Gene 80474.m00072 (T.vaginalis)

80474.m00072

Species: T.vaginalis
Alias: TvagK0140, 80474.m00072
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
80474.m00072.AA Protein None 264 None Fasta, JSON
80474.m00072.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of 80474.m00072.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80474.m00072.AA CAMK 2-198 20 2.4e-52 166.58 In-house 94-425 (425) Show / Hide 
Range on Protein: 2-198
Range on HMM: 94-425/425
Sequence Identity: 20% (69 aa)

RIDDPRIVRLYQIYRY-------------------NDFIYMVM---EYCPT-----DLYKVFSAG---------------GKLYEEDIYRYAHDAVLAIK
..| | |..||..|                     ....||||   |||.      ||.    .                |.. |..  || .  . |..
KLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVH

SVHDKNIAHCDIKPANFFIDTY-----------------GRVKIGDFGLA--SFNGSSCS----------------------CKMAKGTKLFMA-PEVYC
  |..||.|.|.|| |  .|.                  . .|| |||.|   . |...                       .|   ||  .|| |||  
YCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLN

K--------------KYTPMKSDIWSLGVTLYFLATQTYPFNAP-------------DIEKLKQCISIGLF--ATDKVQN--------------------
.              .| . |.|.||.|| ||.. . ..||...             ....|.. |  | .    ... .                    
GKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHF

--KNLLAVISKCLDRDPEKRPTADEILQMPYF
  .     |.|.| .|||||.|....|. | .
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 80474.m00072.AA Pkinase 6-198 30 2.3e-50 178.46 Pfam 60-293 (293) Show / Hide 
Range on Protein: 6-198
Range on HMM: 60-293/293
Sequence Identity: 30% (72 aa)

PRIVRLYQIYRYNDFIYMVMEYCPT-----DLYKVFS--AGGKL--YEEDIYRYAHDAVLAIKSVHDKNIAHCDIKPANFFIDTYGRV----KIGDFGLA
| ||||| .....| ||||||||.      ||. . |  ..|..   |... .|.   . ...  |...| |.|.||.|..||  | .    ||.|||||
PNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA

SF--NGSSCSCKMAKGTKLFMAPEVYC-KKYTPMKSDIWSLGVTLYFLATQTYPFNAP----DIEKLKQCISIGLFATDKVQN-----------------
 .  . ..  ..   ||  .|||||    .| . |.|.||.|..|| ...   ||       .    .|.|   . .  . .                  
KQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFH

-------KNLLAVISKCLDRDPEKRPTADEILQMPYF
       .... .|..||..||.|||||..||| |.|
WTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80474.m00072.AA AGC 4-198 21 6.1e-48 120.9 In-house 88-395 (395) Show / Hide 
Range on Protein: 4-198
Range on HMM: 88-395/395
Sequence Identity: 21% (68 aa)

DDPRIVR-LYQIYRYNDF--IYMVMEYCP---------TDLYKVFSAGG-----KLYEEDIYRYAHD-------AVLAIKSVHD-KNIAHCD-IKPANFF
. | ||. |.  .  .|   .|.||||.|          ..   ..  |     .. || .  ||          |||. . |. ..| | | .|| |  
HHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENIL

IDTYGRVKIGDFGLASFNGSSC---------------------------------------------------SCKMAKG--TKLFMAPEVYCKKYTPMK
.|  | .|. ||||.  . ...                                                    ..   |  |  .||||.    |..  
LDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---YGKA-

SDIWS--LGVTLYFLATQTYPFNAP----------DIEKLKQCISIGL-FATDKVQN---------------KNLLAVISKCLDRDPEKRPT--------
 |.||  ||. .| . |   ||..           . ... | | .|  | ..||.                ...   |.|.| .|||||..        
CDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGD

--ADEILQMPYF
  |.|| . |.|
KGAEEIKNHPWF
Kinase 80474.m00072.AA CAMKL 8-198 30 1.1e-47 150.18 In-house 77-297 (297) Show / Hide 
Range on Protein: 8-198
Range on HMM: 77-297/297
Sequence Identity: 30% (67 aa)

IVRLYQIYRYNDF------IYMVMEYCPTD---LYKVFSAG----GKLYEEDIYRYAHDAVLAIKSVHDKNIAHCDIKPANFFIDTYG--RVKIGDFGLA
|..||...   ..      ||.|||||.     |.    .     |.. |..  ||    | |..  |...|.| |||| |  .|  |   .|| |||..
IIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFS

SF-----NGSSCSCKMAKGTKLFMAPEVYCK--K-YTPMKSDIWSLGVTLYFLATQTYPFNAP--------DIEKLKQCISIGLFATDKVQNK-NLLAVI
 .     .|.   .|.  |.  .||||.. .  | |   | ||||.||.||.. . ..||...        .| .|.  | .| .  ..      .   |
NMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLI

SKCLDRDPEKRPTADEILQMPYF
.| | ..||||||...|.. | .
RKMLQVNPEKRPTIHQIMNHPWM
Kinase 80474.m00072.AA Ciliate-E2 6-198 24 4.6e-41 138.7 In-house 92-365 (365) Show / Hide 
Range on Protein: 6-198
Range on HMM: 92-365/365
Sequence Identity: 24% (69 aa)

PRIVRLYQIYR--YNDFIYMVMEYCPT-DLYK------VFS------AGGKLYEEDIYRY-AHDAV--------------LAIKSVHDKN-IAHCDIKPA
| |...|  .    .. ||.|||||   ||..       ..      . ... |. | .. .. .               ||... | || | | |||| 
PNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE

NFFIDTYGRVKIGDFGLASFNGSS---------CSCKMAKG------------------------TKLFMAPEVYC---------KKYTPMKSDIWSLGV
| ..     .|| ||||. ..  .         |  .|  .                        |  .||||..          .|.   |.|||||||
NILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

TLYFLATQTYPFNAPDIEKLKQCISIGLFA--------------TDKVQNKNLLAVISK----CLDRDPEKRPT-ADEILQMPYF
.||.. .  .||    ... |||     ..                |   ..    |.|    .|..|||||.| ...||. |.|
ILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 80474.m00072.AA Ciliate-E2-Unclassified 3-198 24 4.4e-40 136.74 In-house 78-352 (352) Show / Hide 
Range on Protein: 3-198
Range on HMM: 78-352/352
Sequence Identity: 24% (67 aa)

IDDPRIVRLYQIYRYNDFIYMVMEYC------------------PTDLYKVFSAGGKLYEEDIY-----RYAHDAVLAIKSVHDKN-IAHCDIKPANFFI
...| ||... . .  . ||.|||||                    ||..    . .. |. .      .|.   ...... | || | | |||| | ..
HPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILF

DTYG---RVKIGDFGLASFNG----------------SSCSCKMAKGTKLFM----APEVYCK-KYTPM---KSDIWSLGVTLYFLATQTYPFNAPDIEK
|  |   ..|| |||......                ... ..   ||  .|    ||||... .|  .   |.||||||| ||.. ...|||.... |.
DNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQ

----------------LKQCISIG---LFATDK-----VQNKNLLAVIS----KCLDRDPEKRPTADEILQMPYF
                |.| |  .    .  ..       ...    |.    |.|. .|.||.|...||. |.|
HQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
S_TKc 80474.m00072.AA S_TKc 1-198 28 1e-39 139.18 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-198
Range on HMM: 19-231/231
Sequence Identity: 28% (69 aa)

MRID------------------------DPRIVRLYQIYRYNDFIYMVMEYCPT---DLYKVFSAGGK------LYEEDIYRYAHDAVLAIKSVHDKNIA
  ..                         | ||.|| ...  |..|||||||..   ||...    |.      . | .. .|..  ..|..  |...| 
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII

HCDIKPANFFIDTYGRVKIGDFGLASFNGSSCSCKMAKGTKLFMAPEVYCKKYTPMKSDIWSLGVTLYFLATQTYPFNAPDIEKLKQCISIGLFATDKVQ
|.|.||.| ..|.  ..||.||||| .       .   ||  .|||||   .|.. |.|.||.|..|| ...   ||   ..... . |           
HRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------

NKNLLAVISKCLDRDPEKRPTADEILQ-------MPYF
 . ..  |.|||..|||||||| |.||       .|.|
SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80474.m00072.AA ULK 8-198 24 5.8e-38 132.3 In-house 77-324 (324) Show / Hide 
Range on Protein: 8-198
Range on HMM: 77-324/324
Sequence Identity: 24% (60 aa)

IVRLYQIYRYNDF--IYMVMEYCPT-DLYKVFS---------AGGKLYEEDIYRYAHDAVLAIKSVHDKNIAHCDIKPANFFIDTY------------GR
||.|| ...  ..  ||..||||.  || .             ...| |. .  . .. . . |  |..|| |.||||.|  |               |.
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGV

VKIGDFGLASFNGSS----CSCKMAK------GTKLFMAPEVYCKK-----YTPMKSDIWSLGVTLYFLATQTYPFNAPDIEKLK---------------
.||.|||.| .  .     . |. ..      || |.|||..  ..     |.  |.||||||. .| . .  |||... .....               
LKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQI

QCISIGLFATD--KVQN--KNLLAVISKCLDRDPEKRPTADEILQMPYF
.     .   .  | ..  ...   |...| .|...| . .||...| |
YIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 80474.m00072.AA ULK 8-198 24 3.8e-37 127.25 In-house 80-329 (329) Show / Hide 
Range on Protein: 8-198
Range on HMM: 80-329/329
Sequence Identity: 24% (61 aa)

IVRLYQIYRYNDF--IYMVMEYCPT-DLYKVFS----------AGGKLYEEDIYRYAHDAVLAIKSVHDKNIAHCDIKPANFFIDTY------------G
||.|| ...  ..  ||..||||.  || .  .           ...| |. .  . .. . . |  |..|| |.||||.|  |.              |
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNG

RVKIGDFGLASFNGSS-------CSCK---MAKGTKLFMAPEVYCKK-----YTPMKSDIWSLGVTLYFLATQTYPFNAPDIEKLK-----QCISIG---
..||.|||.| .  ..       ..|.     .|| |.|||..  ..     |.  |.||||||. .| . .  .||.|. .....     . | ..   
VLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPW

--------LFAT----DKVQNKNLLAVISKCLDRDPEKRPTADEILQMPYF
        |       |..  ...   |...| .|...| . .|....| |
PQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 80474.m00072.AA STE 3-198 22 2.7e-35 122.1 In-house 88-359 (359) Show / Hide 
Range on Protein: 3-198
Range on HMM: 88-359/359
Sequence Identity: 22% (64 aa)

IDDPRIVRLYQIYRYN-------DFIYMVMEYCP----TDLYK-VFSAGGKLY----------EEDIYRYAHDAVLA-IKSVHDKNIAHCDIKPANFFID
.  | ||. |  | ..       | ....|||..    .|..| ... |. |           |. | ..... . .  .  |...| | |||||| .. 
M-HPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-

TYGRVKIGDFGLAS-FNGS----------------SCSCKMAKGTKLFMAPEVYCK------KYTPMKSDIWSLGVTLYFLATQTYPF---NAP------
    ||. |||... .. |                .  ..   ||  .|||||  .      |    |.|||||| |.  .||  .|.   . .      
----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMI

------------------DIEKLKQCIS-----------IGLFATDKVQNKNLLAVISKCLDRDPEKRPTADEILQ--MPYF
                  .. .|.. .|             .    .   ...   |.|||..||.|||||.. |.   | .
PFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGT-T--YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 80474.m00072.AA NEK 2-198 33 2.2e-31 107.97 In-house 60-286 (286) Show / Hide 
Range on Protein: 2-198
Range on HMM: 60-286/286
Sequence Identity: 33% (77 aa)

RIDDPRIVRLYQIYRYND--FIYMVMEYCPT--DLYKV---FSAG---GKLYEE-DIYRYAHDAVLAIKSVHDK-----NIAHCDIKPANFFIDTYGR--
... | ||. |  .  ..  ... |||||    |||.       .   ||. ||  | ..    .||.| .||.     .| | ||||.| |..  ..  
QLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDY

--VKIGDFGLASFNGSSCSCKMAK----GTKLFMAPEVY-CKKYTPMKSDIWSLGVTLYFLATQ--TYPFNAP--DIEKLKQCISIGLFATDKVQNK---
  |||||||..     . ...||.    ||  .|.|||   |.|.  ||||||||. || ..|.    ||.|   ... |   |  |    .... .   
HNVKIGDFGISKV--LNHTTDMAYTTQVGTPYYMSPEVCQNKPYN-NKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKG-PQYPPIPSHRMY

--NLLAVISKCLDRDPEKRPTADEILQMPYF
   |  .||..| .|||.||....||.||. 
SQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 80474.m00072.AA TKL 6-196 19 6e-29 101.38 In-house 85-364 (364) Show / Hide 
Range on Protein: 6-196
Range on HMM: 85-364/364
Sequence Identity: 19% (57 aa)

PRIVRLYQIYRYNDF-------------IYMVMEYC-PTDLYKVFSAGGKLYEEDIYRYAHDAVLAIKSVHD--------KNIAHCDIKPANFFIDTYGR
| ||... .  ....             ...|||||   .|. ..        . . | |.|. ...   |         ..|.|.|.|..| ..|  ..
PNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWT

--------------VKIGDFGLASFNGSSCSCKM--------------------AKGTKLFMAPEVYCKK--YTP--------------MKSDIWSLGVT
              .||.||||. |.  | . ..                      ||. .|||||  ..  ||                |.|..| |. 
NVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIV

LYFLATQTYPFN-APDIEKL---------KQCI--SIGLFATDKVQN-----------KNLLAVISKCLDRDPEKRPTADEILQMP
|. ..|   |.   | .. .         ....  .  .   .  ||           . .   . .| | ||||||...|||.  
LWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
TyrKc 80474.m00072.AA TyrKc 1-196 19 1.1e-07 -98.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-196
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

MR--------------------------------------------I--DDPRIVRLYQIYRYN-------DFIYMVMEYCPT-DLYKVFSAGGK-LYEE
 .                                            .  . | ||||| . .         . ...||||.|  || .   . .. |  .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

DIYRYAHDAVLAIKSVHDKNIAHCDIKPANFFIDTYGRVKIGDFGLASFNGSS------CSCKMAK---GTK--L---FMAPEVYCKK-YTPMKSDIWSL
|   .....       |.||. | |.   |  ..  ..|||.||||. . ..        . ...|   |.|  |    ||||.  .. .|. |||.|| 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KSDVWSF

GVTLYFLATQTYPFNAP------DIEKLKQCISIGLFATDKVQ---------NKNLLAVISKCLDRDPEKRPTADEILQMP
||... . |   .          . . . ...  |                  . .  ....| ..|||.|||  || .  
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF