Gene 86120.m00097 (T.vaginalis)

86120.m00097

Species: T.vaginalis
Alias: 86120.m00097, TvagK0051
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
86120.m00097.AA Protein None 385 None Fasta, JSON
86120.m00097.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of 86120.m00097.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86120.m00097.AA CAMKL 1-200 38 6.6e-89 283.84 In-house 66-297 (297) Show / Hide 
Range on Protein: 1-200
Range on HMM: 66-297/297
Sequence Identity: 38% (91 aa)

MKRLDYPG----IVKFIDYLEDEGS------YYLVMEYISGGE--LFDYIISH----TRVEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDST
||.|. .|    |.|. . .|..        .||||||.||||  |||||..|     | .|. |.|.|.||   | |.||..|||||.||||.| ... 
MKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENG

--TVKIIDFGLCSI-EA-----DKPLTNKCGSPIYISPEALTG--EPYMGPPADVWALGVILYAIVDGSVPWNYKDP--------EEMQKQISTGSFLPI
  ..||||||.. . .      .. |.  |||| | .|| . |  .|| ||..|.|..||||||.| | .|..  .         ... |....  . ||
NNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPI

D-NISDECRELIVAILNPDPSKRIDITGILAHPWL
   .| .|| ||  .|...|.||. |  |. |||.
WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 86120.m00097.AA MARK 1-200 45 3.3e-86 281.8 In-house 53-262 (262) Show / Hide 
Range on Protein: 1-200
Range on HMM: 53-262/262
Sequence Identity: 45% (95 aa)

MKRLDYPGIVKFIDYLE--DEGS-YYLVMEYISGGELFDYIISH--TRVEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDST--TVKIIDFGL
||.|| | |.|. .. |  .|.   ||.|||.|||||.|||..|   | .|..|.|||.|| . | | |||||||||.||||.|. . .   .||||||.
MKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGF

CSIEA--DKPLTNKCGSPIYISPEALTGEPYMGPPADVWALGVILYAIVDGSVPWN--YKDPEEMQKQISTGSFLPIDNISDECRELIVAILNPDPSKRI
 ||.   .. |.  ||.| | .|| . ..|| ||..|.|.|||.||..| |..|.    .| .|..|.| .|..   ...|.||| ||  .|...|..|.
-SICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERP

DITGILAHPWL
.|. |. |||.
TIEEIMKHPWM
Kinase 86120.m00097.AA CAMK 1-200 28 1.9e-85 275.19 In-house 85-425 (425) Show / Hide 
Range on Protein: 1-200
Range on HMM: 85-425/425
Sequence Identity: 28% (97 aa)

MKR-------LDYPGIVKFIDYLEDEGS-------------------YYLVM---EYISGGEL----FDYIISH---------------TRVEESLAKRI
||.       || | |.|.... ||.                     .|.||   ||.|||||    ||||..|                |..|. |.|.
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRY

FKQIAYSVGYIHSKNIVHRDLKPENLLMTDST-----------------TVKIIDFGLCSI-------------------------EADKPLTNKCGSPI
|.||.  | |.||.|||||||||||.|..|.                  ..||||||.  .                         . .....  ||.| 
FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPE

YIS-PEALTG-------------EPYMGPPADVWALGVILYAIVDGSVPWNYK-------------DPEEMQKQISTGSFL-P---------------ID
|.. || | |             .|| ||..|.|..|||||. . |  |.. .             ...|. ..| .| .  |                |
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

NISDE--------CRELIVAILNPDPSKRIDITGILAHPWL
.||||        |. ||  .|..||.||. |. .|.|||.
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 86120.m00097.AA NuaK 1-200 41 1.2e-73 192.82 In-house 53-252 (252) Show / Hide 
Range on Protein: 1-200
Range on HMM: 53-252/252
Sequence Identity: 41% (83 aa)

MKRLDYPGIVKFIDYLEDEGSYYLVMEYISGGELFDYIISHTRVEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDSTTVKIIDFGLCSIEADK
|  |. | |..     |      .|||| |||||.||| .  .. |  |...| ||.  | | |  .|.||||| || |. .   .|| |||| .. .|.
MSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQ

P-LTNKCGSPIYISPEALTGEPYMGPPADVWALGVILYAIVDGSVPWNYKDPEEMQKQISTGSFLPIDNISDECRELIVAILNPDPSKRIDITGILAHPW
  |.  |||| | |||   |.|| ||  | |.|||.||..| |. |   .|  .. |||| | .      || | .||  .|  .| .|  |  |  |.|
KFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFDGHDFKHLVKQISQGAYYEPCKPSDAC-MLIRWMLMVNPRRRATIYDICHHWW

L
.
V
Kinase 86120.m00097.AA AMPK 23-200 46 1.5e-72 214.73 In-house 76-254 (254) Show / Hide 
Range on Protein: 23-200
Range on HMM: 76-254/254
Sequence Identity: 46% (83 aa)

YLVMEYISGGELFDYIISHTRVEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDSTTVKIIDFGLCSIEAD-KPLTNKCGSPIYISPEALTGEP
..||||.|||||||||..|.|..|  |.| |.||   | |.|  .||||||||||||. .   .|| ||||  .  | . |   |||| | .||  .| .
FMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKL

YMGPPADVWALGVILYAIVDGSVPWNYKDPEEMQKQISTGSFLPIDNISDECRELIVAILNPDPSKRIDITGILAHPWL
| ||  |.|  |||||| . |  |    .  .  | |  | .   ...|.|...||  .|..|| |||.|  | .|||.
YCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 86120.m00097.AA Ciliate-E2 1-200 28 7.4e-64 218.09 In-house 86-365 (365) Show / Hide 
Range on Protein: 1-200
Range on HMM: 86-365/365
Sequence Identity: 28% (84 aa)

MKRLDYPGIVKFIDYLE--DEGSYYLVMEYISGGELFDYIISH-----------TRVEESLAKRIFKQIAY---------------SVGYIHSKN-IVHR
...|. | |.|.... .  |. ..||||||..||.|||||...            .  |  .|.|.|||..                . |.|||| |.||
LEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR

DLKPENLLMTDSTTVKIIDFGLCSIEADK-------PLTN--------------------------KCGSPIYISPEALTGEPYMG--------PPADVW
|.||||.|.     .|||||||. .  |.       .. .                           ||.| | .|| | |..| .          .|.|
DIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

ALGVILYAIVDGSVPWNYKDPEEMQKQ--ISTGSFLPI-------------DNISDECRELIVA----ILNPDPSKRID-ITGILAHPWL
.||||||  . |  |.     .. .||  |.  .. ..             ...|.||  ||      .|. ||.|||. .  || |||.
SLGVILYEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86120.m00097.AA Pkinase 1-200 33 1.5e-63 222.27 Pfam 54-293 (293) Show / Hide 
Range on Protein: 1-200
Range on HMM: 54-293/293
Sequence Identity: 33% (81 aa)

MKRLDYPGIVKFIDYLEDEGSYYLVMEYISGG----ELFDYII--SHTRV--EESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDSTTV----KI
||||. | ||...|. ||....|.||||  ||    .|||||   .|...  .|  .|....||.  . |.||..|.||||||||.|. .  ..    ||
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKI

IDFGLCS---IEADKPLTNKCGSPIYISPEALTGEPYMGPPADVWALGVILYAIVDGSVPWNYK------DPEEMQKQISTGSFLPIDNIS---------
.||||.    .  .  .|  ||.| |..|| . | .| ||..|.|..|.|||  . |  |.  .      |. .| ..|  . .      .         
CDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFR

------------DECRELIVAILNPDPSKRIDITGILAHPWL
            .||...|  .|..||.||. .. || |||.
HWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86120.m00097.AA QIK 1-200 36 6.8e-63 215.27 In-house 52-272 (272) Show / Hide 
Range on Protein: 1-200
Range on HMM: 52-272/272
Sequence Identity: 36% (81 aa)

MKRLDYPGIVKFIDYLEDEGSYYLVMEYISGGELFDYIISHTR--------------------VEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLM
||.|. | |.|  . .| .   |.|.|| |.||.|||...| |                    ..|. |.|.|.||.  | | |..|||||||| ||.|.
MKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILL

TDSTTVKIIDFGLCS-IEADKPLTNKCGSPIYISPEALTGEPYMGPPADVWALGVILYAIVDGSVPWNYKDPEEMQKQISTGSF-LPIDNISDECRELIV
     .||.|||.    . ...|   |||| |  || . |. | || .|.| .||.||. | |. |   |  ..... .  | | .|   .| .| .|| 
DNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPF-FMSQDCEHLIR

AILNPDPSKRIDITGILAHPWL
  |  ||..|. |  |. |.|.
HMLVVDPEHRYTIMQICQHRWM
Kinase 86120.m00097.AA GIN4 1-200 41 4.9e-62 196.77 In-house 88-293 (293) Show / Hide 
Range on Protein: 1-200
Range on HMM: 88-293/293
Sequence Identity: 41% (85 aa)

MKRLDYPGIVKFIDYLEDEGSYYLVMEYISGGELFDYIISHTRVEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDSTT-VKIIDFGLCSIEAD
|| .. | ...  |  | .   |||.||. .||||.|...| .. |  | ..|.||   | | |. ||.||||||||||.      .|| |||.  .| |
MKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETD

-KPLTNKCGSPIYISPEALTGEPYMGPPADVWALGVILYAIVDGSVPWNYK--DPEEMQKQISTGSF-LPID-NISDECRELIVAILNPDPSKRIDITGI
 | |   |||| | .||   | || | ..|||. ||||.|.. | .|..       ..  ..  | . .| | .|| | ..||  ||  || ||| .  |
NKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDI

LAHPWL
| || .
LKHPLI
Kinase 86120.m00097.AA MELK 1-200 40 4.8e-58 196.84 In-house 51-254 (254) Show / Hide 
Range on Protein: 1-200
Range on HMM: 51-254/254
Sequence Identity: 40% (82 aa)

MKRLDYPGIVKFIDYLEDEGSYYLVMEYISGGELFDYIISHTRVEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDSTTVKIIDFGLCSI---E
.| | .  | ..  |.| |  ...|||| .|||.|||||.. |.||. .. .|.||  .. |.||.   ||||||||||...   .|.||||||.    .
LKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGR

ADKP-LTNKCGSPIYISPEALTGEPYMGPPADVWALGVILYAIVDGSVPWNYKDPEEMQKQISTGSFLPIDNISDECRELIVAILNPDPSKRIDITGILA
 |.  |   |||| |  || . |  |.|  ||||..|..||... | .|..    . | |.|  | .   . .| | ..|. ..|  || ||| .  .| 
KDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLN

HPWL
|||.
HPWV
Kinase 86120.m00097.AA S_TKc 1-200 31 1.4e-56 195.21 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-200
Range on HMM: 19-231/231
Sequence Identity: 31% (74 aa)

MKRL-----------------------DYPGIVKFIDYLEDEGSYYLVMEYISG--GELFDYIISHTR------VEESLAKRIFKQIAYSVGYIHSKNIV
 ..                        . | |||..|. .| ...|.||||..|  |.||||| .. |        |  |.....||.  . |.||..|.
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII

HRDLKPENLLMTDSTTVKIIDFGLCSIEADKPLTNKCGSPIYISPEALTGEPYMGPPADVWALGVILYAIVDGSVPWNYKDPEEMQKQISTGSFLPIDNI
||||||||.|...  ..||.||||. .      |  ||.| |..|| |   .| ....|.|..|.|||  . |  |.   ....| |.|           
HRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------

SDECRELIVAILNPDPSKRIDITGILA-------HPWL
|.|....|  .|. ||.||. .  .|.       |||.
SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86120.m00097.AA Ciliate-E2-Unclassified 1-200 26 6.1e-56 192.16 In-house 75-352 (352) Show / Hide 
Range on Protein: 1-200
Range on HMM: 75-352/352
Sequence Identity: 26% (75 aa)

MKRLDYPGIVKFIDYLEDEGSYYLVMEYISGGELFDYIISHTR-----------------VEESLAK-----RIFKQIAYSVGYIHSKN-IVHRDLKPEN
.. .. | |||.... .|.   |.||||. ||.|..|| .                    ..|  ||     ..|.||     |.|.|| |.|||.||||
LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN

LLMTDST---TVKIIDFGLCS-----------------IEADKPLTNKCGSPIYI----SPEALTGEPYMGP---PADVWALGVILYAIVDGSVPWNYKD
.|....     .||||||...                 |  .. .. .||.|.|.    .|| | |. | ..    .|.|.||||||... |  | ....
ILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNN

PEE----------------MQKQISTGSFLPI--------DNISDECRELIV----AILNPDPSKRIDITGILAHPWL
 |.                ....|  . .           ...|.|. ..|      .|. .|.|||..  || |||.
CEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86120.m00097.AA TyrKc 1-195 21 8.9e-11 -48.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-195
Range on HMM: 1-280/280
Sequence Identity: 21% (60 aa)

M-------------------------------------------KRL--DYPGIVKFIDYLEDE-------GSYYLVMEYISGGELFDYIISHTR-VEES
                                            ..|  . | ||... .  ..       . ...|||| ..| | ||. .| . .  .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

LAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDSTTVKIIDFGLCSIEADK-------PLTNK----CG---SPI-YISPEALTGEPYM--GPPADVW
    .  |||    |.||||..||||   | | ..  |||| ||||.    |.           |    .|    ||   .||..    |    .  |||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFTTKSDVW

ALGVILYAIV-DGSVPWNY-----KDPEEMQKQISTGSFLPIDNI---------SDECRELIVAILNPDPSKR---IDITGIL
. || .. |  .|  |.       ....|. ... .|  .|.            .||  ...    . ||..|    .|  ..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 86120.m00097.AA Pkinase_Tyr 1-94 36 1e-08 30.13 Pfam 57-158 (270) Show / Hide 
Range on Protein: 1-94
Range on HMM: 57-158/270
Sequence Identity: 36% (37 aa)

MKRL-DYPGIVKFIDYLE-DEGS--YYLVMEYISGGELFDYIISH----TRVEESLAKRIFKQIAYSVGYIHSKNIVHRDLKPENLLMTDSTTVKIIDFG
|| | . | ||...     ....  .|.||||  .| | ||  .|     ..  .    .  |||    | .|||..||||   | | |.. .||| |||
MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

LC
|.
LA