Gene 95629.m00070 (T.vaginalis)

95629.m00070

Species: T.vaginalis
Alias: 95629.m00070, TvagK0740
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
95629.m00070.AA Protein None 438 None Fasta, JSON
95629.m00070.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 95629.m00070.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PBD 95629.m00070.AA PBD 10-44 21 0.067035 3.04 SMART 1-38 (38) Show / Hide 
Range on Protein: 10-44
Range on HMM: 1-38/38
Sequence Identity: 21% (8 aa)

ISLPI-DAKLHVHIT-LDT-NRVYHNIPRSMLPAFSRE
||.|  . |  ||.   |  . .....| .    ... 
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
PBD 95629.m00070.AA PBD 71-128 33 6.3e-11 40.91 Pfam 1-60 (60) Show / Hide 
Range on Protein: 71-128
Range on HMM: 1-60/60
Sequence Identity: 33% (20 aa)

SISRL-VDVEHVLHVTVDQEKG-FVGLPPELERAVKASGISHQDIIKNPENAVNVINFLN
 ||    ...|. ||. |.. | |.|.|||... ...|||| ..  .||. .. |  | .
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD 95629.m00070.AA PBD 72-106 28 2.7e-05 24.84 SMART 1-38 (38) Show / Hide 
Range on Protein: 72-106
Range on HMM: 1-38/38
Sequence Identity: 28% (11 aa)

ISRLV-DVEHVLHVT-VDQ-EKGFVGLPPELERAVKAS
||    ...|. ||  .|. . .|.|||..... .| .
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase 95629.m00070.AA STE20 162-410 43 3.8e-113 382.21 In-house 1-288 (288) Show / Hide 
Range on Protein: 162-410
Range on HMM: 1-288/288
Sequence Identity: 43% (124 aa)

LQDLTKIDEGSTCTVYHAEFQ--GKL----IAVKEMLLTDK----TEK-VLIDETRLMSTMHDPHIIEFYDAYRDG----DKLWILMELMDGGSLTNIAT
 ..| || .||...|| |     |..    .|.| | | ..     |.  .. | . |.  . |.|...|..|  .    |.|||.||...||||| | .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

FC-ECQ---------EPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTVQLSE----HND-KRRSIVGTPYWMAPELIQA----
.| .|.         |..||.  .|.| .|.|| |...|||||| || |||.|| ||.||||.  ||..     .. || ..||||||||||.||     
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-TPYNYSVDIWSLGILCRELAEGEPPYVSEPPMKALFLIV--SKGIPEISN--KKERSPEFLDFLSKCLERDPEKRPTAAELLEHPFI
  .|.| .||||||| . |.|||||||  ..||.|.|.|   ... |. ..  ..  |||| ||..|||..|||||||| .||.||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 95629.m00070.AA PAKA 163-410 42 2.3e-111 376.27 In-house 2-260 (260) Show / Hide 
Range on Protein: 163-410
Range on HMM: 2-260/260
Sequence Identity: 42% (111 aa)

QDLTKIDEGSTCTVYHAEFQGKL----IAVKEMLLTDKTEK-VLIDETRLMSTMHDPHIIEFYDAYRDGDKLWILMELMDGGSLTNIATFCE------CQ
. ..|| .|....|| |.  .      .|.| | . .   |  .| | ..| . . . |. ..|.|   |.||. || |.||.|| . | |.       .
KFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYMD

EPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTVQLSEHNDKRRSIVGTPYWMAPELIQATPYNYSVDIWSLGILCRELAEGEP
| .||.  .|.| .|... |.. |||||| || || .|| |||.|||. .||.. . || ..||||||||||.|.   |.. ||||||||...|..||||
EGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGEP

PYVSEPPMKALFLIVSKGIPEISNKKERSPEFLDFLSKCLERDPEKRPTAAELLEHPFI
|| .||| .|..|| ..|.|.| ..   |.|| |||.|||. |...|..| |||.|||.
PYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 95629.m00070.AA STE 162-410 30 1.7e-104 353.43 In-house 1-359 (359) Show / Hide 
Range on Protein: 162-410
Range on HMM: 1-359/359
Sequence Identity: 30% (110 aa)

LQDLTKIDEGSTCTVYHA-----------------EFQGKLIAVKEMLLTD------------------KTEKVLIDETRLMSTMH--DPHIIEFYDAYR
.... || .|.. ||| |                 . .|...|.|.| | .                  . .. .. | ..|. ..   |.|...|..| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DG-------DKLWILMELMDGGSLTNIAT-FCECQ--------------EPHIAFFAKEILLA-LKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTV
..       |.||| ||.||||||. |    ..|.              |. ||.....|| . |.|| |...|||||| .| ||     ||..|||   
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLSEHND----------------KRRSIVGTPYWMAPELIQA------TPYNYSVDIWSLGILCRELAEGEPPYVSEPPMKALFLIVSK-----------
||.....                || ..|||| ||||| ||        .|....||||||... |.|.|.||.  ..||.|.|.|  .           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GIPEISN-----------------KKERSPEFLDFLSKCLERDPEKRPTAAELLE--HPFI
    ..| . .                 ... |||| ||..|||..||.||||| .||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 95629.m00070.AA PAKB 162-410 46 2.1e-89 303.35 In-house 1-252 (252) Show / Hide 
Range on Protein: 162-410
Range on HMM: 1-252/252
Sequence Identity: 46% (118 aa)

LQDLTKIDEGSTCTVYHAEFQ--GKLIAVKEMLLTDKTEK-VLIDETRLMSTMHDPHIIEFYDAYRDGDKLWILMELMDGGSLTNIATFCECQEPHIAFF
|..  || |||| .|  |  .  |...||| | |        |  |   |   . | |.|.|. |  || ||..|| |.||.|| | |    .|. ||  
LDNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHTRMNEEQIATV

AKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTVQLSEHNDKRRSIVGTPYWMAPELIQATPYNYSVDIWSLGILCRELAEGEPPYVSEPP
 . .| || || .|  |||||| |  |||.|| ||  |||.  |.|.   ||.| ||||||||||.|   ||   ||||||||.  |. .||||| .|||
CRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPP

MKALFLIVSKGIPEISNKKERSPEFLDFLSKCLERDPEKRPTAAELLEHPFI
..|.  |  .  | ..|    ||.  .||...| |||..| ||.|||.|||.
LQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase 95629.m00070.AA YSK 204-410 43 1.2e-82 248.59 In-house 47-257 (257) Show / Hide 
Range on Protein: 204-410
Range on HMM: 47-257/257
Sequence Identity: 43% (93 aa)

ETRLMSTMHDPHIIEFYDAYRDGDKLWILMELMDGGSLTNIATF---CECQEPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYT
|    |    | |  .| .|  . |||| ||   |||.          . .|..||.  .|||..|.|| |..|||||||  | ||. .| ||..|||  
EIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVA

VQLSEHNDKRRSIVGTPYWMAPELIQA--TPYNYSVDIWSLGILCRELAEGEPPYVSEPPMKALFLIVSKGIPEISNKKERSPEFLDFLSKCLERDPEKR
 |. .   ||   ||||||||||.|.   . |.. .|||||||   |.| |||||    ||...|||...  |. . ... |  | .|   ||. |||.|
GQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLE-GRSYSKMFKEFVECCLNKDPEQR

PTAAELLEHPFI
|.| ||| | ||
PSAKELLKHKFI
Kinase 95629.m00070.AA S_TKc 162-410 31 1.8e-80 274.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 162-410
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

LQDLTKIDEGSTCTVYHAEFQG--KLIAVKEMLLTDKTEKVLIDETRLMSTMHDPHIIEFYDAYRDGDKLWILMELMDG--GSLTNIATFCEC-------
 . | || .|.  .|| .   .  .. |.|..       . .. | ....  | |.|. .||...| |.|.. ||..||  |.|  .   . .       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QEPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTVQLSEHNDKRRSIVGTPYWMAPELIQATPYNY-SVDIWSLGILCRELAEG
 | |..|....|..||.|. |.. ||||.| .| ||..  |.||.|||   ||       ....|||..||||..   .|.. ..|.||.|..  |.. |
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

EPPYVSEPPMKALFLIVSKGIPEISNKKERSPEFLDFLSKCLERDPEKRPTAAELLE-------HPFI
.||.     |...| ..             |||..||..|||..|||||||| |.|.       ||..
YPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95629.m00070.AA MST 181-410 41 3.2e-73 232.09 In-house 22-254 (254) Show / Hide 
Range on Protein: 181-410
Range on HMM: 22-254/254
Sequence Identity: 41% (97 aa)

FQGKLIAVKEMLLTDKTEKVLIDETRLMSTMHDPHIIEFYDAYR--DGDKLWILMELMDGGSLTNI--ATFCECQEPHIAFFAKEILLALKYLRSQNKIH
. ||. |.| .   .     .| | . |. .  ..|  .|. |.      .|| ||  ..||.  |  .|     |  ||   .  |. |.|| .  |||
QTGKIVAIKMVPV-NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIACILYDTLQGLQYLHDNKKIH

RDIKTDNALLTSDGHVKIADFGYTVQLSEHNDKRRSIVGTPYWMAPELIQATPYNYSVDIWSLGILCRELAEGEPPYVSEPPMKALFLIVSKGIPEISNK
||||  | ||  .|. | ||||   ||.. . || . .||||||||| ||   |.. .||||||| . |.|||.|||    || |.|.| .| .|  .. 
RDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDP

KERSPEFLDFLSKCLERDPEKRPTAAELLEHPFI
 . |.|| ||..||| ..||.|.|| .||.||||
EQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 95629.m00070.AA Pkinase 162-410 27 8.1e-68 236.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 162-410
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

LQDLTKIDEGSTCTVYHAEFQGK--LIAVKEMLLTDKTEKVLID-----ETRLMSTMHDPHIIEFYDAYRDGDKLWILMELMDGG----SLT------NI
.. . || .||  .||..  .|   . |||.. . .. .....      | ..|  .. |.|...||...|.|.... ||...||    .|       . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ATFCECQEPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHV----KIADFGYTVQL-SEHNDKRRSIVGTPYWMAPELIQ-ATPYNYSVDIWS
 .|   .| .. |....|| .|.|. |.. ||||.| .| |. ..||.    ||.|||   |.   .|    ...|||..||||.|. ...| ..||.||
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGILCRELAEGEPPYVSE----PPMKALFLIVSKGI--PEISNKKERS-------------------PEFLDFLSKCLERDPEKRPTAAELLEHPFI
.|... |.. |.||. ..    . .  ...|. ..   .. .  ...|                   .|..||...||..||.|||||...|.||..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95629.m00070.AA STE11 183-410 32 3.4e-63 216.25 In-house 24-303 (303) Show / Hide 
Range on Protein: 183-410
Range on HMM: 24-303/303
Sequence Identity: 32% (92 aa)

GKLIAVKEMLLTDKT---------EKV------LIDETRLMSTMHDPHIIEFYDAYR---DGDKLWILMELMDGGSLTNIAT--FCE--CQEPHIAFFAK
|.|.|||.. . . .          .       . .| .||.... ..|. .|.. .   . |.. | || . ||||  .    .     .|. | .. |
GELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRHKWGPMKFDEMVIRKYTK

EILLALKYLRSQNKIHRDIKTDNALLTSDGH-VKIADFGYTVQLSEHNDKRRS----------IVGTPY--------WMAPELIQATP---YNYSVDIWS
 || .|.|| |.. |||||| .| || |||. .|.||||  ..|.... .  .          . ||||        ||||| |  ..   |  ..||||
QILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRDGYGRKADIWS

LGILCRELAEGEPPYVSEP--PMKALFLIVSKGIPEISNKKERS------PEFLDFLSKCLERDPEKRPTAAELLEHPFI
||    | | | ||.      .| |.| |...  | .    . |      .|  |||..|.|.||.|||||..||.||||
LGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase 95629.m00070.AA SLK 204-410 40 8e-63 210.74 In-house 46-259 (259) Show / Hide 
Range on Protein: 204-410
Range on HMM: 46-259/259
Sequence Identity: 40% (86 aa)

ETRLMSTMHDPHIIEFYDAYRDGDKLWILMELMDGGSLTNIATFCE--CQEPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTV
|  ..|... |.|.. |.||   .|||...|  ||| . ||    |   .|. |.. .|... ||..| |.. ||||.|  | |.| ||.|..||||   
EIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSA

QLSEHNDKRRSIVGTPYWMAPELI-----QATPYNYSVDIWSLGILCRELAEGEPPYVSEPPMKALFLIVSKGIPEISNKKERSPEFLDFLSKCLERDPE
.. .. .|| . .|||||||||..     . .|| | .|||||||   |.|..|||.    ||. |. |     |.. .  . | || ||| |||..||.
KNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQ

KRPTAAELLEHPFI
.|.|.|.|..|...
NRWTTAQLMQHQWV
Kinase 95629.m00070.AA PAKL 226-410 45 1.6e-62 214.04 In-house 68-256 (256) Show / Hide 
Range on Protein: 226-410
Range on HMM: 68-256/256
Sequence Identity: 45% (86 aa)

G-DKLWILMELMDGGSLTNIATFCE--CQEPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTVQLSEHND-KRRSIVGTPYWMA
. ...||||.    ||   .   |.   .|  |..  .  |. | || |.| ||||||  | ||. |. |||||||   ||    |    ...|||||||
KLNHYWILMDYCSLGSINDMMESCCKTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMA

PELIQATPYNYSVDIWSLGILCRELAEGEPPYVSEPPMKALFLIVSKGIPEISNKKERSPEFLDFLSKCLERDPEKRPTAAELLEHPFI
|| |  ..||. .|||||||   |.|.|.||    |||.|.  |  .  |  || |  ||.| ||| .|.  |||||. . .|| ||||
PEIINKQNYNNKCDIWSLGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 95629.m00070.AA MKC 214-410 37 1.2e-61 211.14 In-house 61-260 (260) Show / Hide 
Range on Protein: 214-410
Range on HMM: 61-260/260
Sequence Identity: 37% (77 aa)

PHIIEFYDAYRDGD-KLWILMELMDGGSLTNIATF-CECQEPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTVQLSE-HNDKR
| |. .. .. ..|  .|. || |.|| |.. .      .|  ||. .||.| .| || ..| .|||.|  |   ..|| .|. |||  . .|.   . .
PNIVKYHCSHMKHDDEIWMVMEFMQGGTLEEASQNSHKFCESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFGLCIDVSHEKEEIH

RSIVGTPYWMAPELIQATPYNYSVDIWSLGILCRELAEGEPPYVSEPPMKALFLIVSKGIPE---ISNKKERSPEFLDFLSKCLERDPEKRPTAAELLEH
   .| |.||.|| ||  .. |..||||.||   |.| |.||.  . .||| |.  . |.        .   |..| |||..||. ||.||||| .|| |
--MCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMANGRPPHH-KSRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKH

PFI
|||
PFI
Kinase 95629.m00070.AA TyrKc 162-410 23 2.9e-21 77.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 162-410
Range on HMM: 1-280/280
Sequence Identity: 23% (66 aa)

LQDLTKIDEGSTCTVYHAEFQGKLIAVKEMLLTDKTEKVLIDETRLMSTM--HDPHIIEFYDAYRDG-------DKLWILMELMDGGSLTNIATFCE--C
.. . |. ||  ..||...      ||| .      .. ...| |.|.    | |.|. .| . ...       . |.|.||.|..|.| .    ..   
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

QEPHIAFFAKEILLALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFGYTVQLSEH-------NDKRRSI-VGTP-----YWMAPELIQATPYNYSVDIW
. ..   |.  |     || |.| ||||. . | |......|||.||| .  . ..         .| .   |.       ||||| |.   ..   |.|
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SLGILCRELAE-GEPPYVS-----EPPMKALFLIVSKGIPEISNKKE------RSPEFLDFLSKCLERDPEKRPTAAELLEHPFI
| |... |.   |..||        ..  .. .. . . ...    .       ..|  .  ..| ..|||.||| .|.  | ..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 95629.m00070.AA Pkinase_Tyr 319-410 30 2.2e-07 25.62 Pfam 180-270 (270) Show / Hide 
Range on Protein: 319-410
Range on HMM: 180-270/270
Sequence Identity: 30% (29 aa)

WMAPELIQATPYNYSVDIWSLGILCRELAE-GEPP-YVSEPPMKALFLIVSKGIPEISNKKER--SPEFLDFLSKCLERDPEKRPTAAELLEHPFI
||||| |.   ..   |.|| |.|. |.   || | |   ..   . .|  .|      .. .  ..|  | . .| . |||.||| .|.  | ..
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR---MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase 95629.m00070.AA Pkinase_Tyr 265-298 50 1.2e-05 19.74 Pfam 123-156 (270) Show / Hide 
Range on Protein: 265-298
Range on HMM: 123-156/270
Sequence Identity: 50% (17 aa)

ALKYLRSQNKIHRDIKTDNALLTSDGHVKIADFG
.. || |.| ||||. . | |.|....|||.|||
GMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 95629.m00070.AA Pkinase_Tyr 201-241 28 0.00035 14.79 Pfam 50-94 (270) Show / Hide 
Range on Protein: 201-241
Range on HMM: 50-94/270
Sequence Identity: 28% (13 aa)

LIDETRLMSTM-HDPHIIEFYDAYR-DGDK--LWILMELMDGGSL
.. | ..|... | |.|. .| .   .|.   ..| ||.| .|.|
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL