82588.m00113

Species: T.vaginalis
Alias: 82588.m00113, TvagK0155
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
82588.m00113.AA Protein None 212 None Fasta, JSON
82588.m00113.kin_dom Protein Kinase Domain None 148 None Fasta, JSON

Protein domain

Protein domains of 82588.m00113.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82588.m00113.AA Pkinase 37-173 26 1.2e-31 113.04 Pfam 124-293 (293) Show / Hide
Range on Protein: 37-173
Range on HMM: 124-293/293
Sequence Identity: 26% (46 aa)

CHEFGIRHGDVKPSNFLIDKYGRV----KICDFGFSQK--LNRDENNTNFSGTFIYESPEIIRQEPFDGFAADIWALGVSYFILITGQCPWNLY------
||. || | |.||.|.|||. | .    ||||||.. .  . ... .| | ||  | .||.||  . .| ..|.|..|.  .....|. |.         
CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNH

SKDAMIKSIQNAIFDEFQIND---------------------LLLRRIVSLCLQIDPTKRPSAEDLVNM--L
....||. |  .....   ..                       .. ... ||. ||.|||.||....   .
DQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 82588.m00113.AA Ciliate-E2 34-171 21 6e-30 99.99 In-house 173-361 (365) Show / Hide
Range on Protein: 34-171
Range on HMM: 173-361/365
Sequence Identity: 21% (43 aa)

LQSCHEFG-IRHGDVKPSNFLIDKYGRVKICDFGFSQKLNRDENNTN--------------------------------FSGTFIYESPEIIRQEPFDG-
|...|. . | | | ||.| |.     .||.|||.|.|.. |..|.                                 . ||  | .|||.. .. |. 
LEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ

-------FAADIWALGVSYFILITGQCPWNLYSKDAMIKSIQNAIFD------------------EFQINDLLLRRIVSL----CLQIDPTKRPS-AEDL
       ...|||.|||  .....|. |.        .. |..  .|                  ...  ..    . .     .|| || ||.. .|..
QKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

VN
 |
LN

Kinase 82588.m00113.AA CAMK 37-171 19 7.7e-30 92.76 In-house 195-421 (425) Show / Hide
Range on Protein: 37-171
Range on HMM: 195-421/425
Sequence Identity: 19% (45 aa)

CHEFGIRHGDVKPSNFLIDKY-----------------GRVKICDFGFSQKLNRDENNTN------------------------FSGTFIYES-PEIIRQ
||. .| | | || | |.|.                  . .||.||||..|....|||..                        | ||  | . ||....
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

-------------EPFDGFAADIWALGVSYFILITGQCPWNLY-------------SKDAMIKSIQNAIFD-EFQINDL---------------------
             .| .|...|.|..||  .|. .|  |..               .   . . |... .| .    .                      
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

--LLRRIVSLCLQIDPTKRPSAEDLVN
    .  .. .|| ||.||...|.  |
SQECKDLIRKMLQVDPEKRMTIEQCLN

Kinase 82588.m00113.AA MARK 37-171 32 1.1e-29 94.35 In-house 120-258 (262) Show / Hide
Range on Protein: 37-171
Range on HMM: 120-258/262
Sequence Identity: 32% (46 aa)

CHEFGIRHGDVKPSNFLIDKYG--RVKICDFGFSQKLNRDENNTNFSGTFIYESPEIIRQEPFDGFAADIWALGVSYFILITGQCPWNLYS--KDAMIKS
||. .| | | || | |||. |   .||.||||| . . ..  . | ||  | .|||. ..| ||...|||.|||  .....|. |.  ..     . | 
CHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKK

IQNAIFDEFQINDL--LLRRIVSLCLQIDPTKRPSAEDLVN
|..  .| .  . .   .| .... |...| .||..|....
ILRGKYD-IPCH-VSKECRNLIQRLLTVNPEERPTIEEIMK

Kinase 82588.m00113.AA Ciliate-E2-Unclassified 1-171 19 2.2e-29 99.12 In-house 100-348 (352) Show / Hide
Range on Protein: 1-171
Range on HMM: 100-348/352
Sequence Identity: 19% (48 aa)

MEYCPSSIDKIFLE-RWV-----------------LTNEELY-----RYAIGMAQSLQSCHEFG-IRHGDVKPSNFLIDKYG---RVKICDFGFSQKLN-
||||.    . ... |.                  .| ..       .|.    | |...|. . | | | ||.| |.|. |   ..||.|||.| |.. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------RDENNTNFSGTFIYE----SPEIIRQEPFDG---FAADIWALGVSYFILITGQCPWNLYSKDA----------------MIKSIQ
               .... . |.|| .|     .||.....  |.   ...|||.|||  . ...|..| . ....                 ... |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NAIFDEF--------QINDLLLRRIVS----LCLQIDPTKRPSAEDLVN
. ... .        .. .     ...     .|. .| ||...|.. |
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN

Kinase 82588.m00113.AA AGC 34-169 18 1.1e-28 69.99 In-house 166-389 (395) Show / Hide
Range on Protein: 34-169
Range on HMM: 166-389/395
Sequence Identity: 18% (43 aa)

LQSCHE-FGIRHGD-VKPSNFLIDKYGRVKICDFGFSQKLNRDE---------------------------------------------------NNTNF
|.. |.  || | | .|| | |.|. | .|..|||.. ....|.                                                    .. |
LEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF

SG--TFIYESPEIIRQEPFDGFAADIWA--LGVSYFILITGQCPWNL----------YSKDAMIKSIQNAI---FDEFQIN-------------DLLLRR
 |  |  | .|||.      |.|.|.|.  ||.  . ..||. | .           .... | ..|.| .   ... ...             .  .. 
CGPCTPEYMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKD

IVSLCLQIDPTKRPS----------AEDL
... .|. ||.||.           ||..
LIKKLLCKDPEKRLGCGGNDFGDKGAEEI

Kinase 82588.m00113.AA CAMKL 37-171 27 3e-28 87.12 In-house 143-293 (297) Show / Hide
Range on Protein: 37-171
Range on HMM: 143-293/297
Sequence Identity: 27% (43 aa)

CHEFGIRHGDVKPSNFLIDKYG--RVKICDFGFSQKLNR-----DENNTNFSGTFIYESPEIIRQ--EPFDGFAADIWALGVSYFILITGQCPWN-----
||. || | | || | |.|. |   .||.||||| .  .     ..  . | |.  | .|||.    .|.||...|||..||  . ...|. |..     
CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN

-----LYSKDAMIKSIQNAIFDEFQINDLLLRRIVSLCLQIDPTKRPSAEDLVN
      . .   .. ..   .. .   .  .|.. .  || .|.|||......|
KQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

Kinase 82588.m00113.AA STE 1-169 21 1.4e-26 90.95 In-house 116-351 (359) Show / Hide
Range on Protein: 1-169
Range on HMM: 116-351/359
Sequence Identity: 21% (52 aa)

MEYCP-SSIDKIFLER--------------WVLTNEELYRYAIGMAQS-LQSCHEFGIRHGDVKPSNFLIDKYGRVKICDFGFSQKLNR-----------
|||..  |.|.|  ..              ...  ... ...    .  |.  |. .| | |.||.| |.     ||.||||.. .|.            
MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNII

------DENNTNFSGTFIYESPEIIRQEPFD-----GFAADIWALGVSYFILITGQCPW-NLYSKDAMIKSIQN-AIF-----------DEFQIND----
      ..... | ||  . .||.|.|.  .     .. .||| ||     ..||. || ...   ||   ..| ...           .  .. |    
DCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQ

------------------LLLRRIVSLCLQIDPTKRPSAEDL
                    ..  ...|||.|| |||.|..|
NEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQL

Kinase 82588.m00113.AA CAMKK 29-120 27 5.7e-24 72.59 In-house 184-325 (396) Show / Hide
Range on Protein: 29-120
Range on HMM: 184-325/396
Sequence Identity: 27% (39 aa)

GMAQSLQSCH-EFG-------------------IRHGDVKPSNFLIDKYG---RVKICDFGFSQKL-NRDENNTN-----------FSGTFIYESPEIIR
.... |. .| . .                   | | | ||.| |||. |   .|||.||| |...   |... |             ||  .  || ..
DCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCS

QEP---------------FDGFAADIWALGVSYFILITGQCP
 |                ..|.|||||||||. .....|.||
KENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCP

Kinase 82588.m00113.AA TKL 1-173 17 1.7e-22 77.84 In-house 117-364 (364) Show / Hide
Range on Protein: 1-173
Range on HMM: 117-364/364
Sequence Identity: 17% (45 aa)

MEYCPSSI-DKIFLERWVLTNEELYRYAIGMAQSLQSCHEFG--------IRHGDVKPSNFLIDKYGR--------------VKICDFGFSQKLNRDEN-
|||||      ...       . . | |...|. ..  |  .        | | | |..| |.|. ..              .||||||.|. .....| 
MEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNM

-------------------NTNFSGTFIYESPEIIRQEPFDGFAA---------------DIWALGVSYFILITGQCPW--NLYS------------KDA
                   . .  ||. . .||..|.....  ..               |... |.  . ..|.. |.  . |.            . .
NDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMV

MIKSIQNAIFDEFQ------INDLL---LRRIVSLCLQIDPTKRPSAEDLVNML
  |. .  | .. |       ..     ....   | . ||.||||.....  |
CDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 82588.m00113.AA ULK 38-163 23 1.6e-20 69.56 In-house 143-312 (324) Show / Hide
Range on Protein: 38-163
Range on HMM: 143-312/324
Sequence Identity: 23% (40 aa)

HEFGIRHGDVKPSNFLIDKY------------GRVKICDFGFSQKLNRDENNTNFS----------GTFIYESPEIIR----QEPFDGFAADIWALGVSY
|. .| | | ||.| || .             |..||.||||..... .. . .            || .| .|.|.     |.|.. . .||| ||. .
HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF

FILITGQCP---WNLYSKDA-MIKSIQN------AIFD---EFQIND------LLLRRIVSLCLQIDPTKR
. ...|..|   |  .. .  ..| |.|       | .   .|....        .. . . .||.|...|
YEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR

Kinase 82588.m00113.AA S_TKc 1-173 18 2.2e-13 19.26 SMART 1-231 (231) Show / Hide
Range on Protein: 1-173
Range on HMM: 1-231/231
Sequence Identity: 18% (48 aa)

M-----------------------------------------------------------------EYCPS---SIDKIFLERWV------LTNEELYRY
                                                                  |||.    .  ..  .|        ..  .  .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

AIGMAQSLQSCHEFGIRHGDVKPSNFLIDKYGRVKICDFGFSQKLNRDENNTNFSGTFIYESPEIIRQEPFDGFAADIWALGVSYFILITGQCPWNLYSK
.  ... |. ||. || | |.||.| |.|.  ..||||||.. .|      | | ||  | .||..   .......|.|..|.  .....|. |.     
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QM

DAMIKSIQNAIFDEFQINDLLLRRIVSLCLQIDPTKRPSAEDLVN---------ML
..|.| |           .  .. ... ||| ||.|||.| .. .          .
QMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF