Gene 92349.m00218 (T.vaginalis)

92349.m00218

Species: T.vaginalis
Alias: TvagK0879, 92349.m00218
External Links:
Annotation:

Classification

Group: Other
Family: NAK
Subfamily: NAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
92349.m00218.AA Protein None 551 None Fasta, JSON
92349.m00218.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of 92349.m00218.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92349.m00218.AA NAK 20-277 31 1.2e-73 245.24 In-house 1-299 (299) Show / Hide 
Range on Protein: 20-277
Range on HMM: 1-299/299
Sequence Identity: 31% (95 aa)

VTLKEKIGEGGYAWVFLAED----------QQKSVYALKYVKCV-DINKFNQFKKEAQFLQALPEHPHIVKIFAVDIN-EVD----MSIKFLFEYAPA-T
.| .....|||.. |.|..|          .   .|||| . |  | .. |. |.|..... |. |..||...  .|| ..|      . .| || .  .
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

CIGMM----T--DRPLSEQEILIFFHAICDAVAFLHSKNP--PILHRDLKPENILVA---PNGVPKLCDFGSATTSVLVANDPSEINR---IKDDIDNNT
 . .|    .   ....|.||| .|  .| .|...|. .|  || |||.|.||||      .| .|||||||.|| ..  .   |...   ..|.|  .|
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT

TQSYRAPEMIDLYNRIPISTPADVWALGCTLYKLVTRNEMFKP------EDTLAILQG--RITIPS--GCSPAFAQTIQACCQIDPSKRPTAAQIAASV
| .||||||.|||   || . .|.||||| |||.  ..  | .      . .|||. |  .. ||.    | .. . |... ..||..||. .|.   .
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase 92349.m00218.AA BIKE 20-276 39 9.5e-60 204.82 In-house 1-267 (267) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-267/267
Sequence Identity: 39% (107 aa)

VTLKEKIGEGGYAWVFLAEDQQKSVYALK--YVKCVDINKFNQFKKEAQFLQALPEHPHIVKIFAVDINEVDMSIK---FLFEYAPATCIGMMTDR---P
||. |.. |||.| |||. |..   .|||  ||.       |  ..| |... .  |  ||      || .   .     | ||  .  . || .|    
VTVEEQLAEGGFAMVFLVRDHKGNKCALKRMYVN--NEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWECMILMEYCRHQVVNMMNQRLQQG

--LSEQEILIFFHAICDAVAFLHSKNPPILHRDLKPENILVAPNGVPK--LCDFGSATTSVLVANDPSEINRIKDDIDNNTTQSYRAPEMIDLYNRIPIS
  . |||.|  |  .| ||..||    || ||||| ||||.  .| |   ||||||||. .|     . .| .|| |  .|| .||||||||||   .| 
QYFTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFLNPQKHG-VNYVKDEIEKYTTMCYRAPEMIDLYSGKEIT

TPADVWALGCTLYKLVTRNEMFKPEDTLAILQGRITIPSGC--SPAFAQTIQACCQIDPSKRPTAAQIAAS
| ||.||||| ||||      |  | .||| .|  |||.    |    . |.    .|. |||   |..  
TKADIWALGCMLYKLCFFCLPFG-ESQLAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDIYQVSHV
Kinase 92349.m00218.AA S_TKc 20-279 24 8.3e-50 172.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-279
Range on HMM: 1-231/231
Sequence Identity: 24% (68 aa)

VTLKEKIGEGGYAWVFLAEDQQ-KSVYALKYVKCVDINKFNQFKKEAQFLQALPEHPHIVKIFAVDINEVDMSIKFLFEYAPA---TCIGMMTDRP----
 .. .|||.|... |... .   . ..|.| .|       .....| | |.    ||.|||.. |  .    .. . .||..    .   .. .|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEQEILIFFHAICDAVAFLHSKNPPILHRDLKPENILVAPNGVPKLCDFGSATTSVLVANDPSEINRIKDDIDNNTTQSYRAPEMIDLYNRIPIST
   ..| ..  ... ||.|....||..  |.||||||||||.    . |.||||.|.                       |  |.|||..      . ..
RFPFPE-HARFYMYQICCALEYCHSHG--IIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL------GYGK

-PADVWALGCTLYKLVTRNEMFKPEDTLAILQGRITIPSGCSPAFAQTIQACCQIDPSKRPTAAQIAA-------SVLK
 ..|.|..||.|| ....   |    ... .  .|      || . . |. |.| ||.||||| .. .           
CKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92349.m00218.AA NAK-Unclassified 112-279 22 8.3e-44 150.76 In-house 125-405 (405) Show / Hide 
Range on Protein: 112-279
Range on HMM: 125-405/405
Sequence Identity: 22% (64 aa)

LSEQEILIFFHAICDAVAFLHSKNP--------------------------------------------PILHRDLKPENILVA----------------
..|||.| ..  .| ... .|.  |                                            |. |||.|.||.|.                 
FHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDIKIENVLFCNLRRPSNNNNNNNNNN

------------------------------------------PNGVPKLCDFGSATTSVLVANDPSEINRIKDDIDNNTTQSYRAPEMIDLYNRIPISTP
                                           || .|||||||...     .   |.. . |.|  .||  ||||||||||   ||.  
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIENRQEMQYLQDWINMHTTPQYRAPEMIDLYRCCPIDEK

ADVWALGCTLYKLVTRNEMFKPEDTLA-------ILQ--GRITIPSG--CSPAFAQTIQACCQIDPSKRPTAAQIAASVLK
 |.|||||.|||.   .  |  .. |.       ||   |. ..||    |  . . |. . . ||. ||.  |.   . .
IDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQVLNHICQ
Kinase 92349.m00218.AA STE 20-272 21 1.3e-39 137.59 In-house 1-350 (359) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-350/359
Sequence Identity: 21% (78 aa)

VTLKEKIGEGGYAWVFLAEDQ----------------QKSVYALKYVKCVDIN-----------------KFNQFKKEAQFLQALPE-HPHIVKIFAVDI
 .. ||||.|..  |..| .                 .. ..| | ..  . |                 ...|..|| .... .   ||.||| .   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NE---VDM--SIKFLFEYAPATCIGMMTD------RPLS----------EQEILIFFHAICDA-VAFLHSKNPPILHRDLKPENILVAPNGVPKLCDFGS
.|    .   ..    || .. ..  . .      .||.          |..| .. ..|. .  ..|||..  | |||.|| |||.      |||||| 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFGV

ATTSVL-VANDPSEINRIKDDIDN------NT-----TQSYRAPEMIDLYN---RIPISTPADVWALGCTL-------YKLVTRNEM---FKPEDTLAIL
..  .  .||. . .  .   ||.      ..     |. . |||.|.  .   . . .| .|.| ||||.       . . . . |   |   .  .. 
CGQLTDSMANI-Q-S-NN-I-IDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQ

Q----------GRITIPS-------------------GCSPAFAQTIQACCQIDPSKRPTAAQ
|          .  ..|.                    .|| | . |. |.|.||.||||| |
QQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 92349.m00218.AA Ciliate-E2 20-273 18 3.6e-37 125.13 In-house 1-359 (365) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-359/365
Sequence Identity: 18% (69 aa)

VTLKEKIGEGGYAWVFLAED-QQKSVYA--------------------LKYVKCVDINKFNQFKKEAQFLQALPE---------------HPHIVKIFAV
  . .|||.|... |..... ...  .|                    ....|..  |. .|.|.| . .. . .               ||.|.|.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

DINEVDMSIKFLFEYAPATCIG-MMTDR------------PLSEQEILIFFHAICD---------------AVAFLHSKNPPILHRDLKPENILVAPNGV
 ... | .| . .||.        . ..            ...|.||. ..  |..               |. .|||||. |.|||.||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

PKLCDFGSATTSVLVANDPSEINRIKDDIDNNT------------------------TQSYRAPEMIDLYN------RIPISTPADVWALGCTLYKLVTR
.|..||| ..      .. .. ...   . .                          |  | |||..   .      . . .. .|.|.||..|| ... 
IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

NEMFKPEDTLAILQGRITIP------------------SGCSPAFAQTIQA----CCQIDPSKRPT-AAQI
.  |       |.|. | .|                    .|.   . |.     . | ||.||.| . ||
KPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase 92349.m00218.AA CAMK 25-273 15 7.1e-37 115.84 In-house 1-419 (425) Show / Hide 
Range on Protein: 25-273
Range on HMM: 1-419/425
Sequence Identity: 15% (67 aa)

KIGEGGYAWVFLAEDQ-QK------------SVYALKYVKCVDIN----------------------------KFNQFKKEAQFLQALPE------HPHI
..|.|... |.|...   .              .| | ..   .                             .  ....| . .. | .      ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKIFAVDINEV-----------------DMSIKFLF---EYAPAT-----CIGMMTDR----------------PLSEQEILIFFHAICDAVAFLHSKNP
.|.. |  ..                  |. . . .   ||..       .  . ...                 ..|.|   .|. ||.||...||.| 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

PILHRDLKPENILVAPN-----------------GVPKLCDFGSATT-----SVLVANDPSEINRIKDD-----------IDNNTTQSYRA-PEMIDLYN
 | ||||||||||.  |                 .  |..||| |.      . .  .|. . . . ..            .   | .| | ||..    
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

-----------RIPISTPADVWALGCTLYKLVTRNEMFKPEDTL-----------------AILQGRIT-IPSG-----------------------CSP
           . ... ..|.|..|. || ...    |  ..                    |..|. . .|.                        .|.
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQ

AFAQTIQACCQIDPSKRPTAAQI
   . |. . | ||.||.|..|.
ECKDLIRKMLQVDPEKRMTIEQC
Kinase 92349.m00218.AA TKL 26-277 18 6.5e-36 125.63 In-house 1-364 (364) Show / Hide 
Range on Protein: 26-277
Range on HMM: 1-364/364
Sequence Identity: 18% (68 aa)

IGEGGYAWVFLAEDQQ---------KSVYALKYVKCVD--------------------------INKFNQFKKEAQFLQALPEHPHIVKIFAVDINEV--
||.||.. |. .. ..           . | |  |  .                          . .|..|..|   .     ||.||.. ......   
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------DMSIKFLFEYAPATC-IGMMTDRPLSEQEILIFFHAICDAVAFLHSKN------PPILHRDLKPENILVAPNGV--------------PKL
         .. . .  ||.|  .    ..      . .. . . |. ....|||.|      |||.|||||..||||  |.               .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

CDFGSATTSVLVANDPSEINRIK----------DDIDNNTTQSYRAPEMID---LYNR----------IPISTPADVWALGCTLYKLVTRNEMFKPED--
|||| ...     |.    . ..            .    |  . |||...    |.            . |. .||.. |  |. ..|| . .. ..  
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------TLAILQG-RITIP------------SGCSPAFAQTIQACCQIDPSKRPTAAQIAASV
             .... | | .||            . | | ... .| |.. ||.|||.. .|    
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 92349.m00218.AA GAK 111-277 38 8.5e-36 116.37 In-house 104-277 (277) Show / Hide 
Range on Protein: 111-277
Range on HMM: 104-277/277
Sequence Identity: 38% (69 aa)

PLSEQEILIFFHAICDAVAFLHSKNPPILHRDLKPENILVAPNGVPKLCDFGSATTSVLVANDP--SEINR--IKDDIDNNTTQSYRAPEMIDLYNRIPI
|.|   .|  |   | ||...||  ||| |||.| || |.  ..  |||||||||| ..   |.  |   |  . | .  .||  || |||.|||   ||
PFSCDCVLRIFYQMCRAVQHMHSQKPPIIHRDIKIENFLIGNQKTIKLCDFGSATTKSHYP-DYSWSAQKRSMVEDEMFRHTTPMYRSPEMCDLYSNWPI

STPADVWALGCTLYKLVTRNEMFKPEDT--LAILQGRIT--IPS--GCSPAFAQTIQACCQIDPSKRPTAAQIAASV
    |.||.|| || .  |   |  ||   |.|  |  .  ||       .|.  | || | .|  |...|..    
GHKQDIWAMGCMLYFMCYRQHPF--EDGAKLRIINGNYMKPIPPQDNQYMCFHDLIRACLQVNPDERLDIAMVVEYM
Kinase 92349.m00218.AA Ciliate-E2-Unclassified 21-273 20 2e-33 113.28 In-house 2-346 (352) Show / Hide 
Range on Protein: 21-273
Range on HMM: 2-346/352
Sequence Identity: 20% (73 aa)

TLKEKIGEGGYAWVFLAED-QQKSVYALKYVKCVDINK-------FNQFKKEAQFLQAL----------------PEHPHIVKIFAVDINEVDMSIKFLF
.. ..||.||.. |..... .|| .||.|| | . |.|         ... |.. .. .                  |||....  ... . .  | .  
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYAPA----TCIG---------------MMTDRPLSEQEIL-----IFFHAICDAVAFLHSKNPPILHRDLKPENILVAPNG---VPKLCDFGSATTS-V
||..      .|                |.... ..||...      .|  |...  .||.||  |.|||.||||||.  ||    .|..|||..  .  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

LVANDPSE----INRIKDDIDNNTTQSYR------APEMIDLYNRIPIS-TPADVWALGCTLYKLVTRNEMFKP--------------------EDTLAI
 . .|  .    ....|... . ......      |||...  |    .   .|.|.||. || ... .  |.                     .    |
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LQGRITIPS--------GCSPAFA----QTIQACCQIDPSKRPTAAQI
.|. | .|.        . ||  .    . .| . . .|.||.|. ||
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Kinase 92349.m00218.AA Pkinase 20-164 25 4.7e-33 117.94 Pfam 1-159 (293) Show / Hide 
Range on Protein: 20-164
Range on HMM: 1-159/293
Sequence Identity: 25% (42 aa)

VTLKEKIGEGGYAWVFLAEDQQKSV-YALKYVKCVDINK--FNQFKK--EAQFLQALPEHPHIVKIFAVDINEVDMSIKFLFEYAPAT--CIGMM-----
 ....|||.|... |... ..  .  .|.| .| .....    .  .  |.| .. |  ||.||... .  .. ..   . .||.. .  ..  .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDYIST

-TDRPL--SEQEILIFFHAICDAVAFLHSKNPPILHRDLKPENILVAPNGVP----KLCDFGSA
  ....  ||.|.  ..  |. .....||.   |.||||||||||.  ||..    |.||||.|
WRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase 92349.m00218.AA CMGC 20-233 18 3e-27 85.83 In-house 1-347 (513) Show / Hide 
Range on Protein: 20-233
Range on HMM: 1-347/513
Sequence Identity: 18% (63 aa)

VTLKEKIGEGGYAWVFLAEDQQ---------------KSVYALKYVKCVDINKFNQ-------FK----KEAQFLQAL----------------PEHPHI
 .  .||||| |. |. . |..               . ..|.| .| .      .       |.     | ..|. |                . |..|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VKIFAVDINEVDM---------------SIKFLFEYAPATCIGMMTD----------RPLSEQE------------ILIFF------HAICDAVA--FLH
||.. .   . .                .. . ||| . .  ... .          .|||| .            |  |.      . |. ...  ..|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SKNPPILHRDLKPENILVAPNGVP--------------------KLCDFGSATTSVLVANDPSEINR------------IKDDIDNNTTQSYRAPEMIDL
|..  |.||||||||||. .|.                      |.||||.|.      ... . ..             .   ..  |  ||||| .  
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

YN-------RIPISTPADVWALGCTLYKLVTR--------NEMFKPED
.            .|| |.|..|| .. ..|.          .|....
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHS
Kinase 92349.m00218.AA Pkinase 192-277 21 8.1e-15 53.47 Pfam 177-293 (293) Show / Hide 
Range on Protein: 192-277
Range on HMM: 177-293/293
Sequence Identity: 21% (26 aa)

YRAPEMIDLYN-RIPISTPADVWALGCTLYKLVTRNEMFKPE------DTLAILQGRIT------IPSGCS-------------------PAFAQTIQAC
|.|||     . . ......|.|..||.|| .....  |. .      | ..... .        .|  ||                   ... . |  |
YMAPEV---IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

CQIDPSKRPTAAQIAAS--V
.. ||.|||||.||  .  .
LCKDPKKRPTAEQILQHPWF
Kinase 92349.m00218.AA TyrKc 20-277 23 3.2e-14 7.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-277
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

VTLKEKIGEGGYAWVFLAEDQQKSVYALKYVKCVDINKFNQFKKEAQFLQAL-PEHPHIVKIFAVDINE-----VDMSIKFLFEYAPA----TCIGMMTD
.||..|.||| .  |....     | | | .|         | .||. .  | ..||.||....| . .      .  .  ..||.|       .    .
ITLGKKLGEGAFGEVYKGTWK-IQV-AVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RPLSEQEILIFFHAICDAVAFLHSKNPPILHRDLKPENILVAPNGVPKLCDFGSATTSVLVAND-PSEINRIKDDIDNNTTQSYR--------APEMIDL
. |. .. | | . |..  ..||||  .. ||||   |.||. |.. | .|||    |  . .|  .     || ..  .... .        ||| |  
K-LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFG---LSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECI--

YNRIPISTPA-DVWALGCTLYKLVTRNEMFKPE-----DTLA-----ILQG-RITIPSG--------CSPAFAQTIQACCQIDPSKRPTAAQIAASV
  .  . |.. |||. | ... . |. ..  |.      . .     . || |  .|          |...  | .. |.. ||..||| ..|    
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 92349.m00218.AA NAK-Unclassified 20-81 25 3.4e-08 24.42 In-house 1-77 (405) Show / Hide 
Range on Protein: 20-81
Range on HMM: 1-77/405
Sequence Identity: 25% (20 aa)

VTLKEKIGEGGYAWVFLAE--------D------QQK-SVYALKYVKCVDINKFNQFKKEAQFLQALPEHPHIVKIF
.|    ..||| . |.|.         |          ..|.|| . | | .  |  | |    . .  ||.|||..
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYI
Kinase 92349.m00218.AA Pkinase_Tyr 240-277 26 1.6e-05 19.37 Pfam 233-270 (270) Show / Hide 
Range on Protein: 240-277
Range on HMM: 233-270/270
Sequence Identity: 26% (10 aa)

GRITIPSGCSPAFAQTIQACCQIDPSKRPTAAQIAASV
.|  .| .|..   . .. | . ||..||| ..|    
YRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 92349.m00218.AA GAK 22-48 46 0.001896 7.23 In-house 3-30 (277) Show / Hide 
Range on Protein: 22-48
Range on HMM: 3-30/277
Sequence Identity: 46% (13 aa)

LKEKIGEGGYAWVFLAEDQQ-KSVYALK
 .  | |||.| |..| | |    ||||
VRCVIAEGGFAFVYVAQDVQTGREYALK
Kinase 92349.m00218.AA CMGC 248-273 38 0.013599 3.3 In-house 482-507 (513) Show / Hide 
Range on Protein: 248-273
Range on HMM: 482-507/513
Sequence Identity: 38% (10 aa)

CSPAFAQTIQACCQIDPSKRPTAAQI
|.| .   .. . |.||.||.||.|.
CDPQAIDLLKKMLQYDPDKRITAEQA
Kinase 92349.m00218.AA Pkinase_Tyr 124-162 48 0.033029 8.1 Pfam 120-156 (270) Show / Hide 
Range on Protein: 124-162
Range on HMM: 120-156/270
Sequence Identity: 48% (19 aa)

ICDAVAFLHSKNPPILHRDLKPENILVAPNGVPKLCDFG
|... ..|.|||  . ||||   |.||. |.| | ||||
IAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFG
Kinase 92349.m00218.AA Pkinase_Tyr 20-79 26 0.185723 5.56 Pfam 1-68 (270) Show / Hide 
Range on Protein: 20-79
Range on HMM: 1-68/270
Sequence Identity: 26% (18 aa)

VTLKEKIGEGGYAWVFLAEDQ-----QKSVYALKYVKCVDINK---FNQFKKEAQFLQALPEHPHIVK
.|. .|.||| .  |....       .|   | | .|     .      | .||. .  |. ||.||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVR