87414.m00372

Species: T.vaginalis
Alias: TvagK0917, 87414.m00372
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
87414.m00372.AA Protein None 328 None Fasta, JSON
87414.m00372.kin_dom Protein Kinase Domain None 276 None Fasta, JSON

Protein domain

Protein domains of 87414.m00372.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87414.m00372.AA CMGC 2-276 21 1.6e-80 264.14 In-house 17-513 (513) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-513/513
Sequence Identity: 21% (108 aa)

KAIDPQTG--------------EVVAIKKVR-IFNQNQAL--------PQAFYRETSNLQTLK-----------------HQNIINLREIFRSTS--GEE
|..| .|.              |.|||||..  |...||.        |.  .|| . |. |.                 | ||..|..||..    |.|
KCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNE

P-------------YMVFDYCEFDLDGLIHSRNP-----KGLPL-------------QTVKCYF------KQILNAVK--ACHDLN--IVHRDLKPANIF
.             |.||.|.. || ..|.. ..     ...||             ...|...      .|||...|   ||  .  |.||||||.|| 
YEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENIL

VTRGNVV--------------------KLGDFGLSRDLTKG---------------------NSQRTLGVVTPGYRAPEIILGNTQYD---------YSS
..  . .                    |..||||.| . .                      | . |  |||  ||||||.|| ..|.         .. 
INHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPI

DVWSLGAILFEMLTG--------IPLFRPLTS---------SDISQLSAIVFLLGKPN---------------EEDLAN---------------------
|.||.| |..||.||         ||| . ..         |.| ||  |. .||.|.               ||.  |                     
DMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTN

-NSYSNVNLLSMIRDCNRSLDDILRECLVG-----------------------------------EAAEAIPLILGMLKYNPSQRITVDEALCSPFL
  |..  | ... ..  .     ...   .                                   .  .|| |. .||.|.|..|||...||  |..
HWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF

S_TKc 87414.m00372.AA S_TKc 1-276 27 4.3e-79 269.99 SMART 16-231 (231) Show / Hide
Range on Protein: 1-276
Range on HMM: 16-231/231
Sequence Identity: 27% (81 aa)

MKAIDPQTGEVVAIKKVRIFNQNQALPQAFYRETSNLQTLKHQNIINLREIFRSTSGEEPYMVFDYCEF---DLDGLIHSRNPKG----LPLQTVKCYFK
.|...  ||..||||...         . ..|| . |.  .| ||..| ..|..   .. |||..||.    ||  .|..|...|    .|  ....|..
YKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY

QILNAVKACHDLNIVHRDLKPANIFVTRGNVVKLGDFGLSRDLTKGNSQRTLGVVTPGYRAPEIILGNTQYDY-SSDVWSLGAILFEMLTGIPLFRPLTS
||..|.. ||...|.||||||.||....  ..|..||||.| |       |  ..|| |.|||..    .|.. ..|.||.| ||.|||.| |.|.    
QICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP----

SDISQLSAIVFLLGKPNEEDLANNSYSNVNLLSMIRDCNRSLDDILRECLVGEAAEAIPLILGMLKYNPSQRITVDEALC-------SPFL
    |. ..  ..|                                         ||. .| ..|...|..|.|. |||         |..
----QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 87414.m00372.AA Pkinase 2-276 29 7.7e-75 259.74 Pfam 17-293 (293) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-293/293
Sequence Identity: 29% (85 aa)

KAIDPQTGEVVAIKKVRIFNQNQALPQAFYR--ETSNLQTLKHQNIINLREIFRSTSGEEPYMVFDYCEF-----DLDGLIHSRNPKGL--PLQTVKCYF
|...  ||..||.|...  ...   .|.  |  | . .. |.| ||. |...|..  . ..|||..|||      ||  .|. .. ...  . ...|.|.
KCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM

KQILNAVKACHDLNIVHRDLKPANIFVT-RGNV---VKLGDFGLSRDL-TKGNSQRTLGVVTPGYRAPEIILGNTQYDYSSDVWSLGAILFEMLTGIPLF
.||| ... ||. .|.||||||.||..  .|..   ||..||||.. . .  ||  |  ..||.|.|||.|.|.. |....|.||.| ||.|||.| |.|
YQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF

RPL--TSSDISQLSAIVFLLGKPNEEDLANNSY-SNVNLLSMIRDCNRSLDDILRECLVGEAAEAIPLILGMLKYNPSQRITVDEALCSPFL
.    . . ..|.  |.  .|.|...|  . .  |. . ..  . .     . ...  .    |.. .| ..|...|..|.| ...|..|..
PGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 87414.m00372.AA CDK 2-212 33 7.8e-68 216.05 In-house 17-248 (284) Show / Hide
Range on Protein: 2-212
Range on HMM: 17-248/284
Sequence Identity: 33% (83 aa)

KAIDPQTG-----EVVAIKKVRIFNQ-----NQALPQAFYRETSNLQTLKHQNIINLREIFRSTSGE---------EPYMVFDYCEFDLDGLIHSRNPKG
||.| |||     ..||.||.|. |.        .|.   || | |. | |.||..|.... . . .           ||||.|.. || ....      
KARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD------

LPLQTVKCYFKQILNAVKACHDLNIVHRDLKPANIFVTRGNV-----VKLGDFGLSRDLTK------GNSQRTLGVVTPGYRAPEIILGNTQYD--YSSD
     .|||..|.|...  ||. .|.||||||.|| ...  .     .|..||||.|           |   |  |||  |||||. || ..|.   . |
-----IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPID

VWSLGAILFEMLT---GIPLFRPLTSSDISQLSAIVFLLGKPNEED
.||.| |. ||.|   . |||    .|.| ||  |  ..| |.|..
MWSVGCIFAEMFTDVTRKPLFP--GDSEIDQLFKIFRICGTPTEDN

Kinase 87414.m00372.AA CDC2 2-187 40 1.2e-65 200.54 In-house 17-209 (301) Show / Hide
Range on Protein: 2-187
Range on HMM: 17-209/301
Sequence Identity: 40% (79 aa)

KAIDPQTGEVVAIKKVRIFNQNQA--LPQAFYRETSNLQTLK-HQNIINLREIFRSTSGEEPYMVFDYCEFDLDGLIH-SRNP-KGLPLQTVKCYFKQIL
|..| ||...||.||.|. ...     |.   || | |. || |.||. |.... .      ||||.|...||  .   |  . | .|.|.|| |..|||
KCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQIL

NAVKACHDLNIVHRDLKPANIFVTRGNVVKLGDFGLSRDLTKGNSQRTLG--VVTPGYRAPEIILGNTQYDYSSDVWSLGAILFEM---LTGIPLF
..|  ||   |.|||||| ||.. .  ..|..||||.|. .    . | .  |||  |||||| ||  .|. . |.||.| |. ||    |  |||
QGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLF

Kinase 87414.m00372.AA MAPK 2-276 31 3.4e-58 199.67 In-house 17-328 (328) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-328/328
Sequence Identity: 31% (98 aa)

KAIDPQ------TGEVVAIKKVRIFNQNQALPQAFYRETSNLQTL-KHQNIINLREIFRS------TSG---EEPYMVFDYCEFDLDGLIHSRNPKGLPL
.|||        .|. |||||.    ||. . .  |||   |. . .| |||.|..||.        |    .. |.|....| ||  .|.|..   |  
SAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ--PLSD

QTVKCYFKQILNA--VKACHDLNIVHRDLKPANIFVTRGNVVKLGDFGLSRDLTKGNSQR--------------TLGVVTPGYRAPEIILG--NTQYDYS
. ..  . |||..  .|  |  |..||||||.|| |.    .|..||||.| .    ...              |  |.|  ||||||.|.   . |. .
DHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKA

SDVWSLGAILFEMLT-GIPLFRPLTSSDISQLSAIVFLLGKPNEEDLANNS-YSNV-NLLSMI----RDCNRSLDDILRECLVGEAAEAIPLILGMLKYN
 |.||.| |. |||| . |||.   .. | |.  |. .||.| ||.. . . .... |...      .   .......   . .   .|| |.  ||  .
VDMWSVGCIFAEMLTDRKPLFP--GKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFD

PSQRITVDEALCSPFL
|..||||.|||  |..
PDKRITVEEALQHPYF

Kinase 87414.m00372.AA ERK7 2-276 35 5.5e-57 193.33 In-house 17-292 (292) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-292/292
Sequence Identity: 35% (101 aa)

KAIDPQTGEVVAIKKVRIFNQNQALPQAFYRETSNLQTLK-HQNIINLREIFRSTSGEEPYMVFDYCEFDLDGLIHSRNPKGLPLQTV--KCYFKQILNA
||.| .|..|||.||.    .||   |  .||   || .. | ||| | ...|       |.||.. | ||   |     ||  |. .  .. . |.|.|
KAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIR----KGNILKDIHKQYIMYQLLRA

VKACHDLNIVHRDLKPANIFVTRGNVVKLGDFGLSRDLTKGN------SQRTLGVVTPGYRAPEIILGNTQYDYSSDVWSLGAILFEMLTGIPLFRPLTS
.|  |  |..||||||.|| .    .||. |||| | ... .        .|  | |  |||||| || ..|    | ||.| || |||.| |.|    .
IKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFP--GT

SDISQLSAIVFLLGKPNEEDLA--NNSYSNVNLLSMIRDCNRSLDDILRECLVGEAAEAIPLILGMLKYNPSQRITVDEALCSPFL
| . |.  |. ...|| .||..  . .|. . | .|...  ..||.....|      .|| |.  .| .|| .|.|...||  |. 
STMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQC----CDDAIDLLKRLLVFNPKKRLTAEQALQHPYV

Kinase 87414.m00372.AA CAMK 2-276 19 3.1e-55 176.08 In-house 12-425 (425) Show / Hide
Range on Protein: 2-276
Range on HMM: 12-425/425
Sequence Identity: 19% (82 aa)

KAIDPQTG------------EVVAIKKVR-----------------IFNQ---------NQALPQAFYRETSNLQT-------LKHQNIINLREIFRS--
..|. .|.            . |||| .                  |...         ..   . ..|| . ...       |.| |||.| |.. .  
LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPH

---------TSGE-------EPYMVF---DYC---EF--DLDGLIHSRNP-------------KGLPLQTVKCYFKQILNAVKACHDLNIVHRDLKPANI
         |          . |||.   .||   |   ||   | .. .             . .. . .. ||.||. ||. ||..||||||||| ||
YFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENI

FV-TRG----------------NVVKLGDFGLSRDLTKGNSQRTL-----------------------GVVTPGYRA-PEIILG-------------NTQ
 . ...                | .|. |||... ...|......                        . ||.| | ||...|             .. 
LLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPY

YDYSSDVWSLGAILFEMLTGIPLFR-PLTSSDISQLSAIVFLLGKPNEEDLANNSYSNVNLLSMIRDCNRS-LDDILR----------ECLVGEA-----
|....|.||.| ||. ||.| | |. .  ..... . .                 ..  .|. .|. .. .  .. .              . .      
YGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E-W-------------IGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

-AEAIPLILGMLKYNPSQRITVDEALCSPFL
 .|.. || .||...|..|.|....|  |..
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 87414.m00372.AA Ciliate-E2 33-276 25 1.2e-50 172.08 In-house 82-365 (365) Show / Hide
Range on Protein: 33-276
Range on HMM: 82-365/365
Sequence Identity: 25% (83 aa)

ETSNLQTLKHQNIINLREIFRSTSGEEPYMVFDYCEF-DLDGLIHSR----------NPKGLPLQTVKCYFKQILN---------------AVKACHDLN
| ..|..|.| |||.. | | ... .  |.|..||.  ||  .| ..            | . .. .| ..||||.               |.. .|  |
EKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN

-IVHRDLKPANIFVTRGNVVKLGDFGLSRDLTKGNS-----------------QRTLG--------------VVTPGYRAPEIILG--------NTQYDY
 |.|||.|| ||..     .|. |||||..... |                   || |              . |||| ||||. |         ..|||
NIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDY

SSDVWSLGAILFEMLTGIPLFRPLTSSDISQLSAIVFLLGKPNEEDLANNSYSNVNLLSMIRDCNRSLD---------DILRECLV----GEAAEAIPLI
..|.|||| ||.|||.| | |                                    .  | .|. ...         .|   | .        |.. ||
KCDIWSLGVILYEMLFGKPPF------------------------------------QQQIKQCKIDFPCPEWQKDTQCI-Q-CKWKSWKKWSQECKDLI

LG----MLKYNPSQRIT-VDEALCSPFL
      ||...|..|||  ...|  |..
KKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 87414.m00372.AA ULK 2-185 28 4.4e-49 169.37 In-house 18-250 (324) Show / Hide
Range on Protein: 2-185
Range on HMM: 18-250/324
Sequence Identity: 28% (67 aa)

KAIDPQT---GEVVAIKKVRIFNQNQALPQ--------AFYRETSNLQTLK---HQN--IINLREIFRSTSGEEPYMVFDYCEF-DLDGLIHSR------
|... .|   ...||.|.. ....|.   .         . .| .....||   |.|  |. | ..|...     |....||.  ||. .|. .      
KGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPET

-NPKGLPLQTVKCYFKQILNAVKACHDLNIVHRDLKPANIFVTRGN------------VVKLGDFGLSRDLTKGNSQRTLG---V------VTPGYRAPE
 ..| |. | .. .||||.|. |. |. ||.|||.||.|| .. |.            |.|..|||... . ..| . ..    |       || | ||.
EEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQ

IILGN----TQYDYSSDVWSLGAILFEMLTGIP
|. |.     .||| .|.|||| |..|||.| .
ILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKY

Kinase 87414.m00372.AA ULK 5-185 30 8.6e-48 164.92 In-house 25-254 (329) Show / Hide
Range on Protein: 5-185
Range on HMM: 25-254/329
Sequence Identity: 30% (71 aa)

DPQTGEVVAIKKVR-----IFNQN---QALPQAFYRETSNLQTLK--------HQNIINLREIFRST-SGEEPYMVFDYCEF-DLDGLIHSR--------
| ...|.||.|..      ..|..   | . | . .|  ....||        |.||. | ..|... .    |....||.  ||. .|. .        
D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNH-NNIYIIMEYCNGGDLEQYIKKNKKLPEDTE

NPKGLPLQTVKCYFKQILNAVKACHDLNIVHRDLKPANIFVTRGN------------VVKLGDFGLSRDLTKG--NSQRTLGVV-------TPGYRAPEI
..| |. | .. .||||||. |. |. ||.|||.||.|| .. |.            |.|..|||... ....  . | ..  |       || | ||.|
EKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQI

ILGN----TQYDYSSDVWSLGAILFEMLTGIP
. |.     .||| .|.|||| |..|||.| |
LQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKP

Kinase 87414.m00372.AA CDKL 8-207 41 1.4e-44 150.38 In-house 23-218 (286) Show / Hide
Range on Protein: 8-207
Range on HMM: 23-218/286
Sequence Identity: 41% (83 aa)

TGEVVAIKKVRIFNQNQALPQAFYRETSNLQTLKHQNIINLREIFRSTSGEEPYMVFDYCEFD-LDGLIHSRNPKGLPLQTVKCYFKQILNAVKACHDLN
||..|||||      ...      ||   | .|||.|| ||.|.||     . ..|| ||.   |. | .  .|.|.. . |. |  |||.|.. ||  |
TGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRK--RKLHLVFEYCDHTVLHELEE--YPNGVDEHVVRKYMWQILKAINFCHKHN

IVHRDLKPANIFVT-RGNVVKLGDFGLSRDLTKGNSQRTLGVVTPGYRAPEIILGNTQYDYSSDVWSLGAILFEMLTGIPLFRPLTSSDISQLSAIVFLL
..||| || ||..| .  .|||.|||. | |.| .   |  | |  |||||  .| |||  . |.|..| .. ||..| ||. |  .||| ||  |.  |
CIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW-P-GQSDIDQLYHIQKCL

GK
|.
GP

Kinase 87414.m00372.AA Pkinase_Tyr 5-182 27 8.6e-17 57.5 Pfam 24-209 (270) Show / Hide
Range on Protein: 5-182
Range on HMM: 24-209/270
Sequence Identity: 27% (52 aa)

DPQTGEVVAIKKVRIFNQNQA-LPQAFYRETSNLQTL-KHQNIINLREIFRSTSGE-EPYMVFDYCEF-DLDGLIHSR--NPKGLPLQTVKCYFKQILNA
. .|.  ||.|...     .. . ..| || . . .| .|.||..|  .  . ..  ..|.|. |..  ||.   ...  ... |....  ..  || ..
PDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKG

VKACHDLNIVHRDLKPANIFVTRGNVVKLGDFGLSRDL-TKGNS--QRTLGVVTPGYRAPEIILGNTQYDYSSDVWSLGAILFEMLT
    .. |..||||   |. ||..|||| .||||.||.  ...   .|. | .     ||| |  .  .   ||||| |  ..|..|
MEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFT

Kinase 87414.m00372.AA TyrKc 2-254 20 1.7e-13 -4.6 SMART 19-280 (280) Show / Hide
Range on Protein: 2-254
Range on HMM: 19-280/280
Sequence Identity: 20% (58 aa)

KAIDPQTGEVVAIKKVRIFNQNQALPQAFYRETSNLQTL--KHQNIINLREIFRSTSG-----EEPYMVFDYCEF-DLDGLIHSRNPKGLPLQTVKCYFK
...     . ||.|...         ..|.|| . .  |  .|.||..|  . .. ..     | ...|. |..  ||.  .... || |....   .  
TWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCW

QILNAVKACHDLNIVHRDLKPANIFVTRGNVVKLGDFGLSRDLTKG-------NSQRT----LGV--VTPGYRAPEIILGNTQYDYSSDVWSLGAILFEM
|| .     |. |..||||   |. |.....|| .|||||||.. .          |.     |   .     ||| |     .   ||||| |  ..|.
QIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEI

LTGIPLFRP------LTSSDISQLSAIVFLLGKPNE--EDLANNSYSNVNLLSMIRDCNRSLDDILRECLVGEAAE-----AIPLIL
.|      |      .. ... ..    . . .| .  . ..          .    |   . .| ..|   ....     .|  ..
FTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS----------F--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 87414.m00372.AA CDK 252-276 40 4e-09 25.15 In-house 260-284 (284) Show / Hide
Range on Protein: 252-276
Range on HMM: 260-284/284
Sequence Identity: 40% (10 aa)

LILGMLKYNPSQRITVDEALCSPFL
|. .|| |.|..||. ..|| .|..
LLNKMLCYDPKKRISAEQALQHPYF

Kinase 87414.m00372.AA CDC2 248-276 44 6.1e-09 23.07 In-house 273-301 (301) Show / Hide
Range on Protein: 248-276
Range on HMM: 273-301/301
Sequence Identity: 44% (13 aa)

EAIPLILGMLKYNPSQRITVDEALCSPFL
|.| |.  || |.|..||...|||  |..
EGIDLLMQMLQYDPQKRISAKEALQHPYF

Kinase 87414.m00372.AA ULK 252-276 36 2e-06 18.8 In-house 305-329 (329) Show / Hide
Range on Protein: 252-276
Range on HMM: 305-329/329
Sequence Identity: 36% (9 aa)

LILGMLKYNPSQRITVDEALCSPFL
|| .||.|....||. .| .  |..
LIRRMLQYDEKDRISWEELFNHPWF

Kinase 87414.m00372.AA ULK 252-276 36 3.5e-05 14.41 In-house 300-324 (324) Show / Hide
Range on Protein: 252-276
Range on HMM: 300-324/324
Sequence Identity: 36% (9 aa)

LILGMLKYNPSQRITVDEALCSPFL
|| .||.|....||. .| .  |..
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 87414.m00372.AA CDKL 247-276 20 0.000158 11.4 In-house 257-286 (286) Show / Hide
Range on Protein: 247-276
Range on HMM: 257-286/286
Sequence Identity: 20% (6 aa)

AEAIPLILGMLKYNPSQRITVDEALCSPFL
..|. .. ..|. .|..|.|..... .|. 
KKALDFMKKCLHMDPDERMTCEQLMHHPYF