96955.m00161

Species: T.vaginalis
Alias: 96955.m00161, TvagK0351
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
96955.m00161.AA Protein None 968 None Fasta, JSON
96955.m00161.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of 96955.m00161.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96955.m00161.AA TKL 201-445 23 3.2e-80 272.81 In-house 1-364 (364) Show / Hide
Range on Protein: 201-445
Range on HMM: 1-364/364
Sequence Identity: 23% (88 aa)

IAQGGYAIVHLAKLRATN--------EELAIKELKPANLKPRTV-------------------------GYLKREIDSMLALDHPNLLKLAGVTITAP--
| .||...|. .|.| ..        .. |.| .|  | . .|                            ...|| .|. |.|||.... |. .  |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIATGFLPNGDLYEILHGKNQKMKKPMLLSQISIDVARGLEYVHANH--------MVHRDLKPPNILMDKNWR--------------
            .|| . . |.|.|...||        . .. ....|.|||..| |...        ..|||||..||| |.||.              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AVICDFGLARYIGP--NMTC--------------------ELGTAQWMAPELFSGD---------------GSYDTCVDVYAYGILLWELFTQQMPYTQM
. ||||||.| . .  ||..                    . || .|||||.. |.               ..|.. .|||..||.|||..| . || ..
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

RLLQIA---------VGVLKEKMRPQFP------------PNSDPIYKNLIQSCWAHKKSARPTMKDVRTLL
   ..          ..| ....||  |            |. .| .|.|.| ||.|. ..||.....   |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 96955.m00161.AA Dicty4 239-447 35 8.3e-58 191.43 In-house 45-277 (277) Show / Hide
Range on Protein: 239-447
Range on HMM: 45-277/277
Sequence Identity: 35% (82 aa)

LKREIDSMLALDHPNLLKLAGVTIT---AP--FCIATGFLPNGDLYEILHG----KNQKMKKP-MLLSQ---ISIDVARGLEYVHA-N-HMVHRDLKPPN
...|.. |  . |||.... |  .    .|  .|| | ..| |.||..||     . |. |..  |  .   . .|.|||. . |. |   .|||||. |
FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHN

ILMDKNWRAVICDFGLAR----YI--GPNMTCELGTAQWMAPELFSGDGSYDTCVDVYAYGILLWELFTQQMPYT--QMRLLQIAVGVLKEKMRPQFPPN
.|.|||||. .|||||..     .  . |..   ||. |||||   .. .|.  .||| .||.|||..| | ||    | . |.. .|  .|.||  |..
LLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQ-PYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDW

SDPIYKNLIQSCWAHKKSARPTMKDVRTL--LET
 .| .| ||| || |  . ||... .     ||.
CPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 96955.m00161.AA TKL-Unique 199-445 31 8.4e-57 195.02 In-house 3-290 (290) Show / Hide
Range on Protein: 199-445
Range on HMM: 3-290/290
Sequence Identity: 31% (90 aa)

ENIAQGGYAIVHLAKLRATNEELAIKELKP-ANLKPRTVGYLKREIDSMLALD-HPNLLKLAGVTI----TAP-FCIATGFLPNGDLYEILH-------G
. | .|||. |  .| | .  . ||| ..| . . .. .  ...|.  |  |. |||.... |...    ..| .|| . ..| | ||. ||        
NKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

KNQKMKKPMLL-SQISIDVARGLEYVHANH--MVHRDLKPPNILMDKN-----WRAVICDFGLARYIG--PNMTCE----------LGTAQWMAPELFSG
 |...| .|..  .. ||.|.|..| | .   . |||||..|.| | |     |.. ||||||..      .||            .|...|||||....
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

D-GSYDTCVDVYAYGILLWELFTQQM------PYTQMRLLQIA--VGVLKEKMRPQFPPNSDPIYKNLIQSCWAHKKSARPTMKDVRTLL
    |.. .|||..|| |||..| .       ||  |   |..  | . .|. ||  |..  ..|..||| ||.|  | ||.  .... |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 96955.m00161.AA Dicty4-Unclassified 249-445 36 2.2e-54 184.63 In-house 55-263 (263) Show / Hide
Range on Protein: 249-445
Range on HMM: 55-263/263
Sequence Identity: 36% (76 aa)

LDHPNLLKLAGVTITAP------FCIATGFLPNGDLYEILHGKNQKMKKPMLLSQ-----ISIDVARGLEYVHANHMVHRDLKPPNILMDKNWRAVICDF
. ||||.|. |  | .|      .|| . |.. | | |. | |    ..|. |       . .|.|.|. . |   ..|||.|  ||||||.  . | ||
IQHPNLVKCYGYCI-NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADF

GLARYI--GPNMTCELGTAQWMAPELFSGDGSYDTCVDVYAYGILLWELFTQQMPYTQMR-LLQIAVGVLKEKMRPQFPPNSDPIYKNLIQSCWAHKKSA
|..| |    |||   ||  | .||   .  ||    ||| |...|.|| |   ||      . .|  |   |.||. | | |. .| ||  ||      
GISRVIDFNFNMTTIAGTPKWESPECLMHE-SYNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNK

RPTMKDVRTLL
|||| ..   |
RPTMNQIIQYL

Kinase 96955.m00161.AA MLK 195-445 26 3.5e-53 182.81 In-house 1-291 (291) Show / Hide
Range on Protein: 195-445
Range on HMM: 1-291/291
Sequence Identity: 26% (76 aa)

EITDENIAQGGYAIVHLAKLRATN---EELAIKELKPANLKPRTVGY-----LKREIDSMLALDHPN----LLKLAGVTITA-P-FCIATGFLPNGDLYE
  . | |  |..  |.... |...    ..|.|. .        . |     ...|.     |.|||      .. || .   . ||| . ....| ||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ILHG-KNQKM-----------KKPMLLSQISIDVARGLEYVHANH---MVHRDLKPPNILMD------KNWRAVICDFGLARYIGPN---MTCELGTAQW
.||| ... |            .. .. ... ..|||..| |..     .|||||..||| |      ..  ..|||||..| .  .   |..  ||. |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPELF--SGDGSYDTCVDVYAYGILLWELFTQQMPYT-QMRLLQIAVGVLKEKMRPQFPPNSDPIYKNLIQSCWAHKKSARPTMKDVRTLL
|||| .  .  . |.  .||. .|..|||..| ..||   .  ..|| .|  .. ||  |.. ... |.|.. ||  . . ||... . . |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 96955.m00161.AA LRRK 195-447 25 4.5e-53 182.65 In-house 1-351 (351) Show / Hide
Range on Protein: 195-447
Range on HMM: 1-351/351
Sequence Identity: 25% (89 aa)

EITDENIAQGGYA-IVHLAKLR--------------------------ATNEELAIKELKP--------------------------------ANLKPRT
 .  | | .||.. .|. ||.|                          .  .. ||| ..                                 .  ..| 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

VGYLKREIDSMLALDHPNLLKLAGVTITAPFCIATGFLPNGDLYEILHGKNQKM------K-KPMLLSQISIDVARGLEYVHANH--MVHRDLKPPNILM
   . .|.  |  |.|||...| |..|  |.|... ..|.||||. || | |        . ..||. .|....|.|.|| | ..   .|||||.||||.
FREFRHEVWIMSHLNHPNIVSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---D---------KNWRAVICDFGLAR--YIGPN--MTCELGTAQWMAPELFS--GDGSYDTCVDVYAYGILLWELFTQQ-MPYTQMR------LLQIAV
   .          .  | |.|||. |  .. ..      .|. .|||||     |. .|.. ||.|..|..|||| | |  |. ..       .  .  
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

GVLKEKMRPQFPPN-SDP-----IYKNLIQSCWAHKKSARPTMKDVRTLLET
   .|. || .|..   |      |..|||.||.|.   ||.. ..   |..
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 96955.m00161.AA S_TKc 195-451 23 4.5e-50 173.59 SMART 1-231 (231) Show / Hide
Range on Protein: 195-451
Range on HMM: 1-231/231
Sequence Identity: 23% (62 aa)

EITDENIAQGGYAIVHLAKLRATNEELAIKELKPANLKPRTVGYLKREIDSMLALDHPNLLKLAGVTITAPFCIATGFLPN--GDLYEILHGKNQ----K
    . | .|... |.... . |... |||..|           ..|||. .   .|||. || .|  .  ... . ....  |||..... ..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

MKKPMLLSQISIDVARGLEYVHANHMVHRDLKPPNILMDKNWRAVICDFGLARYIGPNMTCELGTAQWMAPELFSGDGSYDT-CVDVYAYGILLWELFTQ
   .     .   ....||| | .. .|||||| |||.|.  .  |||||||| .    |   ||  .||||..    .|..  .|... |..|.|... 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

QMPYTQMRLLQIAVGVLKEKMRPQFPPNSDPIYKNLIQSCWAHKKSARPTMKDVRT---LLETGEYV
. |.    . ..   ..            .|  |..|. |.    . |||  .. .   .    ...
YPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 96955.m00161.AA TK 209-445 16 8.3e-47 154.49 In-house 18-486 (486) Show / Hide
Range on Protein: 209-445
Range on HMM: 18-486/486
Sequence Identity: 16% (77 aa)

VHLAKLRATN-------------------------EELAIKELKP-ANLKPRTVGY--------------LKREIDSML--ALDHPNLLKLAGVTITA--
|.....|  |                         .. |.| ||. ..  ..                  . .|.  |.  ...|||...| ||      
VYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEP

-----------PFCIATGFLPNGD----LYEILHGKNQKMKKPMLLSQ----------------------------------------------------
           |..| . . |.||    | . |. .  |....   ..                                                    
KPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDL

---------------------ISIDVARGLEYVHAN------HMVHRDLKPPNILMDKNWR-----------AVICDFG--------LARYIGPNMTCEL
                     .. ..|.|.|| |..      ..|||||   |.| ..| .           . |.|||        |||.|...     
LQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYR

GTAQ-----------------------------WMAPELFSG--------DGSYDTCVDVYAYGILLWELFT--QQMPYTQMRL--------LQIAVGVL
 . .                             ||||| . .        .| . |  ||...|.|.||.||  |...| .|          .|  .  |
KSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYL

KE--------------KMRPQFPPNSD--------------PIYKNLIQSCWAHKKSARPTMKDVRTLL
..              .||.  ||.                ..|  |.|.||... . |||.....  |
RRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 96955.m00161.AA Dicty5 298-449 38 9.7e-45 151.91 In-house 109-260 (260) Show / Hide
Range on Protein: 298-449
Range on HMM: 109-260/260
Sequence Identity: 38% (59 aa)

ISIDVARGLEYVHANHMVHRDLKPPNILMDKNWRAVICDFGLAR--YIGPNMTCELGTAQWMAPELFSGDGSYDTCVDVYAYGILLWELFTQQMPYTQMR
. ||.|......|    .|||||  |.|  .|| . | |||  |      .|| ..||  |||.||| | . |.  .|||..|| |||.||.  ||  . 
MAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQP-YHQKCDVYSFGIVLWEMFTRKEPYDNIN

LLQIAVGVLKEKMRPQFPPNSDPIYKNLIQSCWAHKKSARPTMKDVRTLLETGE
   |.| | |   ||  |.     . ||| .||  | . ||. | .   .|   
NWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 96955.m00161.AA DRK 220-447 33 1.9e-43 145.03 In-house 24-258 (258) Show / Hide
Range on Protein: 220-447
Range on HMM: 24-258/258
Sequence Identity: 33% (80 aa)

ELAIKELKPANLK-PRTVGYLKREIDSMLALDHPNLLKLAGV-TITAPFCIATGFLPNGDLYEILHGKNQKMKKPMLLSQISIDVARGLEYVHANH--MV
. |.| |.  |      .  ..|||. |  | |||     |  ..    || . ..| | || |||    .|  | .. |. .|.|.|. | |      .
QVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMK-QMMFDCAKGMIYLHCCNPIII

HRDLKPPNILMDKNWRAVICDFGLAR------YIGPNMTCELGTAQWMAPELFSGDGSYDTCVDVYAYGILLWELFTQQMPYTQMRLLQIAVGVLKEKMR
|||||  | | | .|.  . ||||.         .  ||   ||  | |||    .. |    ||| ..| |||. | | ||  |  .|.   | ...||
HRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVLRNQR-YTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMR

PQFPPNSDPIYKNLIQSCWAHKKSARPTMKDVRTLLET
|  |..  | |  |.. ||    . ||.| ..   || 
PPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA

Kinase 96955.m00161.AA TyrKc 195-445 26 5.1e-42 146.84 SMART 1-280 (280) Show / Hide
Range on Protein: 195-445
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

EITDENIAQGGYAIVHLAKLRATNEELAIKELKPANLKPRTVGYLKREIDSMLAL--DHPNLLKLAGVTIT--------APFCIATGFLPNGDLYEILHG
   .. .  | . .|......   .. |.| ||.       .  . ||.  |  |  .|||...| || ..         | .| . . |.||| . |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KNQKMKKPMLLSQISIDVARGLEYVHANHMVHRDLKPPNILMDKNWRAVICDFGLARYIGPN--------MTCELG--TAQ------WMAPELFSGDGSY
.  | . . ||| .....|.| || | .. .||||   |.| ..| .. |.||||.|.|.          .    .   .       ||||| .  .| .
HRPKLCMKDLLS-FCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKF

DTCVDVYAYGILLWELFTQ-QMPYTQM----RLLQIAVGVLKEKMRPQFPPN---------SDPIYKNLIQSCWAHKKSARPTMKDVRTLL
 |  ||...|...||.||  |.||  |       | ..  .|. .|.  |||         .| .|. ....||... . |||..... ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF

Kinase 96955.m00161.AA Pkinase 195-445 23 4e-40 142.95 Pfam 1-293 (293) Show / Hide
Range on Protein: 195-445
Range on HMM: 1-293/293
Sequence Identity: 23% (69 aa)

EITDENIAQGGYAIVHLAKLRATNEELAIKELKPANLKPRTVGYLKR--EIDSMLALDHPNLLKLAGVTI-TAPFCIATGFLPNG----DLYEILH-GKN
  . . | .|... | ... . |... |.|..|  . |.    .. |  ||  |. |.||| ..| ..       .. . ....|    ||.....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKM-KKPMLLSQISIDVARGLEYVHANHMVHRDLKPPNILMDKNWRA----VICDFGLAR---YIGPNMTCELGTAQWMAPELFSGDGSYDTCVDVYAYG
 ..   .  .  .   ..||||| |..  .|||||| |||.|.|        |||||||.   | .. ||   ||  .||||.  |.  |.. ||....|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

ILLWELFTQQMPYTQM------RLLQIAVGVLKEKMRPQFPPNSD-------------------PIYKNLIQSCWAHKKSARPTMKDVRTL--L
..|.|... . |. .       . .|. . ... . . ..|  ..                   .  | .| .|.. . . ||| ...     .
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 96955.m00161.AA TKL-ciliate2 196-446 29 4.8e-39 127.61 In-house 2-273 (273) Show / Hide
Range on Protein: 196-446
Range on HMM: 2-273/273
Sequence Identity: 29% (82 aa)

ITDENIAQGGYAIVHLAKLRATNEELAIKELKPANLKPRTVGYLKREIDSMLALDHPNLLKLAGVTITAP-FCIATGFLPNGDLYEILHGKNQKMKKPML
 ... |. ||| |.  || | .    |.|  |    . ...     | . | || |||.    |     | |||   .   | |. .|  .. ..     
EIQNKITEGGYGIIYKAKWREI--VVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTW-ED

LSQISIDVARGLEYVHANH--MVHRDLK--------------------PPNILMDKNWRAVICDFGLARYI--GPNMTCELGTAQWMAPELFSGDGSYDT
  .| .|.|||  |.|. .  ..|||||                      |.|.| | |  . |||  |       ||  .|| ||||||  .    |  
RRRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAF-YYTE

CVDVYAYGILLWELFTQQMPYTQMRLLQIAVGVLKEKMRPQFPPNSDPIYKNLIQSCWAHKKSARPTMKDVRTLLE
  ||..|.|.|||.     ||  ..   .|. |... .||  | |  | . .|.| ||   .  ||.. ..   ||
KADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE

Kinase 96955.m00161.AA Pkinase_Tyr 196-445 27 6.9e-39 132.33 Pfam 2-270 (270) Show / Hide
Range on Protein: 196-445
Range on HMM: 2-270/270
Sequence Identity: 27% (74 aa)

ITDENIAQGGYAIVHLAKLR----ATNEELAIKELKPANLKPRT--VGYLKREIDSMLAL-DHPNLLKLAGVTI--TAP--FCIATGFLPNGDLYEILHG
. .. . .| .  |......     |. . |.| ||. .  ..      . ||.  |  | .|||...| || .    |   .| . . |.|||.. |. 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K---NQKMKKPMLLSQISIDVARGLEYVHANHMVHRDLKPPNILMDKNWRAVICDFGLARYI-----G-PNMTCELGTAQWMAPELFSGDGSYDTCVDVY
.   .|. . .. | |.....|.|.|| ......||||   |.| ..|  . ||||||||.|          .       ||||| ..    . |  ||.
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

AYGILLWELFT-QQMP-YTQMRLLQIAVGVLKEKMRPQFPPNSDPIYKNLIQSCWAHKKSARPTMKDVRTLL
..|.|.||.||  ..| |  |   ..   . ..  |   |.|  .   .|...||... . |||.....  |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL