Gene 81909.m00079 (T.vaginalis)

81909.m00079

Species: T.vaginalis
Alias: 81909.m00079, TvagK0677
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81909.m00079.AA Protein None 1609 None Fasta, JSON
81909.m00079.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 81909.m00079.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81909.m00079.AA NEK 4-258 49 1.9e-159 536.0 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-286/286
Sequence Identity: 49% (142 aa)

YDQVKVLGQGGFGKAILGKRKKDGYM-----VCIKEVRLTALSQKDREEAM-KEIKVLAALNHPYIVKYIENFQERG--SLYIVMEFAD-GGDLAQK---
|. .|..||| |||. . .||.|| .     ...|.. .. .|.|....|. .|...|. |.||.||||.. |.|..  .|.||||... ||||.||   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IEKK--GRKPFSEEEVMKNFIQIALAIKYCHDR-----KILHRDLKGQNVFLMKDGT----VKLGDFGIARVLEHTFQVCKT-QIGTPFYLSPEICQGKP
|.|.   .|.|.||.... |||..||.||.|||     ||||||.| ||.|| |...    ||.|||||..||.|| .  .| |.||| |.|||.||.||
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNSKTDIWSLGCILYELCTL--KHAFEAA--NMNALLMNIIRG-KYTPIPAQ--YSQDLRNLVDAMLTKEPEKRPNINQILTLPFI
||.| |||||||.|||.|||  ||.|||   ||..| |.|..| .| ||| .  |||||.||.  ||.|.||.||..|||| .|||
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 81909.m00079.AA NEK1 4-258 53 6.4e-146 491.07 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-276/276
Sequence Identity: 53% (148 aa)

YDQVKVLGQGGFGKAILGKRKKDGYMVCIKEVRLTALSQKDREEAMKEIKVLAALNHPYIVKYIENFQERGS--LYIVMEFADGGDLAQKIEKK--GRKP
|.  |..|.| ||||.| |.| || . .||| ...  ..|.|||.|.| ..|| . || |||| | |.|.|.  ||||||..|||||.|||...    |.
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FSEEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLM--KDG---------------TVKLGDFGIARVLEHTFQVCKTQIGTPFYLSPEICQGKPYNS
||| . |  |.|| || .. |||||||||.| ||.||   |.|               .||||||||||.| ||    .| |||| |||||||| |||| 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KTDIWSLGCILYELCTLKHAFEAANMNALLMNIIRGKYTPIPAQYSQDLRNLVDAMLTKEPEKRPNINQILTLPFI
|.|||||||.|||||||||.|||.|. .| . |..| |.|||. ||..|..||  |. . |. || .||||. |||
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 81909.m00079.AA NEK8 4-258 41 1.2e-136 392.73 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-278/278
Sequence Identity: 41% (114 aa)

YDQVKVLGQGGFGKAILGKRKKDG--YMVCIKEVRLTALSQKDREEAMKEIKVLAALNHPYIVKYIENFQERGSLYIVMEFADGGDLAQKIEKKGRKPFS
|  . |.|.| || ..|  || |.    | .|.. .. .| | |  |. || ||. |.|| |. |...| | ..| |.|| |||| |.|.| .   | |.
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFE

EEE-----------------VMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKD-GTVKLGDFGIARVLEHTFQVC--KTQIGTPFYLSPEICQGKPYN
||.                 .   |.|. .|. . |.  ||||||| ||.|. .. . ||.|||||. ..         || .||| |.|||.|.|||||
EERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYN

SKTDIWSLGCILYELCTLKHAFEAANMNALLMNIIRG-KYTPIPAQYSQDLRNLVDAMLTKEPEKRPNINQILTLPFI
 | |.|.|||.|||.|.|| ||||.|  || . |... .|.||. .|| ..| || . | ..||.||   ||.  | .
QKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase 81909.m00079.AA NEK4 4-258 46 3.8e-107 362.27 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-257/257
Sequence Identity: 46% (119 aa)

YDQVKVLGQGGFGKAILGKRKKDGYMVCIKEVRLTALSQKDREEAMKEIKVLAALNHPYIVKYIENFQERGS--LYIVMEFADGGDLAQKIEKKGRKPFS
|. .|| |.| .|   | . ..|.    .| . |   |...| .| .|...|  | || ||.| | ..      ||||| | .|||| .|  ..  .  .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

EEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKDGTVKLGDFGIARVLEHTFQVCKTQIGTPFYLSPEICQGKPYNSKTDIWSLGCILYELCTLKH
|. |.  |.|||.|  | |...||||||| ||.|| |   .|.|||||.|||.   .. || ||||.|.|||.   .||. | ||||||| .||. ||||
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH

AFEAANMNALLMNIIRGKYTPIPAQYSQDLRNLVDAMLTKEPEKRPNINQILTLPFI
||.| .|| |.  || |.  |.| .||||| |||  || | |.||| | .|.  |.|
AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 81909.m00079.AA S_TKc 4-258 33 2.8e-95 323.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

YDQVKVLGQGGFGKAILGKRKKDGYMVCIKEVRLTALSQKDREEAMKEIKVLAALNHPYIVKYIENFQERGSLYIVMEFADG--GDLAQKIEKKGR----
|. ....|.|.|||  ... ||.|  | ||...         | ...||..|   .||.|||... ||. ..||.|||..||  ||| . |.|.||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

KPFSEEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKDGTVKLGDFGIARVLEHTFQVCKTQIGTPFYLSPEICQGKPYNS-KTDIWSLGCILYEL
.||.| .. . . ||..|..|||...|.||||| .|..| .  ..|..|||.||.|       .|..|||.|..||..   .|.  | |.||.||||||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

CTLKHAFEAANMNALLMNIIRGKYTPIPAQYSQDLRNLVDAMLTKEPEKRPNINQILT-------LPFI
.. .  |.     ......|.          |........ .|.|.||||| . ..|.        |..
LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81909.m00079.AA Pkinase 4-258 27 1.6e-84 291.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

YDQVKVLGQGGFGKAILGKRKKDGYMVCIKEVRLTALSQKDREEAMK--EIKVLAALNHPYIVKYIENFQERGSLYIVMEFADGG----DLAQKIEKKGR
|  ....|.|.||.  ....|..| .|..|....   . . .... .  ||.... ||||.||.... |......|.|||...||    ||.  |. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KPF--SEEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKDGTV----KLGDFGIARVL-EHTFQVCKTQIGTPFYLSPEICQ-GKPYNSKTDIWSL
..|  ||.|. . . ||. ...|||...|.||||| .|... ..|..    |..|||.|... .   . ..|  |||.|..||... |..| .| |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCILYELCTLKHAFEAA------NMNALLMNIIRGKYTPIPAQYS--------------------QDLRNLVDAMLTKEPEKRPNINQILTLPFI
||||||... .  |  .      ...... .| ....     . .                    .... ... .|.| |.|||.. |||  |..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81909.m00079.AA NEK-Unclassified 4-258 37 1.1e-83 276.95 In-house 1-258 (258) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-258/258
Sequence Identity: 37% (98 aa)

YDQVKVLGQGGFGKAILGKRKKDGYMVCIKEVRLTALSQKDREEAMKEIKVLAALNHPYIVKYIENFQERGSLYIVMEFADGGDLAQKIEKKGRK--PFS
||..  ||||| |   | .       .  . .       | .      | .|. | || || | . | |   |.   .. |||.| ..| |.  |  || 
YDKITTLGQGGGGAVYLVR-----HQISKRHLVQQISKRKKKKKRQNKIIILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFD

EEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKDGTVKLGDFGIARVLEHTFQVCKTQIGTPFYLSPEICQGKPYNSKTDIWSLGCILYELCTLKH
|  .|. .||.  |. | | |||.||||| ||.|| .| || .|||||.|...||    .| .||. ..|||.|| .||| . |.||||||.||.||   
EGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEP

AFEAANMNALLMNIIRGKY------TPIPAQYSQDLRNLVDAMLTKEPEKRPNINQILTLPFI
.| . ||  ..| | ..         |.   || || ...  || .....||    |. ...|
FFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase 81909.m00079.AA CAMK 9-258 22 6.5e-79 253.77 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-258
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)

VLGQGGFGKAILGKRKKDG------------YMVCIKEVRLTALS--------------------------QKDREEAMKEIKVLAA-------LNHPYI
.||.|.|||  |...|...              | || .  . |.                          .|||.. ..||...         |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYIENFQERGS-------------------LYIVM---EFADGG----DLAQKIEKKGR-------------KPFSEEEVMKNFIQIALAIKYCHDRKI
.| .| .. .                     .|.||   |...||    || ..| ..|.             . |.|.|. . | ||. |..|||...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKGQNVFLMKD-----------------GTVKLGDFGIARVLEH-----------------------TFQVCKTQIGTPFYLS-PEICQG------
 |||||  |. | ..                 ...|. ||| |.....                       . | .||. ||| | . ||. .|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KPYNSKTDIWSLGCILYELCTLKHAFEAA-------------NMNALLMNIIRGKYTPIPAQ-----------------------YSQDLRN
        ..|. |.|.||.|.||| . . .  |..              |.. |. .|..|||. .| .                        ||. ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVDAMLTKEPEKRPNINQILTLPFI
|.  ||...||||..| |.|  |..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81909.m00079.AA NEK2 4-258 32 3.2e-75 252.71 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-319/319
Sequence Identity: 32% (104 aa)

YDQVKVLGQGGFGKAILGKRKKDGYMVCIKEVRLTALSQKDREEAMKEIKVLAALNHPYIVKYIENF--QERGSLYIVMEFADGGDLAQKIEK--KGRKP
|.  ...|.| ||.    .|| ||     ||     .  | .     |. .|  | ||.||.|       .  .||||||.  ||||.| | |  | |. 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

FSEEEVMKNFIQIALAIKYCHD---------------------RKILHRDLKGQNVFLMKDGT-------------------------------------
. || . . . |. .| . ||                      . |||||.|  |.||  |.                                      
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VKLGDFGIARVLEHTFQVCKTQIGTPFYLSPEICQGKPYNSKTDIWSLGCILYELCTLKHAFEAANMNALLMNIIRGKYTPIPAQYSQDLRNLVDAML
  ||||||| ||.|.|  .  .| .|||.| |||  .| .|| | ||||.||..||.|.|.  |.| |  .|   |  |.. .||.|||..|  ..  |.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

TKEPEKRPNINQILTLPFI
   ...||.|. ||  |.|
NVDHYHRPSIEEILQHPQI
Kinase 81909.m00079.AA STE 4-258 24 5.4e-74 252.14 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-359/359
Sequence Identity: 24% (90 aa)

YDQVKVLGQGGFGKAILGKRKK---------------DGYMVCIKEVRLTALSQ---------------KDREEAMKEIKVLAALN--HPYIVKYIENFQ
.. ....|.|.||.  .....|                | .. ||...|   ..               ..... .||||..  .|  ||.||||.  . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-------ERGSLYIVMEFADGGDLAQKIE---KKGR---------KPFSEEEVMKNFIQIALA-IKYCHDRKILHRDLKGQNVFLMKDGTVKLGDFGIAR
       ....|.|.||. ||| | . |.   ..|.         ..|.|... .   ||  .  .| |. .| |||.|..|..|     ||| |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

VLEH---------------TFQ-VCKTQIGTPFYLSPEICQG------KPYNSKTDIWSLGCILYELCTLKHAFEA-ANMNALLMNIIR-----------
 |..               | |  ..| .||| . .||. |.      |.|. | ||||||| . |..| |. .    .| |..| ..            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GKYTPIP-------------------AQYSQDLRNLVDAMLTKEPEKRPNINQILT--LPFI
   |.  |.|                    ..|..... ..  |.|.|.|||. .| |    |||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81909.m00079.AA Ciliate-E2 4-258 24 1.2e-72 247.63 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YDQVKVLGQGGFGKAILGKRKKDGYM-----------------------VCIKEVRLTALSQKDREEA-MKEIK----------VLAALNHPYIVKYIEN
|. .|..|||.||.  ..|..|....                       . .| ..   . |. .|.  |.||.          .|  ||||.|.|..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--ERGSLYIVMEFADGGDLAQKIEKK----------GRKPFSEEEVMKNFIQIAL---------------AIKYCHDRK-ILHRDLKGQNVFLMKDGT
||   . ..|.|||...|||| . |...          . |.|.|.|. . . ||.                |..|.| .. |.|||.| .|...     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLGDFGIAR----------------VLEHTF----------------QVCKTQIGTPFYLSPEICQGKP---------YNSKTDIWSLGCILYELCTLK
.|. |||...                 .   .                .. .|..||| |..||| .||.         |. | ||||||.||||... |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

HAFEAANMNALLMNIIRGKYTPIP------------------AQYSQDLRNLVDA----MLTKEPEKRPN-INQILTLPFI
. |         ...|  .   .|                   . ||.  .|       || |.||||.. ..|||  |..
PPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81909.m00079.AA ULK 4-258 28 1.6e-70 240.63 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-324/324
Sequence Identity: 28% (93 aa)

YDQVKVLGQGGFG-KAILGKRKKD---GYMVCIKEVRLTALSQKDRE--------EAMKEIKVLAALN---HPY--IVKYIENFQERGS--LYIVMEFAD
|   ..||.| || |   |. ||.   .  | .| . .  ...|  |          ..||...  |.   ||.  |||... |..  .  .||.||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLAQKIEKKGRKP-------FSEEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKD------------GTVKLGDFGIARVLEHT---FQVCKT
|||| | |.|....|       .||.|. . |.||. . |. |...| |||.| ||  . ..            |..|..||| |....      |.|.|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QI------GTPFYLSPEICQ----GKPYN-SKTDIWSLGCILYELCTLKHAFEAANMNALL---MNIIRGK--------YTPIPAQ-------YSQDLRN
.       ||| | .|.| |    .|||. .|.||||||||.||. . |  |..   | .    .. |. .        ..||. .        |.....
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LVDAMLTKEPEKRPNINQILTLPFI
|   ||......| .. .|.  |..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81909.m00079.AA Pkinase_Tyr 4-199 27 6.4e-28 95.18 Pfam 1-210 (270) Show / Hide 
Range on Protein: 4-199
Range on HMM: 1-210/270
Sequence Identity: 27% (58 aa)

YDQVKVLGQGGFGKAILGKRK----KDGYMVCIKEVRLTALSQKD--REEAMKEIKVLAAL-NHPYIVKYIENFQ-ERGS--LYIVMEFADGGDLAQKIE
    |.||.| ||.  .|. |    .... | .| .     ....  ||. |.|.|..  | .|| ||...     ....  .|||||.. .|||     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KK--GRKPFSEEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKDGTVKLGDFGIARVL----EHTFQVCKTQIGTPFYLSPE-ICQGKPYNSKTDI
|.  ...|.. ..  .  .||| .  | ..... ||||   |. . ....|| .||| || .    .  ... .      . ..|| |  || ...|.|.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK-FTTKSDV

WSLGCILYELCTL
|| |  ..|..|.
WSFGVLMWEIFTY
Kinase 81909.m00079.AA TyrKc 4-258 22 8.2e-23 83.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YDQVKVLGQGGFGKAILGKRKKDGYMVCIKEVRLTALSQKDREEAMKEIKVLAAL--NHPYIVKYIENFQER-------GSLYIVMEFADGGDLAQKIEK
    |.|| | ||.  .|. |   ..| .| ..  |     ||. |.|....  |  .|| ||. .    .        . |.||||....||| . . |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KGRKPFSEEEVMKNFIQIALAIKYCHDRKILHRDLKGQNVFLMKDGTVKLGDFGIARVLEHT--------FQVCKTQIGTP-----FYLSPEICQGKPYN
...| .. ..  .  .|||    | |.... ||||   |. . ...||| .||| .| ...           . |.  |.        ..||  . . ..
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

SKTDIWSLGCILYELCTLKHAFEAA------NMNALLMNIIRGKYTPIPAQ--------YSQDLRNLVDAMLTKEPEKRPNINQILTLPFI
.|.|.|| |  ..|..|.             .   .. .. .|.. |.|.          .... ..       .||.||. ..|    ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF