Gene 87054.m00118 (T.vaginalis)

87054.m00118

Species: T.vaginalis
Alias: 87054.m00118, TvagK0059
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87054.m00118.AA Protein None 402 None Fasta, JSON
87054.m00118.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 87054.m00118.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87054.m00118.AA CAMK 16-264 21 1.4e-84 272.32 In-house 1-425 (425) Show / Hide 
Range on Protein: 16-264
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

SIGKGASSEVFYAKHKILG------------LPVAIKGYPKTTMT-------------------------TSNQRQIFEHEAEILRS-------IENPYI
 .|.|. ..|. ..||  .              |||| ..|. ..                         . . |. ...| ||...       .  | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

SALYDVFSD-------------------ENNYYAVI---DLAENG----SFESFI--NPT-------------KPVTENHAKRYFAQLISALSYLHSVHH
  ||.|. |                   ....| |    .....|       ..|  ..              . .||  |.||| |..||. |.|| . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

ILHRDIKADNILLDRY-----------------FNIKIVDFGVSTYYDPNKPTKLP-----------------------PVGSPAYMA-PEVILH-----
| |||.| .|||||                   .||||.||| ....||..  .                         ..|.|.||| |||..      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------DVVTEKSDIWSAGVFLYFITAGIRPFDAE-------------DIPEICSNIVHGAVTFPSY------------------------LSPDLR
         . ...|.|.||.|| ||.   |  ||...             ...|.. .|  |  .||..                        .|.. .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLSKILVKDPKSRWSLEQIAEHPWL
||..|.|..||. |...||. .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 87054.m00118.AA S_TKc 11-264 32 2.1e-78 267.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YEICYSIGKGASSEVFYAKHKILGLPVAIKGYPKTTMTTSNQRQIFEHEAEILRSIENPYISALYDVFSDENNYYAVIDLAEN--GSFESFINPTKP---
|||   ||||| ..|. ..||  |  ||||  .          . .. | .||..   |.|  ||||| | ...| | .....  |.  ..|   ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VTENHAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFNIKIVDFGVSTYYDPNKPTKLPPVGSPAYMAPEVILHDVVTE-KSDIWSAGVFLY
    .| ||..|..|...|| |.||  .|.|||.| .|||||.  .||| |||... .          .|.| ||||||.     .  |.|.|| |. ||
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

FITAGIRPFDAEDIPEICSNIVHGAVTFPSYLSPDLRDLLSKILVKDPKSRWSLEQIAE-------HPWL
   .|  ||.  .. ..  .|.          ||...|...|.|.|||. |..  .. .       |||.
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87054.m00118.AA CAMKL 11-264 31 1.1e-77 247.47 In-house 1-297 (297) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-297/297
Sequence Identity: 31% (93 aa)

YEICYSIGKGASSEVFYAKHKIL-GLPVAIKGYPKTTMT-TSNQRQIFEH-----------EAEILRSIE---NPYISALYDVFSDENN------YYAVI
|.|.  .|||. ..|  |.|... |  |||| . |  ..   . .. .             |..|....     | |  ||.|. ....      .| | 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DLAENGS--FESFI--NPT--KPVTENHAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYF--NIKIVDFGVSTYYDP--NKPTKL--PPVGSPAY
 ....|.     .|  ..   .. .|. |.||| |..||..|.|| . | |||||..|||||     ||||.||| |..|.|  ..| ..     |||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEVILH--D-VVTEKSDIWSAGVFLYFITAGIRPFDAEDIP---------EICSNIVHGAVTFPSYLSPDLRDLLSKILVKDPKSRWSLEQIAEHPWL
||||...   .     | ||||.|| ||..  |  |||.....         .   ..  .  . ....| |.|||..|.|...|. | ...|| .|||.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 87054.m00118.AA AGC 11-264 21 1.3e-77 199.41 In-house 1-395 (395) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-395/395
Sequence Identity: 21% (86 aa)

YEICYSIGKGASSEVFYAKHK------ILGLPVAIKGYPKTT--------MTTSNQRQI-------FEHEAEILRSIE----------NPYISA-LYDVF
.|.   ||||. ..|. ...|        |   |.|   | .        |   ...         .  | .||  .           .|.|   |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

SDENN--YYAVIDLAE--------NGSFESFINPTK-----PVTENHAKRYFAQ-------LISALSYLHSVHHILHRD-IKADNILLDRYFNIKIVDFG
 |...   | | ....         | .|.|.   .       .|..|. |.|.       ...|| |||| ..| ||| .| .|||||.  .||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

VSTY--------------------------------------YDPNK------------PTKLPPVG--SPAYMAPEVILHDVVTEKSDIWS--AGVFLY
 ..                                        . |.             .    .|  .| |||||..     .   |.||   |...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

FITAGIRPFDAE----------DIPEICSNIV------HGAVTFP----------SYLSPDLRDLLSKILVKDPKSRWS----------LEQIAEHPWL
   .|. || ..          .  |.  .|       .  |.||          ...||...||..| |.|||. |             |.| .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 87054.m00118.AA MARK 11-264 35 2.7e-75 245.62 In-house 1-262 (262) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-262/262
Sequence Identity: 35% (93 aa)

YEICYSIGKGASSEVFYAKHKILGLPVAIKGYPKTTMTTSNQRQIFEHEAEILRSIENPYISALYDVFS--DENN-YYAVIDLAENGSFESFINPT--KP
|..   ||.|. ..|  | ||  |  |||| |.|. ..  .... .. |.||..... |.|  |..|.   .|..  | . ..|..|.  ..|      .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

VTENHAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYF--NIKIVDFGVSTYYDPNKPTKLPPVGSPAYMAPEVILHDVVT-EKSDIWSAGVFLYF
 .|. |.|.| |..||..|.|| . | |||||..|||.|     |||| ||| |.   |..  .    |.|.|||||..|    .  | |||| || |||
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNT-FCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

ITAGIRPFDAED--IPEICSNIVHGAVTFPSYLSPDLRDLLSKILVKDPKSRWSLEQIAEHPWL
.. |  |||. .  . |.  .|..|  ..|...|...|.|....|. .|. | ..|.| .|||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 87054.m00118.AA Pkinase 11-264 29 4e-69 240.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

YEICYSIGKGASSEVFYAKHKILGLPVAIKGYPKTTMTTSNQRQIFE-HEAEILRSIENPYISALYDVFSDENNYYAVIDLAENG----SFESFIN--PT
|.|   ||.|....|. ..||  |  ||.|  .| .   . ... .   |..|....  |.|  |||.| |....| | ...|.|    .  ..|     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KPV--TENHAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFNI----KIVDFGVSTYY-DPNKPTKLPPVGSPAYMAPEVIL-HDVVTEKSDIWS
...  .|...|.|. |....| |.|| . |.|||.| .|||.|.  .|    || |||..  .   |..    ..|.| |||||||. .   . |.|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGVFLYFITAGIRPFDAE------DIPEICSNIVHGAVTFPSYLS---------------------PDLRDLLSKILVKDPKSRWSLEQIAEHPWL
.|. ||    |  ||. .      |  ..  .| .. . |... .                     ....|.....| ||||.|.. ||| .|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87054.m00118.AA AMPK 11-264 35 1.4e-64 190.62 In-house 1-254 (254) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-254/254
Sequence Identity: 35% (91 aa)

YEICYSIGKGASSEVFYAKHKILGLPVAIKGYPKTTMTTSNQRQIFEHEAEILRSIENPYISALYDVF-SDENNYYAVIDLAENGSFESFINPTKPVTEN
| |   ||.|..  |  ..|.. |  ||||   |. .. .   .  . | .||...  | |. ||.|  . .   . |.  . .|   ..|   . ..| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

HAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFNIKIVDFGVSTYYDPNKPTKLPPV-GSPAYMAPEVIL-HDVVTEKSDIWSAGVFLYFITAGI
 |.|.|.| ||...|.|  | | ||| |  |.|||   |||||||| | ..  .   .|    ||| | |||.|     .  . |||| || ||    | 
EACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG--EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGY

RPFDAEDIPEICSNIVHGAVTFPSYLSPDLRDLLSKILVKDPKSRWSLEQIAEHPWL
 ||| |..|.   .|. | .. |..|||. .||....| .||  | . ..| .|||.
LPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 87054.m00118.AA Ciliate-E2 11-264 23 1.8e-61 209.8 In-house 1-365 (365) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

YEICYSIGKGASSEVFYAKHKILG-LP-----------------VAIKGYPKTTMTTSNQRQIFEHEAEI---------------LRSIENPYISALYDV
|..   ||.|. . |...|..  . .                  |.|| | . .|  .. .||.  . ..               |... .|.|  .|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FS--DENNYYAVIDLAENGSFESFIN--PTK---------PVTENHAKRYFAQLIS---------------ALSYLHSVHHILHRDIKADNILLDRYFNI
|   |.||.| | .... |. ...|.  ..|         . ||...|....|...               || |||| ..|.||||| .|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIVDFGVSTYYDPN----------KPTKLPP----------------------VGSPAYMAPEVIL---------HDVVTEKSDIWSAGVFLYFITAGIR
||.||| |..||..          |  .                         .|.| |||||..          .   ..|.||||.|| ||.   | .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDAEDIPEICSNIVHG-AVTFP------------------SYLSPDLRDLLSK----ILVKDPKSRWS-LEQIAEHPWL
||          .. .   . ||                   ..|..  ||..|    .|.|||. | .  ||| .|||.
PF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 87054.m00118.AA Ciliate-E2-Unclassified 11-264 26 4.4e-60 205.91 In-house 1-352 (352) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)

YEICYSIGKGASSEVFYAKHKILG-------LPVAIKGYPKTTMT---------TSNQRQ------IFEHEAE-ILRSIENPYISALYDVFSDENNYYAV
|.| . ||.|. ..|. ..||  .       . ....   |  |.         . |...      . . ..  ||... .|.|  ....| |..| | |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKY-NKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

IDLAENGSFESFIN--PT---------------KPVTENHAK-----RYFAQLISALSYLHSVHHILHRDIKADNILLDRY---FNIKIVDFGVSTYYDP
 ...|.|. . .|.  ..               | .||..||     .||||....|.|||. ..|.||||| .|||.|     ..||| ||| | .|. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N--------------KPTKLPPV-GSPAYM----APEVILHDVVT----EKSDIWSAGVFLYFITAGIRPFDAEDIPE----------------ICSNIV
|              |. ..  . |.| ||    ||||.          .|.|||| || ||..  | .||....  .                . .|| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

HGAVTFPS--------YLSPDLRDLLS----KILVKDPKSRWSLEQIAEHPWL
 . . ||.         .||   |...    |.|.|.|..| ..||| .|||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 87054.m00118.AA QIK 11-264 33 7.3e-60 205.2 In-house 1-272 (272) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-272/272
Sequence Identity: 33% (92 aa)

YEICYSIGKGASSEVFYAKHKILGLPVAIKGYPKTTMTTSNQRQIFEHEAEILRSIENPYISALYDVFSDENNYYAVIDLAENGS-FESFINPTK-----
|.|   ||||    |  |.|.|    ||||   |. .. .|   ..  | .|. ... |.|  ||.|   ..  | | . ..||  |.  ..  .     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

--------------PVTENHAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFNIKIVDFGVSTYYDPNKPTKLPPVGSPAYMAPEVIL-HDVVTE
              |..|| |.| | |..||  |.|. ..| |||.|| |||||   ||||.||| | .. . .. .   .|||.| |||. .  .    
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHK-RNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMT-WCGSPPYAAPEMFEGKEYDGP

KSDIWSAGVFLYFITAGIRPFDAEDIPEICSNIVHGAVTFPSYLSPDLRDLLSKILVKDPKSRWSLEQIAEHPWL
|.|||| || ||   .|  ||| . ...  . .. | .  | ..| |. .|  . || ||. | . .|| .|.|.
KVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 87054.m00118.AA SAK 11-264 32 5.6e-52 175.18 In-house 1-254 (254) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-254/254
Sequence Identity: 32% (82 aa)

YEICYSIGKGASSEVFYAKHKILGLPVAIKGYPKTTMTTSNQRQIFEHEAEILRSIENPYISALYDVFSDENNYYAVIDLAENGSFESFINP-TKPVTEN
|..   .|||.   |. ||    .. ||||   |  |  .   |    | ||   .  | |  ||  | |.|  | |.....|| .. ...   .| ||.
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

HAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFNIKIVDFGVSTYYDPNKPTKLPPVGSPAYMAPEVILHDVVTEKSDIWSAGVFLYFITAGIRP
 |.... |..  . |||| | |.|||.   |||| |  ..|| |||. |     .   .   | | |..||..       .||.|| |  || .  |  |
EARHFMHQIVIGMLYLHS-HGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPP

FDAEDIPEICSNIVHGAVTFPSYLSPDLRDLLSKILVKDPKSRWSLEQIAEHPWL
|| . . .    ..      |..|| . .||. |.| |.|. | .|. .  ||..
FDTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase 87054.m00118.AA ULK 11-264 25 1e-50 174.82 In-house 1-329 (329) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-329/329
Sequence Identity: 25% (84 aa)

YEICYSIGKGASSEVFYAKHKIL----GLPVAIKGYPKTTMTTSNQRQI-------FEHEAEILRSIE--------NPYISALYDVFSDE--NNYYAVID
|..   .|||.   |. ...|.     .  ||.|  .| .|  .|. |        .. | .|.. .         .|.|  |||.| .   ||.| . .
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LAENGSFESFINPTKPVTENH----------AKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFN------------IKIVDFGVSTYYDPN---K
. . | .|..|.  |. .|..          |. .| |..... .||. | | ||||| .|||..  .             .|| ||| .   | .   .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

PTKLPPV------GSPAYMAPEVIL----HDVVT-EKSDIWSAGVFLYFITAGIRPFDAEDIPEIC-----SNIVH----------GAVTFPSY-----L
   .  |      |.| ||||...     .   .  |.|||| |. .| .  |  || |  . .       ..|                || .     .
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SPDLRDLLSKILVKDPKSRWSLEQIAEHPWL
||...||... |..|.| | | |.. .|||.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 87054.m00118.AA TyrKc 11-264 22 1.3e-16 45.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YEICYSIGKGASSEVFYAKHKILGLPVAIKGYPKTTMTTSNQRQIFEHEAEILRSI--ENPYISALYDVFSDE-------NNYYAVIDLAENGSFESFIN
 .    .| ||  ||. .. |   ..||.|   . .      |. | .||.|....  ..| | .|| | ...         .. |  ....|.  ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

PTKP-VTENHAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFNIKIVDFGVSTYYDPN------KPTKLPPV--GSP-----AYMAPEVILHDVV
 ..| ..  .   .  |  .  .||||  .. |||. | |.|... . .|| ||| | . .        | .. .    |.        ||||.| . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TEKSDIWSAGVFLY-FITAGIRPFDA-----EDIPEICSNIVHG-AVTFPSY--------LSPDLRDLLSKILVKDPKSRWSLEQIAEHPWL
|.|||.|| || ..   | |  |         .  |.  .. .|     | .         .... .. ..    ||..| . ..|  |  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 87054.m00118.AA Pkinase_Tyr 11-201 28 3.7e-16 55.34 Pfam 1-205 (270) Show / Hide 
Range on Protein: 11-201
Range on HMM: 1-205/270
Sequence Identity: 28% (60 aa)

YEICYSIGKGASSEVFYAKHK----ILGLPVAIKGYPKTTMTTSNQRQIFEHEAEILRSI-ENPYISALYDVFS-DENN--YYAVIDLAENGSFESFINP
 ..   .|.||  ||. .. |      ..|||.|  . ..|   | |. | .||.|....  .| |  || | . ..    .| |  ....|.  ..   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----TKPVTENHAKRYFAQLISALSYLHSVHHILHRDIKADNILLDRYFNIKIVDFGVST------YY-DPNKPTKLPPVGSPAYMAPEVILHDVVTEKS
     .|.|  .   . .|  ....||.| . . |||. | |.|... . .|| ||| .       ||    . .|||       ||||.| . . |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP----IKWMAPECINYGKFTTKS

DIWSAGVFLY
|.|| || ..
DVWSFGVLMW