Gene 86188.m00106 (T.vaginalis)

86188.m00106

Species: T.vaginalis
Alias: 86188.m00106, TvagK0188
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
86188.m00106.AA Protein None 310 None Fasta, JSON
86188.m00106.kin_dom Protein Kinase Domain None 245 None Fasta, JSON

Protein domain

Protein domains of 86188.m00106.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86188.m00106.AA S_TKc 14-258 29 4.2e-75 256.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-231/231
Sequence Identity: 29% (77 aa)

LVCNGVIAEGGFGIVFNVYSLQYQTYFALKKIPEQRFNEAEIECMKRLDHPNACNLYNYYRFNGFVYMLLEYCPS---DLYNLMKLHES------LEDDL
     .| .|.|| |. ..    . ..|.|.|.  .  . ||...|. .||| ..|| ...  ...|| .|||.    ||. ..| . .      .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LKKYCYEILVSIKACHDQNIAHSDIKPSNFLLDKYGRLKICDFGLAAMYEDENMRSKTFKGTMLFMAPEVLNKREYNPIKADIWSIGVAFYFLASNSYPF
 ..|.|.|.  .. ||...| | |.||.| |||.  ..||||||||. .       .|| ||  .||||||    |.. |.|.||.|. .| ...   ||
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPF

DAKDKQTLLYLLNSGIYHTHSIDNSHLRQVIEKCLKMNPNERATIDELLK-------MPYF
.  . |... ..            . ... |.|||...|..| |. |.|.       .|.|
P--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86188.m00106.AA Pkinase 14-258 27 6.4e-66 230.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

LVCNGVIAEGGFGIVFNVYSLQYQTYFALKKIPEQRFNE---------AEIECMKRLDHPNACNLYNYYRFNGFVYMLLEYCPS-----DLYNLMK--LH
... ..| .|.|| |.  .   ..  .|.|.|. .. ..         .||. ||||.||| . || ... .. .|| .|||.      ||. ...   |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ESL--EDDLLKKYCYEILVSIKACHDQNIAHSDIKPSNFLLDKYGRL----KICDFGLAAMY-EDENMRSKTFKGTMLFMAPEVLNKREYNPIKADIWSI
 ..  ... .|.|.|.||  .. ||...| | |.||.|.|.|. | .    ||||||||. . .  |   .|| ||  .|||||.....| . |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVAFYFLASNSYPFDAK------DKQTLLYLLNSGIYHTHSIDN---------------------SHLRQVIEKCLKMNPNERATIDELLKMPYF
|. .| ...   ||. .      |.. ....  ....| ..                        . ....|..||...|..| |....|. |.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86188.m00106.AA CAMK 19-258 19 8.7e-64 204.13 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-258
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

VIAEGGFGIVFNVYSLQYQ------------TYFALKKIP---------------------------------EQRFNEAEIECMKR-------LDHPNA
.. .|.||.|. ..  . .            . .| | |.                                  ... . |||.||.       ||||| 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CNLYNYYRFNGF-------------------VYMLL---EYCPS-----DLYNLMKLHES---------------LEDDLLKKYCYEILVSIKACHDQNI
..|| .|  . .                   .|| .   |||.      ||..  . |..               .. .  ..|   |.  .. ||..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHSDIKPSNFLLDKY-----------------GRLKICDFGLAAMYED-----------------------ENMRSKTFKGTMLFMA-PEVLNK------
.| |.|| | |||.                  . .||.|||.|.....                       |.   ||| ||  .|| |||||.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------REYNPIKADIWSIGVAFYFLASNSYPFDAK-------------DKQTLLYLLNSGIYH-THS----------------IDNS-------HLRQ
       ..| . |.|.||.||  |.. .  .||...             . . |.    .| |.  ..                | ..         ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

VIEKCLKMNPNERATIDELLKMPYF
 | |.|. .|..|.||.. |. | .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 86188.m00106.AA CAMKL 13-258 25 6.5e-59 186.57 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-258
Range on HMM: 1-297/297
Sequence Identity: 25% (78 aa)

GLVCNGVIAEGGFGIVFNVYSLQY-QTYFALKKIP-----EQRFNEA---------------EIECMKRLD---HPNACNLYNYYRFNGF------VYML
  ..  .. .|.|| |      .. ..  | | |      .  ....               ||..||.|.   ||| . ||  .    .      .|. 
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LEYCPSD---LYNLMKLH----ESLEDDLLKKYCYEILVSIKACHDQNIAHSDIKPSNFLLDKYG--RLKICDFGLAAMYED----ENMRSKTFKGTMLF
.|||..    |..  . |    .... .  ..|   |.  .. ||...|.| |||| | |||. |   .||.|||...||..    ..   ||| |.  .
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEVLNK--REYNPIKADIWSIGVAFYFLASNSYPFDAK--------DKQTLLYLLNSGIYH--THSIDNSHLRQVIEKCLKMNPNERATIDELLKMPY
||||....  ..|.  |.||||.||  |..    .|||.         .. .|.   ..| |.   ..     .|. | | |. ||..|.||..... | 
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase 86188.m00106.AA MARK 19-258 31 1.1e-46 150.66 In-house 6-262 (262) Show / Hide 
Range on Protein: 19-258
Range on HMM: 6-262/262
Sequence Identity: 31% (80 aa)

VIAEGGFGIVFNVYSLQYQTYFALKKIP---EQRFNE-----AEIECMKRLDHPNACNLYNYYR--FNGF-VYMLLEYCPS-DLYNLMKLH--ESLEDDL
.| .|... |  . .. ... .|.| ..    .....      ||| ||.|||||   |. .     ..  .|. .||... .||. .| |    |. ..
TIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEE

LKKYCYEILVSIKACHDQNIAHSDIKPSNFLLDKYG--RLKICDFGLAAMYEDENMRSKTFKGTMLFMAPEVLNKREYNPIKADIWSIGVAFYFLASNSY
 ....  |.  .. ||..||.| |||| | |.|. |    ||.|||...  . .... .|| ||  .||||...|..|.  |.|||| ||  ||. . ..
ARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIP-PGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYF

PFDAKD--KQTLLYLLNSGIYHTHSIDNSHLRQVIEKCLKMNPNERATIDELLKMPYF
|||...    .|    ..| |.  .    ..|. | . |. ||.||.||.|..| | .
PFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 86188.m00106.AA AGC 14-258 16 2.3e-45 114.06 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-395/395
Sequence Identity: 16% (66 aa)

LVCNGVIAEGGFGIVFNVYSL------QYQTYFALKKIP-----------EQRFNEAE------------IECMKRLD----------HPNACN-LYNYY
     || .|.|| |. |         . . |.|.|..            ... . .|             . .....          ||. .. |.  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RFNGF--VYMLLEYCP---------SDLYNLMKLHE-----SLEDDLLKKYCYE-------ILVSIKACHD-QNIAHSD-IKPSNFLLDKYGRLKICDFG
  .    .|...||.|          ..  .. |..     ... .  . |. |       |.  .   |. ..| | | .|| | |||. | .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAAMYEDEN--------------------------------------------------MRSKTFKG--TMLFMAPEVLNKREYNPIKADIWS--IGVAF
|. .  ...                                                   | .|| |  |  .||||.|    |..  .|.||   |. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

YFLASNSYPFDAK----------DKQTLLYLLNSGIYHTHSIDN----------------SHLRQVIEKCLKMNPNERAT----------IDELLKMPYF
| . .   || ..          ..  .  .  .|.|  .                    . ..  |.|.|. .|..| .          ..|. . |.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 86188.m00106.AA ULK 14-258 24 1.5e-44 154.31 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-324/324
Sequence Identity: 24% (79 aa)

LVCNGVIAEGGFG-IVFNVYSLQY---QTYFALKKIPEQRFNE---------------AEIECMKRLD---HPN--ACNLYNYYRFN--GFVYMLLEYCP
 . | .. .| ||  |.  .  .    . |.| |.|. . .|.                ||. || |.   |||   . || ...     ..|. .|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

S-DLYNLMK---------LHESLEDDLLKKYCYEILVSIKACHDQNIAHSDIKPSNFLLDKY------------GRLKICDFGLAAMYEDEN---MRSKT
  || ...|          .  |. .  ..... |.   |. |..|| | ||||.| |. .             |.|||.|||.| . ...|   .  .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FK------GTMLFMAPEVLN----KREYNPIKADIWSIGVAFYFLASNSYPFDAKDKQTLL----YLLNSG------IYHTHSIDN---------SHLRQ
..      || |.|||..|.    . .|. .|.||||.|. || .  ..||| .  ....      |.| |      |. .    .         . ...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VIEKCLKMNPNERATIDELLKMPYF
 | ..|. ....| ...|....| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 86188.m00106.AA ULK 14-258 23 1.6e-44 153.35 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-329/329
Sequence Identity: 23% (78 aa)

LVCNGVIAEGGFGIVFNVYSLQY----QTYFALKKIP---EQRFN------------EAEIECMKRLD--------HPNACNLYNYYRFNGF--VYMLLE
 . | .. .| || |.  .  .     . ..| |.|.   ....|            . ||. ||.|.        ||| . || ...   .  .|. .|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPS-DLYNLMK----------LHESLEDDLLKKYCYEILVSIKACHDQNIAHSDIKPSNFLLDKY------------GRLKICDFGLAAMYEDEN----
||.  || ...|           .  |. .  ..... ||   |. |..|| | ||||.| |...             |.|||.|||.| . ...|    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-MRSKT----FKGTMLFMAPEVLN----KREYNPIKADIWSIGVAFYFLASNSYPFDAKDKQTLL-----YLLNSGIYH-----THSID----------N
 | . .    ..|| |.|||..|.    . .|.  |.||||.|. || .  . .|| |  ....       |.| .  .     .. ..           
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SHLRQVIEKCLKMNPNERATIDELLKMPYF
. ... | ..|. ....| ...||...| |
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 86188.m00106.AA Ciliate-E2 14-258 19 2.1e-44 150.36 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-365/365
Sequence Identity: 19% (74 aa)

LVCNGVIAEGGFGIVFNVYS-LQYQTY----------------------FALKKI----PEQRFNEAEIE--------------CMKRLDHPNACNLYNY
   . .| .|.||.|. .   .. . .                      .|.| .     || ..|  |                ...|.||| ...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YR--FNGFVYMLLEYCPS-DLYNLMK------LHE-----SLEDDLLKKYCYEILV---------------SIKACHDQN-IAHSDIKPSNFLLDKYGRL
.    .  .|. .|||   ||. ..|      .||     .. .   |.. ..||                 .. .| .| | | ||||.| |.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KICDFGLAA----------------MYEDEN----------------MRSKTFKGTMLFMAPEVLNKREY--------NPIKADIWSIGVAFYFLASNSY
||.||||.                 .| . .                .  .|. ||  .||||.||. .|           |.||||.|| .|.. .. .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDAKDKQTLLYLLNSGIYHTHSIDNSHLR--------------------------QVIEK----CLKMNPNERAT-IDELLKMPYF
||                .  .   .  ..                          . | |    .|. .|..| | ....|. |.|
PF----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86188.m00106.AA STE 14-258 19 4.6e-44 152.7 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

LVCNGVIAEGGFGIVFNVYSLQ---------------YQTYFALKKIP----------------------EQRFNEAEIECMKRLD--HPNACNLYNYYR
. . ..| .|.|| |.  .                   ....| |...                      |.   . ||. ||...  |||  . | .| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FNG-------FVYMLLEYCP-SDLYNLMK-LHESLE-------------DDLLKKYCYEILVS-IKACHDQNIAHSDIKPSNFLLDKYGRLKICDFGLAA
 .|        ... .||..   |  ..|  .. ..              ......|..||    .  |...| | ||||.| ||      |.||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

MYEDENM----------------RSKTFKGTMLFMAPEVLNK------REYNPIKADIWSIGVAFYFLASNSYPF-DAKDKQTLLYLLNSGI--------
  .|..                 ...|| ||  .|||||...       .|. .|.||||.|     .|   .|. | .. . ... .....        
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----YHTHSIDN----------------------SHLRQVIEKCLKMNPNERATIDELLK--MPYF
     .  .. .                      ..... |.|||...||.|.| ..|||   | .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 86188.m00106.AA Ciliate-E2-Unclassified 17-258 23 1.2e-39 135.15 In-house 4-352 (352) Show / Hide 
Range on Protein: 17-258
Range on HMM: 4-352/352
Sequence Identity: 23% (81 aa)

NGVIAEGGFGIVFNVYS-LQYQTYFALKKIP-------------EQRFNEAEIECMKR----------------LDHPNACNLYNYYRF--NGFVYMLLE
. .| .||||.|. ..   |.  |.|.| .              . ...  ..| ...                |.||. . .. .| |     .|. .|
IKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVME

YCPS------------------DLYNLMKLHESLEDDLLK-----KYCYEILVSIKACHDQN-IAHSDIKPSNFLLDKYG---RLKICDFGLAAMYEDE-
||.                   ||.. ||  . ...   |     .|...||. .. .| .| | | ||||.| |.|. |   ..||.|||..  |..  
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

--------------NMRSKTFKGTMLFM----APEVLNKREYNP---IKADIWSIGVAFYFLASNSYPFDAKDKQT----------------LLYLLNSG
              .....|| ||  .|    ||||| . .|.    .|.|||| || .|..  . |||.....                  |.   . .
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQK

IYHTHSIDN----SHLR--------QVIEKCLKMNPNERATIDELLKMPYF
..   . ..     |.         . . |.|| |||.| |....|. |.|
NIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86188.m00106.AA CMGC 14-150 20 3.5e-31 99.0 In-house 1-251 (513) Show / Hide 
Range on Protein: 14-150
Range on HMM: 1-251/513
Sequence Identity: 20% (52 aa)

LVCNGVIAEGGFGIVFNVYS--------------LQYQTYFALKKIPEQRFNE-----------------AEIECMKRL-----------------DHPN
  . ..| || .|.|.  .                ... . |.||| ..  .|                  ||...|.|                 .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ACNLYNYYRFNG-----------------FVYMLLEYCPSDLYNLMKLHE---------SLEDDL------------LKKYC------YEILVSIK--AC
  .||.......                  .|.  ||.. |||...| .           |..               |..       | || ..|   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HDQN--IAHSDIKPSNFLLD--------------------KYGRLKICDFGLA
| ..  | | |.||.| |..                    | |||||||||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase 86188.m00106.AA TyrKc 14-258 23 2.1e-12 -22.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-258
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

LVCNGVIAEGGFGIVFN-VYSLQYQTYFALKKIPEQRFNEA---EIECMKRL--DHPNACNLYNYYRFN-------GFVYMLLEYCPS-DLYNLMKLHES
.. . .. || ||.|.  ...    .  | |.. |    |.   |.. |..|  .|||  .|| . .         . .....||.|  || .  . |. 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LEDDLLKKYCYEILVSIKACHDQNIAHSDIKPSNFLLDKYGRLKICDFGLA-AMYED-------ENMRSKTFKGTM--L---FMAPEVLNKREYNPIKA
 |  . | ..|. |       |..|. | |.   | |... .. ||.||||. . |.|       .  |.|. ||.   |    ||||..|..... .| 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DIWSIGVAFYFLASN-SYPFDA-----KDKQTLLYLLNSGIYHTHSID---------NSHLRQVIEKCLKMNPNERATIDELLKMPYF
|.|| ||  . . ..   |        .. | .. .. .| .     .          . . |....| . .|..| |  |.    .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 86188.m00106.AA CMGC 172-258 14 5.6e-11 31.36 In-house 394-513 (513) Show / Hide 
Range on Protein: 172-258
Range on HMM: 394-513/513
Sequence Identity: 14% (18 aa)

PEVLNKREYNP--------IKADIWSIGVAFYFLASNSYPFDAKDKQTLLYLLNSG--------------------------IYHTHSIDNSHLRQVIEK
|..... .||.        .. ..||...  |.   |..|   . . . |.  ..                           .   .. ... ..  ..|
PNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQ-FKRKCCDPQAIDLLKK

CLKMNPNERATIDELLKMPYF
.|...|..| |... |..|||
MLQYDPDKRITAEQALQHPYF