Gene 80222.m00140 (T.vaginalis)

80222.m00140

Species: T.vaginalis
Alias: 80222.m00140, TvagK0936
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: PKR-like

Sequence

Name Sequence Type Origin Length Description Download
80222.m00140.AA Protein None 347 None Fasta, JSON
80222.m00140.kin_dom Protein Kinase Domain None 247 None Fasta, JSON

Protein domain

Protein domains of 80222.m00140.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80222.m00140.AA Ciliate-B2 211-279 28 2.4e-18 39.68 In-house 120-197 (197) Show / Hide 
Range on Protein: 211-279
Range on HMM: 120-197/197
Sequence Identity: 28% (22 aa)

IHHKNIVHCNIKPSNILMSIDGIPKLCDFGRAYLITNPSKISQIQEKDSFAAPEFPENI---------ATSCDVYSFA
.. .||.|  |||.|||..  |  ..||||.  .. . ..|.  ..  ..| ||  |..             |.||  
FRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 80222.m00140.AA Ciliate-E2-Unclassified 168-278 19 2e-15 50.01 In-house 91-256 (352) Show / Hide 
Range on Protein: 168-278
Range on HMM: 91-256/352
Sequence Identity: 19% (32 aa)

KIEFLFYIQTELCSRDNILKACKD--------------------QDMTNIL-----DLLADAASGISYIHHKN-IVHCNIKPSNILMSIDG---IPKLCD
. .. .|| .|.|   . .. .|.                     .  ...     ...|   .|..|.|||| |.| .|||.|||.. .|    .|..|
QDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIID

FGRAYLITNPSKI------------SQIQEKDS----FA----APEFPENIATS------CDVYSF
|| .. . .....            .|..   .    .     |||  ..   .      ||..|.
FGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSL
Kinase 80222.m00140.AA Ciliate-E3 170-242 37 2.6e-14 41.3 In-house 77-153 (202) Show / Hide 
Range on Protein: 170-242
Range on HMM: 77-153/202
Sequence Identity: 37% (29 aa)

EFLFYIQTELCSRDNILKACKDQDMTN--ILDLLADAASGISYIHHKNIVHCNIKPSNILMSIDG---IPKLCDFGRA
. .| .| |.||. .     |.|  |   |.|. . .  |.  || ||| |  |||.||| .      | | |||| .
KMIFIVQ-EYCSNGDLYHYIKQQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGES
Kinase 80222.m00140.AA TKL 177-281 16 1e-13 45.76 In-house 117-278 (364) Show / Hide 
Range on Protein: 177-281
Range on HMM: 117-278/364
Sequence Identity: 16% (28 aa)

TELCSRDNILKACKDQDMTNILDLLADAASGISYIHH--------KNIVHCNIKPSNILMSIDGI--------------PKLCDFGRAYLITNPSKISQI
.|.|.. . |       .  ....  |.|.|..| |         ..|.|...|..|||   ..               .|.|||| .  ... .. . .
MEYCPGGSLLHYLH---WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDT

Q--------------EKDSFA------APEF------PENIA------------TSCDVYSFALI
.               . .        |||        .. .            ..||||||...
MTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIV
Kinase 80222.m00140.AA CAMKL 206-240 45 1.7e-13 39.29 In-house 138-174 (297) Show / Hide 
Range on Protein: 206-240
Range on HMM: 138-174/297
Sequence Identity: 45% (17 aa)

SGISYIHHKNIVHCNIKPSNILMSIDG--IPKLCDFG
|...|.| ..|||  ||| ||| . .|    |..|||
SAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFG
Kinase 80222.m00140.AA S_TKc 85-336 17 2.4e-13 18.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 85-336
Range on HMM: 1-231/231
Sequence Identity: 17% (50 aa)

FESKNT-------VVLAAVNHIDRLIYCIKRTSFEMDTVDPQDVMREASILQELVHPNIAKYNNSWIEFAVDGKVSEYLDPQDSKPLQNMKIEFLFYIQT
.|  ..       .|  .... .  |. ||. .        ....|| .||..  |||| |.  .. .                           .|. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-------------------------DHLYMVM

ELCSR-----DNILKACKD------QDMTNILDLLADAASGISYIHHKNIVHCNIKPSNILMSIDGIPKLCDFGRAYLITNPSKISQIQEKDSF------
|.|.        ..| ..        .   .  ...  .... |.| ..|.|. .||.|||..     |.|||| | ..            ..|      
EYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWY

AAPEFPENIAT-SCDVYSFALISVLALT-----GSDETKLAEIKENFPQMEDVPEQVVSIIKECLDENPENRPQIDSVID---------VF
 |||      . .||..|.  |    |.       .. .. ..          .... ..|. ||. .||.|| .  .            |
MAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80222.m00140.AA MARK 206-240 51 2.9e-13 39.9 In-house 115-151 (262) Show / Hide 
Range on Protein: 206-240
Range on HMM: 115-151/262
Sequence Identity: 51% (19 aa)

SGISYIHHKNIVHCNIKPSNILMSIDG--IPKLCDFG
|...| | |||||. ||| |||.  .|    |..|||
SAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFG
Kinase 80222.m00140.AA WEE 174-259 25 3.4e-13 40.7 In-house 81-197 (297) Show / Hide 
Range on Protein: 174-259
Range on HMM: 81-197/297
Sequence Identity: 25% (30 aa)

YIQTELCSRDN-----ILKACKDQDM----TNILDLLADAASGISYIHHK-NIVHCNIKPSNILMSIDG--------------------IPKLCDFGRAY
|||.|.| . .     ... |.  .      .| ..| | . |...|| . ..||  |||.||..| ..                    . |. ||| . 
YIQMEYCNGGSNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVT

LIT-NPSKISQIQEKDS
 .. |...  |.|| ||
DMNSNNNNPHQEQEGDS
Kinase 80222.m00140.AA Ciliate-E2 173-278 15 4.4e-13 41.25 In-house 109-282 (365) Show / Hide 
Range on Protein: 173-278
Range on HMM: 109-282/365
Sequence Identity: 15% (27 aa)

FYIQTELCSRDNILKACKDQ--------------DMTNILDLLADAAS---------------GISYIHHKN-IVHCNIKPSNILMSIDGIPKLCDFGRA
.|. .|.|.  . .. .|..              ..  |... .  ..               .. |.| || |.| .|||.|||.     .|..||| .
IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLS

YLITNPSK------ISQIQEKDS---------------------------FAAPEFPENIA-----------TSCDVYSF
  ......      ....    .                           . |||  ..             ..||..|.
KKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL
Kinase 80222.m00140.AA CDK 206-250 30 3e-12 35.32 In-house 119-174 (284) Show / Hide 
Range on Protein: 206-250
Range on HMM: 119-174/284
Sequence Identity: 30% (17 aa)

SGISYIHHKNIVHCNIKPSNILMSIDGI-----PKLCDFGRAYLITN------PSK
.|..|.|...|.|  .||.|||.. .|.      |. ||| | .  .      |..
RGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNR
Kinase 80222.m00140.AA Ciliate-A1 173-240 32 3.7e-12 37.63 In-house 76-146 (301) Show / Hide 
Range on Protein: 173-240
Range on HMM: 76-146/301
Sequence Identity: 32% (23 aa)

FYIQTELCSRDNILKACKDQD---MTNILDLLADAASGISYIHHKNIVHCNIKPSNILMSIDGIPKLCDFG
..| .| |   |    |.  |      | ....   .|.. || .||.|  .|| |||.  |   |.||.|
MFIIMEYCQYGNLFNYCYQNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLG
Kinase 80222.m00140.AA Pkinase 205-240 40 3.5e-09 33.57 Pfam 118-157 (293) Show / Hide 
Range on Protein: 205-240
Range on HMM: 118-157/293
Sequence Identity: 40% (16 aa)

ASGISYIHHKNIVHCNIKPSNILMSIDGIP----KLCDFG
..|. |.| ..|.|. .||.|||.. .| .    |.||||
LRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFG
Kinase 80222.m00140.AA TyrKc 84-336 18 2.5e-08 -87.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 84-336
Range on HMM: 1-280/280
Sequence Identity: 18% (60 aa)

IFESKN-------TVVLAAVNHIDRLIYCIKRTSFEMDTVDPQDVMREASILQEL--VHPNIAKY--------------NNSWI--EFAVDGKVSEYL-D
|   |        .|...  . |.  . ..|  .        .| ||||.|. .|   |||| .                  .|  |..  |   .|| .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PQDSKPLQNMKIEFLFYIQTELCSRDNILKACKDQDMTNILDLLADAASGISYIHHKNIVHCNIKPSNILMSIDGIPKLCDFGRAYLITNP-SKISQIQE
...                                 |   |.   ..|.| .|.|.||..|  .   |.| . ... | .||| .  |..  ..     .
HRPK------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---ES

KDSFAA-----PEF--------PENIATS-----CDVYSF--------ALISVLALT-----GSDETKLAEIKEN--FPQMED--------VPEQVVSII
||   .       .        || | ..      ||.||         .             |..  .. .|.    ||...         |. . .|.
KDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIM

KECLDENPENRPQIDSVIDVF
|.| .|.||.||    ... |
KQCWHEDPEDRPTFSEIHECF
Kinase 80222.m00140.AA TKL 298-336 23 6.6e-07 20.92 In-house 328-364 (364) Show / Hide 
Range on Protein: 298-336
Range on HMM: 328-364/364
Sequence Identity: 23% (9 aa)

KENFPQMEDVPEQVVSIIKECLDENPENRPQIDSVIDVF
|   .. .|.|... .....| |..||.||  . ... .
K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 80222.m00140.AA WEE 78-145 27 1.3e-05 14.91 In-house 1-76 (297) Show / Hide 
Range on Protein: 78-145
Range on HMM: 1-76/297
Sequence Identity: 27% (21 aa)

FTVVVKIFESKNTVVLAAVNHIDRLIYCIKRT-SFEMDTVDPQDVMREASILQELV-------HPNIAKYNNSWIE
|..| || |     | .... ||  || ||.. .   .. . ..  ||. .. .|        ||.| .| ..|.|
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEE
Kinase 80222.m00140.AA MARK 119-139 52 0.000188 10.66 In-house 44-64 (262) Show / Hide 
Range on Protein: 119-139
Range on HMM: 44-64/262
Sequence Identity: 52% (11 aa)

QDVMREASILQELVHPNIAKY
. ||||..|.. | |||| |.
KNVMREIEIMKKLDHPNIIKL
Kinase 80222.m00140.AA CDK 123-136 71 0.000406 8.89 In-house 57-69 (284) Show / Hide 
Range on Protein: 123-136
Range on HMM: 57-69/284
Sequence Identity: 71% (10 aa)

REASILQELVHPNI
|| |.|.|| ||||
REISLLKEL-HPNI
Kinase 80222.m00140.AA Ciliate-A1 298-339 25 0.000605 9.24 In-house 259-301 (301) Show / Hide 
Range on Protein: 298-339
Range on HMM: 259-301/301
Sequence Identity: 25% (11 aa)

KENFPQME-DVPEQVVSIIKECLDENPENRPQIDSVIDVFESA
| .||.|     |... .|.  .  .|.|| . . .||     
KIIFPPMQEPRFEELQNLIFKMMQYEPNNRCSLQQCIDCLYIF
Kinase 80222.m00140.AA CAMKL 117-138 40 0.008981 4.51 In-house 56-79 (297) Show / Hide 
Range on Protein: 117-138
Range on HMM: 56-79/297
Sequence Identity: 40% (10 aa)

DPQDVMREASILQELV---HPNIAK
|.  . ||..|.. |    |||| |
DM-RIRREIQIMKMLNIGKHPNIIK
Kinase 80222.m00140.AA Ciliate-E2 300-334 14 0.016042 4.45 In-house 306-361 (365) Show / Hide 
Range on Protein: 300-334
Range on HMM: 306-361/365
Sequence Identity: 14% (8 aa)

NFPQM----------------EDVPEQVVSIIKE----CLDENPENRPQ-IDSVID
.||.                 .......  .||     .|. .||.|.. .. ...
DFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 80222.m00140.AA Pkinase 91-136 22 2.90973 2.01 Pfam 14-62 (293) Show / Hide 
Range on Protein: 91-136
Range on HMM: 14-62/293
Sequence Identity: 22% (11 aa)

VVLAAVNHIDRLIYCIKRTSFEMDTVDPQDVM----REASILQELVHPNI
.|  .... .. |...|. . . .. . .|.     .|..|...| ||||
CVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNI
Kinase 80222.m00140.AA Pkinase 290-327 16 4.217317 1.44 Pfam 228-282 (293) Show / Hide 
Range on Protein: 290-327
Range on HMM: 228-282/293
Sequence Identity: 16% (9 aa)

DETKLAEIKENFPQMEDVP-----------------EQVVSIIKECLDENPENRP
.... .......|.  ...                 |   ..|| ||. .|. ||
CRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP