Gene 84843.m00232 (T.vaginalis)

84843.m00232

Species: T.vaginalis
Alias: 84843.m00232, TvagK0939
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
84843.m00232.AA Protein None 313 None Fasta, JSON
84843.m00232.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of 84843.m00232.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84843.m00232.AA Ciliate-E2 106-258 24 2.3e-28 94.49 In-house 165-365 (365) Show / Hide 
Range on Protein: 106-258
Range on HMM: 165-365/365
Sequence Identity: 24% (52 aa)

IAFCLLHTLRVLHSNN-IIVRNLSVYNIMLSNEQSCPFKIKNFYLAKILDVQ-------IQSHILEYDD---------------------------FPAP
.. |... |. |||.| || |..   ||..        ||  | |.|..| .        |. .. .                             . ||
YIACIILALEYLHSKNNIIHRDIKPENILF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAP

EVLESKP---------YGPPSDIWSLGCILYLLLRGLPPYPFTKKNDATYIKEHPIVFDDD--------------VWSTISEDAREIVQG----MLQLDP
|.|..|.         |.  .||||||.||| .| | ||.          ||. .| |.                 |  .|...  . .     ||| ||
EILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP

QRRST-VDDLLETAWI
. | |  ...|.  |.
EKRITGWEQILNHPWF
Kinase 84843.m00232.AA Ciliate-E2-Unclassified 86-258 23 2.1e-27 92.15 In-house 123-352 (352) Show / Hide 
Range on Protein: 86-258
Range on HMM: 123-352/352
Sequence Identity: 23% (53 aa)

GDLITNLLPNPILSERYIS-----TIAFCLLHTLRVLHSNN-IIVRNLSVYNIMLSNEQS-CPFKIKNFYLAK-----------------ILDVQIQSHI
.||  |.. . |..|. ..     ... ..|  |  ||..| || |..   ||...|...    ||  | ..|                 |.. |.....
NDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTF

LEYDDFP----APEVLESKPYGPP----SDIWSLGCILYLLLRGLPPYPFTKKND---------------ATYIKEH--PIVFDDDVW----STISEDAR
     .     |||||... |. .    .||||||.||| .| | .|.. .....                 | . .  .| |.   |     ..|. | 
CGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAK

EIVQ----GMLQLDPQRRSTVDDLLETAWI
....     ||. .|  | | ...|.  |.
DFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 84843.m00232.AA CAMK 169-258 25 1e-25 79.24 In-house 288-425 (425) Show / Hide 
Range on Protein: 169-258
Range on HMM: 288-425/425
Sequence Identity: 25% (35 aa)

APEVLES--------------KPYGPPSDIWSLGCILYLLLRGLPPY--------------------PFTKKNDATYIKEHPI---VF---DDDVWSTIS
|||||..              ..|||..|.||.|.||| .| | ||.                     | |   . |  ..|    .    ....|. ||
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

ED--------AREIVQGMLQLDPQRRSTVDDLLETAWI
..        ..  ...||| ||..| |... |.  |.
DEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 84843.m00232.AA CAMK-Unique 80-258 21 1.4e-25 81.29 In-house 114-363 (363) Show / Hide 
Range on Protein: 80-258
Range on HMM: 114-363/363
Sequence Identity: 21% (55 aa)

QQIVPAGDLITNLLP--------------------NPILSE--RYISTIAFCLLHTLRVLHSNNIIVRNLSVYNIMLSNE-Q-------------SCPFK
......|||   ..                     . ..||  . ...| .|||  .  .||..|. |.|   |||.... .                 |
MEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIK

IKNFYLAKILDVQIQSHILEYD----DFPAP--------------EVLESKPYGPPS----DIWSLGCILYLLLRGLPPYPFTKKNDA-----------T
. .| |.. ..  . .|..  .    .. ||              ||..  .|. ..    |||||| |.|..| | |  ||.  ...            
LCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCP--PFDCECEDRDYENHDKEIFE

YIKEHPI-VFDDDVWST---ISEDAREIVQGMLQLDPQRRSTVDDLLETAWI
 |. . .  || ..|.    ||. |  .|.. ...||  | .   |||  ||
CICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 84843.m00232.AA CAMK1 169-258 39 4.4e-24 66.85 In-house 181-276 (276) Show / Hide 
Range on Protein: 169-258
Range on HMM: 181-276/276
Sequence Identity: 39% (39 aa)

APEVLES---KPYGPPSDIWSLGCILYLLLRGLPPYPFTKKN-D---ATYIKEHPIVFDDDVWSTISED-AREIVQGMLQLDPQRRSTVDDLLETAWI
||||||    |||. . |.|| |.|.| || | |  ||  .| |      ||. .. |. . |  ||.  | . . .|| .||. | |... |.  ||
APEVLECKKDKPYDKACDMWSIGVITYILLCGYP--PFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 84843.m00232.AA RAD53 169-258 31 8.3e-24 67.34 In-house 194-305 (305) Show / Hide 
Range on Protein: 169-258
Range on HMM: 194-305/305
Sequence Identity: 31% (35 aa)

APEVLESK---------------PYGPPSDIWSLGCILYLLLRGLPPYPFTKKN--DATYIKEHPIV-----FDDDVWSTISEDAREIVQGMLQLDPQRR
||||. ||                |..  |.||.|||||..| | ||  . ..     . ..|  .      |.  .|. ||| |.  ...||..|| .|
APEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKR

STVDDLLETAWI
.|.|..| . |.
YTIDEALNHPWM
Kinase 84843.m00232.AA ULK 114-258 26 2.1e-22 75.1 In-house 143-329 (329) Show / Hide 
Range on Protein: 114-258
Range on HMM: 143-329/329
Sequence Identity: 26% (49 aa)

LRVLHSNNIIVRNLSVYNIMLSNEQ----------SCPFKIKNFYLAKILDVQ-IQSHILEYDD----------FPAPEVLE----SKPYGPP-SDIWSL
.. ||..||| | .   ||...| |          .  .||  | .|| .|    .  .. .            . ||..|.     |||.   .|||||
FKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSL

GCILYLLLRGLPP---YPFTKKNDATYIKE-------------HPIVFDDD-VWSTISEDAREIVQGMLQLDPQRRSTVDDLLETAWI
|||.| .| | ||   . |.. ..  ..|.             .|. |..|    .||.. ... ..||| |.  | . ..|..  |.
GCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 84843.m00232.AA ULK 114-258 26 1.1e-20 70.13 In-house 139-324 (324) Show / Hide 
Range on Protein: 114-258
Range on HMM: 139-324/324
Sequence Identity: 26% (50 aa)

LRVLHSNNIIVRNLSVYNIMLSNEQ----------SCPFKIKNFYLAKILDV-QIQSHILEYDD----------FPAPEVLE----SKPYGPP-SDIWSL
.. ||..||| | .   ||...| |          .  .||  | .||..|  . .  .. .            . ||..|.     |||.   .|||||
FKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSL

GCILYLLLRGLPP---YPFTKKND------------ATYIKEHPIVFD---DDVWSTISEDAREIVQGMLQLDPQRRSTVDDLLETAWI
|||.| .| | .|   . |.. ..             .|||  || |.   .|.   ||.. ... ..||| |.  | . .....  |.
GCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPK--ISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 84843.m00232.AA Pkinase 169-258 31 1.1e-20 74.18 Pfam 179-293 (293) Show / Hide 
Range on Protein: 169-258
Range on HMM: 179-293/293
Sequence Identity: 31% (36 aa)

APEVLE-SKPYGPPSDIWSLGCILYLLLRGLPPYPFT----KKNDATY----IKEHPIVFDDDVWSTIS-----------------EDAREIVQGMLQLD
||||.  ...|||..|.||.||||| .| | ||.|      . .|  .    |.. |. || . |..||                 |...... ..|..|
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

PQRRSTVDDLLETAWI
|..| | ...|.  |.
PKKRPTAEQILQHPWF
Kinase 84843.m00232.AA RSK 169-258 24 2.8e-19 67.39 In-house 176-278 (278) Show / Hide 
Range on Protein: 169-258
Range on HMM: 176-278/278
Sequence Identity: 24% (25 aa)

APEVLE---SKP-YGPPSDIWSLGCILYLLLRGLPPYPF----TKKNDATYIKEHPIVFDDDVWSTISEDAREIVQGMLQLDPQRRST-----VDDLLET
|||.|     .  ..   |.||||...| .| | ||.      ..|   . |..  . .. . |...|..|......||. ||..| .     ...... 
APEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQH

AWI
.|.
PWF
Kinase 84843.m00232.AA STE 169-258 21 1.9e-18 61.81 In-house 230-359 (359) Show / Hide 
Range on Protein: 169-258
Range on HMM: 230-359/359
Sequence Identity: 21% (28 aa)

APEVLES------KPYGPPSDIWSLGCILYLLLRGLPPY---PFTK--KNDATYI-------------KEHPIVFDDDV--------------WSTISED
||||..       |.|.  .||||||| .  .. | ||.   . ..   . .. .             ...|   |.                 .  |..
APEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPE

AREIVQGMLQLDPQRRSTVDDLLE--TAWI
 .. ..  || ||. | |...||.    .|
FKDFINKCLQKDPNKRPTASQLLKSEHPFI
S_TKc 84843.m00232.AA S_TKc 10-258 24 2.9e-15 46.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-258
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

FETLELYDASAFSRTFNAVEAESDRQVSI-LIYYKNFPREQIVSIQPPDIDFIGLTTVYDITEDQDFIVVPQQIVPA--GDLITNLLPNPI------LSE
.| |..    ||.. . ... ...|.| |  |  ... ||  .  .    .   . . ||. .| |.. .    ..   ||| . .  ..       ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

RYISTIAFCLLHTLRVLHSNNIIVRNLSVYNIMLSNEQSCPFKIKNFYLAKILDVQIQSHILEYDDFP------APEVLESKPYGP-PSDIWSLGCILYL
  .  ..  ..  |  .||..|| | |   ||.|..      ||  | ||..|           . |       |||||   .||. ..|.||.||||| 
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLRGLPPYPFTKKNDATYIKEHPIVFDDDVWSTISEDAREIVQGMLQLDPQRRSTVDDLLE-------TAWI
.| | ||.|    .... .|              |..|.......|| ||..| |. ..|.         |.
MLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84843.m00232.AA STE 87-123 26 0.014268 5.05 In-house 126-174 (359) Show / Hide 
Range on Protein: 87-123
Range on HMM: 126-174/359
Sequence Identity: 26% (13 aa)

DLIT-NLLPNPILS----------ERYISTIAFCLLHT-LRVLHSNNII
|.|  .  ..  |.          |  |..|.. .|.  |  |||..||
DIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHII