Gene 81312.m00091 (T.vaginalis)

81312.m00091

Species: T.vaginalis
Alias: TvagK0143, 81312.m00091
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81312.m00091.AA Protein None 309 None Fasta, JSON
81312.m00091.kin_dom Protein Kinase Domain None 247 None Fasta, JSON

Protein domain

Protein domains of 81312.m00091.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 81312.m00091.AA S_TKc 13-259 28 8.4e-69 235.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-231/231
Sequence Identity: 28% (75 aa)

LKYLAQIGSGTYGSVYLVYSMQYRAKFALKVTRKKYFKEEEFESLQQLDSPNVVRLYKCERKNTMLYLLMEYCPF---TVFNKIKINGE------IKEKQ
 . | .||.|..|.||...      ..|.|. .     . | . |.. . ||.|.|| . .  . ||. ||||.    ..|  || .|       . | .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

VLNVAYDILQALCICHSRRISHGDIKPNNIIIDGFGRAKLCDFGMSITQSDSNEDNLTTQICGSFPFAPPEIYLKKTYDRFKADIYSFGVTVFALLTGKL
.  ..| |..||  |||..| | |.|| || .|   . |.||||..            | .||.  . .||.     |...|.|..|.|.... .|.|. 
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYP

PFKGKTPEEAIANIINGKFTLRLVENQDIADLIFRCMHSNPEKRPNATELIN-------HPAF
||     .... ..|           ..  |.| .|.. .||||| | |. .       || |
PFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81312.m00091.AA CAMK 18-259 17 2.6e-63 202.56 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-259
Range on HMM: 1-425/425
Sequence Identity: 17% (75 aa)

QIGSGTYGSVYLVYSMQYR------------AKFALKV---------------------------------TRKKYFKEEEFESLQQ-------LDSPNV
..|.|..| |.|..  .               |.| |.                                  ... . . | | ...       || ||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYK---------------CERK-----NTMLYLLM---EYCP-----FTVFNKIKINGE---------------IKEKQVLNVAYDILQALCICHSRR
..||                  .|     ....|. |   |||.     . .|..|. .|                ..|...  .   |..|.  |||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ISHGDIKPNNIIIDGF-----------------GRAKLCDFGMSITQSDSN---------------------EDNLTTQICGSFPFAP-PEIYLK-----
| | |.|| || .|                   .  |..|||...   ...                     |. . .  ||. .... ||. ..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KTYDRFKADIYSFGVTVFALLTGKLPFKGKTPEEAIA-------------NIINGKFTLR--LVEN----------------------QDIA
        |.|. .|.|. | ||  ...|.|..|| |.. .| .              .|..||..     . .                      |.  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIFRCMHSNPEKRPNATELINHPAF
||| ...  .||||.....  ||| .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81312.m00091.AA Ciliate-E2 13-259 23 1.5e-62 213.5 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

LKYLAQIGSGTYGSVYLV--------------------------YSMQYRAKFALKVTRKKYFKEEEFES---------------LQQLDSPNVVRLYKC
 | . .||.|..||||..                          . ... |.  .|   ....| |. .                |.||..||....| |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ER--KNTMLYLLMEYCPF-TVFNKIKIN-----------GEIKEKQVLNVAYDILQ---------------ALCICHSRR-ISHGDIKPNNIIIDGFGRA
    ... .|| ||||   . |  ||.|           . ..||..... . |||               ||  .||.  | | ||||.||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGMSITQSDSNED-----------------------------NLTTQICGSFPFAPPEIYLKKTYDR--------FKADIYSFGVTVFALLTGKLP
|..|||.|  ..|.|..                             |.. .|||. .. .|||. .| ||         .|.||.|.||. . .|.||.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FKGKTPEEAIANIINGKFTLR------------------LVENQDIADLIFR----CMHSNPEKRPN-ATELINHPAF
|        . .|...|. ..                  .   |.  ||| .    ..  .||||.. . ...||| |
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81312.m00091.AA Pkinase 13-259 26 2.7e-58 204.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

LKYLAQIGSGTYGSVYLVYSMQYRAKFALKVTRKKYFKE---------EEFESLQQLDSPNVVRLYKCERKNTMLYLLMEYCPF-----TVFNKIK--IN
.. . .||||..|.||. .   .. ..|.|. .|.  |.          | . .. |..||.|||| . . .. .|. ||||.        |  |.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GEI--KEKQVLNVAYDILQALCICHSRRISHGDIKPNNIIIDGFGRA----KLCDFGMSITQSDSNEDNLTTQICGSFPFAPPEIYLKKTYDRFKADIYS
| .   |... ...| ||..|  |||..| | |.|| || ||  |      |.|||| .   .    .  .| .||. ....||. .. .|.  |.|..|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGVTVFALLTGKLPFKGK------TPEEAIANIINGKFTLRLVEN---------------------QDIADLIFRCMHSNPEKRPNATELINHPAF
.|.... .|.|..||.|.      .. . |..|  ...     .                      ..  |.| .| . .|.|||.|... .|| |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81312.m00091.AA CAMKL 13-259 27 6.2e-56 176.92 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-297/297
Sequence Identity: 27% (83 aa)

LKYLAQIGSGTYGSVYLVYSMQY-RAKFALKVTRKK-----YFKEE---------------EFESLQQLD---SPNVVRLYKCERKNTM------LYLLM
 . . ..| |..| | |    .. . | | |.  ||      ...                | . ...|.    ||...|| .    ..      .|| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPFT---VFNKIKINGE----IKEKQVLNVAYDILQALCICHSRRISHGDIKPNNIIIDGFG--RAKLCDFGMSITQSD--SNEDNLTTQICGSFPFA
|||.      |..|. .|.    ..|..       |. |.  |||..| | |||| || .|  |   .|..|||.|. . .   ..... .  ||| |..
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEIYLK--KTYDRFKADIYSFGVTVFALLTGKLPFKGKTPE-------EAIANIINGKFTLRLVENQ-DIADLIFRCMHSNPEKRPNATELINHPAF
.|||...  | || .|.|| | ||. .|...|.|||.. | .       .    |. | .  .      |  ||| . .  ||||||.. .. ||| .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81312.m00091.AA Ciliate-E2-Unclassified 14-259 20 8.1e-56 191.76 In-house 2-352 (352) Show / Hide 
Range on Protein: 14-259
Range on HMM: 2-352/352
Sequence Identity: 20% (73 aa)

KYLAQIGSGTYGSVYLVYSMQYRAKF-------ALKVTRKKYFKE---------EEFE---------------SLQQLDSPNVVRLYKCERKNTMLYLLM
| . |||.| .|.||...  .   ..         ..  .|. ..         |...               .|.....|..|... |...   .|. |
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCP-FTVFNKIKINGE-----------------IKEKQVL-----NVAYDILQALCICHSR-RISHGDIKPNNIIIDGFG---RAKLCDFGMSITQSDS
|||.  . .. ||...                  . |.|..     . .. |||.|. .|.   | | ||||.||..|  |   . |..||| |. . ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

NE-------------DNLTTQICGSFPFA----PPEIYLKKTYDR---FKADIYSFGVTVFALLTGKLPFKGKTPEE----------------AIANIIN
|.             .......||.  .     .||.. .. ||    .|.||.|.||  ...|.|..||.... |.                 . ||..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GKFTLRLVEN----QDIA--------DLIFRCMHSNPEKRPNATELINHPAF
...  .  ..    ...         ||. ...  ||.||... ...||| |
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81312.m00091.AA STE 13-259 20 9e-50 171.67 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-359/359
Sequence Identity: 20% (75 aa)

LKYLAQIGSGTYGSVYLVYSM------QYRAK---------FALKVTRKKYFK----------------------EEEFESLQQLD--SPNVVRLYKCER
.. . .||.|..|.||. . .      .   .         .| |. ...  .                      ..| . .....  .||.|. | |. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KN-------TMLYLLMEYCPF-TVFNKIKINGEIK--------------EKQVLNVAYDILQA-LCICHSRRISHGDIKPNNIIIDGFGRAKLCDFGMSI
|.       . |.. |||..  ..   || .....              |.|.  ....||.. |   || .| | |||| || .     .|||||| . 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

TQSDS--------------NEDNLTTQICGSFPFAPPEIYLK------KTYDRFKADIYSFGVTVFALLTGKLPFKGKTPEEAIANIING----------
  .||              . .  .. ..|.  .  ||. ..      | ||. |.||.|.| |.  ..||| |.   .| .|. .|...          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT-KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----KFTLRLVEN---------------------QDIADLIFRCMHSNPEKRPNATELIN--HPAF
    .   .| ..                     ..  | | .|   .|.|||.|..|..  || .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81312.m00091.AA MARK 14-259 32 7.2e-47 151.32 In-house 2-262 (262) Show / Hide 
Range on Protein: 14-259
Range on HMM: 2-262/262
Sequence Identity: 32% (87 aa)

KYLAQIGSGTYGSVYLVYSMQYRAKFALKVTR-KKYFK-------EEEFESLQQLDSPNVVRLYKCER--KNTM-LYLLMEYCPFT-VFNKIKIN--GEI
| | .|| |.|. |.|. .  .. |.|.|.   .| ..       . | | ...|| ||...|..      ..  .|| |||.. . ... ||    | .
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

KEKQVLNVAYDILQALCICHSRRISHGDIKPNNIIIDGFG--RAKLCDFGMSITQSDSNEDNLTTQICGSFPFAPPEIYLKKTYDRFKADIYSFGVTVFA
.|.        |. |.. |||..| | |||| || ||  |   .|..|||.||     ..... .  ||. |...||| ||| || .|.||.| ||  ..
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSIC---IPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

LLTGKLPFKGKT--PEEAIANIINGKFTLRLVENQDIADLIFRCMHSNPEKRPNATELINHPAF
...|..||.|.|   .|   .| .||..       .. .|| | .  |||.|| ..|. .|| .
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 81312.m00091.AA ULK 13-259 21 1.3e-44 154.49 In-house 1-324 (324) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-324/324
Sequence Identity: 21% (69 aa)

LKYLAQIGSGTYG-SVYLVYSMQY---RAKFALKVTRKKYFKE---------------EEFESLQQLD---SPN--VVRLYKCERKNTM--LYLLMEYCP
     ..|.|..|  ||  . ..      ..| |.  ||....                | . ...|.   .||  .|.||.. .  .   .|. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

F-TVFNKIKINGE---------IKEKQVLNVAYDILQALCICHSRRISHGDIKPNNIIIDGF------------GRAKLCDFGMSIT-QSDSNEDNLTTQ
  . .. || |..         . |...... ..|....   |.. | | |||| || |               |..|..||| . . .... |......
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IC------GSFPFAPPEIYL----KKTYDRFKADIYSFGVTVFALLTGKLPFKGKTPEEAIAN--------------IINGKFTLRLVE-----NQDIAD
..      |.  .  |.|      .| |. .|.||.|.|.  . .|.|| ||..  ... . .              | | ..  ....      ... |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIFRCMHSNPEKRPNATELINHPAF
|| |..  ....| . .|..||| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81312.m00091.AA ULK 13-259 21 1.4e-43 149.99 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-329/329
Sequence Identity: 21% (72 aa)

LKYLAQIGSGTYGSVYLVYSMQYR----AKFALKVTRKKYFKE---------------EEFESLQQLD----SPN----VVRLYKCERKNTM--LYLLME
     ..|.|..| ||  . ..       |.| |.  |.....                | . ...|.    ..|    .|.||.. .  .   .|. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPF-TVFNKIKINGE----------IKEKQVLNVAYDILQALCICHSRRISHGDIKPNNIIIDGF------------GRAKLCDFGMSIT-QSD--SNE
||.  . .. || |..          . |...... ..||...   |...| | |||| || |.              |..|..||| . . ..|  ...
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

DNLTTQ----ICGSFPFAPPEIYL----KKTYDRFKADIYSFGVTVFALLTGKLPFKGKTPEEAIANIINGKFTLRLVEN--------------------
...|.     .||.  .  |.|      .| |. .|.||.|.|.  . .|.|| ||..  ... . .||.  . .... .                    
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

QDIADLIFRCMHSNPEKRPNATELINHPAF
... ||| |..  ....| . .||.||| |
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 81312.m00091.AA TKL 19-257 19 1e-41 144.9 In-house 1-364 (364) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-364/364
Sequence Identity: 19% (71 aa)

IGSGTYGSVYLVYSMQYR--------AKFALKVTRKKY--------------------------------FKEEEFESLQQLDSPNVVRLYK--CERKNT
||||..| ||  . .. .           | |. ....                                |.|||  .. .|. ||.|...   |. ...
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

M-----------LYLLMEYCPFTV-FNKIKINGEIKEKQVLNVAYDILQALCICHSRR--------ISHGDIKPNNIIIDGFGR--------------AK
.           |.. |||||    .. .         | .. |.|| ....  ||..        | | |.|..|| .|  ..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LCDFGMSITQSDSNEDNL-----------------TTQICGSFPFAPPEIYLKKTYDR---------------FKADIYSFGVTVFALLTGKLPFKGKTP
.|||| | . | |...|                  |  .||.. . .||.  ......                |.|.||||.  . .||...|...  .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

EEAIAN-------IINGKFTLRLVEN----------------QDIADLIFRCMHSNPEKRPNATELINHP
.. |..       .....  ||.                   .....|. .|....|||||...|.. . 
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 81312.m00091.AA RSK 16-259 28 3.1e-39 136.67 In-house 1-278 (278) Show / Hide 
Range on Protein: 16-259
Range on HMM: 1-278/278
Sequence Identity: 28% (81 aa)

LAQIGSGTYGSVYLVYSM---QYRAKFALKVTRKKYFKE---------EEFESLQQLD-SPNVVRLYKCERKNTMLYLLMEYCP----FTVFNKIKINGE
| . | | ||.|.|.      . .  .| || .|. ..          .| . |.    .|..|.|.   . .. ||| ||||.    ||   | |. | 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IKEKQVLNVAYDILQALCICHSRRISHGDIKPNNIIIDG---FGRAKLCDFGMSITQSDSNEDNLTTQICGSFPFAPPEIYL----KKTYDRFKADIYSF
. |. .  ... |  |.   |.. | | |.|| ||. |     |. ||.||| .  |.. .. ..|   |..  ...||.      ....|.  .|..|.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCK-QFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDK-ACDWWSL

GVTVFALLTGKLPFKG---KTPEEAIANIINGKFTLRLVENQDIA----DLIFRCMHSNPEKRPN-----ATELINHPAF
||  . .|||..||.|   ....| ...| .|||.|.. ..| .     ||| ...| .|.||..     | |. .|| |
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 81312.m00091.AA TyrKc 13-259 21 6.6e-15 18.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-259
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

LKYLAQIGSGTYGSVYL-VYSMQYRAKFALKVTRKKYFKEEEFES----LQQL--DSPNVVRLYKCERKN-------TMLYLLMEYCPFTVFNK-IKING
.. . ..|.| .| ||. ...     . | |. ..    .|.| .    . .|  . ||.|||| . ..          |...|||.|    .. .. ..
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

E-IKEKQVLNVAYDILQALCICHSRRISHGDIKPNNIIIDGFGRAKLCDFGMSITQSDS-----NEDNLTTQ--ICGS--FPFA--PPEIYLKKTYDRFK
. .. |. |. ...| .     ||... | |.   |. ..  ...| .|||.|    |      ..|  ...   .|   .|    .||   ....  .|
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TK

ADIYSFGVTVFALLT-GKLPFKG-----KTPEEAIANIINGKFTLRLVE---------NQDIADLIFRCMHSNPEKRPNATELINHPAF
 |..||||. . ..| |. |  |     ....|.|... .|.   .  .          ... ... .| | .||.||. .|.  |  |
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 81312.m00091.AA Pkinase_Tyr 185-259 32 4e-06 21.5 Pfam 194-270 (270) Show / Hide 
Range on Protein: 185-259
Range on HMM: 194-270/270
Sequence Identity: 32% (26 aa)

KADIYSFGVTVFALLT-GKLP-FKGKTPEEAIANI-INGKFTLRLVE--NQDIADLIFRCMHSNPEKRPNATELINHPAF
| |..||||. . ..| |. | ..| ..|| .. |  .|   .   |   ..| ||. .|.| .||.||  .|.  |  .
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR-MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase 81312.m00091.AA Pkinase_Tyr 13-29 29 0.119383 6.21 Pfam 1-17 (270) Show / Hide 
Range on Protein: 13-29
Range on HMM: 1-17/270
Sequence Identity: 29% (5 aa)

LKYLAQIGSGTYGSVYL
.. . ..|.| .|.||.
ITFGKKLGEGAFGEVYK
Kinase 81312.m00091.AA Pkinase_Tyr 132-156 26 2.705031 1.62 Pfam 141-166 (270) Show / Hide 
Range on Protein: 132-156
Range on HMM: 141-166/270
Sequence Identity: 26% (7 aa)

NIIIDGFGRAKLCDFGMSITQ-SDSN
|. ..  . .| ||||.. .  .|..
NCLVTENNVVKICDFGLARDIYNDDY