Gene 87363.m00213 (T.vaginalis)

87363.m00213

Species: T.vaginalis
Alias: TvagK0297, 87363.m00213
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
87363.m00213.AA Protein None 797 None Fasta, JSON
87363.m00213.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 87363.m00213.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87363.m00213.AA TKL 212-454 27 3.9e-78 265.9 In-house 1-364 (364) Show / Hide 
Range on Protein: 212-454
Range on HMM: 1-364/364
Sequence Identity: 27% (101 aa)

IGHGVSSVVYYGYDNRTK--------NEVAIKELKYP-----------------------ILSGPSLNQFQRELTVLATAR--HPRVLGFVGATETAP--
|| | ...|| |. . .         ..||.| .|                         .   .| ..|..|  ..   |  || .. |.|.    |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCIVTEWMGGGTLYNILHSPKPTNPTMLSICMYDIARGMQFLHSRH--------IVHRDLKSLNVLFDNKGL--------------AH
            .|||.|.. ||.|...||      . .... ..||||||..|||..        |.|||||| |.| |...               . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRW-ALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IGDFGFSRRE----DDKMTQ------------------SIGTPHWMAPELLATGSFYTNKV---------------DVYAYGIVLWEILTKQYPY--NLM
|.|||.||.     ....|.                   .||| |||||.|    .||.||               |||..||||||||| . ||  . .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

DPQQIV-------AQVLANDLRPEIP------------ENSPPRLASLIKKCWDRNPDARPSFDRIVSEL
.|...        ..|  . |||.||            .. ||....|...||| .|..||||..|...|
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 87363.m00213.AA TKL-Unique 208-454 33 2.1e-72 246.87 In-house 1-290 (290) Show / Hide 
Range on Protein: 208-454
Range on HMM: 1-290/290
Sequence Identity: 33% (98 aa)

KVKEIGHGVSSVVYYGYDNRTKNEVAIKELKYPILSGPSLN--Q-FQRELTVLATAR-HPRVLGFVGATE----TAP-YCIVTEWMGGGTLYNILH----
 .. || |....|| |  ...  .|||| ..   ....|.   | | .|.... . . || .. ..|..     ..| .|||.| . ||.||. ||    
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

------SPKPTNPTMLSICMYDIARGMQFLHSRH--IVHRDLKSLNVLFDNK-----GLAHIGDFGFSRRED--DKMTQS----------IGTPHWMAPE
      . .. |. .      |||.|| .||..   | ||||||.|.| ||.       . | |||.|.  .  .||| .          .|.. |||||
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

LLATG-SFYTNKVDVYAYGIVLWEILTKQY------PYNLMDPQQIVAQVLA--NDLRPEIPENSPPRLASLIKKCWDRNPDARPSFDRIVSEL
.|    . |..|.|||..|||||||.| .       ||  ||..|. . |      .||.||.. |...  ||..||...|. ||||| |...|
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 87363.m00213.AA Dicty4 231-456 38 2.1e-71 237.45 In-house 24-277 (277) Show / Hide 
Range on Protein: 231-456
Range on HMM: 24-277/277
Sequence Identity: 38% (99 aa)

EVAIKEL--KYPILSGPSLNQFQRELTVLATARHPRVLGFVGATET----AP--YCIVTEWMGGGTLYNILHS------PKPTNP--TMLS---ICMYDI
|||.| |  .   ..   || | .| . ..  ||| .. | ||  |    .|   ||||| |  |.||..||.      .. . .  ....   ..  |.
EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGAC-TAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAF-DA

ARGMQFLHSRH--IVHRDLKSLNVLFDNKGLAHIGDFGFSR----RE--DDKMTQSIGTPHWMAPELLATGSFYTNKVDVYAYGIVLWEILTKQYPYN--
||||. ||..   |.|||||| | | |    . ..|||.|.     |   |...  .||| ||||| .. .  |. |.||| .|||||||||.| ||.  
ARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMM-HQPYNEKADVYSFGIVLWEILTRQEPYQKH

LMDPQQIVAQVLANDLRPEIPENSPPRLASLIKKCWDRNPDARPSFDRIVSE--LQQ
 |.. |.|. |    |||.|| . ||....||..||| .|  ||||  |...  |  
HMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 87363.m00213.AA MLK 206-454 32 5.2e-69 235.57 In-house 1-291 (291) Show / Hide 
Range on Protein: 206-454
Range on HMM: 1-291/291
Sequence Identity: 32% (96 aa)

LNKVKEIGHGVSSVVYYG-YDNRT--KNEVAIKELKYPI----LSGPSLNQFQRELTVLATARHPR----VLGFVGA-TETAP-YCIVTEWMGGGTLYNI
..  . ||.| . .|. | . |..    .||.|. .  |     .. .  .|..|   |.  .||     .  |.|. ... . .|||.|.. || |||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHSPKP--------------TNPTMLSICMYDIARGMQFLHSRH---IVHRDLKSLNVLFDN------KGLAHIGDFGFSRREDDK---MTQSIGTPHWM
||. ..                .  .   ....||||..|||     |.|||||| |.| |.      .| . | ||| ||   ..   |.  .||. ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APELL--ATGSFYTNKVDVYAYGIVLWEILTKQYPYN-LMDPQQIVAQVLANDLRPEIPENSPPRLASLIKKCWDRNPDARPSFDRIVSEL
||| .  . .. |. |.||. .|.||||.||.. ||   .|| .| ..| .| ||| || . |.....|.|.||. .|  ||||. ||..|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 87363.m00213.AA LRRK 206-456 25 3.5e-64 219.53 In-house 1-351 (351) Show / Hide 
Range on Protein: 206-456
Range on HMM: 1-351/351
Sequence Identity: 25% (89 aa)

LNKVKEIGHGVSS-VVYYGYDN--------------------------RTKNEVAIKELKYP--------------------------------ILSGPS
| . ..|| |..  .|| .  .                          .  ..|||| .. .                                . .  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LNQFQRELTVLATARHPRVLGFVGATETAPYCIVTEWMGGGTLYNILHSPK--------PT-NPTMLSICMYDIARGMQFLHSRH--IVHRDLKSLNVLF
.. |..|.... . .|| ..  .| .   |.|.|.| .  |.||  ||..|        .  .....   ...||.||..|||..  |.|||||| |.| 
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---D---------NKGLAHIGDFGFSR--REDDK--MTQSIGTPHWMAPELLATG--SFYTNKVDVYAYGIVLWEILTKQ-YPYNLMD-P-----QQIVA
   .         .   |.|.||| ||    . .     . |.| ||||| .  .  . || |||.|..|..|||.|| |  |.  .| .     . .. 
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

QVLANDLRPEIPEN-SPP-----RLASLIKKCWDRNPDARPSFDRIVSELQQ
.   . ||| ||..  ||     .. .||..||. .|. ||.|  ||. | |
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 87363.m00213.AA S_TKc 206-452 25 6.6e-62 212.89 SMART 1-220 (231) Show / Hide 
Range on Protein: 206-452
Range on HMM: 1-220/231
Sequence Identity: 25% (65 aa)

LNKVKEIGHGVSSVVYYGYDNRTKNEVAIKELKYPILSGPSLNQFQRELTVLATARHPRVLGFVGATETAPYCIVTEWMGG--GTLYNILHSPKP-----
  ....||.|  ..|| .....|. .||||..|         ....||. .|   .|| .  . .. ..  ...|.| ..|  |.|. .... ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-TNPTMLSICMYDIARGMQFLHSRHIVHRDLKSLNVLFDNKGLAHIGDFGFSRREDDKMTQSIGTPHWMAPELLATGSFYTN-KVDVYAYGIVLWEILTK
  .. .    || |.......||..|.|||||  |.|.|.     |.|||..|.     |  .|||..||||.|     |.  |.|... |..|.| |. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

QYPYNLMDPQQIVAQVLANDLRPEIPENSPPRLASLIKKCWDRNPDARPSFDRIVS
. |.   ..|..  ...            .| . ..|.||....|. ||.   .  
YPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase 87363.m00213.AA Pkinase_Tyr 206-454 29 1.5e-61 209.11 Pfam 1-270 (270) Show / Hide 
Range on Protein: 206-454
Range on HMM: 1-270/270
Sequence Identity: 29% (81 aa)

LNKVKEIGHGVSSVVYYGYDN----RTKNEVAIKELKYPILSGPS--LNQFQRELTVLATA-RHPRVLGFVGATE--TAP--YCIVTEWMGGGTLYNILH
. . |..|.|   .|| |. .     || .||.| || .  . .   .  | ||. .. .  .|| .. ..|.      |  ..||.| | .| |.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SP-----KPTNPTMLSICMYDIARGMQFLHSRHIVHRDLKSLNVLFDNKGLAHIGDFGFSRRE-----D-DKMTQSIGTPHWMAPELLATGSFYTNKVDV
..     ..| ...|..| ..||.||..|.|....||||   |.| .... . |.||| .|          | . .     ||||| ...|  .| | ||
KHREDKQPLTMKDLLQMC-WQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDV

YAYGIVLWEILT-KQYP-YNLMDPQQIVAQVLANDLRPEIPENSPPRLASLIKKCWDRNPDARPSFDRIVSEL
...|...|||.|  . | |  |.........  .  | ..||| |. . .|.|.||. .|. ||.|  |...|
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 87363.m00213.AA Pkinase 206-454 24 9.8e-60 209.56 Pfam 1-293 (293) Show / Hide 
Range on Protein: 206-454
Range on HMM: 1-293/293
Sequence Identity: 24% (72 aa)

LNKVKEIGHGVSSVVYYGYDNRTKNEVAIKELKYPILSGPSLNQFQR--ELTVLATARHPRVLGFVGATE-TAPYCIVTEWMGGG----TLYNILH--SP
. ... || | ...|| ...  |  .||.|..|..  .   . .  |  |. ...  .|| .. . .. |    ...|.|...||     |. ...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KPT--NPTMLSICMYDIARGMQFLHSRHIVHRDLKSLNVLFDNKGLA----HIGDFGFS----RREDDKMTQSIGTPHWMAPELLATGSFYTNKVDVYAY
..    .  .  .|| |.||....||. |.|||||. |.|.||.|      .|.|||..       .  ||   |||..||||.. .|. |. |||....
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVLWEILTKQYPYNLM------DPQQIVAQVLANDLRPEIPENSP-------------------PRLASLIKKCWDRNPDARPSFDRIVSE--L
|..|.| |... |.         |..|......  .|. ..|. ..                   . . ..||.|....|  ||... |.    .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87363.m00213.AA DRK 231-456 37 1.3e-58 197.12 In-house 24-258 (258) Show / Hide 
Range on Protein: 231-456
Range on HMM: 24-258/258
Sequence Identity: 37% (89 aa)

EVAIKELKYPILS-GPSLNQFQRELTVLATARHPRVLGFVGA-TETAPYCIVTEWMGGGTLYNILHSPKPTN--PTMLSICMYDIARGMQFLHSRH--IV
.||.| |.         || |.|| ...   ||| .  | |. ..    ||..| |  | |||||| ..     | |... | |.|.|| .||..   |.
QVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQM-MFDCAKGMIYLHCCNPIII

HRDLKSLNVLFDNKGLAHIGDFGFSR----REDDKMTQ-SIGTPHWMAPELLATGSFYTNKVDVYAYGIVLWEILTKQYPYNLMDPQQIVAQVLANDLRP
|||||| | | |      . ||| |      .. | .   .||| | ||| |.    || | ||| ..|||||..| | ||  | . |.|  |    .||
HRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQR-YTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMRP

EIPENSPPRLASLIKKCWDRNPDARPSFDRIVSELQQ
 .|.. ||  . |.. ||. .|  |||.. ..  |  
PMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 87363.m00213.AA TK 206-454 16 3.5e-56 186.48 In-house 1-486 (486) Show / Hide 
Range on Protein: 206-454
Range on HMM: 1-486/486
Sequence Identity: 16% (79 aa)

LNKVKEIGHGVSS---VVYYG------YDNRTKN-------------------EVAIKELK--YPILSGPSLN-------------QFQRELTVLAT--A
.  .|..|.|      .|| |       .| ...                   .||.| ||   .  .   .              .. .|. ..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPRVLGFVG-ATET------------APYCIVTEWMGGGT----LYNILHSPKPTNPTMLSI-------------------------------------
.|| .. ..|  |.              |..||.|.| .|     | . |.. .|.  ....                                      
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------CMYDIARGMQFLHSR------HIVHRDLKSLNVLFDNKGL-----------AHIGDFG----
                                      ....||.||..|||.      ..|||||   |.| ....            . |.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----FSRRE----DDKMTQSIGTPH-------------------------WMAPELLATGSF--------YTNKVDVYAYGIVLWEILT--KQYPYNLMD
     .|.     |   ..| ||.                          ||||| |... |        .| | ||...|...|||.|  .. .|  |.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

P---------QQIVAQVLAN-------------DLRPEIPENSP--------------PRLASLIKKCWDRNPDARPSFDRIVSEL
          |... .. .               .|.. |.. |              . .. |...||...|. ||.|. ....|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 87363.m00213.AA Dicty5 232-458 36 1.9e-54 185.83 In-house 25-260 (260) Show / Hide 
Range on Protein: 232-458
Range on HMM: 25-260/260
Sequence Identity: 36% (87 aa)

VAIKELKYPILSGPSLNQFQRELTVLATAR--HPRVLGFVGA-TETAPY-CIVTEWMGGGTLYNILHSPKP------TNPTMLSICMYDIARGMQFLHSR
||||..      .  .| |.|| |..      || .  . || .    |  .|||    |.| | |   .         .. |.. . |||..|..||| 
VAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAI-DIAQSMRHLHSM

HIVHRDLKSLNVLFDNKGLAHIGDFGFSR--REDDKMTQSIGTPHWMAPELLATGSFYTNKVDVYAYGIVLWEILTKQYPYNLMDPQQIVAQVLANDLRP
 |.||||||.|.|      . | ||| ||      .||  .||. |||.||  .|  |..|.|||..||||||..|.  ||  .    |   |   . ||
NIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELF-NGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGE-RP

EIPENSPPRLASLIKKCWDRNPDARPSFDRIVSELQQGN
.||   |   . ||||||   |  ||||  |.  ...  
TIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 87363.m00213.AA TyrKc 206-454 26 4.8e-54 186.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 206-454
Range on HMM: 1-280/280
Sequence Identity: 26% (78 aa)

LNKVKEIGHGVSSVVYYGYDNRTKNEVAIKELKYPILSGPSLNQFQRELTVLATA--RHPRVLGFVGATET--------APYCIVTEWMGGGTLYNILHS
. . |..|.|   .|| |  .    .||.| ||        .  | ||. ..     .|| .. ..|.  .         |..||.| | .| | . |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PKP-TNPTMLSICMYDIARGMQFLHSRHIVHRDLKSLNVLFDNKGLAHIGDFGFSRREDDK-------MTQSI----GTP-----HWMAPELLATGSFYT
..|  ..  |   ...||.||..|||....||||   |.| .... . |.||| ||  .|.        . .     |.       ||||| .   . .|
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

NKVDVYAYGIVLWEILT--KQYPYNL---MDPQQIVAQVLANDLRPEIPEN--------SPPRLASLIKKCWDRNPDARPSFDRIVSEL
 | ||...|...|||.|  .| ...    | . | | . . .  |...|.|         |. . ...|.||...|. ||.|  |....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 87363.m00213.AA Dicty4-Unclassified 206-454 33 1.6e-53 181.7 In-house 1-263 (263) Show / Hide 
Range on Protein: 206-454
Range on HMM: 1-263/263
Sequence Identity: 33% (90 aa)

LNKVKEIGHGVSSVVYYGYDNRTKNEVAIKELKYPILSGP--SLNQFQRELTVLATARHPRVLGFVGATETAP------YCIVTEWMGGGTLYNILH---
.   ..|| |  | |. |  |    .||.| .     .     .  | .|  .|    ||  .   |.   .|      .|||.| |  |.|  . |   
IQIDQFIGKGHFSKVHKG--NWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSKP

SPKPTNPTMLS--ICMY--DIARGMQFLHSRHIVHRDLKSLNVLFDNKGLAHIGDFGFSRREDD--KMTQSIGTPHWMAPELLATGSFYTNKVDVYAYGI
| .     . .  |  |  |||.|||.||.| ..|||.|| |.| |    . |.||| ||  |    ||   ||| | .|| |   | |. | ||| |..
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHES-YNQKSDVYSYAM

VLWEILTKQYPYNLMD-PQQIVAQVLANDLRPEIPENSPPRLASLIKKCWDRNPDARPSFDRIVSEL
.|.| .|   ||     .  .   |    |||.||.| .. . .||| ||   |  ||... |.  |
MLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 87363.m00213.AA STE 206-446 18 2.1e-53 183.76 In-house 1-347 (359) Show / Hide 
Range on Protein: 206-446
Range on HMM: 1-347/359
Sequence Identity: 18% (66 aa)

LNKVKEIGHGVSSVVYYGYDN------RTKNE---------VAIKELKYPILS---------------GPSLNQFQRELTVLATAR--HPRVLGFVGATE
. ....||.| . .||.....      .|...         .|||....   .                  ..|...|. ..   .  || .  . |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TAP--------YCIVTEWMGGGTLYNILH---SPKPTNP-----------TMLSICMYDIARG-MQFLHSRHIVHRDLKSLNVLFDNKGLAHIGDFGFSR
            .|. |.|.||.|  |..   ... ...           . ...  ..| .| ...||| ||.|||.|. |.|.     . . |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

REDD-------------------KMTQSIGTPHWMAPELLATG-----SFYTNKVDVYAYGIVLWEILTKQYPYNLMDPQQIVAQVLAN-----------
. .|                   | .  .||| ||||| .  .     . |. |.|..  |....| .| ..|.  | | .   . . |           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DLRPEIPENSP-------------------PRLASLIKKCWDRNPDARPS
   .  | .|..                     | .   |.|| ...|. ||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT