Gene 88200.m00264 (T.vaginalis)
88200.m00264
Species: T.vaginalis
Alias: 88200.m00264, TvagK0627
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 88200.m00264.AA | Protein | None | 2286 | None | Fasta, JSON |
| 88200.m00264.kin_dom | Protein Kinase Domain | None | 261 | None | Fasta, JSON |
Protein domains of 88200.m00264.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| HEAT | 88200.m00264.AA | HEAT | 418-443 | 23 | 0.000861 | 16.99 | Pfam | 1-26 (31) | Show / Hide |
Range on Protein: 418-443 Range on HMM: 1-26/31 Sequence Identity: 23% (6 aa) LIDQILNLLHSDNETIRVAAAKAIKQ ... .|..|..... .| ||.....| ILPHLLKCLNDPDWEVREAACWCLGQ |
|||||||||
| HEAT | 88200.m00264.AA | HEAT | 453-480 | 32 | 7.891329 | 3.27 | Pfam | 4-31 (31) | Show / Hide |
Range on Protein: 453-480 Range on HMM: 4-31/31 Sequence Identity: 32% (9 aa) LLRIALFDTSARVRLAAIKRLSITDEIL .| .| |....||.||.. |. |.. HLLKCLNDPDWEVREAACWCLGQLCEHC |
|||||||||
| HEAT | 88200.m00264.AA | HEAT | 487-511 | 28 | 10.785218 | 2.8 | Pfam | 7-31 (31) | Show / Hide |
Range on Protein: 487-511 Range on HMM: 7-31/31 Sequence Identity: 28% (7 aa) QLLNDADVDVKLAALKFVEEAASQN ..||| | .|..||.. . . ... KCLNDPDWEVREAACWCLGQLCEHC |
|||||||||
| FAT | 88200.m00264.AA | FAT | 1564-1614 | 14 | 0.000268 | 14.62 | Pfam | 210-265 (408) | Show / Hide |
Range on Protein: 1564-1614 Range on HMM: 210-265/408 Sequence Identity: 14% (8 aa) NILSGIHKRIAKESL-----SHDIFLERIKSQWAKGKREIALNKIEYLLKCYLSSP . |. ... .|. . . .. | .||.|... |..... ..|..... KTLKMLYTYDPSEEDWHPRAPPQWTYAYLKYMWATGQQQEAFQHLREFTSCHMQHD |
|||||||||
| HEAT | 88200.m00264.AA | HEAT | 1784-1814 | 19 | 49.697725 | 0.5 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 1784-1814 Range on HMM: 1-31/31 Sequence Identity: 19% (6 aa) LLPRFVDLLSKDKSSCRSIAKIVITRLSYDF .|| .. .|. . .. |. | ...|. . ILPHLLKCLNDPDWEVREAACWCLGQLCEHC |
|||||||||
| Kinase | 88200.m00264.AA | PIKK | 2097-2228 | 29 | 2.1e-16 | 56.56 | In-house | 154-290 (290) | Show / Hide |
Range on Protein: 2097-2228 Range on HMM: 154-290/290 Sequence Identity: 29% (40 aa) EIFKKLSENSLGDELLESIWRAMPAVSKWVRTGDKITMSYASNSMLCYVMRIEDRNPGNILIEKDSGNVCLIDYSSIFSKTKE-----EKVKFRMTKCVR |.| ....|...| . . || | | . | |||. .| |. . ||.| ||.| ...| . ||. .| . .. ||| ||.|.. EVFREQMQNTPPDMFKKWFWRKFPDPEIWWERRENYTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLPVPEKVPFRLTRNMV NLMDGANPFGMFQFSCEKIMEFLCEKRVLIMSQLKVS |.| | | .||..|. . ..| .|. ..| NAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF |
|||||||||
| Kinase | 88200.m00264.AA | ATR | 2117-2228 | 31 | 1.5e-15 | 49.04 | In-house | 152-267 (267) | Show / Hide |
Range on Protein: 2117-2228 Range on HMM: 152-267/267 Sequence Identity: 31% (36 aa) RAMPAVSKWVRTGDKITMSYASNSMLCYVMRIEDRNPGNILIEKDSGNVCLIDYSSIFSKTKE----EKVKFRMTKCVRNLMDGANPFGMFQFSCEKIME | | .| . . |||. .|. |.. . || ||||.| | . .|| || . .. | | ||.|. . . | |.| || || RRFPDPQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMM FLCEKRVLIMSQLKVS . ..| ||| .. CMRDHRDDIMSVWDCF |
|||||||||
| Kinase | 88200.m00264.AA | FRAP | 2087-2218 | 27 | 4.3e-09 | 29.68 | In-house | 95-231 (251) | Show / Hide |
Range on Protein: 2087-2218 Range on HMM: 95-231/251 Sequence Identity: 27% (38 aa) FSTLNKIQNIEIFKKLSENSLGDELLESIWRAMPAVSKWVRTGDKITMSYASNSMLCYVMRIEDRNPGNILIEKDSGNVCLIDYSSIF--SKTKE---EK .. | .. .|||. .| .|..| .| | | | | | || |.. . || | ||.... .| . ||. | ..| || YDHLPLMNKVEIFRYIMNNTKGEDLKKLLWLKSPNSEIWFERRTNYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFGDCFEVAMRREKFPEK VKFRMTKCVRNLMDGANPFGMFQFSCEKIMEFLCEKR . ||.|. | |. . | . || .|. . |.. IPFRLTRMLVNAMEACGIEGNYRNTCELVMKVIREHK |
|||||||||
| PI3_PI4_kinase | 88200.m00264.AA | PI3_PI4_kinase | 2039-2226 | 22 | 3.7e-07 | 28.15 | Pfam | 70-281 (300) | Show / Hide |
Range on Protein: 2039-2226 Range on HMM: 70-281/300 Sequence Identity: 22% (48 aa) PKIFPLCEDCGLIKINGMTETIEEIMTSFSAKRKHER---EIADEHLGLTRFSTLNKIQNIEIFKKLSENSLGDELLESIWRAMPAV-SKWVRTGDKITM ... |. ..||.| ..|. || . |.||. | .... .. .| ..| |.| . . . .. |.. |. | | . | . YRCIPTGPWCGMIEWVPNCTTFHEIPRTYMVKCKHKHFNKEHKMWMKMWPDWWHLMRMQKVEVFEMRIMKTPKPGLYQWFWKHNPDAYEEWWEARDNFVR SYASNSMLCYVMRIEDRNPGNILI--EKDSGNVCLIDYSSIFS------KTKEEKVKFRMTK------CVRNLM------DGANPFGMFQFSCEKIMEFL |.| ... |.... ||...||.. .|..|.. ||. .| | |.| || |. ..| | .|.|. .|..... | SCAGMCVVDYILGNGDRHNDNIMVKDDKTTGHLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRAL CEKRVLIMSQLK . .|.|. || RRHMNLCMNLLK |
|||||||||
| PI3Kc | 88200.m00264.AA | PI3Kc | 2000-2285 | 18 | 3.8e-07 | -51.53 | SMART | 1-336 (336) | Show / Hide |
Range on Protein: 2000-2285
Range on HMM: 1-336/336
Sequence Identity: 18% (64 aa)
RFLLFA-NDLYDDERFSIFVDVIRSMFVKD-ESF-VDFAPFCPKIFPLCEDCGLIKINGMTETIEEIMTSFSAKRK----------HEREIA--------
.... . || |.| .. .. . || |.. .|. . .|. |. ..||.| .||. .|. . ..| .. .
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDML-VPEIQKNMY
------DEHLGLTRFSTLNKIQNIEIFKKLSENSLGDELLESIWRAMPAVS-KWVRTGDKITMSYASNSMLCYVMRIEDRNPGNILIEKDSGNVCLIDYS
... . .. ......... | . . .. |.. |. | . .|. | | |.| .| .|.. | || ..||.. ...|.. ||.
MMIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG
SIFSKTKEEKVKF----------RMTKCVRNLMDG----ANPFGMFQFSCEKIMEFLCEKRVLIMSQLKVSFPENEM-IPYDDI--DRRMLGIDRDVD-D
||.. . |..| | |. ..| | . || |. |..... . . . |||. . . . .. . . | ..|.. .|
HIFGHG-PKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEM-MVYDPIMPCWRMMEKDIKYLRQRFRLDHL
ETRNVRDMVSK-----LIEIS--SENTNIYSMNFEWKPY
.... .. . ||| | | .| .| | |. |
SDEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
|
|||||||||
| Kinase | 88200.m00264.AA | ATM | 2133-2212 | 34 | 2.3e-05 | 12.66 | In-house | 141-224 (304) | Show / Hide |
Range on Protein: 2133-2212 Range on HMM: 141-224/304 Sequence Identity: 34% (29 aa) TMSYASNSMLCYVMRIEDRNPGNILIEKDSGNVCLIDYSSIFSKTK----EEKVKFRMTKCVRNLMDGANPFGMFQFSCEKIME | | | |. |.. . || |||| | . || | . | | | ||.|. . | |.| ||| || TRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTME |
|||||||||