Gene 84594.m00033 (T.vaginalis)

84594.m00033

Species: T.vaginalis
Alias: TvagK0285, 84594.m00033
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
84594.m00033.AA Protein None 1028 None Fasta, JSON
84594.m00033.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 84594.m00033.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84594.m00033.AA TKL 235-481 27 6e-90 305.13 In-house 1-364 (364) Show / Hide 
Range on Protein: 235-481
Range on HMM: 1-364/364
Sequence Identity: 27% (103 aa)

IGSGGFAEVWIGKYIPEN--------LTVAIKKIRPRD-------------------------DKDKVEQSYMSEVNTLASLRNPFLLQFVGYTKTEP--
||||||.||. ||.  ..         .||.||.. ..                         .  . ..    |.. . .|| | ..||.|| . .|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCVVTKYMPNGSLYSALRPENESDNLTQTQIAIIAYGIALGMNYLHE--------KGIIHRDLKSQNVLLDDNYY-------------
            .| |. |.|.|||.. |            |.  .|..||.||||||         ..||||||||.|.|.|.|.              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PVICDFGSCRNKNTIR--------------------TFTGQGGTANYMAPEFMKAE----------------KYDEKIDVYSYGILLWELVTKQSPFEG
 . ||||| .|....                      |   |.|| ..|||| .. .                .|.||.||||.||.|||..| . |...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

LIPPQIV---------CTVSMFNRRPDIP------------PDTNPLLKHLIENCWDRDPKERPPFADILKYL
. .....           |.  ..|| ||            ||. | .| |.. ||| ||..|| | .|||.|
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 84594.m00033.AA MLK 229-481 31 2.8e-76 259.74 In-house 1-291 (291) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-291/291
Sequence Identity: 31% (92 aa)

LKCDKIIGSGGFAEVWIGKYIPEN---LTVAIKKIRPRDDKDKVE-----QSYMSEVNTLASLRNPF----LLQFVGY-TKTEP-YCVVTKYMPNGSLYS
..  ..||||.| .|| |..  ..    .||.|..| | . ||..     .    |.. |. |. |       ||.|  ..... .|.|. |...||||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ALRP-ENESD----------NLTQTQIAIIAYGIALGMNYLHEKG---IIHRDLKSQNVLLDD------NYYPVICDFGSCRNKNTI-RTFTGQGGTANY
 |.  .....          . .  ... .|. .| ||.|||..    ||||||||.|.|.|.      .   .|||||  | ....  . ... ||. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPEFM---KAEKYDEKIDVYSYGILLWELVTKQSPFE-GLIPPQIVCTVSMFNRRPDIPPDTNPLLKHLIENCWDRDPKERPPFADILKYL
||||     ..|||.|| ||.|.|..|||..|.. |.. .. | .|   | . . || ||.. .. .| |...||. ||..|| |. |...|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 84594.m00033.AA TKL-Unique 233-481 33 1.5e-71 243.97 In-house 3-290 (290) Show / Hide 
Range on Protein: 233-481
Range on HMM: 3-290/290
Sequence Identity: 33% (98 aa)

KIIGSGGFAEVWIGKYIPENLTVAIKKIRPRDDKD-KVEQSYMSEVNTLASLR-NPFLLQFVGYTK----TEP-YCVVTKYMPNGSLYSALR---PEN--
. ||.||...|  ||.      ||||.. |  |.  ...|   .|||..  |.  |......||..    ..| .| |. |.| ||||. |    . |  
NKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

--ESDNLTQTQIAIIAYGIALGMNYLHEKG--IIHRDLKSQNVLLDDN-----YYPVICDFGSCRNKNTI-RTFTGQG---------GTANYMAPEFMKA
  .. .|.  |.  .|  ||.||.||| ..  ||||||||.|.|.| |     .   ||||| ......| .....           |....|||| .. 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--EKYDEKIDVYSYGILLWELVTKQS------PFEGLIPPQIVCTVSM--FNRRPDIPPDTNPLLKHLIENCWDRDPKERPPFADILKYL
  ..|.||.||||.|| |||..| .       |..|. . |.  .|     | || ||.. .. ...||. ||..|| .|| | .|...|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 84594.m00033.AA Pkinase 229-481 25 4.1e-70 244.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-293/293
Sequence Identity: 25% (74 aa)

LKCDKIIGSGGFAEVWIGKYIPENLTVAIKKIRPRDDKDKVEQSYMS--EVNTLASLRNPFLLQFVGYTKTEPYCV-VTKYMPNG----SLYSALRPENE
... ..||||.|..|.... . .. .||.|.|. |..|....|.     |.  ...|. |. ... ..  .....  |. |...|    .|.. ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

SDNL--TQTQIAIIAYGIALGMNYLHEKGIIHRDLKSQNVLLDDNYYP----VICDFGSCRN--KNTIRTFTGQGGTANYMAPEFMK-AEKYDEKIDVYS
. ..  .  ..  ..| |. |..|.|..||||||||..|.|.|.|...     |||||...       . .|.  || .|||||  . ...|. |.|..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YGILLWELVTKQSPFEGL------IPPQIVCTVSMFNRRPDIPPDTN-------------------PLLKHLIENCWDRDPKERPPFADILKY--L
.|..|.|..... || |        . |..| . .   . |.| . .                   . .|..|..|...|||.|| ...||.   .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84594.m00033.AA Dicty4 229-483 35 5.2e-65 215.79 In-house 1-277 (277) Show / Hide 
Range on Protein: 229-483
Range on HMM: 1-277/277
Sequence Identity: 35% (99 aa)

LKCDKIIGSGGFAEVWIGKYIPENLTVAIKKI--RPRDDKDKVEQSYMSEVNTLASLRNPFLLQFVGYTKT---EP--YCVVTKYMPNGSLYSALRP---
.. ...||.|.|.||  |.       ||.||   .  ..  .  ..   ||. ....|.| ...| |.      .|   | || ||| |.||| |.    
INIEQRIGKGSFGEVYKGTW--RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

-ENESDNLTQTQIAI---IAYGIALGMNYLHEKG--IIHRDLKSQNVLLDDNYYPVICDFGSCRNKNTIR--TF--TGQGGTANYMAPEFMKAEKYDEKI
   .|. |  . |     .|  .|.|||.||.    |||||||| | | |.|.   .||||  . . ..   ..  ... ||. .|||| |  . |.|| 
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSYGILLWELVTKQSPFE--GLIPPQIVCTVSMFNRRPDIPPDTNPLLKHLIENCWDRDPKERPPFADILKY--LCT
||||.||.|||..|.| |.   .  ..|.|  |     || ||... | .||||. ||| ||. || |. |...  | .
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 84594.m00033.AA S_TKc 229-481 24 1.6e-59 204.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

LKCDKIIGSGGFAEVWIGKYIPENLTVAIKKIRPRDDKDKVEQSYMSEVNTLASLRNPFLLQFVGYTKTEPYCVVTKYMPN--GSLYSALRPENESDN--
 .  ..||.|.|..|. .. .  .  ||||.|.         .. ..|.. | . . |.. .. ..  .. ...|. |...  |.|.. ..  .   .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTQTQIAIIAYGIALGMNYLHEKGIIHRDLKSQNVLLDDNYYPVICDFGSCRNKNTIRTFTGQGGTANYMAPEFMKAEKYDE-KIDVYSYGILLWELVT
 ..  ... ..| |.....|.|..|||||||| .|.|||.     |||||..|        | . || .||||| .   .|.  |.|..| |..|.|...
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KQSPFEGLIPPQIVCTVSMFNRRPDIPPDTNPLLKHLIENCWDRDPKERPPFADILK---------YL
 . ||.    .| .  . .            | .|..|..|...||..||   ..|.         ..
GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84594.m00033.AA TyrKc 229-481 26 2.6e-57 197.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

LKCDKIIGSGGFAEVWIGKYIPENLTVAIKKIRPRDDKDKVEQSYMSEVNTLASL--RNPFLLQFVGYTKT--------EPYCVVTKYMPNGSLYSALRP
.. .|..|.| | ||. |...   ..||.|....       ..  |.| . . .|  ..| .....|.  .        ||...|. |||.|.| . || 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ENESDNLTQTQIAIIAYGIALGMNYLHEKGIIHRDLKSQNVLLDDNYYPVICDFGSCRNKNTI-------RTFTG----QG---GTANYMAPEFMKAEKY
  .   |.  .   ... || ||.|||.|..|||||   |.|...|.   |.||| .|.            . .     .|        |||| ..  |.
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DEKIDVYSYGILLWELVTK-QSPFEGL----IPPQIVCTVSMFNRRPDIPPD--------TNPLLKHLIENCWDRDPKERPPFADILKYL
 .| ||.|.|...||. |  |.| .|     ...| |    .  .|...||.          . .  ... ||..||..|| |..| ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84594.m00033.AA STE 229-481 19 3.1e-54 186.5 In-house 1-359 (359) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

LKCDKIIGSGGFAEVWIGKYI------PENLT---------VAIKKIRPRDDK---------------DKVEQSYMSEVNTLASLR--NPFLLQFVGYTK
... ..||.|.| .|  ....      . . .         .|||... ....               .. .|... |....  ..   |.  .. |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TEP--------YCVVTKYMPNGSLYSALR---PENESDN--------LTQTQIAIIAYGIALG-MNYLHEKGIIHRDLKSQNVLLDDNYYPVICDFGSCR
 |          ...  ||..||| . ..     ....|        .  .|||.|.. |  | ..|||...|||||.|..|.||       .|||| | 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

NKNT-------------------IR-TFTGQGGTANYMAPEFMKA------EKYDEKIDVYSYGILLWELVTKQSPFEGLIPPQIVCTVSMF--------
. .                     | ||.|      .|||| ..        .||.| |..| |....|..| . |.  . |..      .         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP----WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

------NRRPDIPPDTN-------------------PLLKHLIENCWDRDPKERPPFADILK----YL
      .  | .|...                    | .|. |..| ..||..||   . ||     .
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 84594.m00033.AA HH498 229-481 30 4.5e-53 166.4 In-house 1-284 (284) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-284/284
Sequence Identity: 30% (87 aa)

LKCDKIIGSGGFAEVWIGKYIPENLTVAIKKIRPRDDKDKVE------QSYMSEVNTLASLRNPFLLQFVGYTKTEP--YCVVTKYMPNGSLYSAL----
..  ..|||| | .|  |..   |  ||.|  |      | .        .  ||  .  | .|   |||. .  .|    .|| |  ||||.| |    
IEFHEKIGSGSFGKVYKGEW--RNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

------RPENESDN-----LTQTQIAIIAYGIALGMNYLHE---KGIIHRDLKSQNVLLDDNYYPVICDFGSCRNKNTI--RTFTGQGGTANYMAPEFMK
         |  ..     .    . .|.  .| ||||||.   . |||||| |.|.|.. .   |. |||  | .. .   . | | |   .||||  .
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-AEKYDEKIDVYSYGILLWELVTKQSPFEGLIPPQIVCTVSMFNRR--PDIPPD----TNPLLKHLIENCWDRDPKERPPFADILKYL
   ||..|.||.||.. .||. |   ||  . |  .     | ...  | ||             ||  ||.  | .|| |..|.  |
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKP--AAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 84594.m00033.AA TK 229-481 16 8.5e-53 174.92 In-house 1-486 (486) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-486/486
Sequence Identity: 16% (80 aa)

LKCDKIIGSGGFA---EVWIGKYIPEN-------------------------LTVAIKKIRPRDDKDKVEQSY---------------MSEVNTLAS--L
..  | .|.| |    ||. |.....|                          .||.| ... |. .. |.                 ..|   . .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RNPFLLQFVG-YTKT------------EPYCVVTKYMPNGS----LYSALR--PENESD-----------------------------------------
. | .....|  |.             ||...|. |||.|.    | . ||  ......                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------NLTQTQIAI-------------------IAYGIALGMNYLHEK------GIIHRDLKSQNVLLDDNYY-----------PVICDFG----
           ||...                      ... || || |||.|      ...||||   |.|...|.              |.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----SCRNKNT--IRTFTGQGGTAN-------------------------YMAPEFMK---------AEKYDEKIDVYSYGILLWELVT--KQSPFEGLI
     .|  .     . ....||.                          .|||| ..           |. .| ||.|.|.|.||..|  .. . .|. 
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

P--------PQIVCTVSMFN--------------RRPDIPPDTN--------------PLLKHLIENCWDRDPKERPPFADILKYL
         .| |.                     |.  ||.                ...  |.  ||..||..|| |......|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 84594.m00033.AA Dicty4-Unclassified 229-481 32 9.3e-53 179.01 In-house 1-263 (263) Show / Hide 
Range on Protein: 229-481
Range on HMM: 1-263/263
Sequence Identity: 32% (86 aa)

LKCDKIIGSGGFAEVWIGKYIPENLTVAIKKIRPRDDKDK--VEQSYMSEVNTLASLRNPFLLQFVGYTKTEP------YCVVTKYMPNGSLYSALR---
.. |. || | |..|  |     .  ||.||.    .|    . | .  ||  | |.  | |..  ||    |      .|.|.  |. | |        
IQIDQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSKP

-PENESDNLTQTQIAIIAYGIALGMNYLHEKGIIHRDLKSQNVLLDDNYYPVICDFGSCRNKNTIRTFTGQGGTANYMAPEFMKAEKYDEKIDVYSYGIL
   . .  |  | |  .|  || || .|| . .||||.|| |.|.| ..   | |||  |      . |  .||    .|| .. | |  | |||||...
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWELVTKQSPFEGLI-PPQIVCTVSMFNRRPDIPPDTNPLLKHLIENCWDRDPKERPPFADILKYL
|.||.|   |. .   .  .   |     || ||    . .| ||  ||  ||. || . .| .||
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 84594.m00033.AA LRRK 229-483 27 1.7e-50 174.1 In-house 1-351 (351) Show / Hide 
Range on Protein: 229-483
Range on HMM: 1-351/351
Sequence Identity: 27% (96 aa)

LKCDKIIGSGGFA-EVWIGKYIP-------------EN-------------LTVAIKKIRP--------------------------------RDDKDKV
||. . ||.|||. .|  .|..              ..              .|||||.                                   .|. ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EQSYMSEVNTLASLRNPFLLQFVGYTKTEPYCVVTKYMPNGSLYSALRPENESD------NLTQTQIAIIAYGIALGMNYLHEKG--IIHRDLKSQNVLL
 ...  ||  . .|. | ... .|..  .|.| |. |.|.|.||. |. . ..       ... . .  ||. || ||.||| .   |||||||| |.||
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---DDNY------YPV---ICDFGSCR-NKNTIRT--FTGQGGTANYMAPEFMKAE---KYDEKIDVYSYGILLWELVTKQ-SPFEGLI-PPQI--VCTV
   ..|.       .|   |.|||  |    ....  . | .|.  .|||| |...    |.||.|.||.|..||||.| |  ||...  . ..    ..
WSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

SM---FNRRPDIPPD-TNP-----LLKHLIENCWDRDPKERPPFADILKYLCT
.      .|| ||..  .|      .. ||. ||. |||.|| | .|.| | .
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 84594.m00033.AA Dicty5 303-485 37 1.6e-49 168.57 In-house 77-260 (260) Show / Hide 
Range on Protein: 303-485
Range on HMM: 77-260/260
Sequence Identity: 37% (69 aa)

VTKYMPNGSLYSALRPENE--SDNLTQTQIAIIAYGIALGMNYLHEKGIIHRDLKSQNVLLDDNYYPVICDFGSCRNKNTIRTFTGQGGTANYMAPEFMK
|| |  |||| ..|.        ..   |.  .| .|| .| .|| ..|||||||| |.|.  |.   | |||  |.      .|   || ..||.|  .
VTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFN

AEKYDEKIDVYSYGILLWELVTKQSPFEGLIPPQIVCTVSMFNRRPDIPPDTNPLLKHLIENCWDRDPKERPPFADILKYLCTNN
   |..| ||||.|| |||. |. .|.. .    |   | |   || ||.|       ||. ||   |. || |  |.||.    
GQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMV-MKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 84594.m00033.AA Pkinase_Tyr 229-373 29 3.2e-33 113.14 Pfam 1-156 (270) Show / Hide 
Range on Protein: 229-373
Range on HMM: 1-156/270
Sequence Identity: 29% (47 aa)

LKCDKIIGSGGFAEVWIGKYI----PENLTVAIKKIRPRDDKDKVE---QSYMSEVNTLASL-RNPFLLQFVGYTK--TEP--YCVVTKYMPNGSLYSAL
.. .| .|.| | ||. |..      ....||.|..  ... .. .   .. |.|.... .| ..| .....|      ||  ...|. |||.|.|.. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RPE-NESDNLTQTQIAIIAYGIALGMNYLHEKGIIHRDLKSQNVLLDDNYYPVICDFG
|   .. ..||  ..  ... || ||.||..|..|||||   |.|...|    |||||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 84594.m00033.AA Pkinase_Tyr 394-481 31 1.2e-18 63.82 Pfam 181-270 (270) Show / Hide 
Range on Protein: 394-481
Range on HMM: 181-270/270
Sequence Identity: 31% (28 aa)

MAPEFMKAEKYDEKIDVYSYGILLWELVT-KQSP-FEGLIPPQIVCTVSMFNRRPDIPPDTNPLLKHLIENCWDRDPKERPPFADILKYL
|||| ..  |. .| ||.|.|.|.||..|  ..| ..|. . ...  .   ..| ..|... . . .|.  ||. ||..|| |..|.  |
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL