Gene 96267.m00173 (T.vaginalis)

96267.m00173

Species: T.vaginalis
Alias: 96267.m00173, TvagK0912
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
96267.m00173.AA Protein None 151 None Fasta, JSON
96267.m00173.kin_dom Protein Kinase Domain None 138 None Fasta, JSON

Protein domain

Protein domains of 96267.m00173.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96267.m00173.AA Ciliate-E2 20-151 21 1e-14 46.93 In-house 115-307 (365) Show / Hide 
Range on Protein: 20-151
Range on HMM: 115-307/365
Sequence Identity: 21% (43 aa)

LIKGDDLYYYLEKN------------KVSDAEKLVWIYFIAD---------------QLETLHNNK-IIHRDICPKNIRIDTKHYPHIIDYDDVQKTDNP
...| ||..|...|            . .. | .  .. |..                || ||... |||||| | || .     . |||    .| |..
YCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDD

--------------------------------MQTSRRHGTGLYHSLEVIKSLD---------YTPASDIFALGGVIYYIMTGNEPNQAAQAVIKSCKIE
                                ... .  ||  | . |.... .         |. ..||..|| ..|. ..|. |    |  || |||.
NQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---QQQIKQCKID

L
.
F
Kinase 96267.m00173.AA Ciliate-E2-Unclassified 20-134 20 2.3e-12 39.25 In-house 102-267 (352) Show / Hide 
Range on Protein: 20-134
Range on HMM: 102-267/352
Sequence Identity: 20% (36 aa)

LIKGDDLYYYLEK------------------NKVSDAEKL-----VWIYFIADQLETLHNNK-IIHRDICPKNIRIDTKH---YPHIID-----------
...| || .|..|                  ..... . .      ... | . || || .. |||||| | || .| ..   |. |||           
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-------------YDDVQKTD--NPMQTSRRHGTGLYHSLEVIKSLDYT----PASDIFALGGVIYYIMTGN
             ... ..|   .|.  . .     | . ||...  |      ..||..|| ..|....|.
NCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q-----YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY
Kinase 96267.m00173.AA Pkinase 23-136 28 5.5e-11 39.94 Pfam 84-211 (293) Show / Hide 
Range on Protein: 23-136
Range on HMM: 84-211/293
Sequence Identity: 28% (37 aa)

GD----DLYYYLE---KNKV--SDAEKLVWIYFIADQLETLHNNKIIHRDICPKNIRIDTKHYP----HIIDYDDVQK--TDNPMQTSRRHGTGLYHSLE
|.    ||. |..   ....  |. |   ..| |.  || .|...|||||. | || || . ..    .|.|     .  . |   .. . ||  | . |
GGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPE

VIK-SLDYTPASDIFALGGVIYYIMTGNEP
||. . .|.|..|....| ..|. ..|. |
VIRGGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase 96267.m00173.AA Ciliate-E2b 8-81 33 1.6e-09 25.25 In-house 69-145 (272) Show / Hide 
Range on Protein: 8-81
Range on HMM: 69-145/272
Sequence Identity: 33% (26 aa)

KNDDRSLYVDFRLIKGDDLYYYLEKNK---VSDAEKLVWIYFIADQLETLHNNKIIHRDICPKNIRIDTKHYPHIID
. ||...|    ...| .|  ..   .   .|  . .  | .|   || |||..||.||| | || .| | |. .||
FKDDQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLID
Kinase 96267.m00173.AA Ciliate-E1 24-121 22 4.8e-08 22.76 In-house 81-202 (202) Show / Hide 
Range on Protein: 24-121
Range on HMM: 81-202/202
Sequence Identity: 22% (28 aa)

DDLYYYLE--------------KNKVSDAEKLVWIYFIADQLETLHNNKIIHRDICPKNIRIDTKHYPHIID-YDDVQ--KTDNPMQTSRRHGTGLYHSL
. |. ||.              .|. .. .|.  |. . |.|. ||...|||||| |.|| |. .   ...      .  |  .  |.  .. |  | . 
CSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPP

EVIK--------SLDYTPASDIF
|...        .  ..  |||.
EQYNCPEQEHNKNQKINYKSDIY
Kinase 96267.m00173.AA PKR 47-124 38 2.5e-07 22.13 In-house 132-210 (272) Show / Hide 
Range on Protein: 47-124
Range on HMM: 132-210/272
Sequence Identity: 38% (31 aa)

IADQLETLHNNKIIHRDICPKNI-RIDTKHYPHIIDYDDVQKTDNPMQ-TSRRHGTGLYHSLEVIKSLDYTPASDIFALG
|    . .|  |.||||. | ||  .|..|   | |.  |   .|  .   ||.||  | | | | | .|    ||.|||
IVKGVDYIHSKKLIHRDLKPSNIFLVDERHI-KIGDFGLVTALKNDGKSRTRRKGTLQYMSPEQIFSQHYGKEVDIYALG
Kinase 96267.m00173.AA Eta 51-139 30 1e-06 18.71 In-house 113-202 (261) Show / Hide 
Range on Protein: 51-139
Range on HMM: 113-202/261
Sequence Identity: 30% (27 aa)

LETLHNNKIIHRDICPKNIRIDTKHYPHIIDYDDVQK-TDNPMQTSRRHGTGLYHSLEVIKSLDYTPASDIFALGGVIYYIMTGNEPNQA
|  ||.. .| ||.   || .|     .. |.   .    | | |.   ||  |   |... ..| |. | .|.| ..| .|.|. |  |
LMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPFEA
Kinase 96267.m00173.AA PLK1 35-136 27 9e-06 14.7 In-house 96-198 (253) Show / Hide 
Range on Protein: 35-136
Range on HMM: 96-198/253
Sequence Identity: 27% (28 aa)

VSDAEKLVWIYFIADQLETLHNNKIIHRDICPKNIRIDTKHYPHIIDYDDVQKTDNP-MQTSRRHGTGLYHSLEVIKSLDYTPASDIFALGGVIYYIMTG
. . |   ..| |..  . ||||||||||.   |. .. .    | |.    | ..   .   . ||  |   ||..    .   ||...| ..| .. |
ITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFG

NEP
. |
QPP
Kinase 96267.m00173.AA Fer 20-64 45 1.3e-05 15.25 In-house 90-137 (283) Show / Hide 
Range on Protein: 20-64
Range on HMM: 90-137/283
Sequence Identity: 45% (22 aa)

LIKGDDLYYYLEKNK---VSDAEKLVWIYFIADQLETLHNNKIIHRDI
...|..|  || |||   |||.||.  .| .|. .| || ...|||||
FCNGGSLDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDI
Kinase 96267.m00173.AA PKN 51-136 34 1.9e-05 14.4 In-house 114-200 (260) Show / Hide 
Range on Protein: 51-136
Range on HMM: 114-200/260
Sequence Identity: 34% (30 aa)

LETLHNNKIIHRDICPKNIRIDTKHYPHIIDYDDVQKTDNPM-QTSRRHGTGLYHSLEVIKSLDYTPASDIFALGGVIYYIMTGNEP
|. ||..||| ||.   |. .||. |  | |.   .    .  .||   ||  .   ||.    || | | . || .|| .. |  |
LQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECP
Kinase 96267.m00173.AA IRE 99-133 36 0.000166 11.06 In-house 191-228 (292) Show / Hide 
Range on Protein: 99-133
Range on HMM: 191-228/292
Sequence Identity: 36% (14 aa)

GTGLYHSLEVIKS---LDYTPASDIFALGGVIYYIMTG
||. .| .|....      | . ||| .| |.||.||.
GTWGWHPPEMLQEFCQKRKTKSVDIFSMGCVFYYVMTN
Kinase 96267.m00173.AA Fer 107-136 32 0.001354 8.24 In-house 188-218 (283) Show / Hide 
Range on Protein: 107-136
Range on HMM: 188-218/283
Sequence Identity: 32% (10 aa)

EVIKSLDYTPASDIFALGGVIYYIMT-GNEP
|....  |.|..|... | ... |.| | ||
ETWQTGIYSPKTDVWSFGVMCWEIFTNGAEP
Kinase 96267.m00173.AA IRE 54-69 56 0.008156 5.1 In-house 132-147 (292) Show / Hide 
Range on Protein: 54-69
Range on HMM: 132-147/292
Sequence Identity: 56% (9 aa)

LHNNKIIHRDICPKNI
||  .|.|||. | ||
LHSQNIVHRDLKPHNI
Kinase 96267.m00173.AA Ciliate-E2b 107-136 31 0.080213 1.51 In-house 175-209 (272) Show / Hide 
Range on Protein: 107-136
Range on HMM: 175-209/272
Sequence Identity: 31% (11 aa)

EVIK-----SLDYTPASDIFALGGVIYYIMTGNEP
|.|.        || ..||...| . | .| |  |
EIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVP