    ||   ||  | .||.|     |  | |.|||..
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHE-SYNQKSDVYSYAM

VLWELLTSEKPYANEN-PATLPLKVIEHNLRPTIPEGTPIKMKTLIERCWSLSPEQRPSFHDIINYF
.|.||.| . ||     .  .   | .  ||| ||.  .  .| ||  ||. .|  ||.. .||.| 
MLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 94035.m00029.AA TyrKc 203-453 28 5.8e-55 189.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-280/280
Sequence Identity: 28% (81 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKILHLRQLSGADMERFRNEIFAMSTL--THPSLLPFCGYTQE--------APYCLATKFMENGSLFNILST
...||..|||  |.|.||. |   . ||.| |.        .| |..|.  |. |   || .. . |.  .         |... . .|..|.| . |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NPSFLSPTDRTLIAYDVACGMEFLHSRGVIHRDLKSLNILIDENKRGKISDFGFVRMKSSV-------PMTGL----VGTS----HWMAPEILLSSPNYD
.   |.. |   .....|||||.|||...|||||   |.|..||.. ||||||  |   .         .        | .     ||||| .     . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

EKIDIYSYGIVLWELLTS-EKPYANE----NPATLPLKVIEHNLRPTIPEG--------TPIKMKTLIERCWSLSPEQRPSFHDIINYF
.| |..|.|...||..|  ..|| ..     ...  .. ...  |. .|.          | .| .....||   ||.||.| .|. .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 94035.m00029.AA TK 203-453 15 9.4e-55 181.6 In-house 1-486 (486) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-486/486
Sequence Identity: 15% (75 aa)

LEFGKQIGEGISG---RVVKGKIKSTG-------------------------MVVAIKILHLR-QLSGADMER--------------FRNEIFAMST--L
...||..|||  |   .| ||. .. .                         . ||.|.|..    | ....               . .|.  |.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

THPSLLPFCGYTQEA-------------PYCLATKFMENGS----LFNILSTN-----------------------------------------------
 || .. . |.  .              |... . .|..|.    | . | ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------PSFLSPTDRTLIAYDVACGMEFLHSR------GVIHRDLKSLNILIDENKR-----------GKISDFG---
                            ...|.. ..  .....|||||.|||.      ...||||   |.|..||..            ||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FVR---MKSSVPMTGLVGTSH-------------------------WMAPEILLSSP--------NYDEKIDIYSYGIVLWELLTSE-KPYANEN
       |    ..    ..  ||.                          ||||| |..           . .| |..|.|...||..|   .||. . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PA---------TLPLKVIEHN--------------LRPTIPEGTP--------------IKMKTLIERCWSLSPEQRPSFHDIINYF
.          .  .. ..                .|.  |.. |                .  |. .||.. ||.||.| .. ...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 94035.m00029.AA CZAK 203-453 33 8.3e-52 178.43 In-house 1-279 (279) Show / Hide 
Range on Protein: 203-453
Range on HMM: 1-279/279
Sequence Identity: 33% (95 aa)

LEFGKQIGEGISGRVVKGKIKSTGMVVAIKILHL---RQLSGA-DMERFRNEIFAMSTLTHPSLLPF---CGYTQEAPYCLATKFMENGSLFNILSTNPS
|.||. ||.|  | | |.  .  | .|||||.|.   | ...  . . | .|.  || | ||  . |   |  . .   |  . .|. |||   |    .
LKFGQTIGQGFFGEVYKAYWR--GKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYF

FLSP--TDRTLIAYDVACGMEFLHS--RG--VIHRDLKSLNILIDENKR-------------GKISDFGFV--RMKSSVPMTGLVGTSHWMAPEILLSSP
.. .    .  .| |.| || .||   .   ..|||| | ||| |..                ||.|||    .|     ||  .|   |||||.     
YHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGE-

NYDEKIDIYSYGIVLWELLTSEKPYANENPATLP-LKVIEHNLRPTIPEGTPIKMK---TLIERCWSLSPEQRPSFHDIINYF
|| || |.||.|..||...|.. || |  |  .  |   | | || .|  .. . |    |||.||  .|. ||||  |. . 
NYTEKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYE-NYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL