92406.m00150

Species: T.vaginalis
Alias: 92406.m00150, TvagK0931
External Links:
Annotation:

Classification

Group: STE
Family: STE7
Subfamily: MEK1

Sequence

Name Sequence Type Origin Length Description Download
92406.m00150.AA Protein None 332 None Fasta, JSON
92406.m00150.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of 92406.m00150.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 92406.m00150.AA S_TKc 39-294 32 9.4e-80 272.18 SMART 1-231 (231) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

LTFLDFVGKGAFSTVYRVKMNDTGEIYALKKIKYAETQEQLKVIVNEIDCMNTLRHPNVLRLYNVFYQSGAIHIIMPYING--LTLAEALKIMPIP----
 ..|. .|||||..||... ..||.|.|.|.||        . | .||...   .|||. .|| ||.  . ....| |..|   .| . .| .. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

--PEAQLGRISYLAVQGLHYLRKNAYIHRDLKPSNILLSLEGQVLIADFGLARQLTASSEQACSYVGTISYMAPERIKGKEYQF-KSDVWSLGIIIYQMA
  || .  .. |  ...| |. ..  |||||||.||||.   .. |.||||||||        ...||  ||||| .    | . |.|.||.|.|.| |.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

LGHFPLPKDPAQVTYWDILDFVDKEVRIELPDPYAPDFKAFLMKCLYPNPEQRSDVNELVN-------DPWI
 |  | |    |...  |.                |..| |..|||  .||.|  . |. .       .||.
CGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 92406.m00150.AA STE 39-294 25 1.8e-78 266.99 In-house 1-359 (359) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-359/359
Sequence Identity: 25% (95 aa)

LTFLDFVGKGAFSTVYRVKMND---------------TGEIYALKKIKYAETQ----------------EQLKVIVNEIDCMNTLR--HPNVLRLYNVFY
.......||||| |||. . ..               ||||.| |.... . .                |... | .||. |. ..  |||. . |  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QSG-------AIHIIMPYINGLTLAEALK---IMPIPP-----------EAQLGRISYLAVQG-LHYLRKNAYIHRDLKPSNILLSLEGQVLIADFGLAR
. |        ..|.| |..| .| . .|   ... |            | |...| .  ..| |.|| .. .||||.||.||||     | ..|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTAS----------------SEQACSYVGTISYMAPERIKG------KEYQFKSDVWSLGIIIYQMALGHFPLPK-DPA----QVT--Y-----WDILD
||| |                ...  . |||  .||||.|..      |.| .|.|.||||. |  || |. |. .  |     . .  |     .. | 
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-

FVDKEVRIELPDP-------------------YAPDFKAFLMKCLYPNPEQRSDVNELVN--DPWI
 . ..    |||.                   . |.|| |. |||  .|..| ....| .   |.|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 92406.m00150.AA Pkinase 39-294 27 2.6e-68 238.06 Pfam 1-293 (293) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

LTFLDFVGKGAFSTVYRVKMNDTGEIYALKKIKYAETQE-QLKVIVN--EIDCMNTLRHPNVLRLYNVFYQSGAIHIIMPYINGL----TLAEALK----
....  .|.|.|..||. .  .||.|.|.|.||. .. . ...  ..  ||  |. |.|||..||| .|. .. |...|.| .|      |.. ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

-IMPIPPEAQLGRISYLAVQGLHYLRKNAYIHRDLKPSNILLSLEGQV----LIADFGLARQL-TASSEQACSYVGTISYMAPERIK-GKEYQFKSDVWS
  .   .| .. .. |  ..|| |. ..  |||||||.|||.. .|..     |.|||||.|. . ... . ...||. ||||| |. |..|  |.|.||
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGIIIYQMALGHFPLPKDPAQVTYWDILDFVDKEVRIELPDPYA-----------------------PDFKAFLMKCLYPNPEQRSDVNELVNDPWI
.|.|.|.|..|..| | ..   .  | .  ...  . .|. ..                        ...| |. .|| ..|..|    .....||.
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 92406.m00150.AA STE7-Unclassified 39-294 31 3.8e-67 229.39 In-house 1-301 (301) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-301/301
Sequence Identity: 31% (96 aa)

LTFLDFVGKGAFSTVYRVKMND------TGEIYALKKIKYAET-QEQLKVIVNEIDCMNTLR-HPNVLRLYNVFYQSGA---IHIIMPYINGLTLA---E
|..|. .|.|.. ||. ..         .| |.|.|.|.  ..  |  | |. |.   .    ||.. . |  .|...    |||.| |  . .|    .
LERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPTMDNDNEFMKQILRELKTLHKCQPHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKID

ALKIM----PI----PPEAQLGRISYLAVQGLHYLRKNA-YIHRDLKPSNILLSLEGQVLIADFGLARQLTASSEQACSYVGTISYMAPERIKGK-----
 .| |    ||     || .||.| |   .||.|| . . .||||.||.|||.. .||| |.||| . || .. ..| . ||. .||.||||.|      
IYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLENTLDEAKTWVGCQMYMSPERIQGQMPHRP

EYQFKSDVWSLGIIIYQMALGHFPLP---------KDPAQ--VTYWDILDFVDKEVRIELPD-----PYAPDFKAFLMKCLYPNPEQRSDVNELVN-DPW
 | .|||.||||. |  .|.| .|..         . ...     |..|. ....   .|||      . ..|. |  ||.. .|. |.|. .| |  ||
SYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNEHPW

I
|
I

Kinase 92406.m00150.AA STE7 39-294 33 1.4e-59 204.22 In-house 1-288 (288) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-288/288
Sequence Identity: 33% (97 aa)

LTFLDFVGKGAFSTVYRVKMNDTGEIYALKKIKYAETQ-EQLKVIVNEIDCMNTLR-HPNVLRLYNVFYQSGA--IHIIMPYINGLTLAEALKIMPIP--
| ... .|.|.. .|| .    .| |.|.|.|..  .. |  | |. |.| ..    .|.. . |  ||. |   |.|.| |  | .|   .|..     
LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKVYR

-------PEAQLGRISYLAVQGLHYLRK-NAYIHRDLKPSNILLSLEGQVLIADFGLARQLTASSEQACSYVGTISYMAPERIKG--KEYQFKSDVWSLG
       ||  ||.|..  ..|||||..   .|||| ||||||.  .||| ..||| . ||. | ..| ..||. .||||||| |  . |  .|||||||
GIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDGNKQHYDVRSDVWSLG

III-YQMALGHFPLP--KD-------------PAQVTYWDILDFVDKE-VRIELPDPYAPDFKAFLMKCLYPNPEQRSDVNELVN-DPWI
| . ..||.| .|.|  ..             |.    .. |. . .|    .||  . |.|. |  |||. .|  | .  .| .  |.|
ITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPE-MAIFEQLTCIVNENPPPRLP-KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI

Kinase 92406.m00150.AA Ciliate-E2 39-294 20 2e-55 188.75 In-house 1-365 (365) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

LTFLDFVGKGAFSTVYRVKMNDTGEIYALK-----------------KIKYAETQ--EQLKVIVNEIDCMNTLR----------------HPNVLRLYNV
  |.   |.|.|..||..|   ... .|.|                 ||.. ...   |.. | .||. |....                |||....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--QSGAIHIIMPYINGLTLAEALKIMPIPP-----------EAQLGRISYLAVQ---------------GLHYLRKNA-YIHRDLKPSNILLSLEGQV
|.  .   | ..| |..| .| . .|....             | . ..|..  .|               .|.|| ..   ||||.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

LIADFGLARQLTASSE-------------------------------QACSYVGTISYMAPERIKGKE---------YQFKSDVWSLGIIIYQMALGHFP
 |.||||..... ...                               .. ...||  ||||| ..||.         | .|.|.||||.|.|.|  | .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

LPKDPAQVTYWDILDFVDKEVRIELP----------------DPYAPDFKAFLMK----CLYPNPEQRSD-VNELVNDPWI
            .    ......  |                .   .. | .. |    .|  .||.| .  ... | ||.
F-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 92406.m00150.AA TKL 45-282 20 2.9e-52 179.93 In-house 1-354 (364) Show / Hide
Range on Protein: 45-282
Range on HMM: 1-354/364
Sequence Identity: 20% (75 aa)

VGKGAFSTVYRVKMND--------TGEIYALKKIK--------------------------YAETQEQLKVIVNEIDCMNTLRHPNVLRLYNVFYQSGA-
.|.|.|..||. | .         ||.  | ||.|                            |..   . ...|| .|. |||||..... .  ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IHIIMPYINGLTLAEALKIMPIPPEAQLGRISYLAVQGLHYLRKNA--------YIHRDLKPSNILLSLEGQ--------------VL
            ..|.| |. | .| . |         |. |... . .|..||  .          ||||||..|||.   ..              . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IADFGLARQLTASSEQACSY-------------------VGTISYMAPERIKGK----------------EYQFKSDVWSLGIIIYQMALGHFPLPKDPA
|.||||.| .. |... ..                    .||. .|||| ..|.                ||  |.||.| ||... .. .  |  ..| 
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

QVTY------WDILDFVDKEVRIELP------------DPYAPDFKAFLMKCLYPNPEQR
   .      ...   .||  | ..|            ..  |..|  ...|  ..||.|
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKR

Kinase 92406.m00150.AA ULK 39-294 25 3.3e-52 179.75 In-house 1-329 (329) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-329/329
Sequence Identity: 25% (86 aa)

LTFLDFVGKGAFSTVYRVKMNDT----GEIYALKKIKYAETQEQLKV---------IVNEIDCMNTLR--------HPNVLRLYNVFYQSGA--IHIIMP
    .  |||.| .||. . ..|    .|..| |.|   . .....          . |||. | .|         |||. .|| .|. |    | ||| 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YINGLTLAEALKIMPIPPEAQLG---------RISYLA--VQGLHYLRKNAYIHRDLKPSNILLSLE------------GQVLIADFGLARQLTAS---S
| || .| . .|     || .            |...   ..|. .|.|. .||||.||.|||..              |.. |||||.|.... .    
YCNGGDLEQYIKKNKKLPEDT-EEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

EQACSYV------GTISYMAPERIK----GKEYQ-FKSDVWSLGIIIYQMALGHFPLPKDPAQVTY-WDILDFVDK---------EVRIELP-----DPY
......|      ||  ||||. ..    .|.|  .|.|.||||.|.|.|  |  |  .  .. .| . | . ...            .. |     .. 
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

APDFKAFLMKCLYPNPEQRSDVNELVNDPWI
 |..| .. ..|  ....| .  || | ||.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 92406.m00150.AA ULK 39-294 26 8.2e-52 178.45 In-house 1-324 (324) Show / Hide
Range on Protein: 39-294
Range on HMM: 1-324/324
Sequence Identity: 26% (87 aa)

LTFLDFVGKGAFS-TVYRVKMNDT---GEIYALKKIKYAETQEQLKV---------IVNEIDCMNTLR---HPN--VLRLYNVFYQSGA--IHIIMPYIN
    .  |||.|  .||. . ..|   ....| |.|   . ... .          . |||  | .|    |||  . .|| .|. |    | ||| | |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GLTLAEALKIMPIPPEAQLG---------RISYLA--VQGLHYLRKNAYIHRDLKPSNILLSL------------EGQVLIADFGLARQLTA--SSEQAC
| .| . .|     || .            |...   ..|. .|.|. .||||.||.|||..             .|.. |||||.|...     ..| |
GGDLEQYIKKNKKLPE-T-EEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMC

-SYV------GTISYMAPERIK----GKEYQ-FKSDVWSLGIIIYQMALGHFPLPKDPAQVTY-WDILDFVDK---------EVRIELPD-----PYAPD
 ..|      ||  ||||. ..    .|.|  .|.|.||||.|.|.|  |  |  .. .. .| . | . ...            |. |.     .  |.
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

FKAFLMKCLYPNPEQRSDVNELVNDPWI
.| .....|  ....| .  |. | ||.
CKDLIRRMLQYDEKDRISWEEIFNHPWF

Kinase 92406.m00150.AA STE20 39-235 32 1.7e-51 177.37 In-house 1-227 (288) Show / Hide
Range on Protein: 39-235
Range on HMM: 1-227/288
Sequence Identity: 32% (74 aa)

LTFLDFVGKGAFSTVYRVKMNDTGEI----YALKKIKYAETQ---EQLKVIVNEIDCMNTLRHPNVLRLYNVFYQS----GAIHIIMPYINGLTLAEALK
 ..|. .|.|.. .||..  ..|||.    .| ||... . .   .... |..||. |. ..|||. . |. .. .      . |.|.| .| .| ...|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

-IMPIP--------PEAQLGRISYLAVQGLHYLRKNAYIHRDLKPSNILLSLEGQVLIADFGLARQLTA----SSE-QACSYVGTISYMAPERIKG----
  |..          |.|   | . ..|||.|| .| .||||.|  ||||. .|.| .||||.. |||     .   .  . |||  .|||| |..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-KEYQFKSDVWSLGIIIYQMALGHFPL
 |.| .|.|.||||| .  || |. |.
DKGYDYKCDIWSLGITAIEMAEGEPPY

Kinase 92406.m00150.AA Ciliate-E2-Unclassified 40-294 21 8e-48 163.97 In-house 2-352 (352) Show / Hide
Range on Protein: 40-294
Range on HMM: 2-352/352
Sequence Identity: 21% (77 aa)

TFLDFVGKGAFSTVYRVKMNDTGEI----YALKKIKYA--ETQEQLKVIVNEIDCMNTLR-------------------HPNVLRLYNVFYQSGAIHIIM
...   |.|.|..||... ......    |. |...|.    ...   |.||.. || .                    ||...... .| .   | |.|
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

PYINGLTLAEALKIMP-----------------IPPEAQLG-----RISYLAVQGLHYLRKNA-YIHRDLKPSNILLSLEG---QVLIADFGLARQLTAS
 |..|..| . .|...                 | .| |       .. .  .||| || ..   ||||.||.|||.. .|   .. |.|||.....  .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------SEQACSYVGTISYM----APERIKGKEYQ----FKSDVWSLGIIIYQMALGHFPLP-KDPAQ---VTYW---------DILDFVD
               .. ... .||..||    ||| ..|..|     .|.|.||||.|.|.|  | .| . ..  |   ...           . .. .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KEVRIELPDP----YAPDFKA--FLM----KCLYPNPEQRSDVNELVNDPWI
|.. .   ..    .  ...|  |.     |.|  ||..| . ... | ||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 92406.m00150.AA NEK 45-229 30 9.6e-48 164.94 In-house 7-218 (286) Show / Hide
Range on Protein: 45-229
Range on HMM: 7-218/286
Sequence Identity: 30% (65 aa)

VGKGAFSTVYRVKMNDTGEI-----YALKKIKYAETQEQLKVI-V-NEIDCMNTLRHPNVLRLYNVFYQ--SGAIHIIMPYIN-GLTLAEA---LKIM--
.|.|.|..||.|.   .| .     |..|||.. . .|. |   . ||.     |.|||. . |. |.   .. ..|.| | . | .|..    .|    
IGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQ

---PIPPEAQLGRISYLAVQ---GLHYLRKN-----AYIHRDLKPSNILLSLEGQ----VLIADFGLARQLTASSEQACS-YVGTISYMAPERIKGKEYQ
   ... |     |    .|   .|.|. ..       .|||.||.|| |. ..     | | |||....|  ... |.. .|||  ||.|| ...| | 
KGKYFEEE----QIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYN

FKSDVWSLGIIIYQMA
.|||.|||| ..|.|.
NKSDIWSLGCVLYEMC

Kinase 92406.m00150.AA TyrKc 39-297 24 2.7e-17 57.04 SMART 1-280 (280) Show / Hide
Range on Protein: 39-297
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

LTFLDFVGKGAFSTVYRVKMNDTGEIYALKKIK-YAETQEQLKVIVNEIDCMNTL--RHPNVLRLYNVFYQS-------GAIHIIMPYINGLTLAEALKI
.|...  | ||| .||. ...   .  | |..| .|     .. . .|.  |  |  .|||..||| |  |.       . . |.| |  .  | . |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MPI-PPEAQLGRISYLAVQGLHYLRKNAYIHRDLKPSNILLSLEGQVLIADFGLARQLTAS-------SEQACSY--VGT----ISYMAPERIKGKEYQF
     . ..|  ... . .|  || .. .|||||   |.|.. ...| |.||||.| ..         .    .    |     |  |||| |. ... .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVWSLGIIIY-QMALGHFPLPK-----DPAQVTYWDILDFVDKEVRIELPDP--------YAPDFKAFLMKCLYPNPEQRSDVNELVNDPWIQKF
|||||| |. ..  . .|  | |       ..|    ... .|..  | . |.           ..      .|   .||.|   .|.     ...|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ----EVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF

Kinase 92406.m00150.AA Pkinase_Tyr 146-223 37 1.1e-10 36.77 Pfam 122-202 (270) Show / Hide
Range on Protein: 146-223
Range on HMM: 122-202/270
Sequence Identity: 37% (31 aa)

QGLHYLRKNAYIHRDLKPSNILLSLEGQVLIADFGLARQLTASSEQACSYVGT-----ISYMAPERIKGKEYQFKSDVWSLGI
.|. ||  . .|||||   |.|.. ...| |.|||||| .  . ..  .....     |  |||| |. ...  |||||| |.
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGV

Kinase 92406.m00150.AA Pkinase_Tyr 39-119 31 1.5e-08 29.54 Pfam 1-91 (270) Show / Hide
Range on Protein: 39-119
Range on HMM: 1-91/270
Sequence Identity: 31% (29 aa)

LTFLDFVGKGAFSTVYRVKMN----DTGEIYALKKIKYAETQEQ--LKVIVNEIDCMNTL-RHPNVLRLYNVFY-QSGA--IHIIMPYING
.||.   |.||| .||. ...    .|.   | |..|   ..||  ..   .|.  | .| .|||..||| | . |..   | |.|.|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH

Kinase 92406.m00150.AA STE20 265-294 40 2.4e-05 15.81 In-house 259-288 (288) Show / Hide
Range on Protein: 265-294
Range on HMM: 259-288/288
Sequence Identity: 40% (12 aa)

PDFKAFLMKCLYPNPEQRSDVNELVNDPWI
|.|. |. |||  .||.|  . .| . |.|
PEFHDFVDKCLQKDPEKRPTASQLLKHPFI

Kinase 92406.m00150.AA NEK 259-294 28 0.000106 12.93 In-house 249-286 (286) Show / Hide
Range on Protein: 259-294
Range on HMM: 249-286/286
Sequence Identity: 28% (11 aa)

LPDP--YAPDFKAFLMKCLYPNPEQRSDVNELVNDPWI
.|.   | .| . .. ..| ..|||| ..|.. ..| |
IPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI