Gene 85933.m00100 (T.vaginalis)

85933.m00100

Species: T.vaginalis
Alias: 85933.m00100, TvagK0185
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85933.m00100.AA Protein None 313 None Fasta, JSON
85933.m00100.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 85933.m00100.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 85933.m00100.AA S_TKc 14-257 29 6e-82 279.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 29% (76 aa)

LEFKNIIAEGGFGVIYLMYSEQYHSNFAMKKIPKERYNQEEYEIMASIDHPNTINLYKTYQFDNKIYMLMEYCPN---DLSNFLKGNPN------LDSQQ
 |. ..| .|.||. |. .    .  .|.|.|.  .  . | .|. . .||| ..|| ..|  ...|| ||||..   ||  ..| ..       ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

IKKYCYEVLIAIKACHDRNIAHSDIKPSNFLIDSYGRLKVCDFGLSRVYDGSLTNDMYKGTLYFMAPELLKKRHYNPLKADIWTIGVTFFYIATRRYPFY
...|.|... |.. ||...| | |.||.| |.|.  ..|.|||||.|..      . . ||...||||.|   .|.. |.|.| .|....  .... ||.
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

SSNPEILNNVIEAGVYSSFKVRNLELRQIISRCLDVLPEKRPTVDELLA-------HPYF
  ... . ..|             |....|..||.. ||||||. |.|.       ||.|
--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 85933.m00100.AA Pkinase 14-257 25 1.9e-70 245.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

LEFKNIIAEGGFGVIYLMYSEQYHSNFAMKKIPKERYNQ---------EEYEIMASIDHPNTINLYKTYQFDNKIYMLMEYCPN-----DLSNFLK--GN
.... .| .|.||. |. .   .   .|.|.|.|.. .           | .||....||| . || ... ...||| ||||..     ||. ...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PNL--DSQQIKKYCYEVLIAIKACHDRNIAHSDIKPSNFLIDSYGRL----KVCDFGLSRV--YDGSLTNDMYKGTLYFMAPELLKKRHYNPLKADIWTI
 ..  . ...|.|.|..| ... ||...| | |.||.|.|||. | .    |.|||||...  |  .  .. . ||...||||..... | . |.|.| .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTFFYIATRRYPFYSS-------NPEILNNVIEAGVYSSFKVRN--------------------LELRQIISRCLDVLPEKRPTVDELLAHPYF
|..... ...| ||...         ...... .. . ...   .                     |....|..||.. |.|||| ...| ||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85933.m00100.AA CAMK 19-257 19 2.3e-65 209.33 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-425/425
Sequence Identity: 19% (82 aa)

IIAEGGFGVIYLMYSEQYH------------SNFAMKKIPKERYN---------------------------------QEEYEIMAS-------IDHPNT
.. .|.||. .| .  .                .|.| |.|..                                   . |.||| .       .|||| 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INLYKTYQ------------FDNK--------IYMLM---EYCPN-----DLSNFLKGNPN---------------LDSQQIKKYCYEVLIAIKACHDRN
|.|| .|.            . .|        .|| |   |||..     || .... ...               .. .. ..|   .. |.. ||..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHSDIKPSNFLIDSY-----------------GRLKVCDFGLSRVYDGSLTNDM------------------------YKGTLYFMA-PELLKK-----
|.| |.|| | |.|.                  . .|..|||.....|..  | |                        . ||...|| ||.|..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------RHYNPLKADIWTIGVTFFYIATRRYPFYSS-------------NPEILNNVIEAGVYS-SFKVRNL-----------------------ELR
        . | . |.|.| .||  .   . ..|||..             |.. |   | .| |.   .                           | .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

QIISRCLDVLPEKRPTVDELLAHPYF
. |...| | ||||.|... |.|| .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85933.m00100.AA AGC 14-257 19 8.2e-61 154.95 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-395/395
Sequence Identity: 19% (77 aa)

LEFKNIIAEGGFGVIYLMYSE------QYHSNFAMKKIP-----------KERYNQEE------------YEIMASID----------HPNTIN-LYKTY
 ||. .| .|.||  ||          .    .|||..            ...... |             .|.. ..          ||. .. |. ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QFDNK--IYMLMEYCP----------N-DLSNFLK---GNPNLDSQQIKKYCYE-------VLIAIKACHD-RNIAHSD-IKPSNFLIDSYGRLKVCDFG
| ...  .|..|||.|            .|   |.   ..  .| .... |. |       .. |.   |. ..| | | .|| | |.|. | .| .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSRV--YDGSL-------------------------------------------------TNDMYKG--TLYFMAPELLKKRHYNPLKADIWT--IGVTF
|. .   ||.                                                  ..    |  |  .|||| |    |..  .|.|.   |. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

FYIATRRYPFYSSNPE----------ILNNVIEAGVYSSFKV--------------RNL--ELRQIISRCLDVLPEKRPT----------VDELLAHPYF
.   | . |||. ||.           . . |. | | ...               |..  |.. .|...| . ||||..          ..|. .||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 85933.m00100.AA CAMKL 14-257 24 8.9e-59 186.14 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-297/297
Sequence Identity: 24% (72 aa)

LEFKNIIAEGGFGVIYLMYSEQY-HSNFAMKKIPKERYNQE--------------------EYEIMASID---HPNTINLYKTYQFDNK------IYMLM
 ..   . .|.||.  |   ...     |.| | |.. . .                    |..|| ...   ||| | || ... ...      ||. |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPND---LSNFL--KGNPN--LDSQQIKKYCYEVLIAIKACHDRNIAHSDIKPSNFLIDSYG--RLKVCDFGLSRVYD-G----SLTNDMYKGTLYFM
|||..    | ...  .|...  ..  . ..|   .. |.. ||...|.| |||| | |.|. |   .|..|||.|  |. .      . ..  |.. .|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELLKK--RHYNPLKADIWTIGVTFFYIATRRYPFYSSNP--------EILNNVIEAGVYS-SFKVRNLELRQIISRCLDVLPEKRPTVDELLAHPYF
|||....  ..|.  |.||| .||. . . . ..||   .         . .. ...   |   ..    ..|..|.. | | ||||||..... || .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 85933.m00100.AA Ciliate-E2 14-257 22 1.4e-57 196.19 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

LEFKNIIAEGGFGVIYLM--YSEQYHSN---------------------FAMKKIPK---ERYNQEEYEI---------------MASIDHPNTINLYKT
 .| ..| .|.||..|..  ...|. ..                     .||| . |   |  .||....               . ...||| |..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YQ--FDNKIYMLMEYCPN-DLSNFLK------------GNPNLDSQQIKKYCYEVL---------------IAIKACHDRN-IAHSDIKPSNFLIDSYGR
.|   ||.||. ||||   ||  ..|            .  ... ..||.. ...|                |.. .| .| | | ||||.| |.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKVCDFGLSRVYDGSLT---------NDMYKG------------------------TLYFMAPELLKKRHY--------NPLKADIWTIGVTFFYIATRR
.|..|||||. || .           . |. .                        |...|||| |..  |           |.||| .||....  . .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

YPFYSSNPEILNNVIEAGVYS------------------SFKVRNLELRQIISR----CLDVLPEKRPT-VDELLAHPYF
.||         . |. . ..                  |.|   .|  ..|..    .|.. ||||.|  ...| ||.|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85933.m00100.AA ULK 14-257 24 7.8e-52 178.53 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-329/329
Sequence Identity: 24% (80 aa)

LEFKNIIAEGGFGVIYLMYSEQYH----SNFAMKKIPKERYNQEEYE---------------IMASID--------HPNTINLYKTYQFD--NKIYMLME
 . .... .| ||. |  . .. .      .| |.|.|.  ||...|               ||  ..        |||.. ||. .. .  | ||. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPN-DLSNFLKGNPN----------LDSQQIKKYCYEVLIAIKACHDRNIAHSDIKPSNFLIDSY------------GRLKVCDFGLSRVYDGS-----
||.  ||....| | .          |  |.......  | . |. |..|| | ||||.| ||.              |.||..|||.... | .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-LTNDM----YKGTLYFMAPELLK----KRHYNPLKADIWTIGVTFFYIATRRYPFYSS-NPEILNNVIEAGVY------------SSFK------VRNL
 ..       ..|| ..|||..|.    . .|.  |.||| .|. |... . ..|||.. |...|.....   .              |.      ..  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ELRQIISRCLDVLPEKRPTVDELLAHPYF
|....|.|.| . ...| . .||..|| |
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85933.m00100.AA Ciliate-E2-Unclassified 15-257 22 2.5e-50 172.8 In-house 2-352 (352) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-352/352
Sequence Identity: 22% (81 aa)

EFKNIIAEGGFGVIYLMYS-EQYHSNFAMKKIP------KERYNQEEYEIMASIDHPNTIN-----------------------LYKTYQF--DNKIYML
..  .| .||||..|...  .|.   .||| .       .  ..... ||| .... | ..                       ... |.|  ...||. 
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCPN-DLSNFLKGNPN-----------------LDSQQIK-----KYCYEVLIAIKACHDRN-IAHSDIKPSNFLIDSYG---RLKVCDFGLSRVYDG
||||.. ||....| ...                 .. ||.|     .|....| ... .|  | | | ||||.| |.|. |   ..|..|||.|. |. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

SLTNDMYK-----------------GTLYFM----APELLKK-RHYNP--LKADIWTIGVTFFYIATRRYPFYSSNPEILNNVIEA--------GVYSSF
.  .| ..                 ||...|    |||.|..  ....   |.|||. || .... . .||||. | |. ...|..         .|. .
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KVRNLELR--------------------QIISRCLDVLPEKRPTVDELLAHPYF
| .|.. .                    ......|.. |.||.| ...| ||.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85933.m00100.AA ULK 14-257 24 6.1e-50 172.24 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-324/324
Sequence Identity: 24% (79 aa)

LEFKNIIAEGGFG-VIYLMYSEQYH---SNFAMKKIPKERYNQEEYE---------------IMASID---HPN--TINLYKTYQFD--NKIYMLMEYCP
 . .... .| || . |  . .. .     .| |.|.|   |. ..|               ||  ..   |||  .. ||. .. .  | ||. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

N-DLSNFLKGNPN---------LDSQQIKKYCYEVLIAIKACHDRNIAHSDIKPSNFLIDSY------------GRLKVCDFGLSRVYDG-----SLTND
  ||....| | .         |  |.......  . . |. |..|| | ||||.| ||               |.||..|||.... |       ..  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

MY-----KGTLYFMAPELLK----KRHYNPLKADIWTIGVTFFYIATRRYPFYSSNPEILN----NVIEAG------VYS---SFK------VRNLELRQ
.      ||| ..|||..|.    . .|.  |.||| .|. |... . .|||.|. .. ..    . |. |      ..     |.      ..  |...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IISRCLDVLPEKRPTVDELLAHPYF
.|.|.| . ...| . .|...|| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85933.m00100.AA MARK 15-257 30 4.1e-43 138.88 In-house 2-262 (262) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-262/262
Sequence Identity: 30% (79 aa)

EFKNIIAEGGFGVIYLMYSEQYHSNFAMKKIPKERYNQ--------EEYEIMASIDHPNTINLYKTYQ--FDNK-IYMLMEYCPN-DLSNFLKGN--PNL
...  | .|.... .|  .  .. ..| | ..|.. |          | ||| ..|||| | |... .    .. ||. |||... .| ...|      |
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

DSQQIKKYCYEVLIAIKACHDRNIAHSDIKPSNFLIDSYG--RLKVCDFGLSRVYDGSLTNDMYKGTLYFMAPELLKKRHYNPLKADIWTIGVTFFYIAT
     ....  .. |.. ||..||.| |||| | |||. |    | .|||.|.        ..  ||. .||||...|. |.  |.|||. ||  ... .
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVC

RRYPFYSSN--PEILNNVIEAGVYSSFKVRNL--ELRQIISRCLDVLPEKRPTVDELLAHPYF
 ..||  ..   . |.  | .|.|. .    .  |.|..|.| | | ||.|||..|.. || .
GYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85933.m00100.AA STE 14-257 20 7.2e-42 145.41 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-359/359
Sequence Identity: 20% (74 aa)

LEFKNIIAEGGFGVIYLMYSE-----QYHSN-----------FAMKKIPKERYN----------------------QEEYEIMASID--HPNTINLYKTY
.|.  .| .|.||. |. .       . ...           .|.|....|. |                      ..| .||   .  ||| .. | .|
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

QFD-------NKIYMLMEYCP-NDLSNFLKGN----PNLD----------SQQIKKYCYEVLIA-IKACHDRNIAHSDIKPSNFLIDSYGRLKVCDFGLS
  .       ..... |||..   |. ..| .     .|.           .||...|...| .  .  |. .| | ||||.| |.      | ||||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

RVYDGSL-----------------TNDMYKGTLYFMAPELLKK------RHYNPLKADIWTIGVTFFYIATRRYPFYSSNPEILNNVIEAGV--------
   . |.                  ..   ||  .|||| ...       .|.  |.||| .| |    || ..|.   .|      |  .         
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----YSSFKVRN----------------------LELRQIISRCLDVLPEKRPTVDELLA--HPYF
       . .  .                       |... |..||.  |.||||...||   || .
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85933.m00100.AA CMGC 14-203 19 4.5e-37 118.71 In-house 1-342 (513) Show / Hide 
Range on Protein: 14-203
Range on HMM: 1-342/513
Sequence Identity: 19% (67 aa)

LEFKNIIAEGGFGVIYLMYS--------------EQYHSNFAMKKIP---KERYNQ-------------EEYEIMASI-----------------DHPNT
 |  . | || .|| |  .                ..    |.|||    .|.  .              | .|.  .                 .|.| 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

INLYKTYQFDN-----------------KIYMLMEYCPNDLSNFLKGNP---------NLDSQQ------------IKKYC------YEVLIAIK--ACH
..||  ....|                 ..|. .||...|| ...| |.         .|.  .            ||..       | .| ..|   ||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

DRN--IAHSDIKPSNFLIDS--------------------YGRLKVCDFGLSRVYDGSL----------------------TNDMYKGTLYFMAPELLK-
 ..  | | |.||.| ||..                     ||||.|||||.| |.                         ..  |  |..  |||.|  
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

KRHYN--------PLKADIWTIGVTFFYIATR-------RYPF
 .||.          . |.| .|  |. . |.       ..|.
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL
Kinase 85933.m00100.AA TyrKc 14-257 22 1.7e-14 11.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

LEFKNIIAEGGFGVIYL-MYSEQYHSNFAMKKIPKERYNQE---EYEIMASI--DHPNTINLYKTYQFD-------NKIYMLMEYCPN-DLSNFLKGNPN
.... .. || ||..|. ...     . | |.. ..   ..   | .|| ..  .||| ..||     .         ....|||.|. || ..|. . .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LDSQQIKKYCYEVLIAIKACHDRNIAHSDIKPSNFLIDSYGRLKVCDFGLSRVYDGS-------LTNDM-----YK--GTLYFMAPELLKKRHYNPLKA
 |  ..  ..|. .       |..|. | |.   | |... .. |..||||||  .          . ..      |    .  |||| .... ... | 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KS

DIWTIGVTFFYIATRRYPFYSS-------NPEILNNVIEAGVYSSFKV--------RNLELRQIISRCLDVLPEKRPTVDELLAHPYF
|.|  ||. . | |.  . |.        | |....| . .     .            |. ||...| .  ||.|||  |.  | .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 85933.m00100.AA CMGC 229-257 34 3e-09 25.57 In-house 485-513 (513) Show / Hide 
Range on Protein: 229-257
Range on HMM: 485-513/513
Sequence Identity: 34% (10 aa)

ELRQIISRCLDVLPEKRPTVDELLAHPYF
...  ....|   |.||.|... |.||||
QAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 85933.m00100.AA Pkinase_Tyr 53-112 27 7e-07 23.92 Pfam 52-120 (270) Show / Hide 
Range on Protein: 53-112
Range on HMM: 52-120/270
Sequence Identity: 27% (19 aa)

EEYEIMASI-DHPNTINLYKTYQ-FDNK--IYMLMEYCPN-DLSNFLKG----NPNLDSQQIKKYCYEV
.| .|| .. .||| ..||      .    ||. |||.|. || ..|.     ...|. ... ..|...
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQI
Kinase 85933.m00100.AA Pkinase_Tyr 135-151 47 0.801085 3.41 Pfam 143-159 (270) Show / Hide 
Range on Protein: 135-151
Range on HMM: 143-159/270
Sequence Identity: 47% (8 aa)

LIDSYGRLKVCDFGLSR
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LVTENNVVKICDFGLAR
Kinase 85933.m00100.AA Pkinase_Tyr 229-257 31 1.49731 2.49 Pfam 244-270 (270) Show / Hide 
Range on Protein: 229-257
Range on HMM: 244-270/270
Sequence Identity: 31% (9 aa)

ELRQIISRCLDVLPEKRPTVDELLAHPYF
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EIYDLMKQCWHYDPEDRPTFSEI--HEQL