Gene 92030.m00090 (T.vaginalis)

92030.m00090

Species: T.vaginalis
Alias: TvagK0093, 92030.m00090
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
92030.m00090.AA Protein None 350 None Fasta, JSON
92030.m00090.kin_dom Protein Kinase Domain None 202 None Fasta, JSON

Protein domain

Protein domains of 92030.m00090.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92030.m00090.AA AGC 1-202 20 4.5e-83 213.83 In-house 74-395 (395) Show / Hide 
Range on Protein: 1-202
Range on HMM: 74-395/395
Sequence Identity: 20% (66 aa)

MSRIN----------HPNIIQ-LHRVLKSQTK--YFLILDLIR---------GK-DLSEII-G--QNGCLSESTARIYFHQ-------IIDAIDFLHR-N
....|          ||.|.. ||   .....   .......          |  .|  .. |  ..|...|..||.|. .       |. |...||. .
LEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHM

GIIHRD-IKPDNILIDKNDKAYLIDFGLSARNIT--------------------------------------------------QSDLFTDMLG--TPNY
|||||| .||.|||.|..    | ||||. ....                                                  . |. . . |  ||.|
GIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEY

LAPEVITETPYRGQSVDLYA--AGLILYVMLTGEVPFHADS---------SQDVIQNIIL-------SELYIP----------NFISDAAAKLIRRLTHR
.|||..      |...| ..   | ..| ||||  ||..|.         ... . . |.        .. .|           ..|. |  ||..| ..
MAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCK

NPRLRYT----------IEDVRKDEWF
.|. | .          .|.... .||
DPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 92030.m00090.AA CAMKL 1-202 31 7.9e-78 247.92 In-house 66-297 (297) Show / Hide 
Range on Protein: 1-202
Range on HMM: 66-297/297
Sequence Identity: 31% (74 aa)

MSRIN---HPNIIQLHRVLKSQTK------YFLILDLIRGKD--LSEIIGQNGC----LSESTARIYFHQIIDAIDFLHRNGIIHRDIKPDNILIDKND-
|...|   |||||.|. |.  ...      ..|.. .. | .  | . | ..|.    ..|. || || ||..|....|..||.||||||.|||.|.|. 
MKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGN

-KAYLIDFGLSAR---N-ITQSDLFTDMLGTPNYLAPEVITE--TPYRGQSVDLYAAGLILYVMLTGEVPFHADS-------SQDVIQNIILSELYIPN-
 .. .||||.|.    . ..  ....   |.|.| |||..    .||.|. ||  ..| |||.|..|..|| .|.        .    ..| .  | |. 
NNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPI

--FISDAAAKLIRRLTHRNPRLRYTIEDVRKDEWF
  ..|  .  |||..  .||  |.||.......|.
WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 92030.m00090.AA CAMK 1-202 21 3.4e-75 241.56 In-house 85-425 (425) Show / Hide 
Range on Protein: 1-202
Range on HMM: 85-425/425
Sequence Identity: 21% (74 aa)

MSR-------INHPNIIQLHRVLKS-------------------QTKYFLIL---DLIRGK----DLSEIIGQNGC---------------LSESTARIY
|..       ..|||||.|. |  .                   ........   ... |     || . | ..||               ..|. || |
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRY

FHQIIDAIDFLHRNGIIHRDIKPDNILIDKND-----------------KAYLIDFGLSARNIT-----------------------QSDLFTDMLGTPN
|.||..|....| ..|.|||.||.|||.|.|.                 .  .||||.... .                        . ...... ||| 
FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPE

YLA-PEVITE-------------TPYRGQSVDLYAAGLILYVMLTGEVPFHADSSQDVIQ-------------NIILSELY-IPNF--------------
| | |||.                || |...|  ..| |||.||.|. || .|. .. ..             .|.  . . .| .              
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

-ISDA--------AAKLIRRLTHRNPRLRYTIEDVRKDEWF
 |||         .  |||..  ..|  |.|||.. ...|.
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 92030.m00090.AA AMPK 1-202 36 4.5e-69 204.22 In-house 53-254 (254) Show / Hide 
Range on Protein: 1-202
Range on HMM: 53-254/254
Sequence Identity: 36% (75 aa)

MSRINHPNIIQLHRVL-KSQTKYFLILDLIRGKDLSEIIGQNGCLSESTARIYFHQIIDAIDFLHRNGIIHRDIKPDNILIDKNDKAYLIDFGLSARNIT
.  ..||.|||| .|. ...|  |...  . | .| . | ..| |.|  |. .| ||| ... .||..| ||| || |.|.|.| .  . |||||    .
LKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLS-NMMK

QSDLFTDMLGTPNYLAPEVITETPYRGQSVDLYAAGLILYVMLTGEVPFHADSSQDVIQNIILSELYIPNFISDAAAKLIRRLTHRNPRLRYTIEDVRKD
  ..     | |.| |||.|.  .| |  ||.   | |||.|| |  ||  ..  .  ..|.  | ||| |.|. |. ||...   .|  |.||.|.|..
DGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNH

EWF
.||
PWF
Kinase 92030.m00090.AA MARK 1-202 36 9.6e-68 220.56 In-house 53-262 (262) Show / Hide 
Range on Protein: 1-202
Range on HMM: 53-262/262
Sequence Identity: 36% (78 aa)

MSRINHPNIIQLHRVLK--SQTK-YFLILDLIRGKDLSEIIGQN--GCLSESTARIYFHQIIDAIDFLHRNGIIHRDIKPDNILIDKND--KAYLIDFGL
|....|||||.|. |      ..  .||.... |..| . | .   |.|.|. || .|.||. |. ..|...|.||||||.|||||.|   .. .||||.
MKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGF

SARNITQSDLFTDMLGTPNYLAPEVITETPYRGQSVDLYAAGLILYVMLTGEVPFHADS--SQDVIQNIILSELYIPNFISDAAAKLIRRLTHRNPRLRY
|.. |.   . .   ||| | |||..   || |. || .. | .||.|..| .|| .|.    .  ..|   .  || ..|. . .||.||   ||  | 
SIC-IPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERP

TIEDVRKDEWF
|||.. |..|.
TIEEIMKHPWM
Kinase 92030.m00090.AA Pkinase 1-202 29 1.4e-64 225.68 Pfam 54-293 (293) Show / Hide 
Range on Protein: 1-202
Range on HMM: 54-293/293
Sequence Identity: 29% (72 aa)

MSRINHPNIIQLHRVLKSQTKYFLILDLIRGK----DLSEIIG--QNGCL--SESTARIYFHQIIDAIDFLHRNGIIHRDIKPDNILIDKNDKA----YL
| |.|||||..|...  . ... ..... .|     ||...|   ..||.  || ... |. ||. .....|..||||||.||.|||||.|.       .
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKI

IDFGLSAR--NITQSDLFTDMLGTPNYLAPEVITETPYRGQSVDLYAAGLILYVMLTGEVPFHAD------SSQDVIQNIILSELYIPNFIS--------
.||||..   .  .|  .|.  |||.|.||||| . .| |..|| ...|.||| ||.|. ||  .      . . .|..|   .|  . . .        
CDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFF

-------------DAAAKLIRRLTHRNPRLRYTIEDVRKDEWF
             ... ..|... ...|  |.|.|.. ...||
RHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 92030.m00090.AA Ciliate-E2 1-202 22 1.9e-62 213.2 In-house 86-365 (365) Show / Hide 
Range on Protein: 1-202
Range on HMM: 86-365/365
Sequence Identity: 22% (65 aa)

MSRINHPNIIQLHRVLK--SQTKYFLILDLIRGKDLSEIIGQN-----------GCLSESTARIYFHQIID---------------AIDFLHRNG-IIHR
....||||||... . .  ......|..... |.|| ..| .|           ....|  .. .. ||..               |. .|| .. ||||
LEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR

DIKPDNILIDKNDKAYLIDFGLSARNITQSD---------LFTDML-----------------------GTPNYLAPEVITETPY--------RGQSVDL
||||.|||.       .|||||| .. ....         ....                         |||.|.|||..   .|         . ..|.
DIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI

YAAGLILYVMLTGEVPFHADSSQDVIQNIILSELYIPNF------------------ISDAAAKLIRR----LTHRNPRLRYT-IEDVRKDEWF
...| ||| ||.|. ||        .|.|.  .. .|..                  .|. .  ||..    .  ..|  |.| .|.. . .||
WSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 92030.m00090.AA RSK 1-202 28 2.7e-62 213.27 In-house 54-278 (278) Show / Hide 
Range on Protein: 1-202
Range on HMM: 54-278/278
Sequence Identity: 28% (65 aa)

MSRIN-HPNIIQLHRVLKSQTKYFLILDLIRGKDLSEIIGQNGC---LSESTARIYFHQIIDAIDFLHRNGIIHRDIKPDNILIDK---NDKAYLIDFGL
..|.. ||.|..|| . . ..| .||....|| .| . . . ..   .||..|..|. .|. |...||  ||||||.||.||| |    .    |.|||.
LERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGF

SAR-NITQSDLFTDMLGTPNYLAPEVIT----ETPYRGQSVDLYAAGLILYVMLTGEVPFHA---DSSQDVIQNIILSE--LYIP--NFISDAAAKLIRR
.   .. .. .     .| .|.|||...    .  . ....|..  | ..| |||| .||..   .........|   .  | .|  ...|..|  |||.
CKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGH-DKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRK

LTHRNPRLRYT-----IEDVRKDEWF
. ||.|  |..     .|......||
MLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 92030.m00090.AA Ciliate-E2-Unclassified 1-202 24 3.3e-61 209.65 In-house 75-352 (352) Show / Hide 
Range on Protein: 1-202
Range on HMM: 75-352/352
Sequence Identity: 24% (68 aa)

MSRINHPNIIQLHRVLKSQTKYFLILDLIRGKDLSEIIGQN-----------------GCLSESTAR-----IYFHQIIDAIDFLHRNG-IIHRDIKPDN
.. ..||.|. .. . ... . ........|.||...| ..                  ...|  |.      || ||......||... ||||||||.|
LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN

ILIDKND---KAYLIDFGLSA---------------RNITQSDLFTDMLGTPNYL----APEVITETPYRG---QSVDLYAAGLILYVMLTGEVPFHADS
||.|.|    .  .||||.|                ..|......... |||||.    ||||. .  | .    ..| .. | ||| ||.|. || . .
ILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNN

SQD----------------VIQNIILSELYIPN--------FISDAAAKLIR----RLTHRNPRLRYTIEDVRKDEWF
. .                ..|||.  ....|.         .|. |. .|.    ..   ||  |.|.|.. .  ||
CEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 92030.m00090.AA ULK 1-202 25 3.3e-53 183.1 In-house 64-329 (329) Show / Hide 
Range on Protein: 1-202
Range on HMM: 64-329/329
Sequence Identity: 25% (69 aa)

MSRIN--------HPNIIQLHRVLKSQ--TKYFLILDLIRGKDLSEIIGQNGCLSEST----------ARIYFHQIIDAIDFLHRNGIIHRDIKPDNILI
| ...        ||||..|. .....  . ...|...  | ||...| .|. |.|.|          |...|.||. .  .|| ..||||||||.||||
MKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILI

DKNDKAY------------LIDFGLSARNITQS----DLFTDML------GTPNYLAPEVIT----ETPYRGQSVDLYAAGLILYVMLTGEVPFHADSSQ
....  .            . |||. |. .. .    .... ..      ||| | ||...     . ||    .|..  | |.| ||.|..|| |   .
HNGQPKTDSKKVHPNGVLKIADFGF-AKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FN

DVIQNIILSELYIP--------------------NFISDAAAKLIRRLTHRNPRLRYTIEDVRKDEWF
| . .|| ... .|                    . ||.    ||||.  .... | ..|.. . .||
DQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 92030.m00090.AA S_TKc 1-202 27 1.2e-50 175.45 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-202
Range on HMM: 19-231/231
Sequence Identity: 27% (65 aa)

MSRI-----------------------NHPNIIQLHRVLKSQTKYFLILDLIRG--KDLSEIIGQNGC------LSESTARIYFHQIIDAIDFLHRNGII
  .                        .||||..|. |  . .......... |   || ..| ..|.      ..| .|| |..||..|....|..|||
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII

HRDIKPDNILIDKNDKAYLIDFGLSARNITQSDLFTDMLGTPNYLAPEVITETPYRGQSVDLYAAGLILYVMLTGEVPFHADSSQDVIQNIILSELYIPN
|||.||.|||.|.     ..||||...        | . |||.|.||||.   .| . ..| .. | ||| ||.|. ||.    .... ..|.       
HRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-------

FISDAAAKLIRRLTHRNPRLRYTIEDVRK-------DEWF
  |. |  .||.. ...|. |.|. .. .       ..||
--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92030.m00090.AA ULK 1-202 25 1.5e-50 174.26 In-house 64-324 (324) Show / Hide 
Range on Protein: 1-202
Range on HMM: 64-324/324
Sequence Identity: 25% (67 aa)

MSRIN---HPN--IIQLHRVLKSQ--TKYFLILDLIRGKDLSEIIGQNGC---------LSESTARIYFHQIIDAIDFLHRNGIIHRDIKPDNILIDKND
|  ..   |||  |..|. .....  . ...|...  | ||...| .|.          |||. |...|.||. .  .|| ..||||||||.|||| ...
MKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQ

KAY------------LIDFGLSAR-NI--TQSDLFTDML------GTPNYLAPEVIT----ETPYRGQSVDLYAAGLILYVMLTGEVPFHADSSQDVI--
  .            . |||..   .    . .... ..      ||| | ||...     . ||    .|..  | |.| ||.|..|| ..  .| .  
PKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY

-----QN-------IILSELYIP-----NFISDAAAKLIRRLTHRNPRLRYTIEDVRKDEWF
     .|       |    . .|     . ||.    ||||.  .... | ..|.. . .||
IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 92030.m00090.AA TyrKc 1-201 17 2e-08 -86.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-201
Range on HMM: 1-280/280
Sequence Identity: 17% (49 aa)

MS-------------------------------------------RI--NHPNIIQLHRVLKSQ-------TKYFLILDLIRGKDLSEIIGQNGC-LSES
 .                                           ..  .||||..|. |  .|         ..... .  . || . .  ..  |. .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

TARIYFHQIIDAIDFLHRNGIIHRDIKPDNILIDKNDKAYLIDFGLSARNITQS-------DLFTDML--GTP-----NYLAPEVITETPYRGQSVDLYA
.   . .|| .  ..||....||||.   |.|...|  .   |||| .|.|.         |  . .   |.        .|||.| .  .  .| | ..
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL-SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-DVWS

AGLILYVMLT-GEVPFHA-----DSSQDVIQNIILS-ELYIPNF--------ISDAAAKLIRRLTHRNPRLRYTIEDVRKDEW
 |  .. ..| |. |         | |.||...     . .|           .|.  .....  |..|  | | ... ....
FGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 92030.m00090.AA APH 65-94 20 0.000844 13.84 Pfam 169-202 (248) Show / Hide 
Range on Protein: 65-94
Range on HMM: 169-202/248
Sequence Identity: 20% (7 aa)

RNGIIHRDIKPDNILID---KNDKA-YLIDFGLS
. ...|.| .|.|...|    ...  ..||.. .
PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDA