Gene 83396.m00086 (T.vaginalis)

83396.m00086

Species: T.vaginalis
Alias: 83396.m00086, TvagK0742
External Links:
Annotation:

Classification

Group: Other
Family: CAMKK

Sequence

Name Sequence Type Origin Length Description Download
83396.m00086.AA Protein None 313 None Fasta, JSON
83396.m00086.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of 83396.m00086.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 83396.m00086.AA S_TKc 40-310 25 8.4e-74 252.41 SMART 1-231 (231) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-231/231
Sequence Identity: 25% (73 aa)

YDILQEIGQGAFAKVFLIRNRETDTLYAAKAYSMFQLLQRRLGEEPREARFFSEVKILSTINHKNCLKIIELIKDDVTHKIYLIVPYAGR--GPLSPKCW
|.||..||.|||.||.. |...|. ..| |  .                .. .|..||.  .|.|  |... . |   ...|..  |..   | |     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIK

EANI------MDEKDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDDGNVMLCDFSVSKQLSSSDELVDDTQGTPAFRAPEEQLTDPFDAKKSDVWS
. .       ..| .|. ...|......|.|...|.|||.||.|.|. .  ....||| ...||       .   ||| ..|||     ... .|.|.||
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWS

YGISLYVMIFGHLPYDIDFENDNFVQQDIKLSQQILNTEINLERNPPISQELKSLFQAIFVHDPKKRPSISEVLK-------NDWF
 |. || |. |  |..          |. .. ..|.            |.|.|.. . ... ||.|||.. |.|.         ||
CGCILYEMLCGYPPFP----------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83396.m00086.AA CAMK 45-310 17 7.9e-71 227.24 In-house 1-425 (425) Show / Hide 
Range on Protein: 45-310
Range on HMM: 1-425/425
Sequence Identity: 17% (76 aa)

EIGQGAFAKVFLIRNRETD------------TLYAAKAYSMFQLLQ-----------RRLG---------EEPREARFFSEVKILST-------INHKNC
..|.|.|.||.| ....|             . .|.| ..  .|             ..           ..  ......|..|...       ..|.| 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKIIELIKD-----------DVTH-------KIYLIV---PYAGRGPL----------SPK----------CWEANIMDEKDAKDVFKQLAEGIQYLHNN
.|..| . |             ..       ..|..     |.  | |           ..          . |   ..|..|. .|.|......|.|..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

NIVHRDIKPDNVLIQDD-----------------GNVMLCDFSVSKQLSSS-----------------------DELVDDTQGTPAFRA-PEEQLT----
||||||.||.|.|..|.                 .|. ..||  .... ..                       ...  .  |||.. | ||  .     
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------DPFDAKKSDVWSYGISLYVMIFGHLPYDIDFENDNF-----VQQDIKLSQQILNTEINLE-----------------------RNPPISQE
          | . .|.|.|| |. ||.|  |..|.. | .|. .      . | .| ..|.. . . .                        .  .|||
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQE

LKSLFQAIFVHDPKKRPSISEVLKNDWF
 |.| . . . ||.||..|...|.  |.
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 83396.m00086.AA CAMKL 40-310 26 8.5e-68 215.39 In-house 1-297 (297) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-297/297
Sequence Identity: 26% (81 aa)

YDILQEIGQGAFAKVFLIRN-RETDTLYAAKAYSMFQLL-----------QRRLGEEPREARFFSEVKILSTIN---HKNCLKIIELIKDDVT----HKI
|.|....|.|.|.|| | .. | | . .| | .  . .            | .   | .. | . |..|.. .|   |.|  |. | | .. .     ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKH---ESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKI

YLIVPYAGRGP--LSPKCWEA----NIMDEKDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDDG--NVMLCDFSVSKQLSS----SDELVDDTQGT
||.  |.. |   |  .  .       |.|..|.  |.|. ....|.|...||||||||.|.|. ..|  |. ..||  | .       .... .   |.
YLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGS

PAFRAPEEQLT--DPFDAKKSDVWSYGISLYVMIFGHLPYDIDFENDNF---VQQDIKLSQQILNTEINLERNP-PISQELKSLFQAIFVHDPKKRPSIS
|.. |||  .   .|.|..| |.|| |. ||.|..|.||    |..|.     . .| .   . ..    .. .  .| ....| . . ...|.|||.| 
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLP----FDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIH

EVLKNDWF
....  |.
QIMNHPWM
Kinase 83396.m00086.AA CAMKK 40-310 22 3.5e-65 205.67 In-house 1-396 (396) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-396/396
Sequence Identity: 22% (91 aa)

YDILQEIGQGAFAKVFLIRNRET-DTLYAAKAYS-----MFQLLQRRLGEEP----------REARFF-------SEVKILSTINHKNCLKIIELIKDDV
| ...|||||.|.|| | .|... ...|| | ..     .... ....   |          .|.. .       .|. |.  .||.|  | .| | |  
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

THKIYLI-VPYAGRGPLSPKC-WEA------------------------NIMDEKD---------------------AKDVFKQLAEGIQYLH-NNN---
  |||..   |. ||..  .  |.                          ||.|.                      |. .| . . |..||| ...   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------IVHRDIKPDNVLIQDDG---NVMLCDFSVSKQLSSSDELVDD-----------TQGTPAFRAPEEQLT-DP-------------
                |.||||||.| || ..|   .| ..||.||......|.....           |.|||||.||| . . .              
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-FDAKKSDVWSYGISLYVMIFGHLPYDIDFENDNFVQQDIKLSQ---QILNTEINLER-----------NPPISQELKSLFQAIFVHDPKKRPSISEVLK
 .. |. |.|. |..|| ..|| .|.        . . ...|     .|.| .|  ..           .| || .||.|..     .|.|| .|.....
IYCGKAADIWALGVTLYCFVFGKCPF--------WHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKV

NDWF
..|.
HPWV
Kinase 83396.m00086.AA Ciliate-E2 40-310 20 1.3e-62 213.79 In-house 1-365 (365) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-365/365
Sequence Identity: 20% (81 aa)

YDILQEIGQGAFAKVFLIRNRETDTLY------------------AAKAYSMFQLLQRRLGEEPREARFFSEVK----------ILSTINHKNCLKIIEL
|.... ||||.|..|.. ...... ..                  ..| | | .. .. . .  .| . . |..          ||...||.| .|..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IKDDVTHKIYLIVPYAGRGPLSP---KCW---------EANIMDEKDAKDVFKQLAE---------------GIQYLHNNN-IVHRDIKPDNVLIQDDGN
 ..  ...|||.  |.  | |     ...         . . ..|| .|...||...               ...|||..| |.||||||.|.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VMLCDFSVSKQLSSS-------------------------------DELVDDTQGTPAFRAPEEQLTDPFDA--------KKSDVWSYGISLYVMIFGHL
. ..||  ||... .                               ..... . ||| . |||     . |         .|.|.|| |. || |.|| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYDIDFENDNFVQQDIKLSQQILNTEINLERN----------------PPISQELKSLFQA----IFVHDPKKRPS-ISEVLKNDWF
|.                 |||.. .|..  .                  .||| | |..     ... ||.||.. ....|.. ||
PF----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Pkinase 83396.m00086.AA Pkinase 40-310 24 4.9e-62 217.22 Pfam 1-293 (293) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

YDILQEIGQGAFAKVFLIRNRETDTLYAAKAYSMFQLLQRRLGEEPREARFFSEVKILSTINHKNCLKIIELIKDDVTHKIYLIVPYAGRG----PLS--
| |.. ||.|.|..|.. ... |  ..| |  .    ....  ......|  ||..|.  .||.| .....   |    .||.. .|.. |     |.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK----KRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDY

--PKCWEANIM--DEKDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDDGNV----MLCDFSVSKQL-SSSDELVDDTQGTPAFRAPEEQLTDPFDA
     |. . .  .|...|....|...|..|.|...|.|||.||.|.|| ..|..     .||| ..||.   ...  ..  ||| ..|||  .... . 
IST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

KKSDVWSYGISLYVMIFGHLPYDIDFENDNFVQQDIKLSQQILNTEINLERNPPIS-------------------QELKSLFQAIFVHDPKKRPSISEVL
.|.|.||.|. || |..|..|.. .  ..     .... ..|. ...  ..  ..|                   .|.|..   ..  ||||||.. ..|
PKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

KNDWF
. .||
QHPWF
Kinase 83396.m00086.AA Ciliate-E2-Unclassified 40-310 24 5.3e-56 192.36 In-house 1-352 (352) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-352/352
Sequence Identity: 24% (86 aa)

YDILQEIGQGAFAKVFLIRNRETDTLY-----AAKAYSMFQLLQRR-LGEEPREARFFSEVK-------------ILSTINHKNCLKIIELIKDDVTHKI
| |.. ||||.|.||.. ...... .|     . |. .  |.....   |. .|.    . |             ||. ..| . .| ..  .|  . .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQD--KQNI

YLIVPYAGRGPLSP---KCWE--------------ANIMDEKDAK-----DVFKQLAEGIQYLHNNN-IVHRDIKPDNVLIQDDG---NVMLCDFSVSKQ
|..  |.  | |.    |..                .| .|. ||     . |.|. .|..||| .| |.||||||.|.|....|   .. ..||. ||.
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

LSSS---------------DELVDDTQGTPAFR---APEEQLTD-PFDA---KKSDVWSYGISLYVMIFGHLPY-DIDFENDNFVQQ-------DIKLSQ
. ..               ... ... ||| .    .. | |     |    .|.|.|| |. || |.|| .|. | . | ......       .  | |
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

QILNTEINLERNPP------ISQELK----SLFQAIFVHDPKKRPSISEVLKNDWF
.|.. .|.    |.      .|.| |     |.| ... .|.||......|.  ||
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 83396.m00086.AA CAMKK-Unclassified 142-310 26 1.7e-49 159.23 In-house 175-392 (392) Show / Hide 
Range on Protein: 142-310
Range on HMM: 175-392/392
Sequence Identity: 26% (59 aa)

MDEKDAKDVFKQLAEGIQYLHNNN---------------------IVHRDIKPDNVLIQDDGN-----VMLCDFSVSKQLSSSDEL-VDDTQGTPAFRAP
|.|  .|  | | . |.||.||.|                     |.||||||.| || ...|     . ..||..|. ......  . ...||..|.||
MHEQYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAP

EEQLTDPFDAKKSD---------------------------VWSYGISLYVMIFGHLPYDIDFENDNFVQQDIKLSQ-QILNTEINLER--NPPISQELK
| .    | .. .|                           .|| |...| |... ||.        . . ...|   .|.. |||.     | .| |.|
EFWSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPF--------WHKNLQELFHQMICQKEINFPPQYHPHCSHEFK

SLFQAIFVHDPKKRPSISEVLKNDWF
.|.|     .|||| .|. .|...||
DLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 83396.m00086.AA ULK 40-310 25 1.1e-48 168.09 In-house 1-329 (329) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-329/329
Sequence Identity: 25% (84 aa)

YDILQEIGQGAFAKVFLIRNRETDTLYAAKAYSMFQLLQRRLGEEPREAR-------FFSEVKILSTIN----HKN----CLKIIELIKDDVTH-KIYLI
| . ...|.|.|.||.  || .|.. |.....   ....  . ... |.        . .|.||. ...    |||    . | ..  ... .|  ||.|
YCLNHCLGKGSFGKVYKGRNKKTKD-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETS-NHNNIYII

VPYAGRGPLS------PKCWEAN----IMDEKDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDD------------GNVMLCDFSVSKQLSSS---
. |   | |.       |. |      .  |. |. .|||...| ..|| .||.||||||.|.|| ..            | . ..||  .|.....   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

DELVDDTQ------GTPAFRAPE--EQL--TDPFDAKKSDVWSYGISLYVMIFGHLPYDIDFENDNFVQQDIKLSQQ-------ILNTEINLE---RNPP
...   .       ||| . ||.  ...    |.. .|.|.|| |. .| |..|  |.     || . |. .|| ..       | .. .. .    .|.
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

ISQELKSLFQAIFVHDPKKRPSISEVLKNDWF
||.|.|.|..  .. |.|.| |. |.... ||
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 83396.m00086.AA CAMK-Unique 40-310 20 3.4e-44 143.69 In-house 1-363 (363) Show / Hide 
Range on Protein: 40-310
Range on HMM: 1-363/363
Sequence Identity: 20% (75 aa)

YDILQEIGQGAFAKVFLIRNRETDTLYAAKAYSM-----FQLLQ-------RRLGEEPREARFFSEVKILSTINHKNCLKIIEL---IKDDVTH------
|. .. ||.|.| .|.   .||| ...| |           ..|       ..  |  |.  .  |. |. . .| | .|. .    |. | .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------KIYLIVPYAGRGPLSPKCWE--------------------ANIMDE--KDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDDGN-----
        ..|..  |.  | |. .. .                      .. |   |.  .. .|.. . |.|...|||||.|..|....  ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------VMLCDFSVSKQLSSSDEL--VDDTQGTPAFRAP-------------EEQLT-DPFDAKKS---DVWSYGISLYVMIFGHLPYDIDFEND
           . ||||  ....... .      . ||| . ||             .| .  .. | . |   | || |  .| |..| .| | ..|..
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

NFVQQDIKLSQQILNTEI-NLERNP---P--ISQELKSLFQAIFVHDPKKRPSISEVLKNDWF
     | .. . |.  .. |...     |  ||||.|.. .  .. ||..| |..| |...|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 83396.m00086.AA ULK 144-310 28 3.5e-39 136.48 In-house 125-324 (324) Show / Hide 
Range on Protein: 144-310
Range on HMM: 125-324/324
Sequence Identity: 28% (58 aa)

EKDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDDGNVM------------LCDFSVSKQLSSSDELVDDTQ---------GTPAFRAPE--EQL--
|. |. .|||...| ..||..||.||||||.| || ..                ..||  .|.. . ..  ...|         ||| . ||.  ...  
EQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGE

TDPFDAKKSDVWSYGISLYVMIFGHLPYDIDFENDNFVQQDIKLSQQ-------ILNTEINLE---RNPPISQELKSLFQAIFVHDPKKRPSISEVLKND
  |.. .|.|.|| |. .| |..|  |.  .  || . .  .|| ..       | |. |.      .|.||.|.|.|..  .. |.|.| |. |.... 
QKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHP

WF
||
WF
Kinase 83396.m00086.AA MARK 40-189 35 1.1e-36 117.53 In-house 1-150 (262) Show / Hide 
Range on Protein: 40-189
Range on HMM: 1-150/262
Sequence Identity: 35% (55 aa)

YDILQEIGQGAFAKVFLIRNRETDTLYAAKAYSMFQLLQRRLGEEPRE-ARFFSEVKILSTINHKNCLKIIELIK-DDVTHKIYLIVPYAGRGPLSPKCW
| .|..||.|..||| | ... |.. .| | |  |.|       .| .   ...|..|.. ..|.|. |  . |  |. .|.||||  ||..|.|   . 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLN------DPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELY-DYI

EAN---IMDEKDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDDG--NVMLCDF
.|     . |..|.  |.|. ....|.|..|||||||||.|.|| ..|  |. ..||
KAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDF
Kinase 83396.m00086.AA MARK 207-310 33 4.5e-20 62.46 In-house 167-262 (262) Show / Hide 
Range on Protein: 207-310
Range on HMM: 167-262/262
Sequence Identity: 33% (35 aa)

GTPAFRAPEEQLTDPFDAKKSDVWSYGISLYVMIFGHLPYDIDFENDNFVQQDIKLSQQILNTEINLERNPPISQELKSLFQAIFVHDPKKRPSISEVLK
|||.. |||  |  | |..| |.|| |. ||.|. |..|.|      .  | . .| ..||. .     .  .| |...| | .....|..||.|.|..|
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD------GDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMK

NDWF
  |.
HPWM
Kinase 83396.m00086.AA TyrKc 40-309 18 8.4e-15 16.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

YDILQEIGQGAFAKVFLIRNRETDTLYAAKAYSMFQLLQRRLGEEPREARFFSEVKILSTI--NHKNCLKIIELIKDD-----VTHKIYLIVPYAGRGPL
   ....| ||| .|.. . .   .  | |                 .. | .| .|.. .  .|.| ....  . ..       . ..... |.  | |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

S---PKCWEANIMDEKDAKDVFKQLAEGIQYLHNNNIVHRDIKPDNVLIQDDGNVMLCDFSVSKQLSSS-------DELVDDT--QGT---PAFRAPEEQ
     |. .      ||  .   | |.| .||| .|..|||.   |.|. ... |  .||  |. . .        |  .  .  .|    |    . | 
KDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LTDPFDA---KKSDVWSYGISLY-VMIFGHLPYDIDFENDNFVQQDIKLSQQILNTEINLERNPP--------ISQELKSLFQAIFVHDPKKRPSISEVL
.   ..     ||||||.|. .. .. .|  ||  . ..   .  .. . ... . .  ... |          ..|. .. .    .||..||. ||. 
I---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYR-MPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-

KNDW
. ..
HECF
Kinase 83396.m00086.AA ULK 40-124 21 8.8e-12 38.14 In-house 1-96 (324) Show / Hide 
Range on Protein: 40-124
Range on HMM: 1-96/324
Sequence Identity: 21% (21 aa)

YDILQEIGQGAFA-KVFLIRNRET---DTLYAAKAYSMFQLLQRRL---GEEPREARFFSEVKILSTIN---HKN--CLKIIELIKDDVTH-KIYLIV
| . ...|.|.|. ||.  || .|   . ..|.|  ..... .  .   | .     . .|..|. ...   |.|  . | ..  ... .|  ||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEG-QYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETS-NHNNIYIIM
Kinase 83396.m00086.AA CAMKK-Unclassified 40-130 24 8e-08 21.23 In-house 1-107 (392) Show / Hide 
Range on Protein: 40-130
Range on HMM: 1-107/392
Sequence Identity: 24% (26 aa)

YDILQEIGQGAFAKVFLIRNRETD----TLYAAKAYSMFQLLQRRLGEEPRE---ARFF-------SEVKILSTINHKNCLKIIELIKDDVTHKIYL--I
| .|...|.|.|.|| |  .| |.    . . |. ..  |.| ...     .    . .       .|. |   ..| |  |  | | |    |||.  .
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDKIYMGQV

VPYAGRG
  |. .|
MEYCQMG
Kinase 83396.m00086.AA Pkinase_Tyr 153-207 30 2e-06 22.12 Pfam 119-174 (270) Show / Hide 
Range on Protein: 153-207
Range on HMM: 119-174/270
Sequence Identity: 30% (17 aa)

QLAEGIQYLHNNNIVHRDIKPDNVLIQDDGNVMLCDFSVSKQLSSSDEL-VDDTQG
| |.| .||...|..|||.   |.|. ... |  |||  .. . . |.  .  . |
QIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG
Kinase 83396.m00086.AA Pkinase_Tyr 226-237 58 0.0679 7.04 Pfam 194-205 (270) Show / Hide 
Range on Protein: 226-237
Range on HMM: 194-205/270
Sequence Identity: 58% (7 aa)

KSDVWSYGISLY
||||||.|. ..
KSDVWSFGVLMW
Kinase 83396.m00086.AA Pkinase_Tyr 40-56 29 0.25739 5.08 Pfam 1-17 (270) Show / Hide 
Range on Protein: 40-56
Range on HMM: 1-17/270
Sequence Identity: 29% (5 aa)

YDILQEIGQGAFAKVFL
  .....|.||| .|..
ITFGKKLGEGAFGEVYK