Gene 94472.m00077 (T.vaginalis)

94472.m00077

Species: T.vaginalis
Alias: 94472.m00077, TvagK0947
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94472.m00077.AA Protein None 493 None Fasta, JSON
94472.m00077.kin_dom Protein Kinase Domain None 208 None Fasta, JSON

Protein domain

Protein domains of 94472.m00077.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94472.m00077.AA Ciliate-E2 252-473 20 1.9e-39 133.06 In-house 45-365 (365) Show / Hide 
Range on Protein: 252-473
Range on HMM: 45-365/365
Sequence Identity: 20% (69 aa)

VISKISAKSQTNDTQIQAEIEANKITK-------------------HRNVMKMIALLE--DELFWYILWPDTDGYTLKDLISNQ-----------KNIIE
| .|| |. . .  ||..    ..| .                   | |..||.   .  |.   |.     .| .|.|.| |.           |.. |
VKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTE

EAARPIFRQMML---------------ALQHIHSCD-IVLNNITPKTIVFYKNTVRFTNFSTCRFAEKS-------------------------------
. .. |..|                  ||...||   |.  .| |  |.|    .  . | ..... ..                               
KEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQ

-DMNETYFLRTPYASPESFTKKPYNG--------MLSDIWSCGVILYEMLSGKYPFGGSSHEQFAEKVKKGNVIYPKA------------------FSSQ
 .|  |.    .| .|| . .|.|..          .||||.||||||||.||.||         .. |.... .|..                   | .
QNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQE

VIQLLKG----IFSTVPSERFS-IEQILSHPWL
...|.|     ..   |..|.. .|||| |||.
CKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94472.m00077.AA CAMKL 383-473 34 1.5e-35 110.79 In-house 198-297 (297) Show / Hide 
Range on Protein: 383-473
Range on HMM: 198-297/297
Sequence Identity: 34% (35 aa)

PYASPESFTK--KPYNGMLSDIWSCGVILYEMLSGKYPFGGSSHE-------QFAEKVKKGNVIYPKAFSS-QVIQLLKGIFSTVPSERFSIEQILSHPW
||..|| | .  |||.|   |||||||||| |. |..|| . ...        . .|...|   .|. ..  ....|....  . |..|..|.||..|||
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPW

L
.
M
Kinase 94472.m00077.AA CAMK 383-473 27 2.6e-34 107.42 In-house 284-425 (425) Show / Hide 
Range on Protein: 383-473
Range on HMM: 284-425/425
Sequence Identity: 27% (39 aa)

PYAS-PESFTK-------------KPYNGMLSDIWSCGVILYEMLSGKYPFGGS-------------SHEQFAEKVKKGNVI-YPKAFSS----------
.|.. || . .             ||| |  .|.|||||||| ||.|..|| |.             . ..  ||..||.   .|. ||           
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWW

-------------QVIQLLKGIFSTVPSERFSIEQILSHPWL
             ....|....  . |..|..|||.|.|||.
DDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94472.m00077.AA MARK 383-473 39 2.2e-33 106.6 In-house 170-262 (262) Show / Hide 
Range on Protein: 383-473
Range on HMM: 170-262/262
Sequence Identity: 39% (37 aa)

PYASPESFTKKPYNGMLSDIWSCGVILYEMLSGKYPFGGSS--HEQFAEKVKKGNVIYPKAFSSQVIQLLKGIFSTVPSERFSIEQILSHPWL
||..|| | ||||.|   ||||.||.|| |..|..|| |..   ..  .|. .|.  .|   | .  .|.. .. . |.|| .||.|..|||.
PYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 94472.m00077.AA Ciliate-E2-Unclassified 248-473 19 4e-32 108.72 In-house 23-352 (352) Show / Hide 
Range on Protein: 248-473
Range on HMM: 23-352/352
Sequence Identity: 19% (66 aa)

TKGLV-------ISKISAKSQT---NDTQIQAEIEANKI------------------TKHRNVMKMIALLEDELFWYILWPDTDGYTLKDLISNQKN---
.| ..        ..| .. |    .   .. ..| |..                   .| ...||.   .|.   ||     .| .|.. |...|.   
QK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQ

--------------IIEEAAR-----PIFRQMMLALQHIHSCD-IVLNNITPKTIVFYKN----TVRFTNFSTCRFAEKS---------------DMNET
              . |..|.      .|.|  ..|...|.   |.  .|.|  |.| .|     .. . |. ... ...               ... .
KGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMW

YFLRTPY-A----SPESFTKKPYNGM---LSDIWSCGVILYEMLSGKYPFGGSSHEQ----------------FAEKVKKGNVIYPK--------AFSSQ
 |  ||.      .|| . .. |...    .||||.|||||||| |.|||.. . ||                . .. |..|. .||          | .
TFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPE

VIQLLK----GIFSTVPSERFSIEQILSHPWL
.. ...     ..   |..| ..|||| |||.
AKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94472.m00077.AA AMPK 384-473 41 4.4e-31 89.58 In-house 165-254 (254) Show / Hide 
Range on Protein: 384-473
Range on HMM: 165-254/254
Sequence Identity: 41% (37 aa)

YASPESFTKKPYNGMLSDIWSCGVILYEMLSGKYPFGGSSHEQFAEKVKKGNVIYPKAFSSQVIQLLKGIFSTVPSERFSIEQILSHPWL
||.||  . |.|.|   |||||||||| || |. ||  ..  .   |.|.| .  || .|... .|.|..  . | .|..|..|  |||.
YAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 94472.m00077.AA GIN4 257-473 27 2.1e-28 87.47 In-house 71-293 (293) Show / Hide 
Range on Protein: 257-473
Range on HMM: 71-293/293
Sequence Identity: 27% (61 aa)

SAKSQTNDTQIQAEIEANKITKHRNVMKMIALLEDELFWYILWPDTDGYTLKDLISNQKNIIEEAARPIFRQMMLALQHIHSCDIVLNNITPKTIVF-YK
| ..|||   |  ||   |.  | |||..    | .   |..    ..  | ... ..  . |  |  .|||..  .   |. .|.   . |  ..   |
SNHDQTNPYGIEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHK

NT-VRFTNFSTCRFAEKSDMNETYFLRTPYASPESFTKKPYNGMLSDIWSCGVILYEMLSGKYPFGGS--SHEQFAEKVKKGNVIYPKA--FSSQVIQLL
.  ..   |       .... ||      ||.||     ||.|  ||.|||||||. .| |. ||        .   ||.||.   |     |..   |.
YNRIKIADFGMAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLI

KGIFSTVPSERFSIEQILSHPWL
. |    |  |  . .||.|| .
RKILVVDPEKRIKTRDILKHPLI
Kinase 94472.m00077.AA MELK 266-473 26 9.8e-28 91.62 In-house 43-254 (254) Show / Hide 
Range on Protein: 266-473
Range on HMM: 43-254/254
Sequence Identity: 26% (56 aa)

QIQAEIEANKITKHRNVMKMIALLEDELFWYILWPDTDGYTLKDLISNQKNIIEEAARPIFRQMMLALQHIHSCDIVLNNITPKTIVFYKNT-VRFTNFS
....|..| |  .|... ..  ..| |   ...     |  . | |  |. . || .| .|||.. |. ..||      .. |  ..|  .  ... .| 
RVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFG

TC-RFAEKSDMN--ETYFLRTPYASPESFTKKPYNGMLSDIWSCGVILYEMLSGKYPFGGSSHEQFAEKVKKGNVIYPKAFSSQVIQLLKGIFSTVPSER
 | .   . |    .|      || ||    | | |   |.|| |..|| .. |  ||     . .  |. .|    ||  | . .|||. .   .|  |
LCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKR

FSIEQILSHPWL
 |. ..| |||.
ISMKNLLNHPWV
Kinase 94472.m00077.AA TSSK 384-473 31 3e-23 73.14 In-house 194-289 (289) Show / Hide 
Range on Protein: 384-473
Range on HMM: 194-289/289
Sequence Identity: 31% (30 aa)

YASPESFTKKPYNGMLSDIWSCGVILYEMLSGKYPFGG--SSHEQFAEKVKKGNVIYPK----AFSSQVIQLLKGIFSTVPSERFSIEQILSHPWL
||.|| .  .||.....|.||.||||| |. |. ||    | . .  . ..  .|..||    . |.. . |.. . .  |..| .|..|..|.|.
YAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase 94472.m00077.AA ULK 384-473 27 1.7e-22 75.42 In-house 217-329 (329) Show / Hide 
Range on Protein: 384-473
Range on HMM: 217-329/329
Sequence Identity: 27% (31 aa)

YASPESFT----KKPYNGMLSDIWSCGVILYEMLSGKYPFGGS--SHE-----QFAEK-------VKKGNVIYPKA-----FSSQVIQLLKGIFSTVPSE
| .|. .     .|||.   .|||| |.|.|||| ||.|| ..  .       .  ..       .|| .  .||.     .|.....|... .   ...
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKD

RFSIEQILSHPWL
|.|.|....|||.
RISWEELFNHPWF
Kinase 94472.m00077.AA Pkinase 383-473 26 6.7e-22 78.51 Pfam 176-293 (293) Show / Hide 
Range on Protein: 383-473
Range on HMM: 176-293/293
Sequence Identity: 26% (31 aa)

PYASPESFTKKPYNGMLSDIWSCGVILYEMLSGKYPFGGS------SHEQFAEKVKKGNVIYPKAFS---------------------SQVIQLLKGIFS
.|..||   . .| |  .|.||||.||||||.|. || |.      .. |  ...... . ..   .                     .  ....|... 
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

TVPSERFSIEQILSHPWL
  |..| ..|||| |||.
KDPKKRPTAEQILQHPWF
S_TKc 94472.m00077.AA S_TKc 231-473 23 2.6e-18 68.1 SMART 10-231 (231) Show / Hide 
Range on Protein: 231-473
Range on HMM: 10-231/231
Sequence Identity: 23% (60 aa)

GCMVSVTSATPNLVKEPTKGLVISKISAKSQTNDTQIQAEIEANKITKHRNVMKMIALLEDELFWYILWPDTDG--YTLKDLISNQKN------IIEEAA
| . .|  .. .     |. .|  ||         .|. ||.  |  .| |. |..   .|  . |.     ||   .|.|.| ...       . |  |
GAFGKVYKCRHKK----TGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

RPIFRQMMLALQHIHSCDIVLNNITPKTIVFYKNTVRFTNFSTCRFAEKSDMNETYFLRTPYASPESFTKKPYNGMLSDIWSCGVILYEMLSGKYPFGGS
| ...|. .||...||  |.   . |  | . . ..  . |  .|.        |.     | .|| .   .|..  .|.||||.||||||.|. ||   
RFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--

SHEQFAEKVKKGNVIYPKAFSSQVIQLLKGIFSTVPSERFSIEQILS-------HPWL
 ...  .|..          |...........   |..| .. ..|        |||.
QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94472.m00077.AA CAMKL 259-342 25 3e-08 22.29 In-house 52-149 (297) Show / Hide 
Range on Protein: 259-342
Range on HMM: 52-149/297
Sequence Identity: 25% (25 aa)

KSQTNDTQIQAEIEANKITK---HRNVMKMIALLEDELF------WYILWPDTDGYT--LKDLISNQKN----IIEEAARPIFRQMMLALQHIHSCDIV
|.....  |. ||.  |  .   | |..|.   .|.. .       |.     .|    | | | ....    . |. || .|||.. |....||..||
KHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIV
Kinase 94472.m00077.AA TSSK 319-342 50 4.1e-07 19.38 In-house 122-145 (289) Show / Hide 
Range on Protein: 319-342
Range on HMM: 122-145/289
Sequence Identity: 50% (12 aa)

EEAARPIFRQMMLALQHIHSCDIV
|| ||  ||||  |....||...|
EEQARKWFRQMVSAVKYCHSHNVV
Kinase 94472.m00077.AA CAMK 319-342 45 2e-06 15.77 In-house 178-201 (425) Show / Hide 
Range on Protein: 319-342
Range on HMM: 178-201/425
Sequence Identity: 45% (11 aa)

EEAARPIFRQMMLALQHIHSCDIV
|. || .|||.  |....||..||
EREARRYFRQICSAVHYCHSHNIV
Kinase 94472.m00077.AA Pkinase 251-342 22 1e-05 21.31 Pfam 26-130 (293) Show / Hide 
Range on Protein: 251-342
Range on HMM: 26-130/293
Sequence Identity: 22% (24 aa)

LVISKISAKSQTNDTQIQA-----EIEANKITKHRNVMKMIALLEDELFWYILWPDTDGY----TLKDLIS--NQKNI--IEEAARPIFRQMMLALQHIH
.|  ||  |. ... . |.     ||.  |  .| |. ...   ||.   |.  .  .|      |.|.||  .....   |. .. ...|.  .|...|
IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCH

SCDIV
|. |.
SMGII
Kinase 94472.m00077.AA TyrKc 251-473 14 2e-05 -135.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 251-473
Range on HMM: 1-280/280
Sequence Identity: 14% (42 aa)

LVISKI---------------------SAKSQTNDTQIQAEIEANKIT--KHRNVMKMIALLEDE-------LFWYILWPDTDGYTLKDLISNQKNIIEE
..  |.                     . |. .    .  |..  .    .| |. ....   ..          .|.    ..  ||| . . ..    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK---

AARPIFRQMML----ALQHIHSCDIV------------LNNITPKTIVFYKNTVRFTNFSTCRFAEKSDMN----ETYF------LR--TPYA--SPESF
   . . ....      ...||  ..             |.           ||. . |  .|. .  |..    ..|        .   |.   .||..
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

TKKPYNGMLSDIWSCGVILYEMLS-GKYPFGG-----SSHEQFAEKVKKGNVIYPKAF---------SSQVIQLLKGIFSTVPSERFSIEQILSHPWL
 .. ..   ||.|| || ..|... |. |  |      | ..  |.||.|.   . .          .. . |. |      |..| . ..|  |  .
NYGKFT-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94472.m00077.AA ULK 252-342 17 2.3e-05 14.79 In-house 32-152 (329) Show / Hide 
Range on Protein: 252-342
Range on HMM: 32-152/329
Sequence Identity: 17% (21 aa)

VISKISAKSQTNDT----------QIQAEIEANKITK--------HRNVMKMIALLEDELF--WYILWPDTDGYTLKDLIS----------NQKNIIEEA
.. .|. ... ..           ... ||.  |  |        | |. |..  .|.  .  .||     .| .|...|.          ..|.. |. 
ACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQE

ARPIFRQMMLALQHIHSCDIV
|. .|.| . .....|.  |.
AIQFFKQILNGFKELHKHNII
Kinase 94472.m00077.AA Pkinase_Tyr 400-435 35 0.000566 14.08 Pfam 195-233 (270) Show / Hide 
Range on Protein: 400-435
Range on HMM: 195-233/270
Sequence Identity: 35% (14 aa)

SDIWSCGVILYEMLS-GKYP-FGGSSHEQFAEKV-KKGN
||.|| || ..|... |. | . | | |.. |.. ..|.
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase 94472.m00077.AA MARK 319-342 54 0.011358 4.75 In-house 103-126 (262) Show / Hide 
Range on Protein: 319-342
Range on HMM: 103-126/262
Sequence Identity: 54% (13 aa)

EEAARPIFRQMMLALQHIHSCDIV
|| || ||||.  |..  || .||
EEEARRIFRQIVSAVNYCHSKNIV