Gene 82775.m00070 (T.vaginalis)

82775.m00070

Species: T.vaginalis
Alias: TvagK0276, 82775.m00070
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
82775.m00070.AA Protein None 1065 None Fasta, JSON
82775.m00070.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 82775.m00070.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82775.m00070.AA TKL 223-470 25 9.3e-84 284.57 In-house 1-364 (364) Show / Hide 
Range on Protein: 223-470
Range on HMM: 1-364/364
Sequence Identity: 25% (94 aa)

IGVGGFGKVYRAIRISTS--------EILAVKELRSDR-----------------------ISTNSWSSLYAEVETMASVH--HKNVLELVGAHINEP--
|| ||||.||...   ..        .  ||| ..|.                          ..||     |.|.|      | |.. ..|. ...|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YRIITRFCPGRSLFDRLHRSTHEYKTLTGTELTI-IAHQVAQGMCYLHKLG--------IVHRDLKTLNILLYQDNT-----------
            . |.. .||| ||...||            .... .|...|.||.|||  .        |.|||||. |||. ...|           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---ACVADFGLSGMVKENQE--------------------LYGGVGTPHYTAPEVLMHM----------------KYGPNVDTYSYGVVLWEMLTKKLPY
   ....||||| .......                    ..  .||| . |||||. .                .| . .| ||.|.||||.|| ..||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

GDMNHMAIY---------EHVVTRGWRLTIP------------QDTPEPLKKLIQRCWSRDPNERPDFNEIERLF
 |...| ..         . |. .| |..||             |.|...|||.|.||. ||..|| |.||   .
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 82775.m00070.AA MLK 217-470 31 9.3e-70 238.06 In-house 1-291 (291) Show / Hide 
Range on Protein: 217-470
Range on HMM: 1-291/291
Sequence Identity: 31% (92 aa)

LQIENQIGVGGFGKVYRAIRISTS---EILAVKELRSDRISTNSWS-----SLYAEVETMASVHHKN----VLELVGAHINEPYR--IITRFCPGRSLFD
.|..  ||.|.||||...    .     |.|||. |.. .   | .      .  |..  . . |.|    . ...|. ...|.   |.. .|.| ||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

RLHRST-------HEYK---TLTGTELTIIAHQVAQGMCYLHKLG---IVHRDLKTLNILLYQ------DNTACVADFGLSGMVKENQE-LYGGVGTPHY
 ||  .       |. |   . .   .  .|.|.|.|| |||..    |.|||||  |||...      . |. ..|||.| .......   .  ||. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

TAPEVL---MHMKYGPNVDTYSYGVVLWEMLTKKLPYG-DMNHMAIYEHVVTRGWRLTIPQDTPEPLKKLIQRCWSRDPNERPDFNEIERLF
 ||||.    . ||   .| .|.|||||||||...||  ... |||   |.  | |..||.. ||..|||...||. ||..||.| .|   .
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 82775.m00070.AA Pkinase 217-470 25 2.2e-67 234.99 Pfam 1-293 (293) Show / Hide 
Range on Protein: 217-470
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

LQIENQIGVGGFGKVYRAIRISTSEILAVKELRSDRISTNSWSSLYA--EVETMASVHHKNVLELVGAHI--NEPYRIITRFCPGR----SLFDRLHRST
..|. .|| |.||.||......|..| |||... .... . . ..    |.. |....|.|...| ..    ...| ... .|.|     .|||....  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST--

HEYKTL--TGTELTIIAHQVAQGMCYLHKLGIVHRDLKTLNILLYQDNTA----CVADFGLSGM--VKENQELYGGVGTPHYTAPEVLM-HMKYGPNVDT
......  .  |.  .. |...|. |.|. ||.|||||  |||. ....     ...||||.       |. ... .|||.| ||||.. . .||| || 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSYGVVLWEMLTKKLPYGDM------NHMAIYEHVVTRGWRLTIPQDTP-------------------EPLKKLIQRCWSRDPNERPDFNEIERL--F
.|.|..|.|||....|. .       ..|.... .  . ..  .|.. .                   |..|..| .|. .||..|| . .|     |
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82775.m00070.AA S_TKc 217-476 25 7.4e-65 222.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 217-476
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

LQIENQIGVGGFGKVYRAIRISTSEILAVKELRSDRISTNSWSSLYAEVETMASVHHKNVLELVGAHINEPYRIITRFCPG--RSLFDRLHRSTHEY--K
 .| ..|| |.|||||... ..| .| |.|...          ... |.. . . ||.|.  | ..  .. . ... .|.|   .|||....  ..   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

TLTGTELTIIAHQVAQGMCYLHKLGIVHRDLKTLNILLYQDNTACVADFGLSGMVKENQELYGGVGTPHYTAPEVLMHMKYGP-NVDTYSYGVVLWEMLT
 ..  .   ...|..... |.|..||.|||||  |||| .  .  ..||||.  .      .  .|||.| |||||   .||.  .| .| |..|.|||.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KKLPYGDMNHMAIYEHVVTRGWRLTIPQDTPEPLKKLIQRCWSRDPNERPDFNEIER---LFDRHEVY
 . |.   ..........            ....| .|..|. .||..||   |. .   .   |.  
GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82775.m00070.AA TyrKc 217-470 26 9.2e-61 209.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 217-470
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

LQIENQIGVGGFGKVYRAIRISTSEILAVKELRSDRISTNSWSSLYAEVETMASV--HHKNVLELVGAHIN--------EPYRIITRFCPGRSLFDRLHR
.. . ..| | ||.||... .   .  ||| |..|         .. | . | ..  ||.|.. |.|. .         ||. |.. ..|. .| |.|..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

STHEYKTLTGTELTIIAHQVAQGMCYLHKLGIVHRDLKTLNILLYQDNTACVADFGLSGMVKEN------QELYG---GVGTP-----HYTAPEVLMHMK
. ..   |.  .|  ...|.|.|| |||. ...|||| . |.|.  ..|. ..|||||  ...       .. |    . |.        .|||.... |
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGPNVDTYSYGVVLWEMLTK-KLPYGD-----MNHMAIYEHVVTRGWRLTIPQD--------TPEPLKKLIQRCWSRDPNERPDFNEIERLF
. .  | .|.||..||..|  . || .     |.   ..|.| ... |. .|..         |. . .....|| .||..|| |.|| ..|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY-RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 82775.m00070.AA Pkinase_Tyr 217-470 28 3.6e-60 204.39 Pfam 1-270 (270) Show / Hide 
Range on Protein: 217-470
Range on HMM: 1-270/270
Sequence Identity: 28% (79 aa)

LQIENQIGVGGFGKVYRAIRI----STSEILAVKELRSDRISTNS---WSSLYAEVETMASV-HHKNVLELVGAHI--NEP--YRIITRFCPGRSLFDRL
...  ..| | ||.||...      .|    ||| |.    .. .   . .. .|...| .  ||.|.. |.|. .   ||  . |.. ..|. .| | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HRSTHEYKTLTGTELTIIAHQVAQGMCYLHKLGIVHRDLKTLNILLYQDNTACVADFGLSGMVKENQELY-----GGVGTPHYTAPEVLMHMKYGPNVDT
..  .. . ||  .|  ...|.|.|| ||.  ...|||| . |.|.  .|.. ..||||.  . .| . |     ||      .|||.....|.    | 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

YSYGVVLWEMLT-KKLP-YGDMNHMAIYEHVVTRGWRLTIPQDTPEPLKKLIQRCWSRDPNERPDFNEIERLF
.|.||..||..|  . | | .|    .||..  .| |. .|...|... .|...||  ||..|| | || . .
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 82775.m00070.AA TKL-Unique 219-469 31 1.8e-58 200.56 In-house 1-290 (290) Show / Hide 
Range on Protein: 219-469
Range on HMM: 1-290/290
Sequence Identity: 31% (91 aa)

IENQIGVGGFGKVYRAIRISTSEILAVKELR-SDRISTNSWSSLYAEVETMASVH-HKNVLELVGAHI----NEP-YRIITRFCPGRSLFDRLHR-----
. | || ||.|.||...    ... |.| .     .|  .   .. || .|   | |.|.. ..|. .     .| . |.. .||| || | ||.     
FWNKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-STHEYKTLTGTELTIIAHQVAQGMCYLHKLG--IVHRDLKTLNILLYQD-----NTACVADFGLSGMVK-ENQELYGG---------VGTPHYTAPEVL
    . ..|.      .|...||||.||| ..  | |||||..|.|. ..     . . ..|||||   . .|.. ...         .|.. . |||||
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

MH--MKYGPNVDTYSYGVVLWEMLTKKL------PYGDMNHMAIYEHVVT--RGWRLTIPQDTPEPLKKLIQRCWSRDPNERPDFNEI-ERL
.    .|   .| ||.|.||||..| |.      || .|.. ...| | .  .. |..||.. |. ...|||.|| .|| .|| |.|| .||
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 82775.m00070.AA TK 217-470 16 9.6e-58 191.8 In-house 1-486 (486) Show / Hide 
Range on Protein: 217-470
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

LQIENQIGVGGFG---KVYRAIRISTS-------------------------EILAVKELRSDRISTNSWSSL--------------YAEVETMAS---V
.......| | ||   .||... .. .                         .  ||| |...  ..     .               ||.. | .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHKNVLELVG-AHIN------------EPYRIITRFCPGRS----LFDRLHRSTHEYKT-----------------------------------------
||.|.. |.|  . .            ||. |.. ..|. .    | | |... .. ..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTGTELTIIAHQVAQGMCYLHKL------GIVHRDLKTLNILLYQDNT-----------ACVADFGLSG
                               ||  .|  ...|.|.|| |||..      ..||||| . |.|. ..|.           . .|||||| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----MVK-----ENQELYGGVGTPH-------------------------YTAPEVLM---------HMKYGPNVDTYSYGVVLWEMLT--KKLPYGDM
     . .     ..    .. ||.                          ..|||.|.         . |. .  | .|.||..||..|  .. .||.|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

NH---------MAIYEHVVTR-----------GWRLTIP--QDTP--------------EPLKKLIQRCWSRDPNERPDFNEIERLF
..           ..|....            | |.  |  .. |              | .  |.|.||..||..||.| .. . .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 82775.m00070.AA Dicty4 217-466 33 6.4e-57 188.44 In-house 1-269 (277) Show / Hide 
Range on Protein: 217-466
Range on HMM: 1-269/277
Sequence Identity: 33% (91 aa)

LQIENQIGVGGFGKVYRAIRISTSEILAVKELRSDRIS--TNSWSSLYAEVETMASVHHKNVLELVGAHI---NEP--YRIITRFCPGRSLFDRLHR---
..||. || |.||.||...   .  . ||| | .. .    |  ... .||. |..  | |.. . || .    .|    | | ..|  .|.  ||    
INIEQRIGKGSFGEVYKGTWRGK--EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

STHEYKTLTGTELTI---IAHQVAQGMCYLHK--LGIVHRDLKTLNILLYQDNTACVADFGLSG---MVKENQE-LYGGVGTPHYTAPEVLMHMKYGPNV
   . ..|  .  .    .|  .|.|| .||     |.|||||. |.|  ..... |.|||||     .....  . . .||| ..||||.||  |   .
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DTYSYGVVLWEMLTKKLPYG--DMNHMAIYEHVVTRGWRLTIPQDTPEPLKKLIQRCWSRDPNERPDFNEI
| ||.| ||||.||.. ||    |. | ... |.  . |. ||...| ..|.|||.||. ||. || |.||
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEI
Kinase 82775.m00070.AA CAMK 222-466 17 4.9e-51 162.29 In-house 1-419 (425) Show / Hide 
Range on Protein: 222-466
Range on HMM: 1-419/425
Sequence Identity: 17% (72 aa)

QIGVGGFGKVYRAIRISTS------------EILAVKELRSDRIS--------------------------TNSWSSLYAEVETMAS-------VHHKNV
..| |.||||...|...|             .  |.| .  ....                           ..  ... |.| | .       ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LELVGAHI------------NEP---------YRIIT---RFCPGR----SLFDRLHRSTHEY-----------KTLTGTELTIIAHQVAQGMCYLHKLG
. |  .              .           . ...    .|.|      |||.. . ....           . .|  |   . .|..... |.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKTLNILLYQD-----------------NTACVADFGLSGMVKE------------------------NQELYGGVGTPHYTA-PEVLMHMK---
|||||||  |||| ..                 |.  ..|||.. ....                        .| ..  .|||.| | ||||   .   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YGPNVDTYSYGVVLWEMLTKKLPYGDM-------------NHMAIYEHVVTRGWRLTIPQDTP----------------------EPLK
           ||| .|  | ||.|  ||. ..|. .              |   ..| . .  ..   |. .|                      .  |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

KLIQRCWSRDPNERPDFNEI
 ||...  .||..|.   ..
DLIRKMLQVDPEKRMTIEQC
Kinase 82775.m00070.AA LRRK 217-472 27 6.4e-51 175.48 In-house 1-351 (351) Show / Hide 
Range on Protein: 217-472
Range on HMM: 1-351/351
Sequence Identity: 27% (97 aa)

LQIENQIGVGGFG-KVYRAIRIS--------------------------TSEILAVKELRSD--------------------------------RISTNS
| ||.|||.|||| .||||. ..                           ..  |.| .  |                                . ....
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

WSSLYAEVETMASVHHKNVLELVGAHINEPYRIITRFCPGRSLFDRLH---RST-HEYK-TLTGTELTIIAHQVAQGMCYLHKLG--IVHRDLKTLNILL
 ...  ||  | . .| |.. |.|  |. |..... . |  .| ..||   ..  |  |  .. . .  || |.| || |||.    |.|||||. ||||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

------Y------QDNTACVADFGLSGMVKENQE--LYGGVGTPHYTAPEVLMHM---KYGPNVDTYSYGVVLWEMLTKK-LPYGDMN-H-----MAIYE
      .      .. .| .||||.|.| .  ..  . | ||.| . |||..  .    |  .||.||.|..||| || . .|.....       | . |
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

HVVTRGWRLTIPQD-TPE-----PLKKLIQRCWSRDPNERPDFNEIERLFDR
  ...| | ||||.  |.      ...||| ||. ||..|| |..|      
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 82775.m00070.AA STE 217-465 21 3.7e-50 172.96 In-house 1-350 (359) Show / Hide 
Range on Protein: 217-465
Range on HMM: 1-350/359
Sequence Identity: 21% (75 aa)

LQIENQIGVGGFGKVYRAIRI------STSEI---------LAVKELRSDRIST---------------NSWSSLYAEVETMASVH--HKNVLELVGAHI
...  .|| |.||.||.|...      .| |.          |.|... .. ..               . . ..  |...|   .  |.|. .  |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NEP--------YRIITRFCPGRSLFDRLHRSTHEYKTLT----------GTELTIIAHQVAQG-MCYLHKLGIVHRDLKTLNILLYQDNTACVADFGLSG
.|           |.  ...| || | ...     |.|.           ... .|..|. .| . |||...|.|||.|  ||||     .  .|||..|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

MVKEN-----------------QELYGGVGTPHYTAPEVLMHMK------YGPNVDTYSYGVVLWEMLTKKLPYGDMNHMAIYEHVVTR-----------
 . ..                 |. .  |||| . ||||.. ..      |.  .| .| | ...||.| | |. ||..|  . .  .            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GWRLTIPQDTP-------------------EPLKKLIQRCWSRDPNERPDFNE
   |   ..|...                    ...|  |..|  .|||.||. ..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 82775.m00070.AA HH498 217-470 31 7.1e-48 149.64 In-house 1-284 (284) Show / Hide 
Range on Protein: 217-470
Range on HMM: 1-284/284
Sequence Identity: 31% (90 aa)

LQIENQIGVGGFGKVYR-AIRISTSEILAVKELRSDRISTNSW------SSLYAEVETMASVHHKNVLELVGAHINEP--YRIITRFCPGRSLFDRL---
.    .|| | |||||.   |     | |||  |.  ..  |         .  ||  |    | .|   |.| ...|    |.| .| . ||| .|   
IEFHEKIGSGSFGKVYKGEWR---NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTI

-----------HRSTHEYKTLTGTELTIIAHQVAQGMCYLHK---LGIVHRDLKTLNILLYQDNTACVADFGLSGMVKENQE--LYGGVGTPHYTAPEVL
           |     |  .      .|.  ||.|| |||      |.||||   |||...|  | ||||| |  |..  .  .    | . . |||| 
PIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVF

M-HMKYGPNVDTYSYGVVLWEMLTKKLPYGDMNHMAIYEHVVTRGWRLTIPQD----TPEPLKKLIQRCWSRDPNERPDFNEIERLF
    ||   || .||. ..|||.| ..|. .    |    .  .  | .|||      | .   |||.||.  |..|||| .| .. 
SQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 82775.m00070.AA Dicty4-Unclassified 217-470 30 5e-46 155.62 In-house 1-263 (263) Show / Hide 
Range on Protein: 217-470
Range on HMM: 1-263/263
Sequence Identity: 30% (82 aa)

LQIENQIGVGGFGKVYRAIRISTSEILAVKELRSDRISTN--SWSSLYAEVETMASVHHKNVLELVGAHINEP------YRIITRFCPGRSLFDRLH-RS
.||   || | | ||.. .        ||| . . . .          .||| . |. | | . . |. || |      . |.. | .   ||   | . 
IQIDQFIGKGHFSKVHKGNWKGKD--VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIHSKP

THEYKTLTGTE--LTIIAHQVAQGMCYLHKLGIVHRDLKTLNILLYQDNTACVADFGLSGMVKENQELYGGVGTPHYTAPEVLMHMKYGPNVDTYSYGVV
    . .   .     .|  .|||| .||   ..|||.|  |||.  .. . .||||.|  .  |. .    |||  ..||.|||  |    | |||...
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWEMLTKKLPYGDMN-HMAIYEHVVTRGWRLTIPQDTPEPLKKLIQRCWSRDPNERPDFNEIERLF
|.|..|   || .    | .   |  .. |  ||   .  .||||  ||. ||| || .|.|    
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL