Gene 88209.m00070 (T.vaginalis)

88209.m00070

Species: T.vaginalis
Alias: 88209.m00070, TvagK0733
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
88209.m00070.AA Protein None 127 None Fasta, JSON
88209.m00070.kin_dom Protein Kinase Domain None 98 None Fasta, JSON

Protein domain

Protein domains of 88209.m00070.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88209.m00070.AA STE20 1-98 52 3.9e-55 189.5 In-house 182-288 (288) Show / Hide 
Range on Protein: 1-98
Range on HMM: 182-288/288
Sequence Identity: 52% (56 aa)

MVGTPFWMAPELIQR-----TPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIV--TKGIPEISD--KESRSPELLDFLDKCLRKDPKLRPTAEE
.||||.|||||.||.      .| . .||||||| . |.||||||| |..|||| |.|   ... |. .|  ... |||. ||.|||| |||. ||||..
FVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQ

LLNHSFL
||.|.|.
LLKHPFI
Kinase 88209.m00070.AA PAKA 1-98 59 3.8e-54 186.22 In-house 163-260 (260) Show / Hide 
Range on Protein: 1-98
Range on HMM: 163-260/260
Sequence Identity: 59% (58 aa)

MVGTPFWMAPELIQRTPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTKGIPEISDKESRSPELLDFLDKCLRKDPKLRPTAEELLNHSFL
||||| |||||.|.|  |.  ||||||||...|..|||||| .||| || .|| |.|.|.| |... |.|. ||||||| .|.. |..|.|||.| ||
MVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 88209.m00070.AA STE 1-98 36 2.1e-47 163.82 In-house 223-359 (359) Show / Hide 
Range on Protein: 1-98
Range on HMM: 223-359/359
Sequence Identity: 36% (51 aa)

MVGTPFWMAPELIQR------TPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTK---------------GIPEISD----------------
.|||| ||||| ||.       .|.. .||||||... |.|.|.||. |..|||| |.| ..               ..| . |                
FVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTT

-KESRSPELLDFLDKCLRKDPKLRPTAEELLN--HSFL
 ... |||. ||..|||.|||. ||||..||.  |.|.
YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 88209.m00070.AA MST 2-98 54 7e-47 147.0 In-house 158-254 (254) Show / Hide 
Range on Protein: 2-98
Range on HMM: 158-254/254
Sequence Identity: 54% (53 aa)

VGTPFWMAPELIQRTPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTKGIPEISDKESRSPELLDFLDKCLRKDPKLRPTAEELLNHSFL
.|||.||||| ||   |   .||||||| . |.|||.||| |  |||| |.| .| .|  .| |  |.|. ||. ||| |.| .|.|||.||.|.| 
IGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 88209.m00070.AA YSK 1-98 49 3.1e-45 133.92 In-house 159-257 (257) Show / Hide 
Range on Protein: 1-98
Range on HMM: 159-257/257
Sequence Identity: 49% (49 aa)

MVGTPFWMAPELIQR--TPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTKGIPEISDKESRSPELLDFLDKCLRKDPKLRPTAEELLNHSFL
.||||.|||||.|.   . | | .|||||||   |.| ||||| |  |||. |||. .  |. ..... |  . .| . || |||. ||.|.||| |.| 
FVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEGRSY-SKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 88209.m00070.AA PAKB 1-98 52 6.9e-37 128.88 In-house 155-252 (252) Show / Hide 
Range on Protein: 1-98
Range on HMM: 155-252/252
Sequence Identity: 52% (51 aa)

MVGTPFWMAPELIQRTPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTKGIPEISDKESRSPELLDFLDKCLRKDPKLRPTAEELLNHSFL
.||||.|||||.| | ||   ||||||||.  |. .|||||  |||..|   |  .  | ...    ||.| .|||..| .||. | ||.|||.| ||
LVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPPLQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase 88209.m00070.AA PAKL 1-98 46 6.4e-36 125.66 In-house 159-256 (256) Show / Hide 
Range on Protein: 1-98
Range on HMM: 159-256/256
Sequence Identity: 46% (46 aa)

MVGTPFWMAPELIQRTPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTKGIPEISDKESRSPELLDFLDKCLRKDPKLRPTAEELLNHSFL
|.|||.||||| | ...|   .|||||||   |.|.|.||  | |||||   |  .  |  |.    ||.. |||..|. |||  |. . .|| | |.
MIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 88209.m00070.AA Pkinase 2-98 28 1.1e-32 116.64 Pfam 172-293 (293) Show / Hide 
Range on Protein: 2-98
Range on HMM: 172-293/293
Sequence Identity: 28% (35 aa)

VGTPFWMAPELIQ-RTPYSFAVDIWSLGILCRELAEGEPPYVDE-----PPMRATFLIVTKGIPEISDKESRS-------------------PELLDFLD
.|||..||||.|. ...|. .||.||.|... |.. |.||. ..       ... .  . ..... .  ...|                   .|..||..
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

KCLRKDPKLRPTAEELLNHSFL
.||.|||| |||||..|.| ..
WCLCKDPKKRPTAEQILQHPWF
Kinase 88209.m00070.AA FRAY 1-98 41 6.9e-32 96.08 In-house 172-277 (277) Show / Hide 
Range on Protein: 1-98
Range on HMM: 172-277/277
Sequence Identity: 41% (44 aa)

MVGTPFWMAPELIQRTP-YSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTKGIPEISDKESRS-------PELLDFLDKCLRKDPKLRPTAEEL
.|||| ||||| .     | |..||||.||.  ||| | .|| . |||    |.     |     | .        .   . ..||| |||. |||| ||
FVGTPCWMAPEVMEQVHGYDFKADIWSFGITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASEL

LNHSFL
| |.| 
LKHKFF
Kinase 88209.m00070.AA MKC 1-98 44 8e-31 108.72 In-house 161-260 (260) Show / Hide 
Range on Protein: 1-98
Range on HMM: 161-260/260
Sequence Identity: 44% (45 aa)

MVGTPFWMAPELIQRTPYSFAVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVTKGIPE---ISDKESRSPELLDFLDKCLRKDPKLRPTAEELLNHSF
|.| ||||.|| ||  ..| ..||||.||   |.| |.||. .  .| | |.  | |.       |..  |... ||| .||  ||  |||||.|| | |
MCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMANGRPPHHKS-RMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKHPF

L
.
I
Kinase 88209.m00070.AA STE11 1-98 41 1.1e-29 104.58 In-house 195-303 (303) Show / Hide 
Range on Protein: 1-98
Range on HMM: 195-303/303
Sequence Identity: 41% (45 aa)

MVGTPFWMAPELIQRTP---YSFAVDIWSLGILCRELAEGEPPYVDEP--PMRATFLIVTKGIPEISDKESRS------PELLDFLDKCLRKDPKLRPTA
|.|||.||||| | ...   |. ..||||||    | | | ||. .    .| | | |...  | .   |. |      .|. |||..|. .||| ||||
MMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTA

EELLNHSFL
 .||.|.|.
NQLLQHPFI
Kinase 88209.m00070.AA Pkinase_Tyr 6-98 30 1.6e-08 29.49 Pfam 179-270 (270) Show / Hide 
Range on Protein: 6-98
Range on HMM: 179-270/270
Sequence Identity: 30% (29 aa)

FWMAPELIQRTPYSFAVDIWSLGILCRELAE-GEPP-YVDEPPMRATFLI-VTKGIPEISDKESRSPELLDFLDKCLRKDPKLRPTAEELLNHSFL
.||||| |.   .. . |.|| |.|. |.   || | | . .. .   .|    .  ..   |  ..|. | . .| ..||. ||| .|.  |..|
KWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC--PENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase 88209.m00070.AA S_TKc 1-98 14 9e-06 -92.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-98
Range on HMM: 1-231/231
Sequence Identity: 14% (36 aa)

M---------------------------------------------------------------------------------------------------
                                                                                                    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

---------------------------------------------VGTPFWMAPELIQRTPYSF-AVDIWSLGILCRELAEGEPPYVDEPPMRATFLIVT
                                             .|||..||||..   .|.. ..|.||.|..  |.. |.||.     | ..| .. 
YQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG

KGIPEISDKESRSPELLDFLDKCLRKDPKLRPTAEELLN-------HSFL
            |||..||..|||.|||. |||| |.|.       | ..
------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF