Gene 97114.m00197 (T.vaginalis)

97114.m00197

Species: T.vaginalis
Alias: TvagK0969, 97114.m00197
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
97114.m00197.AA Protein None 306 None Fasta, JSON
97114.m00197.kin_dom Protein Kinase Domain None 220 None Fasta, JSON

Protein domain

Protein domains of 97114.m00197.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97114.m00197.AA Ciliate-E2 17-254 20 1.9e-40 136.56 In-house 1-353 (365) Show / Hide 
Range on Protein: 17-254
Range on HMM: 1-353/365
Sequence Identity: 20% (73 aa)

YQVVRLIASSSVA-----KHFEVSN-------------------AKGFTFDVKVYNHA---AASNIIDYYN---------NEKDILGTLIHPNIVETFDF
| ....| . . .     |. .| .                   .|.. . .|....    . ...|. ..         ||| || .| ||||.. ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TQNYSYLVFELCRDLSLESIVSSTRKCS-----------EKNVYVYLSQLIQ---------------GIEYLHSNN-IVHNNLNPSTIHFDRFGRI
||  ..|. |||.|.|   .|...  . .|..           || .  .  |..|               ..|||||.| |.| .. |. | |     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIVDFDYASISYKQNS-----------------DRCPH----------------SRYSFSPETYSGKPYDP--------RASDVWSFGAISYYLLSGQYP
||.|| .. .  ..|                  .|.|                 . .  .|| ..||.||          ..|.||.| | |..|.|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WSNNSEISYSDSLESSMKN-------------LYGKYDEKLIQLILD----CLSEDPSKRP
.    ..     .. . ..              . | ... ..||      .|  ||.||.
F---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI
Kinase 97114.m00197.AA Ciliate-E2-Unclassified 63-254 22 1.3e-29 99.91 In-house 72-341 (352) Show / Hide 
Range on Protein: 63-254
Range on HMM: 72-341/352
Sequence Identity: 22% (60 aa)

KDILGTLIHPNIVETFDFFQTQNYSYLVFELCRDLSLESIVSSTRK-----------------CSEKNVY-----VYLSQLIQGIEYLHSNN-IVHNNLN
..||  . ||.||  |. ||.... |.| |.|....|. . ..  |                  .|...       |. |..||.||||..| |.| .. 
QQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIK

PSTIHFDRFG---RIKIVDFDYASISYKQ------------------NSDRCPHSRYS---FSPETYSGKPYDPR---ASDVWSFGAISYYLLSGQYPWS
|. | ||  |   .||| ||  .. . ..                   ...|   .|     .|| . |. || .   ..|.||.| | |..| |.|| .
PENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFY

NNSEIS----------------YSDSLESSMKNLYG--------KYDEKLIQLIL----DCLSEDPSKRP
 |....                . .       .           . ... . .|      .|  .|.||.
DNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI
Kinase 97114.m00197.AA GIN4 65-214 32 1.5e-24 74.99 In-house 87-238 (293) Show / Hide 
Range on Protein: 65-214
Range on HMM: 87-238/293
Sequence Identity: 32% (50 aa)

ILGTLIHPNIVETFDFFQTQNYSYLVFELCRDLSLESIVSSTRKCSEKNVYVYLSQLIQGIEYLHSNNIVHNNLNPSTIHFDRFGR-IKIVDFDYASISY
|.  . |||... .| . |.|  ||| |      |  .. .  .  |.    |  |.| |. | |. ||.|  | |  .  |.. . ||| ||  | .  
IMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALET

KQN--SDRCPHSRYSFSPETYSGKPYDPRASDVWSFGAISYYLLSGQYPWSNN
...     |    |  .||  .| ||.  |||||| | | . || |. |. ..
DNKLLETSCGSPHYA-APEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEE
Kinase 97114.m00197.AA S_TKc 17-264 24 1.6e-24 88.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-264
Range on HMM: 1-231/231
Sequence Identity: 24% (64 aa)

YQVVRLIASSSVAKHFEVSNAK-GFTFDVKVYNHAAASNIIDYYNNEKDILGTLIHPNIVETFDFFQTQNYSYLVFELCRD--LSLESIVSSTRK-----
|...|.| . . .| . . . | |  . .|. .        .   .| .||    |||||  .|.||. .. |.|.|.|     .| ..  . ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-CSEKNVYVYLSQLIQGIEYLHSNNIVHNNLNPSTIHFDRFGRIKIVDFDYASISYKQNSDRCPHSRYSFSPETYSGKPYDPRASDVWSFGAISYYLLSG
  .|  .  |. |.....||.||..|.|  | |. | .|.  .||| ||  | .      . .  ...  .||     .|.....|.||.| | | .|.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

QYPWSNNSEISYSDSLESSMKNLYGKYDEKLIQLILDCLSEDPSKRPLASVAN-------SFFM
. |..          ..  .|..    .. ....|  ||  ||.||| | . .         ..
YPPFP---------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 97114.m00197.AA Ciliate-E2b 61-211 27 1.2e-23 68.92 In-house 49-210 (272) Show / Hide 
Range on Protein: 61-211
Range on HMM: 49-210/272
Sequence Identity: 27% (46 aa)

NEKDILGTLIHPNIVETFDFFQTQNYSYLVFELCRDLSLESIVSSTR--KCSEKNVYVYLSQLIQGIEYLHSNNIVHNNLNPSTIHFDRFGRIKIVDFDY
.|| .| .. ||.|.  .. |.. .. |.. |.|. ..|.....       |.. .  |  ... ..||||..||..  . |. |  |  | .|..|.  
QEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGT

ASISYKQNS--DRC------PHSRYSFSPETYS-----GKPYDPRASDVWSFGAISYYLLSGQYPW
| . ||.|.   |.      ||  |   ||  .     ||.|   ..|.||.| . | ...|. ||
AKHMYKKNEQMTRTFTIIGTPH--Y-MAPEIIQSLQPGGKGYT-YKVDIWSVGICLYEFMCGYVPW
Kinase 97114.m00197.AA PLK1 17-263 25 8.9e-20 61.45 In-house 1-253 (253) Show / Hide 
Range on Protein: 17-263
Range on HMM: 1-253/253
Sequence Identity: 25% (66 aa)

YQVVRLIASSSVAKHFEVSNAKGF-TFDVKVYNHA--AASNIIDYYNNEKDILGTLIHPNIVETFDFFQTQNYSYLVFELCRDLSLESIVSSTRKCSEKN
|.  | .     |. .|.....    | .||   .    ..  |    | .|   | |..||. ..||  ... |.| ||||  ||  .    .   |  
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

VYVYLSQLIQGIEYLHSNNIVHNNLNPSTIHFDRFGRIKIVDFDYASISYKQ---NSDRCPHSRYSFSPETYSGKPYDPRASDVWSFGAISYYLLSGQYP
   |. |...|..||| |.|.|  |    . ..   ..|| ||  |    ..      .|    |   ||  . |       |.|| | | | || || |
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNY-IAPEVLNKKGHSFEV-DIWSIGCIMYILLFGQPP

WSNNSEISYSDSLESSMKNLYGKYDEKLIQLILDCLSEDPSKRPLAS--VANSFF
.  ..       .      .  .  .   |||   | .||..|| ..  .   ||
FETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 97114.m00197.AA ULK 55-156 25 4.5e-17 56.2 In-house 53-186 (329) Show / Hide 
Range on Protein: 55-156
Range on HMM: 53-186/329
Sequence Identity: 25% (34 aa)

IIDYYNNEKDILGTLI--------HPNIVETFDFFQTQ--NYSYLVFELCRDLSLESIVSSTRKCSEKN----------VYVYLSQLIQGIEYLHSNNIV
...  .|| .|. .|         |||||. .|.|.|.  |. |...|.| .  ||.. .  .|..|.           .  .. |...|  .||..||.
MWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNII

HNNLNPSTIHFDRF------------GRIKIVDF
|  . |. |  .              |..|| ||
HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF
Kinase 97114.m00197.AA ULK 55-156 26 3.5e-16 53.97 In-house 53-182 (324) Show / Hide 
Range on Protein: 55-156
Range on HMM: 53-182/324
Sequence Identity: 26% (35 aa)

IIDYYNNEKDILGTLI---HPN--IVETFDFFQTQ--NYSYLVFELCRDLSLESIVSSTRK---------CSEKNVYVYLSQLIQGIEYLHSNNIVHNNL
...  .||  |. .|    |||  ||. .|.|.|.  |. |...|.| .  ||..    .|          ||. .  .. |...|  .||..||.|  .
MWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDI

NPSTIHFDRF------------GRIKIVDF
 |. |                 |..|| ||
KPQNILIHNGQPKTDSKKVHPNGVLKIADF
Kinase 97114.m00197.AA CAMK 61-156 20 3.9e-16 47.81 In-house 80-240 (425) Show / Hide 
Range on Protein: 61-156
Range on HMM: 80-240/425
Sequence Identity: 20% (34 aa)

NEKDILGT-------LIHPNIVETFDFFQ------------TQNY--------SYLVF---ELCRDLSL--E-------S-----------IVSSTRKCS
.| .|. .       | ||||.  .....            | ..         |.|.   |.|    |  .                   || .... .
REIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFT

EKNVYVYLSQLIQGIEYLHSNNIVHNNLNPSTIHFD-RF----------------GRIKIVDF
|. .  |  |......|.||.||||  | |  | .| ..                . |||.||
EREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 97114.m00197.AA CAMK-Unique 44-135 16 1e-15 48.17 In-house 29-180 (363) Show / Hide 
Range on Protein: 44-135
Range on HMM: 29-180/363
Sequence Identity: 16% (25 aa)

VKVYNHAAASNIIDYY-------------------NNEKDILGTLIHPNIVETFDF----FQTQN---------------YSYLVFELCRDLSLESIVSS
.|. . ....|.. .                     .| .|. .. ||||.. .|.    |.. .               | |.| |.| .  | ... .
CKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQK

--------------------TRKCSE--KNVYVYLSQLIQGIEYLHSNNIVH
                     .. ||    .  .  .| . ..|.||..|||
WDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVH
Kinase 97114.m00197.AA CAMK 178-254 23 6e-14 40.62 In-house 287-414 (425) Show / Hide 
Range on Protein: 178-254
Range on HMM: 287-414/425
Sequence Identity: 23% (31 aa)

S-PETYSG-------------KPYDPRASDVWSFGAISYYLLSGQYPWS--NNSEISYSDSLESSM----------KNLYGKYD-E--------------
. ||  .|             |||.....|.|| | | | .|.| .|.   ...||   |  |             | . |||| .              
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D--E--WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE

---------------KLIQLILDCLSEDPSKRP
                 ..||  .|  ||.||.
WWDDISDEFHHFVSQECKDLIRKMLQVDPEKRM
Kinase 97114.m00197.AA Pkinase 65-135 32 6.2e-14 50.34 Pfam 53-131 (293) Show / Hide 
Range on Protein: 65-135
Range on HMM: 53-131/293
Sequence Identity: 32% (26 aa)

ILGTLIHPNIVETFDFFQTQNYSYLVFELCRDL----SLESIVS--STRKC--SEKNVYVYLSQLIQGIEYLHSNNIVH
|.  | |||||...|.|.. .. |.|.|.|.      .| ...|  . ..   ||. .  |. |...|.||.||..|.|
IMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH
Kinase 97114.m00197.AA CAMKL 71-135 25 1.2e-13 39.75 In-house 74-150 (297) Show / Hide 
Range on Protein: 71-135
Range on HMM: 74-150/297
Sequence Identity: 25% (20 aa)

HPNIVETFDFFQTQNY------SYLVFELCRDLS--LESIVSST----RKCSEKNVYVYLSQLIQGIEYLHSNNIVH
||||.  .. ..|...       ||| |.|   .  |   . .     .. .|.    |  |.. ...|.||..|||
HPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVH
Kinase 97114.m00197.AA Pkinase 178-263 21 1.2e-12 45.85 Pfam 179-293 (293) Show / Hide 
Range on Protein: 178-263
Range on HMM: 179-293/293
Sequence Identity: 21% (25 aa)

SPETYSGKPYDPRASDVWSFGAISYYLLSGQYPWSNN-SEISYSDSLESSMKNLYGKYD---------------------------EKLIQLILDCLSED
.||   | .|.....|.||.| | |..|.|. |...   ...  | ..   ........                           | ....| .||  |
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

PSKRPLASVANSF--F
|.||| |  .     |
PKKRPTAEQILQHPWF
Kinase 97114.m00197.AA CAMKL 178-254 26 2.8e-10 28.84 In-house 201-286 (297) Show / Hide 
Range on Protein: 178-254
Range on HMM: 201-286/297
Sequence Identity: 26% (24 aa)

SPETYSG--KPYDPRASDVWSFGAISYYLLSGQYPWS-------NNSEISYSDSLESSMKNLYGKY---DEKLIQLILDCLSEDPSKRP
.|| ..|  |||| .. |.|| | | | .. |..|.        ... | |    . .    . ..   .  ...||   |  .|.|||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRP
Kinase 97114.m00197.AA TyrKc 40-263 18 3.4e-07 -106.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-263
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

FTFD---------------------VKVYNHAAASNIIDYYNNEKDILGTL--IHPNIVETFDFFQTQ-------NYSYLVFELCRDLSLESIVSSTRK-
 |..                     ||. .. |   . | . .|  |.  |   |||||  .    .|          ..|.|..   .| .   ..|. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA---REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

CSEKNVYVYLSQLIQGIEYLHSNNIVH-----------NNLNPSTIHFDRFGRIKIVDF----DYASI--------SYKQN---SDR--CP---------
 . |    .  |  .| |||||.|..|           .|.           ..|| ||    |  .          |..    . .   |         
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

-HSRYSFSPETYSGKPYDPRASDVWSFGAISYYLLS-GQYPWSN-----NSEISYSDSLESSMKNLYGKY---------DEKLIQLILDCLSEDPSKRPL
 ......             .|||||||   . ... || |...      | .     ... .     ..          ... |....|  |||..|| 
NYGKFTT-------------KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPT

ASVANSFF
 |   ..|
FSEIHECF
Kinase 97114.m00197.AA ULK 178-253 20 3e-06 17.95 In-house 219-317 (329) Show / Hide 
Range on Protein: 178-253
Range on HMM: 219-317/329
Sequence Identity: 20% (20 aa)

SPETYS----GKPYDPRASDVWSFGAISYYLLSGQYP---WSNNSEI-----SYSDS-------LESSMKNLY-----GKYDEKLIQLILDCLSEDPSKR
.|.  .    .|||.   .|.||.| | |..| |..|   | .|...     .  .         ..   . .      .  .....||  .|  |...|
APQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDR
Kinase 97114.m00197.AA ULK 178-253 22 8e-06 16.67 In-house 215-312 (324) Show / Hide 
Range on Protein: 178-253
Range on HMM: 215-312/324
Sequence Identity: 22% (22 aa)

SPETYS----GKPYDPRASDVWSFGAISYYLLSGQYP---WSNNSEI-------------SYSDSLESSMKNLYG---KYDEKLIQLILDCLSEDPSKR
.|.  .    .|||.   .|.||.| | |..| |.||   | .|...              .    .   .....   |  .....||  .|  |...|
APQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR
Kinase 97114.m00197.AA CAMK-Unique 178-210 30 2.4e-05 13.38 In-house 243-292 (363) Show / Hide 
Range on Protein: 178-210
Range on HMM: 243-292/363
Sequence Identity: 30% (15 aa)

SP--------------ETYSGKPYDPRAS---DVWSFGAISYYLLSGQYP
.|              |.  . .||   |   | || |.| ||.|.|  |
APEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPP