Gene 89678.m00207 (T.vaginalis)

89678.m00207

Species: T.vaginalis
Alias: TvagK0783, 89678.m00207
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
89678.m00207.AA Protein None 398 None Fasta, JSON
89678.m00207.kin_dom Protein Kinase Domain None 125 None Fasta, JSON

Protein domain

Protein domains of 89678.m00207.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89678.m00207.AA Ciliate-E2 83-206 18 2e-18 59.83 In-house 111-296 (365) Show / Hide 
Range on Protein: 83-206
Range on HMM: 111-296/365
Sequence Identity: 18% (37 aa)

ILMDYIPGNTLTKLI-------------NGGYVSNRVKRLYMLEIFY---------------AIAYQLTLMRENG-IKHRDFKPDNIVVDGDMIPHIIDW
. |.|. |..| ..|               .| . .  . .| .|..               |. |    . ... | ||| ||.||..     . |||.
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEY----LHSKNNIIHRDIKPENILF-----IKIIDF

DDST-----------NRFSLSINEHH-----------------------GTIPFAAPEIFSGQRK----------CESDIFSFGAIMFNMITECYPF
  |.           .. .  . . .                       || .. ||||..|.             ..||.|.| |.. |..  .||
GLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF
Kinase 89678.m00207.AA Ciliate-E2-Unclassified 85-213 20 7e-17 55.1 In-house 100-277 (352) Show / Hide 
Range on Protein: 85-213
Range on HMM: 100-277/352
Sequence Identity: 20% (38 aa)

MDYIPGNTLTKLIN------------------GGYVSNRVKR-----LYMLEIFYAIAYQLTLMRENGIKHRDFKPDNIVVDGDM---IPHIIDWDDST-
|.|..|..| . |.                  .  .. .  .      |. .|  .. |   | ..|.| ||| ||.||..| ..    . |||.  |  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEY---LHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

------------NRFSLSINEHH----GTIPFA----APEIFSG-QRK----CESDIFSFGAIMFNMITECYPFASAYKTK
            ....  ....     ||. .     |||.. | .       ..||.|.| |.. |..  ||| .  ...
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQ
Kinase 89678.m00207.AA CAMK 127-206 18 4.8e-15 44.23 In-house 197-334 (425) Show / Hide 
Range on Protein: 127-206
Range on HMM: 197-334/425
Sequence Identity: 18% (25 aa)

ENGIKHRDFKPDNIVVDGDM-----------------IPHIIDWDDSTNRFSLS-------------------------INEHHGTIPFAA-PEIFSG--
...| ||| ||.|| .| ..                    |||.  ..  .. .                          ..  || ...| ||...|  
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

-----------QRK--CESDIFSFGAIMFNMITECYPF
           ..    ..|. | | |.. | . ..||
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
S_TKc 89678.m00207.AA S_TKc 13-320 15 1e-12 9.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-320
Range on HMM: 1-231/231
Sequence Identity: 15% (52 aa)

VQEIYQADNGSNGACW--ILKIDDHYRVLKRLFNRSGIRISEMFEKEMQFQI---PLSPLYYDNSQNHPGERFNWILMDYIPG---NTLTKLINGGY---
 . . .   |. | ..  . | ....  .|..         |....|.|      |    .||  |.     . .. |.|..|   . .. . . |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKKHHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VSNRVKRLYMLEIFYAIAYQLTLMRENGIKHRDFKPDNIVVDGDMIPHIIDWDDSTNRFSLSINEHHGTIPFAAPEIFSGQRKCESDIFSFGAIMFN
    .  . | || .|. |..|    . ..|| ||| ||.|| .|      |.|   ..       .   ||  . |||.. |  ||..|. |.| |.. 
RFPFPE-HARFYMYQICCALEY----CHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYE

MITECYPFASAYKTKAGLQSLTSQFPELQLPYLALTLDTLADFEQMDESEKSSAWSTVVSFVEPILIELIKAGARDDYINNEKFQNDPFNKKISELIELC
|.. . ||      .. .. .                                                                     .   ..|. |
MLCGYPPFP---QMQMMFKKIG-------------------------------------------------------------------SPEAKDFIRKC

CKQEPFSRIRPEDLQD-----RIDTLA
.. .|  |.   ..       ...   
LQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 89678.m00207.AA Pkinase 82-206 24 3.5e-10 37.1 Pfam 76-212 (293) Show / Hide 
Range on Protein: 82-206
Range on HMM: 76-212/293
Sequence Identity: 24% (35 aa)

WILMDYIPGN----TLTKLIN---GGYV--SNRVKRLYMLEIFYAIAYQLTLMRENGIKHRDFKPDNIVVDGDMIP----HIIDWDDST---NRFSLSIN
.. |.| .|      |  .|    .| .  | .. . ||..|. ...|    . ..|| ||| ||.|| .| .. .    .|.|.  .    .  .   .
YMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEY----CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT

EHHGTIPFAAPEI--FSGQRKCESDIFSFGAIMFNMITECYPF
   ||....|||.  ..     ..|..|.| |.. |..   ||
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase 89678.m00207.AA CAMKL 169-206 38 2.4e-08 22.59 In-house 195-236 (297) Show / Hide 
Range on Protein: 169-206
Range on HMM: 195-236/297
Sequence Identity: 38% (16 aa)

GTIPFAAPEIFSG--QRKC--ESDIFSFGAIMFNMITECYPF
|. |..|||||.|  .. .  . || | | |...|..  .||
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF
Kinase 89678.m00207.AA TKL 132-207 19 1.5e-07 23.29 In-house 163-290 (364) Show / Hide 
Range on Protein: 132-207
Range on HMM: 163-290/364
Sequence Identity: 19% (25 aa)

HRDFKPDNIVVDGDMI--------------PHIIDWDDSTNRFSLSINEH---------------------HGTIPFAAPEIFSGQRK------------
||| |..|| || ..               . | |   |.. .  . ...                      ||. . |||.. || .            
HRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCK

-----CESDIFSFGAIMFNMITECYPFA
       .|..||| ... ..| | |..
GFEYSEKCDVYSFGIVLWEILTRCRPYY
Kinase 89678.m00207.AA Ciliate-E3 170-200 37 1.5e-07 19.9 In-house 171-202 (202) Show / Hide 
Range on Protein: 170-200
Range on HMM: 171-202/202
Sequence Identity: 37% (12 aa)

TIPFAAPEIFS-GQRKCESDIFSFGAIMFNMI
|. .||||.   .| . |||. | ||..  ..
TPFYAAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase 89678.m00207.AA STE 82-227 18 2e-07 22.44 In-house 113-304 (359) Show / Hide 
Range on Protein: 82-227
Range on HMM: 113-304/359
Sequence Identity: 18% (36 aa)

WILMDYIPGNTLTKLINGGYVSNRVKRLYM-------LEIFYAIAYQ-----LTLMRENGIKHRDFKPDNIVVDGDMIPHIIDWDDSTNRFS--------
|| | |..| .|...|.  |  ..   .          ..  .|..|     | .  ...| ||| ||.|| .       ..|   ...  .        
WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSN

----------LSINEHHGTIPFAAPEIFSGQRKC-------ESDIFSFGAIMFNMITECYPFASAYKTKAGLQSLTS---------------QFPELQ
             |   ||  . |||. ......        .|| |.|  .  |.| ..|..  . ..| .. ...               . | |.
NIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLP
Kinase 89678.m00207.AA TKL-Unique 128-206 24 2.3e-07 22.24 In-house 129-234 (290) Show / Hide 
Range on Protein: 128-206
Range on HMM: 129-234/290
Sequence Identity: 24% (26 aa)

NG--IKHRDFKPDNIVVDGD-----MIPHIIDWDDSTNRFSL---SINEH--------HGTIPFAAPEIFSG---QRKCESDIFSFGAIMFNMITECY--
..  | ||| |. |. || .     .   |.|   |... .    ..|||         |..  .|||....   |. . ||..|||...  ..| .   
CEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITK

----PF
    |.
TYKKPY
Kinase 89678.m00207.AA AGC 83-152 27 2e-05 8.4 In-house 110-198 (395) Show / Hide 
Range on Protein: 83-152
Range on HMM: 110-198/395
Sequence Identity: 27% (25 aa)

ILMDYIP----------G-NTLTKLI---NGGYVSNRVKRLYMLE-------IFYAIAYQLTLMRENGIKHRD-FKPDNIVVDGDMIPHIID
..|.|.|          |  ... |    . |. .  . | |. |       |  |. |   | ...|| |||  ||.||. | |   .. |
FVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEY---LHSHMGIIHRDYLKPENILLDEDGHIKLTD
Kinase 89678.m00207.AA AGC 169-208 31 4.2e-05 7.58 In-house 267-307 (395) Show / Hide 
Range on Protein: 169-208
Range on HMM: 267-307/395
Sequence Identity: 31% (14 aa)

G--TIPFAAPEIFSGQRKCESDIFS--FGAIMFNMITECYPFAS
|  |  . ||||.      . |. |  .|..|. |.| . || .
GPCTPEYMAPEIL---YGKACDWWSFGLGCLMYEMLTGYPPFYG
Kinase 89678.m00207.AA CAMK-Unique 83-142 25 5.2e-05 12.25 In-house 112-190 (363) Show / Hide 
Range on Protein: 83-142
Range on HMM: 112-190/363
Sequence Identity: 25% (21 aa)

ILMDYIPGNTLTKLING---------------------GYVSN--RVKRLYMLEIFYAIAYQLTLMRENGIKHRDFKPDNIVV
|.|.|..|..| ..|.                      |. |   .  ...|...  |.||    | ...| ||| |..||.|
IVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAY----MHSQDIVHRDLKLENIMV
Kinase 89678.m00207.AA CAMK-Unique 169-209 30 0.000105 11.24 In-house 237-296 (363) Show / Hide 
Range on Protein: 169-209
Range on HMM: 237-296/363
Sequence Identity: 30% (18 aa)

GTIPFAAP--------------EIFSGQR---KC--ESDIFSFGAIMFNMITECYPFASA
||....||              |.  .|.   .|   ||| | |.||. |.. | ||...
GTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCE
Kinase 89678.m00207.AA CAMKL 127-152 46 0.002202 6.49 In-house 145-172 (297) Show / Hide 
Range on Protein: 127-152
Range on HMM: 145-172/297
Sequence Identity: 46% (13 aa)

ENGIKHRDFKPDNIVVDGDM--IPHIID
..|| ||| ||.|| .| ..     |||
SHGIVHRDIKPENILLDENGNNNIKIID
Kinase 89678.m00207.AA Ciliate-E3 132-143 75 0.237814 0.32 In-house 126-137 (202) Show / Hide 
Range on Protein: 132-143
Range on HMM: 126-137/202
Sequence Identity: 75% (9 aa)

HRDFKPDNIVVD
| | ||||| ||
HSDIKPDNILVD
Kinase 89678.m00207.AA TKL-Unique 288-303 31 0.343974 0.17 In-house 262-277 (290) Show / Hide 
Range on Protein: 288-303
Range on HMM: 262-277/290
Sequence Identity: 31% (5 aa)

NKKISELIELCCKQEP
.| ...||. |....|
PKEYRDLIQQCWHHDP
Kinase 89678.m00207.AA Pkinase 294-373 13 0.937091 3.75 Pfam 202-271 (293) Show / Hide 
Range on Protein: 294-373
Range on HMM: 202-271/293
Sequence Identity: 13% (11 aa)

LIELCCKQEPFSRI-RPEDLQDRIDTLAKETLTANELDQYNKYCEYLFSLEQKEYGTKEMIDKANKLGFYENNETLYSIIK
|.|..|.. ||.    ...  | .  ...   . .. | ........|.  .  . .     . ...  .. .|.. ..||
LYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTF-HNWSEECKDFIK