Gene 97406.m00007 (T.vaginalis)

97406.m00007

Species: T.vaginalis
Alias: 97406.m00007, TvagK0902
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag3

Sequence

Name Sequence Type Origin Length Description Download
97406.m00007.AA Protein None 151 None Fasta, JSON
97406.m00007.kin_dom Protein Kinase Domain None 134 None Fasta, JSON

Protein domain

Protein domains of 97406.m00007.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97406.m00007.AA CAMK 11-139 21 2.2e-33 104.39 In-house 155-365 (425) Show / Hide 
Range on Protein: 11-139
Range on HMM: 155-365/425
Sequence Identity: 21% (45 aa)

IIKHGC---------------LSETLVKSLLPNVLVGLKDLHSNHIVHNDVKPENIVLCLD-----------------GKMKIIDFDLATIHDKEKCNY-
|..|||               ..|  .. .   .. ... .||..||| | ||||| |. .                 .. ||||| .|.. |. . |. 
IVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFM

---------------------EHGVFGTWPYMS-PEVVDG--------------GDHTEKVDVWSMGVVMYVALTGVLPFEAP-------------NQTT
                      . ..|| .||. |||. |                ...|.|.||.||..|. |.| .||...             |.  
CSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYE

YLDNVKQQPFN
 . ....  ..
LFEKIMKGKYD
Kinase 97406.m00007.AA Ciliate-E2-Unclassified 7-140 24 3e-31 105.64 In-house 107-305 (352) Show / Hide 
Range on Protein: 7-140
Range on HMM: 107-305/352
Sequence Identity: 24% (48 aa)

NLMDIIKH------------------GCLSETLVK-----SLLPNVLVGLKDLHSNH-IVHNDVKPENIVLCLDG---KMKIIDFDLATIHDKE------
.|...||.                   ...|  .|      ..  .|.||. ||... |.| | |||||..  .|   . ||||| ..   ..       
DLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTN

--------KCNYEHGVFGTWPYM----SPEVVDGGDHT----EKVDVWSMGVVMYVALTGVLPFEAPNQTT----------------YLDNVKQQPFNK
        | .  . . ||  ||    .||| .|  .     .|.|.||.||..|  |.| .||...|..                 ...| ||.....
QQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQF
Kinase 97406.m00007.AA CAMKL 3-139 27 7.2e-31 95.63 In-house 103-260 (297) Show / Hide 
Range on Protein: 3-139
Range on HMM: 103-260/297
Sequence Identity: 27% (44 aa)

AGKTN--LMDIIK-HGC----LSETLVKSLLPNVLVGLKDLHSNHIVHNDVKPENIVLCLDG--KMKIIDFDLATIHD---KEKCNYEHGVFGTWPYMSP
..  .  |.| |. ||.    ..|   . .   .. ... .||..||| | ||||| |  .|  . ||||| ......   . . .  .   |. |||.|
CSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAP

EVVDG---GDHTEKVDVWSMGVVMYVALTGVLPFEAP--------NQTTYLDNVKQQPFN
|.. |     .  |||.||.||..|. ..| |||...        |. ...  .... ..
EIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YY
Kinase 97406.m00007.AA Ciliate-E2 7-139 22 1.4e-30 102.18 In-house 120-306 (365) Show / Hide 
Range on Protein: 7-139
Range on HMM: 120-306/365
Sequence Identity: 22% (46 aa)

NLMDIIKHG------------CLSETLVKSLLPNVLV---------------GLKDLHSNH-IVHNDVKPENIVLCLDGKMKIIDFDLATIHDKE-----
.|.|.||.             ...|  .| .   .|                .|. |||.. |.| | |||||..      ||||| |... |..     
DLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRT

------KCNYEHG--------------------VFGTWPYMSPEVVDGGD---------HTEKVDVWSMGVVMYVALTGVLPFEAPNQTTYLDNVKQQPF
      .. . ..                    . || .||.||.. |..         ...|.|.||.||..|  |.| .||        ... ||...
HKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKI

N
.
D
Pkinase 97406.m00007.AA Pkinase 1-147 33 9.4e-30 106.29 Pfam 79-236 (293) Show / Hide 
Range on Protein: 1-147
Range on HMM: 79-236/293
Sequence Identity: 33% (55 aa)

MEAGKT-----NLMDIIK---HGCL--SETLVKSLLPNVLVGLKDLHSNHIVHNDVKPENIVLCLDGKM----KIIDFDLATIHDKEKCNYE-HGVFGTW
||          |.|.|.   |||.  ||  .|. .  .| ||. .||. |.| |.||||| .  .|      ||.|| ||  .|    |.. ... || 
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNSMTTFCGTP

PYMSPEVVD-GGDHTEKVDVWSMGVVMYVALTGVLPFEAPNQTTYLDNVKQQPFNKILLEKVH
.||.|||.  | ... |||.||.|...|  |.| .||   . ..   . ..| ...|.  ..|
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLH
Kinase 97406.m00007.AA RSK 13-128 33 9.9e-26 91.22 In-house 96-219 (278) Show / Hide 
Range on Protein: 13-128
Range on HMM: 96-219/278
Sequence Identity: 33% (41 aa)

KH-GCLSETLVKSLLPNVLVGLKDLHSNHIVHNDVKPENIVLCL---DGKMKIIDFDLATIHDKEKCNYEHGVFGTWPYMSPEVVD----GGDHTEKVDV
|| ||.||. ..  . .. . .. ||. .|.| | |||||..     .|  |..||... . . .. .  .   .|  || ||..     .| |.. .|.
KHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDW

WSMGVVMYVALTGVLPFEAPNQTT
|| ||.||  ||| .|| .||. .
WSLGVLMYEMLTGCPPFQGPNDNN
Kinase 97406.m00007.AA CAMK-Unique 15-125 26 2.6e-25 80.36 In-house 150-297 (363) Show / Hide 
Range on Protein: 15-125
Range on HMM: 150-297/363
Sequence Identity: 26% (39 aa)

GCLSE--TLVKSLLPNVLVGLKDLHSNHIVHNDVKPENIVLCLDGK----------------MKIIDFDLATIHD-KEKCNYEHGVFGTWPYMSP-----
| .||  ... ..   .|  .. .||. ||| | |.|||..|  .|                 |..||.|..  . ...|   . . || .||.|     
GHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFC

---------EVVDGGDHTEKV----DVWSMGVVMYVALTGVLPFEAPN
         ||... .  ...    | ||.||.||  |.| .||....
KNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCEC
Kinase 97406.m00007.AA Ciliate-E2b 11-121 31 3.5e-25 73.59 In-house 91-210 (272) Show / Hide 
Range on Protein: 11-121
Range on HMM: 91-210/272
Sequence Identity: 31% (38 aa)

IIKHG--CLSETLVKSLLPNVLVGLKDLHSNHIVHNDVKPENIVLCLDGKMKIIDFDLATIHDKEKC--NYEHGVFGTWPYMSPEVVD-----GGDHTEK
|.  |   ||.  ..     .. .|. ||.. |.. |.||||| .. .| ||.||. .| . .|..   .    . ||  || ||..      |   | |
IREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYK

VDVWSMGVVMYVALTGVLPF
||.||.|.. |  . | .|.
VDIWSVGICLYEFMCGYVPW
Kinase 97406.m00007.AA CDPK 37-139 32 2.8e-24 71.57 In-house 120-231 (271) Show / Hide 
Range on Protein: 37-139
Range on HMM: 120-231/271
Sequence Identity: 32% (37 aa)

HSNHIVHNDVKPENIVLCLDGKM-------KIIDFDLATIHDKE---KCNYEHGVFGTWPYMSPEVVDGGDHTEKVDVWSMGVVMYVALTGVLPFEAPNQ
||| ||| |.||||| .. . .        |.||...... |..     ..    .||  |..||| ..    ||.|.|| ||..|. | |. || . |.
HSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSCGVILYILLCGYPPFYGKND

TTYLDNVKQQPFN
   ...|| . ..
QEIMEKVKKGKYS
Kinase 97406.m00007.AA MARK 11-123 35 1.7e-22 70.53 In-house 93-208 (262) Show / Hide 
Range on Protein: 11-123
Range on HMM: 93-208/262
Sequence Identity: 35% (42 aa)

IIKH--GCLSETLVKSLLPNVLVGLKDLHSNHIVHNDVKPENIVLCLDG--KMKIIDFDLATIHDKEKCNYEHGVFGTWPYMSPEVVDGGDHT-EKVDVW
|..|  |.|.| . . .   .. ... .||..||| | ||||| .  .|  ..||||| .. |. .. .  .    || |||.||.. . . .  |||.|
IKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFS-ICIPPGQKLN-TFCGTPPYMAPEIFLKKPYDGPKVDIW

SMGVVMYVALTGVLPFEA
|.|||.|. ..| .||..
SLGVVLYFMVCGYFPFDG
Kinase 97406.m00007.AA MSK 33-121 34 8.4e-22 70.48 In-house 114-210 (277) Show / Hide 
Range on Protein: 33-121
Range on HMM: 114-210/277
Sequence Identity: 34% (33 aa)

LKDLHSNHIVHNDVKPENIVLCLD---GKMKIIDFDLATIHDKEKCNYEHGVFGTWPYMSPEVVDG-----GDHTEKVDVWSMGVVMYVALTGVLPF
.. .|. .|.| | ||||| .  .   |. |.||| .| .  ...    .   .|  ||.||....     | . | .|.||.||..|  |||  ||
VDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPF
S_TKc 97406.m00007.AA S_TKc 1-151 18 4.4e-10 -29.1 SMART 1-220 (231) Show / Hide 
Range on Protein: 1-151
Range on HMM: 1-220/231
Sequence Identity: 18% (45 aa)

MEAGKT--------------------------------------------------------------------NLMDIIKHGC-------LSETLVKSL
 | ...                                                                    .|.|.||.         ..|  ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

LPNVLVGLKDLHSNHIVHNDVKPENIVLCLDGKMKIIDFDLATIHDKEKCNYEHGVFGTWPYMSPEVVDGGDHTE-KVDVWSMGVVMYVALTGVLPFEAP
.  .. .|. .||..|.| |.||||| |.     ||.|| ||..         . . ||  ||.|||.    ..  |.|.|| |...|  |.|  ||.  
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--

NQTTYLDNVKQQPFNKI-----LLEKVHCSR------Q
.. . .....  .   .     .|.|    |      |
QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTAEALQ