Gene 90463.m00062 (T.vaginalis)

90463.m00062

Species: T.vaginalis
Alias: 90463.m00062, TvagK0209
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
90463.m00062.AA Protein None 249 None Fasta, JSON
90463.m00062.kin_dom Protein Kinase Domain None 190 None Fasta, JSON

Protein domain

Protein domains of 90463.m00062.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90463.m00062.AA Ciliate-E2-Unclassified 10-191 20 7.3e-29 97.26 In-house 93-352 (352) Show / Hide 
Range on Protein: 10-191
Range on HMM: 93-352/352
Sequence Identity: 20% (54 aa)

KNFVYILMECCPS---EFYSHNTKK---------------ISLNSDQLK-----KYCYEILCAIKMFHDRG-ISHTDLKPSNFMIDQNG---KVKLCQAS
|. .|| || |.    ..|  . ||                 .   | |     .|...||....  |  . | | |.||.| ..|.||   ..|..  .
KQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFG

IASLYERDIQQIDYR-----------------DFMLFM----SPEVLKRKAYDPM---KADIWAVGITFYYIFLHIHPFFADNFKT--------------
|.. |. ....  ..                     .|    .||||... || .   |.|||..|. .|..    .||.. | .               
ISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

--LIKLVNDGIFPIFA--------IKDPQFRDVIN----RCLDYCEETRASVDELLNMPYF
  |..  ..... ..         . .|.  | ||    ..|... . | . ...|| |.|
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 90463.m00062.AA Ciliate-E2 1-191 15 6.9e-22 71.9 In-house 95-365 (365) Show / Hide 
Range on Protein: 1-191
Range on HMM: 95-365/365
Sequence Identity: 15% (44 aa)

MQVYKYYR--YKNFVYILMECCPS-EFYS------HNTKKI-----SLNSDQLKKYCYEILC---------------AIKMFHDRG-ISHTDLKPSNFMI
.. | ..    .| .|. || |   . ..      .. ...     ...  . |.. ..||                |..  | .. | | |.||.| ..
IKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

DQNGKVKLCQASIASLYERDIQQIDYRD----------------------------------FMLFMSPEVLKRKAYDP--------MKADIWAVGITFY
     .|..   ..  |  |........                                     .|.||.|..| ||          |.|||..|...|
-----IKIIDFGLSKKY--DDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

YIFLHIHPFFADNFKTLIKLVNDGIFPIFAIK------------------DPQFRDVINR----CLDYCEETRAS-VDELLNMPYF
.     .||        ..   .. . ..  .                  ...  | |..    .|.. .| | .  ...|| |.|
EMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 90463.m00062.AA STE 4-191 19 7.2e-19 63.36 In-house 96-359 (359) Show / Hide 
Range on Protein: 4-191
Range on HMM: 96-359/359
Sequence Identity: 19% (52 aa)

YKYYRYK-------NFVYILMECCP----SEFYSHN-TKKISLN----------SDQLKKYCYEILCA-IKMFHDRGISHTDLKPSNFMIDQNGKVKLC-
| .| ..       . ..| || ..    .... |.  .. .||           .|....|..|| .  .  |. .| | |.||.| ..     |||| 
YGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCD

-------QASIASL---------YERDIQQIDYRDFMLFMSPEVLKR------KAYDPMKADIWAVGITFYYIFLHIHPFFADNFKTLIKLVNDGI----
       . |.|..         . .. .         .|.|||...      | ||  |.||| .|.|        .|..  .    . . ....    
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

---------FPIFAIKD----------------------PQFRDVINRCLDYCEETRASVDELLN--MPYF
         .|.  ..|                      | |.| ||.||..  . |.....||.   | .
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 90463.m00062.AA ULK 101-191 31 1e-18 62.02 In-house 216-329 (329) Show / Hide 
Range on Protein: 101-191
Range on HMM: 216-329/329
Sequence Identity: 31% (36 aa)

LFMSPEVLK----RKAYDPMKADIWAVGITFYYIFLHIHPFFADNFKTLI-----KLVNDG--------IFPIFAIK-------DPQFRDVINRCLDYCE
|.|.|..|.    .| |.  |.||| .|. ||..     ||.|  | ...     ||.|..         .|.   |        |...| | |.| | |
LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDE

ETRASVDELLNMPYF
. | | .||.|.| |
KDRISWEELFNHPWF
Kinase 90463.m00062.AA ULK 101-191 32 2.8e-18 61.49 In-house 212-324 (324) Show / Hide 
Range on Protein: 101-191
Range on HMM: 212-324/324
Sequence Identity: 32% (37 aa)

LFMSPEVLK----RKAYDPMKADIWAVGITFYYIFLHIHPFFADNFKTLI----KLVNDG--------IFPI-FAIKD------PQFRDVINRCLDYCEE
|.|.|..|.    .| |.  |.||| .|. ||..     |||.. | ...    ||.| |          || | ...      |...| | |.| | |.
LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEK

TRASVDELLNMPYF
 | | .|..|.| |
DRISWEEIFNHPWF
Kinase 90463.m00062.AA MELK 2-191 24 7.1e-18 57.39 In-house 61-254 (254) Show / Hide 
Range on Protein: 2-191
Range on HMM: 61-254/254
Sequence Identity: 24% (49 aa)

QVYKYYRYKNFVYILMECCP-SEFYSHNTKKISLNSDQLKKYCYEILCAIKMFHDRGISHTDLKPSNFMIDQNGKVKLCQASIASLYERDIQQIDYR---
|.| |   .. ....|| ||  |.. .  ..  |. .. ...  .|. ||   | .| .| |||| |...|.. ..||    . .       ..||    
QLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT---KGRKDYHNLQ

---DFMLFMSPEVLKRKAYDPMKADIWAVGITFYYIFLHIHPFFADNFKTLIKLVNDGIFPIFAIKDPQFRDVINRCLDYCEETRASVDELLNMPYF
     . .  ||... | |    ||.|..||  | ..  . ||  || . . | .  |..       |. .... . |    . | |. .||| |. 
TCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 90463.m00062.AA Pkinase 102-191 17 2.1e-17 62.62 Pfam 177-293 (293) Show / Hide 
Range on Protein: 102-191
Range on HMM: 177-293/293
Sequence Identity: 17% (21 aa)

FMSPEVLKRKAYDPMKADIWAVGITFYYIFLHIHPFFAD------NFKTLIKLVNDGIFPIFAIKD---------------------PQFRDVINRCLDY
.|.|||..   |.. |.|.|..|...|. ..   ||  .      . . .|... .....    ..                     . ..|.|..||..
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

CEETRASVDELLNMPYF
. . | . ...|. |.|
DPKKRPTAEQILQHPWF
Kinase 90463.m00062.AA CAMK 102-191 19 2.5e-16 48.42 In-house 285-425 (425) Show / Hide 
Range on Protein: 102-191
Range on HMM: 285-425/425
Sequence Identity: 19% (27 aa)

FMS-PEVLKR-------------KAYDPMKADIWAVGITFYYIFLHIHPFFAD-------------NFKTLIKLVNDGIF--PIFAIKD-----------
.|. ||||..             | |.. |.|.|..|.  |       || .|             | . | . .  | .  | . ...           
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

-----------PQFRDVINRCLDYCEETRASVDELLNMPYF
           .. .| |...| .  | |..... || | .
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 90463.m00062.AA Pkinase 2-79 28 1.3e-15 56.3 Pfam 64-154 (293) Show / Hide 
Range on Protein: 2-79
Range on HMM: 64-154/293
Sequence Identity: 28% (26 aa)

QVYKYYRYKNFVYILMECCPS-----EFYSHNT--KKISL--NSDQLKKYCYEILCAIKMFHDRGISHTDLKPSNFMIDQNGKV----KLC
. | ....|. .|. ||.|.      . ... .  .. ..    ...|.|.|.||....  |..|| | ||||.|..||.|| .    |.|
RLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC
Kinase 90463.m00062.AA CAMKK 102-191 23 1.6e-15 45.26 In-house 276-396 (396) Show / Hide 
Range on Protein: 102-191
Range on HMM: 276-396/396
Sequence Identity: 23% (28 aa)

FMSPEVLKR-KA--------------YDPMKADIWAVGITFYYIFLHIHPFFADN-FKTLI---KLVNDGI-FPIF-----------AIKDPQFRDVINR
|| ||.. . .               |.  .|||||.|.|.|... .  ||...| ....    | .|| | ||..               ... |.|.|
FMAPELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKR

CLDYCEETRASVDELLNMPYF
.|.  ...| ....... | .
MLEKNPTKRITIPQIKVHPWV
Kinase 90463.m00062.AA S_TKc 2-191 21 1.7e-14 35.68 SMART 14-231 (231) Show / Hide 
Range on Protein: 2-191
Range on HMM: 14-231/231
Sequence Identity: 21% (53 aa)

QVYKYYRYK-------------------------------------NFVYILMECCPS---EFYSHNTKKIS------LNSDQLKKYCYEILCAIKMFHD
.||| .  |                                     ...|. ||.|.    . ...  |. .      ..  . ..|.|.|.||..  |.
KVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHS

RGISHTDLKPSNFMIDQNGKVKLCQASIASLYERDIQQIDYRDF---MLFMSPEVLKRKAYDPMKADIWAVGITFYYIFLHIHPFFADNFKTLIKLVNDG
.|| | ||||.| ..|.   .|.|   .| ..         . |     .|.||||    |.. |.|.|..|...|  .    ||   . ....|..   
HGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--

IFPIFAIKDPQFRDVINRCLDYCEETRASVDELLN-------MPYF
        .|...| |..||..  | | .. |.|.       .|.|
--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90463.m00062.AA CAMKL 102-191 24 1.2e-11 33.33 In-house 199-297 (297) Show / Hide 
Range on Protein: 102-191
Range on HMM: 199-297/297
Sequence Identity: 24% (25 aa)

FMSPEVLKR--KAYDPMKADIWAVGITFYYIFLHIHPFFADNFK---------TLIKLVNDGIFPIFAIKDPQFRDVINRCLDYCEETRASVDELLNMPY
.|.||....  | ||  |.|||. |.. | .     || .|. .          ... .  . .||.   . . || | . |  . | |.......| | 
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase 90463.m00062.AA CAMK 9-79 15 5.7e-10 27.58 In-house 119-238 (425) Show / Hide 
Range on Protein: 9-79
Range on HMM: 119-238/425
Sequence Identity: 15% (19 aa)

Y---------KNFVYILM---ECCPS-----EFYSHNTKK---------------ISLNSDQLKKYCYEILCAIKMFHDRGISHTDLKPSNFMIDQN---
|         ....|. |   | |.      . ... ...                 .. .. ..|   |..|..  |...| | |||| | ..|.|   
YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDD

--------------GKVKLC
              ...|..
SDPVEHDEIFDWNNNNIKII
Kinase 90463.m00062.AA MARK 102-191 30 8.8e-10 28.33 In-house 171-262 (262) Show / Hide 
Range on Protein: 102-191
Range on HMM: 171-262/262
Sequence Identity: 30% (28 aa)

FMSPEVLKRKAYDPMKADIWAVGITFYYIFLHIHPFFADN--FKTLIKLVNDGIFPIFAIKDPQFRDVINRCLDYCEETRASVDELLNMPYF
.|.||....| ||  |.|||. |.  |..     || .|.  .|.| | .. | ..|.    .. |. |.| |    | |....|... | .
YMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 90463.m00062.AA MARK 40-79 33 2.6e-09 26.76 In-house 107-148 (262) Show / Hide 
Range on Protein: 40-79
Range on HMM: 107-148/262
Sequence Identity: 33% (14 aa)

KKYCYEILCAIKMFHDRGISHTDLKPSNFMIDQNG--KVKLC
....  |..|..  |...| | |.|| | .||.||  ..|..
RRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKII
Kinase 90463.m00062.AA CAMKL 1-79 22 8.8e-09 23.99 In-house 78-171 (297) Show / Hide 
Range on Protein: 1-79
Range on HMM: 78-171/297
Sequence Identity: 22% (21 aa)

MQVYKYYRYKNF------VYILMECCPSE---FYSHNTKK----ISLNSDQLKKYCYEILCAIKMFHDRGISHTDLKPSNFMIDQNG--KVKLC
.. |  .  ...      .|. || |..     . .  |.     ..  .. ..|   |..|..  |..|| | |.|| | ..|.||  ..|..
IKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKII
Kinase 90463.m00062.AA CAMKK 22-79 17 2.5e-07 18.82 In-house 136-241 (396) Show / Hide 
Range on Protein: 22-79
Range on HMM: 136-241/396
Sequence Identity: 17% (19 aa)

SEFYSHNTKKI-----SLNSDQ---------------------LKKYCYEILCAIKMFH-DRG-------------------ISHTDLKPSNFMIDQNG-
.| || |...      .....|                     ..||  .......  | ...                   | | |.||.|  ||..| 
TELYS-NRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGC

--KVKLC
  .||..
GEHVKIA
Kinase 90463.m00062.AA ULK 2-79 23 9e-06 16.58 In-house 79-180 (324) Show / Hide 
Range on Protein: 2-79
Range on HMM: 79-180/324
Sequence Identity: 23% (24 aa)

QVYKYYRYK--NFVYILMECCPS---EFYSHNTKK-------ISLNSDQLKKYCYEILCAIKMFHDRGISHTDLKPSNFMIDQ-NGK-----------VK
. |.... .  |..|| || |.    | | .. ||         |. .. ..... |. . |. |...| | |.||.| .|   ..|           .|
KLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLK

LC
..
IA
Kinase 90463.m00062.AA ULK 2-79 24 2e-05 15.03 In-house 82-184 (329) Show / Hide 
Range on Protein: 2-79
Range on HMM: 82-184/329
Sequence Identity: 24% (25 aa)

QVYKYYRYK--NFVYILMECCPS---EFYSHNTKK--------ISLNSDQLKKYCYEILCAIKMFHDRGISHTDLKPSNFMIDQ-NGK-----------V
. |.... .  | .|| || |.    | | .. ||          |. .. ..... || . |. |...| | |.||.| .|.  ..|           .
KLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVL

KLC
|..
KIA