Gene 82578.m00484 (T.vaginalis)

82578.m00484

Species: T.vaginalis
Alias: 82578.m00484, TvagK0865
External Links:
Annotation:

Classification

Group: Other
Family: WNK

Sequence

Name Sequence Type Origin Length Description Download
82578.m00484.AA Protein None 330 None Fasta, JSON
82578.m00484.kin_dom Protein Kinase Domain None 195 None Fasta, JSON

Protein domain

Protein domains of 82578.m00484.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82578.m00484.AA WNK 194-268 38 3.9e-19 58.39 In-house 186-261 (261) Show / Hide 
Range on Protein: 194-268
Range on HMM: 186-261/261
Sequence Identity: 38% (29 aa)

DIWGLGIAVLYSTTSEQPYSECTSPYQFIQKLRSFTPPASLQKVQDVYLKNFIEQCLKPTD-QRPTAADLLNHPIF
|.   |  .|   ||| |||||... |   |  .   |.|.||.|.  .|..||.|..     ||....||||  |
DVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTQGIKPNSFQKIQNPEVKEIIEKCIRHNKEERPSIQQLLNHDFF
Kinase 82578.m00484.AA NRBP 23-269 23 3.1e-13 42.58 In-house 3-261 (261) Show / Hide 
Range on Protein: 23-269
Range on HMM: 3-261/261
Sequence Identity: 23% (61 aa)

SVHNNVICFKSFDRENGLEVSWYEVDCQNLND--KQKFALEQRAQVVKGFKKINLLSVFAYW--FNSERTIFYFITESVNSKSV---FDRVKRD-QPLRP
 |    . .   | |.| || | ||.  .. .   |   ..|  . .   .. |.  .  ||   ..|.    |||| . | |.     ..|.. . .. 
DVPGIDCAYLAMDTEEGVEVVWNEVQFSERKNFKAQEEKIRQVFDNLIQLDHQNIVKFHKYWTDTKEEKPRVIFITEYMSSGSMKQFLKKTKKNHKNMNE

RAIVRWLGSVLQALNFLHTQQTPFAHSRIELSSIFIKQSRQVLIPPLLNPAL---LRPTSNQIRIRYTTPPEAL---INQVCPASDIWGLGIAVLYSTTS
.|  ||   .| ||..||. . |  |  .   .|||..   . |      |.   .|   .. |  .  .||      ...  | ||.  |.  |     
KAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGCVWPDAIHHHVRTCREEMRNMHFFAPEYGILEVTDLTTAVDIYSFGMCALEMAVL

EQPYSECTSPYQFIQKLRSFTPPASLQKVQDVYLKNFIEQCLKPT-DQRPTAADLLNHPIFQ
|   | |.        .   .   . . ..|   ..||..||..   .||.| .|| |.|  
EI-QSGCQNGESEY--VTEEAIQRAIHSLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF
S_TKc 82578.m00484.AA S_TKc 15-268 13 4.1e-10 -28.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-268
Range on HMM: 1-231/231
Sequence Identity: 13% (40 aa)

FEKID---------VALSVHNN---VICFKSFDRENGLEVSWYEVDCQNLNDKQKFALEQRAQVVKGFKKINLLSVFAYWFNSERTIFYFITESVNS--K
.|...         | . .|..   .   |  .                        ...  |. |  .  |.   . .. .   . .|...| ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLG

SVFDRVKRDQP------LRPRAIVRWLGSVLQALNFLHTQQTPFAHSRIELSSIFIKQ---------SRQVLIPPLLNPALLRPTSNQIRIRYTTPPEAL
..||. |. ..      . .  . ...  ...||...| .   . |  .  . |.. .         .||.              . ..  ..  .|| |
DLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDEHIKICDFGLARQL--------------TTFCGTPWYMAPEVL

INQVCP-ASDIWGLGIAVLYSTTSEQPYSECTSPYQFIQKLRSFTPPASLQKVQDVYLKNFIEQCLK-PTDQRPTAADLLN-------HPIF
  .  . ..|.| .|. .    . . |..    ... ..|..            .  .|.||..||.   ..|||| ..|.       || |
--GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82578.m00484.AA STE 193-268 20 1.6e-08 26.31 In-house 249-359 (359) Show / Hide 
Range on Protein: 193-268
Range on HMM: 249-359/359
Sequence Identity: 20% (23 aa)

SDIWGLGIAVLYSTTSEQPYSECTSPYQFIQKLRSF-------------TPPASLQKVQD-------------------VYLKNFIEQCLKPTDQ-RPTA
.||| ||. ..   | . |... . ..   ......              || .|.   .                     .|.||..||.   . ||||
CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA

ADLLN--HPIF
 .||.  || .
SQLLKSEHPFI
Kinase 82578.m00484.AA SLK 193-268 30 2.6e-08 24.04 In-house 183-259 (259) Show / Hide 
Range on Protein: 193-268
Range on HMM: 183-259/259
Sequence Identity: 30% (24 aa)

SDIWGLGIAVLYSTTSEQPYSECTSPYQFIQKLRSFTPPASLQKVQ-DVYLKNFIEQCL-KPTDQRPTAADLLNHPIF
.||| ||| ..     | |..|  .|   . |..   ||  .|  .  .  |.|...|| |  ..|.|.|.|..|. .
ADIWSLGITLIEMAQMEPPHHEM-NPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase 82578.m00484.AA PAKB 194-268 35 6.4e-08 25.04 In-house 177-252 (252) Show / Hide 
Range on Protein: 194-268
Range on HMM: 177-252/252
Sequence Identity: 35% (28 aa)

DIWGLGIAVLYSTTSEQPYSECTSPYQFIQKLRSFTPP--ASLQKVQDVYLKNFIEQCL-KPTDQRPTAADLLNHPIF
||| ||| |.     | ||    .| |  ...|   ||    . ||  . |..|....| .   || ||..||.|| .
DIWSLGIMVIEMVDGEPPYFN-EPPLQAMKRIRDMHPPRLKNHHKVS-PRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase 82578.m00484.AA Dicty2 242-268 46 1.5e-07 22.53 In-house 237-264 (264) Show / Hide 
Range on Protein: 242-268
Range on HMM: 237-264/264
Sequence Identity: 46% (13 aa)

LKNFIEQC-LKPTDQRPTAADLLNHPIF
.|.| .||  | . ||.||  ||.||..
CKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase 82578.m00484.AA MST 242-268 42 2.8e-07 19.11 In-house 227-254 (254) Show / Hide 
Range on Protein: 242-268
Range on HMM: 227-254/254
Sequence Identity: 42% (12 aa)

LKNFIEQCL-KPTDQRPTAADLLNHPIF
. .|. .|| |  .||.|| .||.|| .
FNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 82578.m00484.AA Pkinase 191-268 19 3.9e-07 26.3 Pfam 191-293 (293) Show / Hide 
Range on Protein: 191-268
Range on HMM: 191-293/293
Sequence Identity: 19% (20 aa)

PASDIWGLGIAVLYSTTSEQPYSEC-----TSPYQFIQKLRSFTPPASLQKVQD-------------------VYLKNFIEQCLKPT-DQRPTAADLLNH
|..|.|..|. . .  . . |....      ...| |.. ..  .. . ..  .                     .| ||. ||..   .||||...|.|
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PIF
| |
PWF
Kinase 82578.m00484.AA Ste20-DD1 245-268 56 5.8e-07 19.67 In-house 244-268 (268) Show / Hide 
Range on Protein: 245-268
Range on HMM: 244-268/268
Sequence Identity: 56% (14 aa)

FIEQCL-KPTDQRPTAADLLNHPIF
|| ||| .  | || | .|||||  
FIKQCLNMNPDKRPSAQQLLNHPFI
Kinase 82578.m00484.AA ASK 191-268 26 7.3e-07 18.66 In-house 176-254 (254) Show / Hide 
Range on Protein: 191-268
Range on HMM: 176-254/254
Sequence Identity: 26% (21 aa)

PASDIWGLGIAVLYSTTSEQPYSECTSPYQFIQKLRSFTPPASLQKVQDVYLKNFIEQCLKP-TDQRPTAADLLNHPIF
.. ||| .|  ..   |.  |. |  .|   . |   .     . .      |||| .| .|  ..|..|.|||. |  
KPADIWSFGCTMVEMATGKPPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase 82578.m00484.AA STE11 190-268 22 9.4e-07 20.75 In-house 216-303 (303) Show / Hide 
Range on Protein: 190-268
Range on HMM: 216-303/303
Sequence Identity: 22% (20 aa)

CPASDIWGLGIAVLYSTTSEQPYSECTS-PYQFIQKLRSF-TPPAS-LQKVQD-----VYLKNFIEQCLKPTDQ-RPTAADLLNHPIF
. ..||| ||  |.   |   |...... ... . |  .. .|.    ....        ...|. .|...  . ||||..||.|| .
GRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase 82578.m00484.AA WNK 31-140 25 2e-06 16.66 In-house 16-128 (261) Show / Hide 
Range on Protein: 31-140
Range on HMM: 16-128/261
Sequence Identity: 25% (29 aa)

FKSFDRENGLEVSWYEVDCQNLNDKQKFALEQRAQVVKGFKKINLLSVFAYWFNS---ERTIFYFITESVNSKSVFDRVKRDQPLRPRAIVRWLGSVLQA
.. .| | . || | |.  | |.   .  .   |.  |. .. | .. . ||  .    .     .||   |       || . ..|.   .|   .|. 
YRGLDTETWVEVAWCELQDQKLSKNERQRFKEEAEMLKKLQHPNIVRFYDYWESVLCGKK-CIVLVTELMTSGTLKTYLKRFKKMKPKVLRSWCRQILKG

LNFLHTQQT-PFAH
|.||||.|  |  |
LHFLHTRQPHPIIH
Kinase 82578.m00484.AA TyrKc 34-268 13 0.000464 -156.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-268
Range on HMM: 1-280/280
Sequence Identity: 13% (39 aa)

FDRENGLEV---------SWYEVDC---QNLNDKQKFALEQRAQVVKGF--KKINLLSVFAYWFNSER-----TIFYFITESVNSKSVFDRVKRDQP-LR
   .  |            |. ...      .|. . .. . |.. . .  .  |..  ...   ..|        . ..| .   .  |. .. .| | 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

PRAIVRWLGSVLQALNFLHTQQTPFAHSRIELSSIFIKQSRQV---------LIPPL----LNPALLRP----TSNQ-IRIRYTTPPEALINQVC-PASD
..  . .   . .  ..|| .  .. |  .    . ..  ..|          |        .    |.     ..  . ||  ..||..   .. ..||
MKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW-MAPECINYGKFTTKSD

IWGLGIAVLY--STTSEQPYSEC----TSPYQFIQKLRSF-TPPASLQ--------KVQDVYLKNFIEQCLKP-TDQRPTAADLLNHPIF
.|  |. ...   |  .|||..      |... |.....   .|              ...|    ..|| .   ..||| ...  | .|
VWSFGV-CMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRPTFSEI--HECF
Kinase 82578.m00484.AA Pkinase 73-132 14 0.005719 11.58 Pfam 63-125 (293) Show / Hide 
Range on Protein: 73-132
Range on HMM: 63-125/293
Sequence Identity: 14% (10 aa)

INLLSVFAYWFNSERTIFYFITESVNSK----SVFDRVK--RDQPL--RPRAIVRWLGSVLQALNFLH
. |. .| .     ..  |...| ..      . ||...  |. ..   .. . ...  .|..|...|
VRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCH
Kinase 82578.m00484.AA PAKB 123-134 66 0.350968 0.35 In-house 103-114 (252) Show / Hide 
Range on Protein: 123-134
Range on HMM: 103-114/252
Sequence Identity: 66% (8 aa)

SVLQALNFLHTQ
.||||| .|| |
QVLQALAYLHAQ