Gene 94444.m00138 (T.vaginalis)

94444.m00138

Species: T.vaginalis
Alias: TvagK0786, 94444.m00138
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94444.m00138.AA Protein None 388 None Fasta, JSON
94444.m00138.kin_dom Protein Kinase Domain None 194 None Fasta, JSON

Protein domain

Protein domains of 94444.m00138.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94444.m00138.AA Ciliate-E2-Unclassified 125-207 27 3.8e-20 66.61 In-house 161-272 (352) Show / Hide 
Range on Protein: 125-207
Range on HMM: 161-272/352
Sequence Identity: 27% (31 aa)

KKK-VIHRDLKPQNIVIDGDL---VPHIIDWGDAT-------------TKLQNL---FTNNFHGTVSYA----APENFKGNKFLE-----SDMYSFGGIL
.|. .||||.||.||..| .     . |||.| .              .|.|..    .. | || .|     ||| ..|..  .     .|..|.| ||
HKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVIL

FFIVTQYQPYDQ
......| |...
YEMLFGYYPFYD
Kinase 94444.m00138.AA Ciliate-E2 98-262 15 1.1e-19 64.25 In-house 115-334 (365) Show / Hide 
Range on Protein: 98-262
Range on HMM: 115-334/365
Sequence Identity: 15% (39 aa)

YLQRDELSYLII-----------------LKILSTLAYQLL-------------------EMEKKK-VIHRDLKPQNIVIDGDLVPHIIDWGDATT----
|.|  .| ..|.                 .|  ... .|.|                   .. .|. .||||.||.||..     . |||.| ..     
YCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDD

-------KLQNLFTNNF----------------------HGTVSYAAPENFKGNKF----------LESDMYSFGGILFFIVTQYQPYDQAFDSLEGLKY
       ........ .                       ||  | |||...| |            ..|..|.| ||.. .. . |.            
NQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------

YTDQFPEMIFDLASIKEDFD-NLQIANTKEEKDMLQ-------DSLKNSISTI
              ...  . .... . . .|| .|       . .| | ...
--------------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECK
Kinase 94444.m00138.AA CAMK 125-206 21 3.4e-15 44.7 In-house 197-335 (425) Show / Hide 
Range on Protein: 125-206
Range on HMM: 197-335/425
Sequence Identity: 21% (30 aa)

KKKVIHRDLKPQNIVIDGD-----------------LVPHIIDWGDATTKLQ------------------------NLFTNNFHGTVSYAA-PENFKG--
.....|||||| || .| .                     |||.| |. . .                        .   . | || .|.| || ..|  
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

-----------NKF--LESDMYSFGGILFFIVTQYQPYD
           ..    ..|| | | ||.. .. | |..
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY
Kinase 94444.m00138.AA Ciliate-E3 98-199 28 5.1e-15 43.54 In-house 94-202 (202) Show / Hide 
Range on Protein: 98-199
Range on HMM: 94-202/202
Sequence Identity: 28% (31 aa)

YLQRDELSYLIILKILSTLAYQLLEMEKKKVIHRDLKPQNIVIDGDL---VPHIIDWGDATTKLQNL-FTNNF-HGTVS-YAAPE-NFKGNKFLESDMYS
|..  ...  ||..|   .   ...   |..|| |.||.|| .|  .   .  | | | .    .|.  |  .  |. . ||||| |....  .|||.||
YIKQQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPEQNDQQQISKESDYYS

FGGILFFIV
 | ..  ..
VGAVFCQLC
Kinase 94444.m00138.AA TKL 125-207 23 2.6e-14 47.95 In-house 158-291 (364) Show / Hide 
Range on Protein: 125-207
Range on HMM: 158-291/364
Sequence Identity: 23% (31 aa)

KKKVIHRDLKPQNIVIDGDLV--------------PHIIDWGDATTKLQNL--------------------FTNNFHGTVSYAAPENFKGNKFLES----
|...||||||..|| .| ..               . | | | .... |.                      |..  ||  . ||| ..|. ....    
KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGI

-------------DMYSFGGILFFIVTQYQPYDQ
             |.|||| .|. |.|  .||..
DEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD
S_TKc 94444.m00138.AA S_TKc 13-320 15 2.5e-13 18.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-320
Range on HMM: 1-231/231
Sequence Identity: 15% (51 aa)

IDHVFESATGGFGACKIVNIKD--KFLILKKLYAEDDTNGRSEFKNLTEIDLPFTPKVFDRAENHNESKWVLIDYIPG--LQLDEFIDLYLQRDE---LS
 . . .   |.|| .. .  |.  .   .|..      . |.| . | . . |.  | .|  ..  .. ..  .|..|    | ..|. .  .     ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

YLIILKILSTLAYQLLEMEKKKVIHRDLKPQNIVIDGDLVPHIIDWGDATTKLQNLFTNNFHGTVSYAAPENFKGNKFLESDMYSFGGILFFIVTQYQPY
   . ...  ..  |  . ....|||||||.|| .|   .  |.| | |.        . | ||  | ||| . |  . ..|..|.| ||.  .. | |.
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPF

DQAFDSLEGLKYYTDQFPEMIFDLASIKEDFDNLQIANTKEEKDMLQDSLKNSISTIVEILICNRITDNRLIEDFELLSDDFNFMIDNLIHRCWEYEYNK
.                ..|.|..                                                               ..| .|.... .|
P---------------QMQMMFKKIG--------------------------------------------------------SPEAKDFIRKCLQKDPEK

RISRSDLRDEI-----DKIA
|..  ..  .      .   
RPTA-EALQDEWDIKCHPWF
Kinase 94444.m00138.AA RIPK 126-205 31 3.6e-12 37.72 In-house 126-228 (290) Show / Hide 
Range on Protein: 126-205
Range on HMM: 126-228/290
Sequence Identity: 31% (32 aa)

KK--VIHRDLKPQNIVIDGDLVPHIIDWGDATTKLQNLFTNNFH--------------GTVSYAAPENFK-GNKFL------ESDMYSFGGILFFIVTQY
..  .|||||||.|| .|...   | | | || . .   ..  .              || || .||.|  .||        ..| |||. ... . || 
MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQK

QPY
.||
HPY
Kinase 94444.m00138.AA Dicty5 126-206 34 1.2e-11 36.39 In-house 123-204 (260) Show / Hide 
Range on Protein: 126-206
Range on HMM: 123-204/260
Sequence Identity: 34% (29 aa)

KKVIHRDLKPQNIVIDGDLVPHIIDWGDAT-TKLQNLFTNNFHGTVSYAAPENFKGNKFLES-DMYSFGGILFFIVTQYQPYD
. .||||||  |. |  ..   ||| |      ..  .| .  ||  . |.| |.|. . .  | |||| .|. . |.  |||
MNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHV-GTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYD
Kinase 94444.m00138.AA CAMKL 125-208 30 1.3e-11 33.18 In-house 145-239 (297) Show / Hide 
Range on Protein: 125-208
Range on HMM: 145-239/297
Sequence Identity: 30% (29 aa)

KKKVIHRDLKPQNIVIDGDL--VPHIIDWGDATTKL-Q----NLFTNNFHGTVSYAAPENFKG--NKFL--ESDMYSFGGILFFIVTQYQPYDQA
.....|||.|| || .| .   .  ||| | ..    .    . . . | |. .|.||| |.|   ..   . |. | | ||...|. | | |..
SHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDD
Kinase 94444.m00138.AA Pkinase 126-208 32 3.4e-11 40.68 Pfam 127-215 (293) Show / Hide 
Range on Protein: 126-208
Range on HMM: 127-215/293
Sequence Identity: 32% (30 aa)

KKVIHRDLKPQNIVIDGDLVP----HIIDWGDATT--KLQNLFTNNFHGTVSYAAPEN--FKGNKFLESDMYSFGGILFFIVTQYQPYDQA
...|||||||.|| || . ..    .|.|.| |       |  .. | ||  |.|||   .      ..||.|.| ||.  .. . |....
MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH
Kinase 94444.m00138.AA Ciliate-E2b 120-206 28 7.5e-11 29.37 In-house 115-211 (272) Show / Hide 
Range on Protein: 120-206
Range on HMM: 115-211/272
Sequence Identity: 28% (28 aa)

LLEMEKKKVIHRDLKPQNIVIDGDLVPHIIDWGDATTKLQNLF----TNNFHGTVSYAAPENFK----GNK--FLESDMYSFGGILFFIVTQYQPYD
| .  ....|.||.|| || .| .  . .|| | | .  ..      |    ||  | |||  .    |.|    ..|..|.| .|...   | |..
LEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPWA
Kinase 94444.m00138.AA MLK 122-213 29 1.3e-10 33.11 In-house 142-244 (291) Show / Hide 
Range on Protein: 122-213
Range on HMM: 142-244/291
Sequence Identity: 29% (31 aa)

EMEKKKVIHRDLKPQNIVID------GDLVPHIIDWGDATTKLQNL---FTNNFHGTVSYAAPENF---KGNKFLE-SDMYSFGGILFFIVTQYQPYDQA
.|..|..||||||..||.||      ....  | | ... .....     ..|  ||. . ||| .   ...|. | .|..|.| .|  ..|   ||.| 
SMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICD-FGTSRDWHQMCTNMMSNA-GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQH

FDSLE
 |...
YDPMA
TyrKc 94444.m00138.AA TyrKc 37-316 14 0.000208 -151.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 37-316
Range on HMM: 1-280/280
Sequence Identity: 14% (48 aa)

LILKKLYAE---------------------DDTNGRSEFKN----LTEI--D----LPFTPKVFDRAENHN---ESKWVLIDYIPGLQLDEFIDLYLQRD
. |.|   |                     .|.  | .| .    ....  .    . .   . .  .|     |  ...  | |.  |....  .  . 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

ELSYLIILKILSTLAYQLLE----MEKKKVIHRDLKPQNIVIDGDLVPHIIDWGDATTKLQN--------LFTN----NFH--GTVSYAAPENFKGNKF-
     . .| |   ..|  .     ..|..|||||   |. .. ...  | | | .                .     . .    .   ||| .. .|| 
-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

LESDMYSFGGILFFIVTQ-YQPYDQ-AF--DSLEGLKYYTDQF--PEMIFD---LASIKEDFDNLQIANTKEEKDMLQDSLKNSISTIVEILICNRITDN
 .|| .|||  .. | |   |||   ..   | . .  | .|   ..   .   ..                                            
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------------------

RLIEDFELLSDDFNFMIDNLIHRCWEYEYNKRISRSDLRDEI
     |         | . .. .||... ..| . |......
-----F---VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase 94444.m00138.AA RIPK 293-316 25 0.166045 0.86 In-house 267-290 (290) Show / Hide 
Range on Protein: 293-316
Range on HMM: 267-290/290
Sequence Identity: 25% (6 aa)

NLIHRCWEYEYNKRISRSDLRDEI
.|. |||... |.| .  . ....
ELMQRCWQQDPNDRPCFQECEEWT