Gene 85241.m00277 (T.vaginalis)

85241.m00277

Species: T.vaginalis
Alias: 85241.m00277, TvagK0175
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85241.m00277.AA Protein None 199 None Fasta, JSON
85241.m00277.kin_dom Protein Kinase Domain None 146 None Fasta, JSON

Protein domain

Protein domains of 85241.m00277.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85241.m00277.AA Ciliate-E2-Unclassified 2-146 25 1.8e-26 88.88 In-house 153-352 (352) Show / Hide 
Range on Protein: 2-146
Range on HMM: 153-352/352
Sequence Identity: 25% (51 aa)

IQTVKAVHDKK-VAHQEIKPTNFLVDFYG---KIKISDYGISSLYAKN---------------PMSESFNAQRNHY-----APEVFRSKSYDKM---QAD
.|  .  | |. . |  ||| | |.|  |   .|||.|.|||. | .|               ..  . ... . |     ||||.... ||..   ..|
LQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCD

IWSLGVTIFYFITGKYPFSSKDPNL----------------LIKKIMSG-VYMEGLIE-------DPQMKSLIA----DCLSINAPFRPTIDEILNNQVF
|||||| ......|.|||.... .                 |...|. . ..     .       .|. | .|      .|  |   |.|...||| . |
IWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85241.m00277.AA Ciliate-E2 1-146 20 6.4e-26 85.95 In-house 169-365 (365) Show / Hide 
Range on Protein: 1-146
Range on HMM: 169-365/365
Sequence Identity: 20% (44 aa)

MIQTVKAVHDKK-VAHQEIKPTNFLVDFYGKIKISDYGISSLYAKN-------PMSESFNAQR--------------------------NHYAPEVFRSK
.|. ..  | |. . |  ||| | |.     |||.| |.|  | ..       .... .   .                          .  |||....|
IILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGK

SYDK--------MQADIWSLGVTIFYFITGKYPFSSKDPNLLIKKIMSGVYM------------------EGLIEDPQMKSLIAD----CLSINAPFRPT
.||.         ..|||||||.......||.||        ...|. . .                   . .  ....| ||      .|  .   |.|
KYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT

-IDEILNNQVF
 ...|||.. |
GWEQILNHPWF
Kinase 85241.m00277.AA CAMK 9-146 18 2.5e-24 74.7 In-house 196-425 (425) Show / Hide 
Range on Protein: 9-146
Range on HMM: 196-425/425
Sequence Identity: 18% (43 aa)

HDKKVAHQEIKPTNFLVDFY-----------------GKIKISDYGISSLYAK------------------------NPMSESFNAQRNHYA-PEVFRS-
|.....|  .|| | |.|                   ..|||.| | .  . .                        ... . |       | |||... 
HSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

------------KSYDKMQADIWSLGVTIFYFITGKYPFSSK-------------DPNLLIKKIMSGVYM-EGLIEDP----------------------
            | |.  ..|.||.||  .   .|..|| ..             ... | .|||.| |  .    .|                      
GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

-QMKSLIADCLSINAPFRPTIDEILNNQVF
 . |.||  .|  .   |.||...|| . .
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85241.m00277.AA Pkinase 1-146 24 2.1e-22 80.33 Pfam 117-293 (293) Show / Hide 
Range on Protein: 1-146
Range on HMM: 117-293/293
Sequence Identity: 24% (43 aa)

MIQTVKAVHDKKVAHQEIKPTNFLVDFYGKI----KISDYGISSL--YAKNPMSESFNAQRNHYAPEVFRSKSYDKMQADIWSLGVTIFYFITGKYPFSS
... ..  |.... |  .|| |.|.|  | |    ||.| |.. .  | .|.   .|   ..  |||| |. .|.   .|.||.|........|. ||..
ILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPG

K------DPNLLIKKIMSGVYMEGLIED---------------------PQMKSLIADCLSINAPFRPTIDEILNNQVF
.      |.. .|..||.. ...   ..                     . .|..| .||  .   |||...||.   |
HCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85241.m00277.AA CAMKL 9-146 32 3.5e-21 64.23 In-house 144-297 (297) Show / Hide 
Range on Protein: 9-146
Range on HMM: 144-297/297
Sequence Identity: 32% (50 aa)

HDKKVAHQEIKPTNFLVDFYG--KIKISDYGISSLYAK-----NPMSESFNAQRNHYAPEVFRS--KSYDKMQADIWSLGVTIFYFITGKYPFSSKDPN-
|.....|  ||| | |.|  |  .|||.| | | .| .     . . . |    .  |||.| .  |.||  ..||||.||. .  ..|..||   . | 
HSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNK

------LLIKKIMSGVYMEGLIEDP-QMKSLIADCLSINAPFRPTIDEILNNQVF
      .| .|||.| |..    .. . ..||   |  |   ||||..|.|   .
QGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 85241.m00277.AA MELK 1-146 27 5.7e-17 54.23 In-house 106-254 (254) Show / Hide 
Range on Protein: 1-146
Range on HMM: 106-254/254
Sequence Identity: 27% (41 aa)

MIQTVKAVHDKKVAHQEIKPTNFLVDFYGKIKISDYGISSLYAKNPMSES----FNAQRNHYAPEVFRSKSYDKMQADIWSLGVTIFYFITGKYPFSSKD
..  .  || .  ||...|| |.|.| . ..|. |.|. .   |  . .             |||. . |.|    ||.||.|. ..  . |  ||    
IVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDN

PNLLIKKIMSGVYMEGLIEDPQMKSLIADCLSINAPFRPTIDEILNNQVF
  .. ||||||.| |     |. | |.   | ..   |  . ..|| .  
MMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 85241.m00277.AA QIK 3-107 32 2.8e-16 59.61 In-house 126-233 (272) Show / Hide 
Range on Protein: 3-107
Range on HMM: 126-233/272
Sequence Identity: 32% (35 aa)

QTVKAV---HDKKVAHQEIKPTNFLVDFYGKIKISDYGISSLYAKNPMSESFNAQRNHYAPEVFRSKSYDKMQADIWSLGVTIFYFITGKYPFSSKDPNL
|.. ||   |.....|  .|  | | |    ||| |.| | .. .  . ...       |||.|  |.|| ...||||.||  .  ..|. || .|  . 
QICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQN

LIKKIMSG
| ....||
LRQRVLSG
Kinase 85241.m00277.AA MARK 9-146 35 4.6e-16 49.17 In-house 121-262 (262) Show / Hide 
Range on Protein: 9-146
Range on HMM: 121-262/262
Sequence Identity: 35% (51 aa)

HDKKVAHQEIKPTNFLVDFYG--KIKISDYGISSLYAKNPMSESFNAQRNHYAPEVFRSKSYDKMQADIWSLGVTIFYFITGKYPFS--SKDPNLLIKKI
|.| ..|  ||| | |.|  |  .|||.| | |     . . ..|       |||.| .| ||   .|||||||  .. ..|..||   ..| . | |||
HSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKI

MSGVYMEGLIEDPQMKSLIADCLSINAPFRPTIDEILNNQVF
 .|.|       .. ..||   | .|   ||||.||..   .
LRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85241.m00277.AA GIN4 1-146 28 9e-16 46.45 In-house 143-293 (293) Show / Hide 
Range on Protein: 1-146
Range on HMM: 143-293/293
Sequence Identity: 28% (44 aa)

MIQTVKAVHDKKVAHQEIKPTNFLVDFYGK-IKISDYGISSLYAKNPMSESFNAQRNHYAPEVFRSKSYDKMQADIWSLGVTIFYFITGKYPFSSKDPNL
.|  |   |   . | ..|| | |.|   . ||| |.|.  |  .| . |         |||.     |.   .|.|| || .|  .||. ||   | |.
IIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNI

--LIKKIMSGVYMEGLIED----PQMKSLIADCLSINAPFRPTIDEILNNQVF
  |. |. .| |   . .|     . . ||.  | .    | .. .||   . 
RKLLLKVQKGKYE--MPSDDEISREAQDLIRKILVVDPEKRIKTRDILKHPLI
Kinase 85241.m00277.AA CAMKK 59-104 31 2.3e-13 38.32 In-house 278-341 (396) Show / Hide 
Range on Protein: 59-104
Range on HMM: 278-341/396
Sequence Identity: 31% (20 aa)

APEVFRS-KS--------------YDKMQADIWSLGVTIFYFITGKYPFSSKDPNLLIK---KI
|||...  ..              |.  .||||.||||...|..|| || ... . | .   ||
APELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKI
Kinase 85241.m00277.AA AMPK 59-146 35 3.3e-13 35.61 In-house 167-254 (254) Show / Hide 
Range on Protein: 59-146
Range on HMM: 167-254/254
Sequence Identity: 35% (31 aa)

APEVFRSKSYDKMQADIWSLGVTIFYFITGKYPFSSKDPNLLIKKIMSGVYMEGLIEDPQMKSLIADCLSINAPFRPTIDEILNNQVF
|||.  .| |   . |||| ||  . .. |. ||   .   | |||..|.|       |. |.||   |  .   | ||..| | . |
APEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 85241.m00277.AA S_TKc 4-146 16 1.4e-07 -65.75 SMART 14-231 (231) Show / Hide 
Range on Protein: 4-146
Range on HMM: 14-231/231
Sequence Identity: 16% (41 aa)

TVKAVHDKK----------------------------------------------VAH---------QE-------------------------------
.|. ...||                                              . .         ..                               
KVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSH

------IKPTNFLVDFYGKIKISDYGISSLYAKNPMSESFNAQRNHYAPEVFRSKSYDKMQADIWSLGVTIFYFITGKYPFSSKDPNLLIKKIMSGVYME
      .|| | |.|    |||.| |.. ..       .|   ..  ||||.   .|.|  .|.||.|.... ...|. ||.  ......|||.      
GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------

GLIEDPQMKSLIADCLSINAPFRPTIDEILN-------NQVF
    .|..|..|  ||  .   |||. |.|.        . |
----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85241.m00277.AA AMPK 8-45 34 2e-06 15.29 In-house 116-153 (254) Show / Hide 
Range on Protein: 8-45
Range on HMM: 116-153/254
Sequence Identity: 34% (13 aa)

VHDKKVAHQEIKPTNFLVDFYGKIKISDYGISSLYAKN
.|. ...|   || | | |   .||| | | | .. ..
CHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG
Kinase 85241.m00277.AA CAMKK 9-39 27 8.9e-05 10.6 In-house 193-246 (396) Show / Hide 
Range on Protein: 9-39
Range on HMM: 193-246/396
Sequence Identity: 27% (15 aa)

H-DKK-------------------VAHQEIKPTNFLVDFYG---KIKISDYGIS
| ..|                   . |  ||| | |.|  |   ..||.|.|.|
HNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVS