TVAG_216840

Species: T.vaginalis
Alias: TvagK1058, TVAG_216840
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
TVAG_216840.AA Protein None 278 None Fasta, JSON
TVAG_216840.kin_dom Protein Kinase Domain None 199 None Fasta, JSON

Protein domain

Protein domains of TVAG_216840.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TVAG_216840.AA Ciliate-E2-Unclassified 17-191 16 2.5e-15 49.67 In-house 89-340 (352) Show / Hide
Range on Protein: 17-191
Range on HMM: 89-340/352
Sequence Identity: 16% (41 aa)

EFSNNELLYLITEDYTALNLKEYVATN-----------------GRLSDTEVL-----RISKSIADALTIMHMQH-VAHGGLDSRAICFDFSM---IPKL
.| . . .|...|    ..|..|   .                  .... ...     .. . | ..|  .| .. . |  .    | || ..    .|.
CFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI

SYFDFA----------------CDINIRKIEKVEVNIMNYF----PPEFLQF-NSNNQ--FTKDAWCLGIITYFMICAQYPFISANQIK-----------
. | ..                 .|..... .  .   ||     .|| ||  | ...  .  | |.||.| |.|.  .||| . |...           
IDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINN

-----LVNIIIKCQYMLPPTTH----PTIH--------ALIAKTLVQDPSQR
     | ..|.....  |.  .     ...         |. | |. .|..|
AYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR

Kinase TVAG_216840.AA SNRK 114-203 33 1e-13 41.0 In-house 165-254 (254) Show / Hide
Range on Protein: 114-203
Range on HMM: 165-254/254
Sequence Identity: 33% (30 aa)

YFPPEFLQFNSNNQFTKDAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRANARYISMMLRS
|  || |   |      | | ||.| | ..| | ||  ||    .  |. |.| .|.      . ||.. ||.|| .||    |      
YSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFQEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV

Kinase TVAG_216840.AA CAMKL 131-197 28 5.5e-13 37.62 In-house 218-291 (297) Show / Hide
Range on Protein: 131-197
Range on HMM: 218-291/297
Sequence Identity: 28% (22 aa)

DAWCLGIITYFMICAQYPFISA--------NQIKLVNIIIKCQYMLPPTTHP-TIHALIAKTLVQDPSQRANARYI
| | .|.| |.|.| ..||  .        |. .| ..|... |. |.  |.   . || | |. .|..|...  |
DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQI

Kinase TVAG_216840.AA MARK 131-194 28 9.2e-11 31.59 In-house 188-253 (262) Show / Hide
Range on Protein: 131-194
Range on HMM: 188-253/262
Sequence Identity: 28% (19 aa)

DAWCLGIITYFMICAQYPFISAN--QIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRANA
| | ||.. |||.| ..||  ..  . .|   | ...|  |.   . .. || . |. .|..|. .
DIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTI

Kinase TVAG_216840.AA CAMK 131-194 22 2.1e-10 28.98 In-house 316-416 (425) Show / Hide
Range on Protein: 131-194
Range on HMM: 316-416/425
Sequence Identity: 22% (23 aa)

DAWCLGIITYFMICAQYPFISA-------------NQIKLVNIIIKCQYMLPPTT--HPT----------------------IHALIAKTLVQDPSQRAN
| | .|.|.|.| |  .|| .              |. .|   |.|..|  ||    ...                         || | |. ||..|..
DMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMT

A
.
I

Kinase TVAG_216840.AA AMPK 131-193 33 1.2e-09 24.86 In-house 182-244 (254) Show / Hide
Range on Protein: 131-193
Range on HMM: 182-244/254
Sequence Identity: 33% (21 aa)

DAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRAN
| |  |.| | |.|.  ||   |. .|   |....| .|    | .. || . |  || .|..
DIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRIT

Kinase TVAG_216840.AA S_TKc 3-201 18 6.6e-08 -60.98 SMART 18-231 (231) Show / Hide
Range on Protein: 3-201
Range on HMM: 18-231/231
Sequence Identity: 18% (45 aa)

AVSKL-----------------------KHLNIAATIEFSNNELLYLITEDYTA--LNLKEYVATNGR------LSDTEVLRISKSIADALTIMHMQHVA
.. |                        .| ||   ...  .. ||...|       .|..|   .||      ..  .. .. . |..||  .| ... 
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII

HGGLDSRAICFDFSMIPKLSYFDFACDINIRKIEKVEVNIMNYFPPEFLQFNSNNQFTK---DAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYML
|  |    | .|     |.. | .|. .      .  .   .| .|| |      ...|   | | .|.| | |.| . ||   .. .. ..|       
HRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------

PPTTHPTIHALIAKTLVQDPSQRANARYISM---------ML
     |    .| | |. ||..|  |  .            .
----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase TVAG_216840.AA PLK1 113-203 27 1.1e-07 21.11 In-house 164-253 (253) Show / Hide
Range on Protein: 113-203
Range on HMM: 164-253/253
Sequence Identity: 27% (25 aa)

NYFPPEFLQFNSNNQFTKDAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRANARYISMMLRS
||  || |. .    |  | | .| | | ..  | || .         | |..|..|   ... . || | | .||..| ... .  .   
NYIAPEVLN-KKGHSFEVDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF

Kinase TVAG_216840.AA MELK 1-191 24 1.3e-07 21.74 In-house 48-242 (254) Show / Hide
Range on Protein: 1-191
Range on HMM: 48-242/254
Sequence Identity: 24% (47 aa)

MDAVSKLKHLNIAATIEF-SNNELLYLITEDYTALNLKEYVATNGRLSDTEVLRISKSIADALTIMHMQHVAHGGLDSRAICFDFSMIPKLSYFDFACDI
|||. .|.| .|     .   .. .... |  .  .. .|.  . ||.. |   . . |  |.  .| |  ||  |    . ||  .  ||  | .    
MDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT

NIRKIEK---VEVNIMNYFPPEFLQFNSNNQFTKDAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQR
  || .         . |  || .|  .      | | .||. | ..|   ||   |   .   |..  |  |.   |    |. . |  || .|
KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKR

Kinase TVAG_216840.AA AGC 133-191 20 2e-07 13.71 In-house 287-373 (395) Show / Hide
Range on Protein: 133-191
Range on HMM: 287-373/395
Sequence Identity: 20% (18 aa)

WC--LGIITYFMICAQYPFISAN----------QIKLVNIII------KCQYMLP----------PTTHPTIHALIAKTLVQDPSQR
|.  ||.. | |.. . || . |          . .. . |.      ...  .|          .   |    || | |. ||..|
WSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR

Kinase TVAG_216840.AA Pkinase 131-201 18 2e-06 23.65 Pfam 194-293 (293) Show / Hide
Range on Protein: 131-201
Range on HMM: 194-293/293
Sequence Identity: 18% (18 aa)

DAWCLGIITYFMICAQYPFISA------NQIKLVNIIIKCQYMLPPTTH---------------------PTIHALIAKTLVQDPSQRANARYISMM--L
| | .|.| | |.| . || ..      .|..... | ..... .  .                      ..   .| . | .||..| .|. |     .
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF





Kinase TVAG_216840.AA Ciliate-E2 131-191 27 2e-06 18.37 In-house 278-352 (365) Show / Hide
Range on Protein: 131-191
Range on HMM: 278-352/365
Sequence Identity: 27% (22 aa)

DAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQ-YMLPPTTHPT-----IH--------ALIAK----TLVQDPSQR
| |.||.| |.|.. ..||   .|||  .| . |. . .. |. .      ..         || |     |. ||..|
DIWSLGVILYEMLFGKPPF--QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR

Kinase TVAG_216840.AA Ciliate-E2 18-75 17 0.262802 0.22 In-house 101-187 (365) Show / Hide
Range on Protein: 18-75
Range on HMM: 101-187/365
Sequence Identity: 17% (15 aa)

FS--NNELLYLITEDYTALNLKEYVATN-----------GRLSDTEVLRISKSIAD---------------ALTIMHMQH-VAHGGL
|   ... .||..| .   .|..|   |           ..... |...|.| |..               ||  .| .. . |  .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI

Kinase TVAG_216840.AA Pkinase 6-72 19 3.250318 1.84 Pfam 56-131 (293) Show / Hide
Range on Protein: 6-72
Range on HMM: 56-131/293
Sequence Identity: 19% (15 aa)

KLKHLNIAATIEFS-NNELLYLITEDYTAL----NLKEYVA--TNGRL--SDTEVLRISKSIADALTIMHMQHVAH
.|.| ||  ....  ..  .|...|          |..|.    .|..  |. |. .. . |. .|  .| . . |
RLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH