Gene 96280.m00134 (T.vaginalis)

96280.m00134

Species: T.vaginalis
Alias: TvagK0255, 96280.m00134
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
96280.m00134.AA Protein None 314 None Fasta, JSON
96280.m00134.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 96280.m00134.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 96280.m00134.AA S_TKc 14-257 30 2e-77 264.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 30% (79 aa)

MTFQSVIAKGGFGTIYLVFSLQYQQFFALKKIPENRFNKAEVDCLMEIDHPNIISLYKYYKFQEYIYLLMEYCPY---DLETLLKKESE------ICEDQ
 ..  .| ||.||. |..     .. .|.|.|.  .  . |...|.. .||||. || ..   ...|. ||||.    || ...||         . | .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LKRYCYGILQGIKACHDRNISHSDIKPSNFLIDKYGRIKVCDFGLSVMHFNCADCHSFRGTIYFMAPEILCKKGYDSIKADIWSLGITFFYMATQTFPFN
 ..|.| |..... ||...| | |.||.| |.|.  .||.|||||.         ..| || ..||||.|   ||.  |.|.||.|.... |..   || 
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

GDDRKDIIKEVTTGMYPISKVESAALRQVITSCLQIDPLARPTVDDLLN-------MPFF
  . . ..| .           |  ... |  ||| ||  |||. ..|.       .|.|
--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 96280.m00134.AA Pkinase 14-257 27 7.1e-70 243.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

MTFQSVIAKGGFGTIYLVFSLQYQQFFALKKIPENRFNK---------AEVDCLMEIDHPNIISLYKYYKFQEYIYLLMEYCPY-----DLETLLK--KE
 .. ..| .|.||. |.     ... .|.|.|.  . ..         .|.  . ...||||. || ..    .||. ||||.      || ....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SEI--CEDQLKRYCYGILQGIKACHDRNISHSDIKPSNFLIDKYGRI----KVCDFGLSVM--HFNCADCHSFRGTIYFMAPEILCKKGYDSIKADIWSL
  .   |...|.|.| ||.|.. ||...| | |.||.|.|||. | |    |.|||||.    . |   ...| ||...||||.. .  |.. |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITFFYMATQTFPFNGD------DRKDIIKEVTTGMYPISKVES---------------------AALRQVITSCLQIDPLARPTVDDLLNMPFF
|.....|..  .|| |.      | . .|...  . .. .  ..                      .....|..||. ||  ||| ...|. |.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96280.m00134.AA CAMK 19-257 18 4.4e-65 208.37 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

VIAKGGFGTIYLVFSLQYQ------------QFFALKKIP---------------------------------ENRFNKAEVDCLME-------IDHPNI
.. .|.||. .|..  . .            | .| | |.                                   .. . |.....        .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLYKYYK------------FQEY--------IYLLM---EYCPYD------LETLLKKESE--------------ICEDQLKRYCYGILQGIKACHDRN
|.|| .|             . ..        .|. |   |||.        .. . .....              ..|.. .||   |..... ||..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ISHSDIKPSNFLIDKY-----------------GRIKVCDFGLS--VMH----FNCAD------------------CHSFRGTIYFMA-PEILCK-----
| | |.|| | |.|.                  . ||..|||..  ...    |.|.|                  .. | || ..|| ||.| .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KGYDSIKADIWSLGITFFYMATQTFPFNGDDRKDIIK-------------EVTTGMYP-ISKVESA-----------------------ALR
        | |.. |.|.||.|.  . | . ..||.||....|..              ...| |  ...  |                          .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

QVITSCLQIDPLARPTVDDLLNMPFF
. | ..|| ||  |.|... || |..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 96280.m00134.AA CAMKL 43-257 29 1.2e-59 188.97 In-house 36-297 (297) Show / Hide 
Range on Protein: 43-257
Range on HMM: 36-297/297
Sequence Identity: 29% (79 aa)

KKIPENRFNKA---------------EVDCLMEID---HPNIISLYKYYKFQEY------IYLLMEYCP-YD--LETLLKKESE----ICEDQLKRYCYG
||| .. ..|.               |. ... ..   |||||.||  .  .|.      ||| ||||.  .  |   ..|. .    . |.. .||   
KKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQ

ILQGIKACHDRNISHSDIKPSNFLIDKYG--RIKVCDFGLSVMHFNC----AD-CHSFRGTIYFMAPEILCK--KGYDSIKADIWSLGITFFYMATQTFP
|. ... ||...| | |||| | |.|. |   ||..|||.| |. .|     . .. | |.  .|||||. .  | ||  |.||||.|.. . | . ..|
IVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLP

FNGDD---------RKDIIKEVTTGMYPISKVESAALRQVITSCLQIDPLARPTVDDLLNMPFF
|..|.         ..  .. .. ...|| .  |  .|. | . || .|  |||.....| |..
FDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 96280.m00134.AA AGC 14-257 19 2e-57 146.01 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-395/395
Sequence Identity: 19% (76 aa)

MTFQSVIAKGGFGTIYLVFSL------QYQQFFALKKIP-----------ENRFNKAE------------VDCLMEID----------HPNIIS-LYKYY
  |  || ||.||. |||         . ....|.|..            . . ...|             . |....          ||.|.. |.  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KFQEY--IYLLMEYCP----------Y-DLETLLK---KESEICEDQLKRYCY-------GILQGIKACHD-RNISHSD-IKPSNFLIDKYGRIKVCDFG
. ...  .|..|||.|            .| . |.   ||    |.. . |.         |. ..   |. ..| | | .|| | |.|. | || .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSVMHFN-CAD--------------------------------------------------CHSFRG--TIYFMAPEILCKKGYDSIKADIWS--LGITF
|. .  | . .                                                  ...| |  |  .||||||      .  .|.||  ||. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

FYMATQTFPFNGD----------DRKDIIKEVT------TGMYPIS----------KVESAALRQVITSCLQIDPLARPT----------VDDLLNMPFF
. | |   ||.||          ..... . .       .   ..           .  |  ..  |. .|. ||  |..          .... | |.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 96280.m00134.AA Ciliate-E2 14-257 22 8.7e-56 189.97 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

MTFQSVIAKGGFGTIYLV-------------FSLQY-----------QQFFALKKIPEN--RFNKAEVDCLMEID----------------HPNIISLYK
  |. .| .|.||..|..             .  |.           ....|.| . .|  .. | | . ..||.                ||||| .| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YYK--FQEYIYLLMEYCPY-DLETLLKKESEIC-----------EDQLKRYCYGILQ---------------GIKACHDRN-ISHSDIKPSNFLIDKYGR
...   ...||| |||| . ||. ..|. .  .           | . |.. . |||               ... .| .| | | ||||.| |.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKVCDFGLS-------------VMHFNCADCHS--------------------FRGTIYFMAPEILCKKGY--------DSIKADIWSLGITFFYMATQT
||..|||||             ... .. . ..                    . || ..|||||| .|.|         . |.||||||.....| .  
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPFNGDDRKDIIKEVTTGMYPIS------------------KVESAALRQVITS----CLQIDPLARPT-VDDLLNMPFF
.||        ...   . . ..                  |  |    . |      .|| ||  |.|  ...|| |.|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 96280.m00134.AA MARK 15-257 32 3.5e-54 175.59 In-house 2-262 (262) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-262/262
Sequence Identity: 32% (84 aa)

TFQSVIAKGGFGTIYLVFSLQYQQFFALKKIP---ENRFNK-----AEVDCLMEIDHPNIISLYKYYK--FQEY-IYLLMEYCP-YDLETLLKKE--SEI
 .  .| .|.... .|. .. ... .|.| ..    |....      |.. .. .||||||.|...      .  ||| |||..  .|   .|.     .
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

CEDQLKRYCYGILQGIKACHDRNISHSDIKPSNFLIDKYG--RIKVCDFGLSVMHFNCADCHSFRGTIYFMAPEILCKKGYDSIKADIWSLGITFFYMAT
.|.  .|..  |. ... ||..|| | |||| | |||. |   || .|||.|.   .     .| ||  .|||||. || ||  |.||||||.  ..| .
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVC

QTFPFNGDD--RKDIIKEVTTGMYPISKVESAALRQVITSCLQIDPLARPTVDDLLNMPFF
 .||| ||.   |.. |....|.|.|    |. .|. | . |...|  |||...... |..
GYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 96280.m00134.AA STE 14-257 22 4e-52 179.5 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-359/359
Sequence Identity: 22% (81 aa)

MTFQSVIAKGGFGTIYLVFSLQ---------------YQQFFALKKIP----------------------ENRFNKAEVDCLMEID--HPNIISLYKYYK
 .....| ||.||| |.                     ....| |...                      |    . |.. ... .  ||||.  | .| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FQ-------EYIYLLMEYCP-YDLETLLK------KE--------SEICEDQLKRYCYGILQG-IKACHDRNISHSDIKPSNFLIDKYGRIKVCDFGLSV
         ..... |||..   |. ..|      |.        . . |.|....|. ||.|  .  |. .| | ||||.| |.     .| ||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

MHFN----------------CA-DCHSFRGTIYFMAPEILCK------KGYDSIKADIWSLGITFFYMATQTFPFNGDDRKDIIKEVT--TGMY------
   .                ..  . .| ||  .||||.. .      |||| .|.||||||.|   |||   |.        . . .  ..|.      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----PISKVES----------------------AALRQVITSCLQIDPLARPTVDDLLN--MPFF
     |. . ..                        ... |  |||.||  |||...||.   ||.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 96280.m00134.AA Ciliate-E2-Unclassified 15-257 23 3.7e-51 175.69 In-house 2-352 (352) Show / Hide 
Range on Protein: 15-257
Range on HMM: 2-352/352
Sequence Identity: 23% (84 aa)

TFQSVIAKGGFGTIYLV-FSLQYQQFFALKKIP----------------------ENRFNKAEVDC----LME---IDHPNIISLYKYYKF--QEYIYLL
... .| .||||..|..  . |. |..|.| .                       .|. .|  ..     .|    ..||... ....| |  ...||. 
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCPY-DLETLLKKESE-----------------ICEDQLK-----RYCYGILQGIKACHDRN-ISHSDIKPSNFLIDKYG---RIKVCDFGLS-----
||||.. ||.  .|| .                  . | | |     .|.. ||||.. .|  | | | ||||.| |.|. |   .||..|||.|     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----VMHFN--------CADCHSFRGTIYFM----APEILCKKGYDS---IKADIWSLGITFFYMATQTFPFNGDDRKD----------------IIKEV
      ...           ...| ||...|    |||.|....||    .|.||||||. ...| ....||.. ....                .... 
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

TTGMYPISKVE--------SAALRQVIT----SCLQIDPLARPTVDDLLNMPFF
  . . ..| .        |      |.    ..|. .|  |.| ...|| |.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 96280.m00134.AA ULK 14-257 25 1.7e-49 170.72 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-324/324
Sequence Identity: 25% (82 aa)

MTFQSVIAKGGFG-TIYLVFSLQY---QQFFALKKIP-----ENRFN----------KAEVDCLMEID---HPN--IISLYKYYKFQ--EYIYLLMEYCP
     .. || || . |  .  .    .|..| |.|.     ..  .          | |.  . ...   |||  |. ||.... .   .||. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

Y-DLETLLKKESE---------ICEDQLKRYCYGILQGIKACHDRNISHSDIKPSNFLIDKY------------GRIKVCDFGLSVM-H---FNCADCHS
  |||...||  .         . |.. . ... |..| |. |..|| | ||||.| || .             |..|..|||.. .     ..  .|..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FR------GTIYFMAPEILC----KKGYDSIKADIWSLGITFFYMATQTFP----FNGDDRKDIIKE----------VTTGMYPISKVE-----SAALRQ
.       || ..|||.||     .| |...|.||||||. |..| .   |    || .. . |.|.          . .   .. |..     |  ...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VITSCLQIDPLARPTVDDLLNMPFF
 |  .||.|.  | . ....|.|.|
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 96280.m00134.AA ULK 14-257 25 5e-48 165.76 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-329/329
Sequence Identity: 25% (83 aa)

MTFQSVIAKGGFGTIYLVFSLQY----QQFFALKKIP---ENRFN------------KAEVDCLMEID--------HPNIISLYKYYKFQ--EYIYLLME
     .. || ||. |  .  .     .. .| |.|.   .|..|            | |.. . ...        ||||. ||.... .   .||. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPY-DLETLLKKESE----------ICEDQLKRYCYGILQGIKACHDRNISHSDIKPSNFLIDKY------------GRIKVCDFGLSVM-HFN---CA
||.  |||...||  .          . |.. . ... ||.| |. |..|| | ||||.| ||..             |..|..|||.. .   .    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

DCHSFR------GTIYFMAPEILC----KKGYDSIKADIWSLGITFFYMATQTFPFNGDDRKDII-----KEVTTG--------MYPIS-------KVES
. ...       || ..|||.||     .| |.. |.||||||. |..| .   ||..    | .     |..  .          |.        .. |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

AALRQVITSCLQIDPLARPTVDDLLNMPFF
  ... |  .||.|.  | . ..|.|.|.|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 96280.m00134.AA NEK 22-257 28 2.2e-44 153.74 In-house 9-286 (286) Show / Hide 
Range on Protein: 22-257
Range on HMM: 9-286/286
Sequence Identity: 28% (80 aa)

KGGFGTIYLVFSLQYQQF-----FALKKIPENRFNK--------AEVDCLMEIDHPNIISLYKYYKFQE--YIYLLMEYCPY--DLETL---LKKES---
.| ||. |.| . . ..      ...|||  .. .          ||  | ...||||.. |  .  ..  ...  ||||    ||. .   .||     
QGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKG

-EICEDQLKRYCYGILQGIKACHDR-----NISHSDIKPSNFLIDKYGR----IKVCDFGLSVMHFNCAD-CHS-FRGTIYFMAPEILCKKGYDSIKADI
  . |.|  .... .. ..| .|||     .| | ||||.|  ..| ..    .|. |||.| .  . .|  .. . || |.|.||..  |.|.. |.||
KYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNN-KSDI

WSLGITFFYMATQ--TFPFNGD--DRKDIIKEVTTG-MYP-ISKV--ESAALRQVITSCLQIDPLARPTVDDLLNMPFF
||||   . |.|.    ||...  . .  .. .. |  || |..    |  |...|...|| ||  ||.....|.||| 
WSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 96280.m00134.AA TyrKc 14-257 22 1.2e-15 30.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

MTFQSVIAKGGFGTIYLVFSLQYQQFFALKKIPENRFNKA---EVDCLMEI--DHPNIISLYKYYKFQ-------EYIYLLMEYCPY-DLETLLKKESE-
 |.  ..  | ||..|.       .  | |.. |.   ..   |   ....  .||||. || .   |       | ....|||.|. ||   |.|  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

ICEDQLKRYCYGILQGIKACHDRNISHSDIKPSNFLIDKYGRIKVCDFGLSVMHFNC--------ADCH----SFR--GTIYFMAPEILCKKGYDSIKAD
.| ..|  .|. | .|    |..|. | |.   | |... ...|..|||||  . .            .    . .    |  |||| . .. . ..| |
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-TTKSD

IWSLGITFFYMATQTFPFNGD------DRKDIIKEVTTGMYPISKVE---------SAALRQVITSCLQIDPLARPTVDDLLNMPFF
.|| |.. . . |   .   .      . ...|. | .|...    .         .... |....| . ||  |||  ..    .|
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 96280.m00134.AA Pkinase_Tyr 54-112 30 0.000148 16.05 Pfam 53-120 (270) Show / Hide 
Range on Protein: 54-112
Range on HMM: 53-120/270
Sequence Identity: 30% (21 aa)

EVDCLMEI-DHPNIISLYKYYK-FQEY--IYLLMEYCPY-DLETLLKK----ESEICEDQLKRYCYGI
|.  .... .||||..||      .|   ||. |||.|. || . |.|    .  ..  .|  .|. |
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQI
Kinase 96280.m00134.AA Pkinase_Tyr 135-150 43 3.526237 1.23 Pfam 143-158 (270) Show / Hide 
Range on Protein: 135-150
Range on HMM: 143-158/270
Sequence Identity: 43% (7 aa)

LIDKYGRIKVCDFGLS
|... . .|.|||||.
LVTENNVVKICDFGLA