Gene 88914.m00152 (T.vaginalis)

88914.m00152

Species: T.vaginalis
Alias: 88914.m00152, TvagK0596
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
88914.m00152.AA Protein None 361 None Fasta, JSON
88914.m00152.kin_dom Protein Kinase Domain None 288 None Fasta, JSON

Protein domain

Protein domains of 88914.m00152.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88914.m00152.AA ERK7 20-307 52 3.1e-158 531.99 In-house 1-292 (292) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-292/292
Sequence Identity: 52% (155 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQLVALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRAENDNDIYLAFEFMDTDVHTVIH-AGILLDV
|||.|..|||||||||.| |. |.| |||||.| ||.| .|||||.|||..|.... || |. |. | ||.|| ||||.||||.|| | ||  . || |.
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCINDMH----QDELLTDYIATRWYRAPEIIFGSSKYGPGIDMWAAGCILAEL
|..||..||| |.|..||. ||||||||||.|. |.  .||||||| | | .      |.  ||.|.||||||||||  || .| .|.|||  ||||.|.
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEM

VSGRPLFPGASTMDQLERVISFTGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFNPNKRPTAEQCLAHPYL
. |.|.||| |||.|.|...  .. | .||||...  .  .|| ..  ....  |.. . .. .|||||.|.| .|||.|| ||||.|.||| 
LRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 88914.m00152.AA MAPK 20-307 39 9.1e-148 497.2 In-house 1-328 (328) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-328/328
Sequence Identity: 39% (128 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQL------VALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRAE-----ND----NDIYLAFEFMDT
|.|.|..|.||||.|. | |. |.|       ||.||.. .|||.....|||||| ||| .. |. |..|| . ..|     |.    ||||. .|.|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DVHTVIHAGI-LLDVHQRYIFWQLLCA--LKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCIND-MHQDE-----------LLTDYIATRWYRAP
| | .|. .  | | | .|...|.|..  ||.||||.|||||||||| |. ..   |.|||||.|.| .  |...            .|.|.||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EIIFG--SSKYGPGIDMWAAGCILAELVS-GRPLFPGASTMDQLERVISFTGMPNKEDIESMQ-CPMVETMLGNLT-FSRPQL-VLEERLSG----ADPD
||...  . .|  ..|||..|||.||... ..||||| ...||........|.| .|.|. .. .... ... .|  . ...   .|. ...    |.|.
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

AIDLIKKLCQFNPNKRPTAEQCLAHPYL
||||..|. .|.|.|| |.|..|.|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 88914.m00152.AA CMGC 20-307 23 7.29999999999e-128 422.6 In-house 1-513 (513) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-513/513
Sequence Identity: 23% (122 aa)

YEIIKKVGKGAYGIVWRAQD--------------RVTGQLVALKKVFGAFQNVIDAQ----------RTYREITLLRQLK----------------SHPF
||||||.|.|.||.|....|              . |...||.||.. .| . ..|.          |..||| .|..|.                 |. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVGLLQVHRAEN---------------DNDIYLAFEFMDTDVHTVIHAG----------ILLDVH------------QRYIF------WQLLCALK--FI
||.|. . . .|               .|..|| ||.||.| . .|.             | . |             .|..      .|.|..||  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--VIHRDLKPSNMLIKSD--------------------SSIKVCDFGLSRCINDMHQD-------------------ELLTDYIATRWYRAPEIIF
||..  .|||||||.| || ..                      .|.|||||.| ... . .                   . .|.|..|||||||||..
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GS---------SKYGPGIDMWAAGCILAELVSG--------RPLFP-----------GASTMDQLERVISFTGMPN---------------KEDIESM--
|.          .|...||||..|||.||.. |        .||||           |.|. |||.. .   |.|.               .|.. .|  
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

-------------------QCPMVETMLGN-LTFSRPQL-VLEERLSG-----------------------------------ADPDAIDLIKKLCQFNP
                   ... . . . . ..| ...   ...   .                                   .||.||||.||. |..|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

NKRPTAEQCLAHPYL
.||.||||.|.|||.
DKRITAEQALQHPYF
Kinase 88914.m00152.AA ERK 20-307 43 1.1e-122 413.89 In-house 1-307 (307) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-307/307
Sequence Identity: 43% (133 aa)

YEIIKKVGKGAYGIVWRAQDRV-----TGQLVALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRAE---NDNDIYLAFEFMDTDVHTVIH
|.|||..|.||||.|  |.|       ||| || ||.. || . |.. ||.||| ||| .| |. |..|. . . .   . ||||. .|.|.|| | .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

AG-ILLDVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCINDMHQD------ELLTDYIATRWYRAPEIIFGSSKYGPGIDM
    | | |  |  .|.||.||.||||.|||||||||| |. |.   |.|||||.||..  .|.      . .|.|.||||||||||.   .||   .|.
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDI

WAAGCILAELVSGRPLFPGASTMDQLERVISFTGMP-NKEDIESMQCPMVETMLGNLTF-SRPQLVLEERLSGAD--PDAIDLIKKLCQFNPNKRPTAEQ
|..|||.||.. ..|||||.....|..|... .| |  .||..  . . .  .. || .  ||   .|.. . |.  |.||||..|. .|.|.|| |.|.
WSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEE

CLAHPYL
||.|||.
CLEHPYF
Kinase 88914.m00152.AA S_TKc 20-307 30 3.2e-102 346.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-231/231
Sequence Identity: 30% (93 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQLVALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRAENDNDIYLAFEFMDT---DVHTVIHAGI--
|||..|.||||.| |...... ||..||.|..          ....||| .|..   ||.|| |. | .    ...|. .|..|.   |....|.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LLDVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCINDMHQDELLTDYIATRWYRAPEIIFGSSKYGP-GIDMWAAG
     .   | |....|..|||...|| |.|||||||.| |. .   ||.|||||.| .         | .. |.||.|||..    .||.  .|.|. |
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCDWWSCG

CILAELVSGRPLFPGASTMDQLERVISFTGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFNPNKRPTAEQCLA-----
|||.|...|.|.||   .|... ..|                                          .|.|.|.|.|..|..|.||||| ..|.     
CILYEMLCGYPPFP---QMQMMFKKIG-----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--HPYL
  ||..
KCHPWF
Kinase 88914.m00152.AA p38 20-307 40 7.9e-99 334.63 In-house 1-289 (289) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-289/289
Sequence Identity: 40% (120 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQL---VALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRA-----ENDNDIYLAFEFMDTDVHTVIH
|. .. ||.|||| |  | || |||    || || .  || .|.| |||||. ||. .. |  ...|| |        .. .|.|.  .||..| . .. 
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

AGILLDVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCINDMHQDELLTDYIATRWYRAPEIIFGSSKYGPGIDMWAAGCIL
   | | | ...  |.| .||.|||||.|||||||||. .  |. ... ||||.|     |.|. .|.|.||||||||||..   .|   .|.|  |||.
CQRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-----HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIM

AELVSGRPLFPGASTMDQLERVISFTGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFNPNKRPTAEQCLAHPYL
|||..||.||||   .|||.|... .| | .| .. .|     . . ...  .|.  ... ..||.| ||||. |. .  | || |||. ..|||.
AELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYP-QMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase 88914.m00152.AA CDK 20-307 33 9.8e-98 313.27 In-house 1-284 (284) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-284/284
Sequence Identity: 33% (107 aa)

YEIIKKVGKGAYGIVWRAQDRVTG-----QLVALKKVFGAFQ-NVID----AQRTYREITLLRQLKSHPFIVGLLQVHRAEN---------DNDIYLAFE
||...|.| |.||.| .|.|. ||     |.|||||.    .   ..     . . |||.||..|  || || |. |   .|         .| .|. ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

FMDTDVHTVIHAGILLDVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSS-----IKVCDFGLSRCINDMHQ----DELLTDYIATRWYRAPEI
.||.|  ....         . ..|||| .| ..|| ...||||||.| || .. .     .|. ||||.|  . .||       .|  . |.||||||.
YMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

IFGSSKYG--PGIDMWAAGCILAELVS---GRPLFPGASTMDQLERVISFTGMPNKEDIESM-QCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIK
 .||..|.  ..||||..|||.||..    ..||||| |  |||.... . | |. ..  .. . |                              ||. 
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------------DLLN

KLCQFNPNKRPTAEQCLAHPYL
|. ...|.|| .|||.| |||.
KMLCYDPKKRISAEQALQHPYF
Kinase 88914.m00152.AA Pkinase 20-307 31 2.5e-94 324.49 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-293/293
Sequence Identity: 31% (96 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQLVALKKVFGAFQNVIDAQRTYR--EITLLRQLKSHPFIVGLLQVHRAENDNDIYLAFEFMDT-----DVHTVIH-
|.|..|.|.|..| |...... ||..||.|..    ..    |.  |  || ... | .||.|| |. . .   ...||. .|...      | ...|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

--AGIL--LDVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSI----KVCDFGLSRCINDMHQDELLTDYIATRWYRAPEIIFGSSKYGPGID
   | .   . . . ...|.|..|...|| |.|||||||.| ||...  |    |.|||||.....    .. .|..  |.||.|||.| |...||| .|
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

MWAAGCILAELVSGRPLFPGA----STMDQLERVISFTGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFNPNKRPTAE
||..||||.|...|||.|||.    . .||....    | |...|..   ... .. .   . .     ....   ......|.||......|.||||||
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAE

QCLAHPYL
|.| ||..
QILQHPWF
Kinase 88914.m00152.AA RCK 20-307 35 1.4e-82 261.84 In-house 1-298 (298) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-298/298
Sequence Identity: 35% (108 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQLVALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRAENDNDIYLAFEFMDTDVHTVIHA----GIL
| |||..|.|.|| |  ||.  ||..|| ||    | .  ....  |||. || |. || |. |. | | ...   |. ||.||...   .      . .
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMN-LREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKY

LDVHQ---RYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKS---------DSSIKVCDFGLSRCINDMHQDELLTDYIATRWYRAPEIIFGSSKYGPGID
|   |   . |. |.| .|...|. |  |||||| | ....         .  ||..||||.|.| . .     |||. ||||||||..  . .|   .|
LPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPP---YTDYVSTRWYRAPECLLRCTYYNSPMD

MWAAGCILAELVSGRPLFPGASTMDQLERVISFTGMPNKED-IESM-QCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFNPNKRPTAEQC
.|| ||| .|| . ||||||.| .||.   ..  | |||.|  .   .. ... ....         |.. .. . .|.|.|..|..| .|.||.||.|.
IWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCK----GMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQA

LAHPYL
| ||| 
LQHPYF
Kinase 88914.m00152.AA ERK1 20-307 41 1.9e-81 276.91 In-house 1-289 (289) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-289/289
Sequence Identity: 41% (123 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQLVALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRA---ENDNDIYLAFEFMDTDVHTVIHAGILL
|  .. .|.||||.|  |.|.|..| ||.||.   |      ||| |||..|   | |  |... .. ||   |.  |.|.  . |.||.  .. .  | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFK-HENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

DVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCINDMHQDE--LLTDYIATRWYRAPEIIFGSSKYGPGIDMWAAGCILAEL
  |  |  .|.|  ||.|||| |.||||||||.|.     .|.||||| | | | ..|    ||.|.||||||||||.  |  |   ||.|. ||||||.
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEM

VSGRPLFPGASTMDQLERVISFTGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFNPNKRPTAEQCLAHPYL
.| ||.|||   .|||  ...  | | ..|.. .        |  | . .|.. ...   .||. |.||. |.  |||.|| | |. ||||||
LSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPH-KPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase 88914.m00152.AA ERK5 20-307 37 9.3e-80 271.28 In-house 1-295 (295) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-295/295
Sequence Identity: 37% (111 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQLVALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRAEND----NDIYLAFEFMDTDVHTVIHAGIL
|.|| |.| ||||.|  |  | .|| ||.||.  ||  |  |.||.||. .||  . |  |. . .. . .       |.|  |. |. |.| .||.   
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

LDV-HQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCIND---MHQDELLTDYIATRWYRAPEIIFGSSKYGPGIDMWAAGCIL
. . | ||  .|.|  ||..||| ||||||||||.|.     .|. |||. | .      ..   .|.|.|||||||||..| |  |   ||.|. |||.
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIF

AELVSGRPLFPGASTMDQLERVISFTGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFNPNKRPTAEQCLAHPYL
 |... | .|||   ..||. ..   |||    |...    |   .      |    .|.   .||. |.||. ..  | | .| |. . | ||.|
GEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase 88914.m00152.AA MAPK-Unclassified 20-166 42 1.2e-52 181.19 In-house 1-157 (575) Show / Hide 
Range on Protein: 20-166
Range on HMM: 1-157/575
Sequence Identity: 42% (67 aa)

YEIIKKVGKGAYGIVWRAQDRVT-GQLVALKKVFGAFQNVIDAQRTYREITLLRQLKSHPFIVGLLQVHRAENDND-----IYLAFEFMDT---DVHTVI
|| .| .| ||||.| || |  . .| || ||| ..|.|..|. |. ||| .|| | .|| |. .  . ... .       ||.  ..| |   | | .|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYL-NHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

HAGI--LLDVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSR
.  .  . . | .|.| |.|  || .|||..||||||||| ||  | |...||||.||
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase 88914.m00152.AA MAPK-Unclassified 168-307 30 1.8e-38 134.16 In-house 396-575 (575) Show / Hide 
Range on Protein: 168-307
Range on HMM: 396-575/575
Sequence Identity: 30% (55 aa)

INDMHQDELLTDYIATRWYRAPEIIFGSSKYGPGIDMWAAGCILAELVSG-----------RPLFPGAS--------------------TMDQLERVISF
||| |    .| |..|||||||||.. .. |.  .|.|..|||.||...            |||||| .                      ||.   .. 
INDCHHCYHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDY

TGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGAD---------PDAIDLIKKLCQFNPNKRPTAEQCLAHPYL
 |||..||.   .|. .   .  .    |  . .   . |          ...||...|. ||||.|| ||.| | ||| 
LGMPPEEDCNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase 88914.m00152.AA TyrKc 20-307 23 1.3e-14 13.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-280/280
Sequence Identity: 23% (73 aa)

YEIIKKVGKGAYGIVWRAQDRVTGQLVALKKVF-GAFQNVIDAQRTYREITLLRQL-KSHPFIVGLLQVHRAE-----NDNDIYLAFEFMDT-DVHTVIH
 . .|| | ||.|.|.... .   . || |..  .|       .  .||. ....| ..|| || |. | . .      .  ... .|.|.  | .  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AGI--LLDVHQRYIFWQLLCALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSRCINDM-----HQDEL------LTDY-IATRWYRAPEIIFGSSK
.    |   .  .. ||  |   ..|| ..|||||   | |....  .|..|||||| | |       .|         ... .  ||. ||| |   .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGK

YGPGIDMWAAGCILAELVS-GRPLFPG-----ASTMDQLERVISFTGMPNKEDIESMQCPMVETMLGNLTFSRPQLVLEERLSGADPDAIDLIKKLCQFN
. .  | |. |  . |. . | .  ||      |  . .|.| .   ||  ....    ||                      .. ..  ...|. ....
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----PMS-------------------FVCCPDEMYQIMKQCWHED

PNKRPTAEQCLAHPYL
|..||| ...  | ..
PEDRPTFSEI--HECF
Kinase 88914.m00152.AA Pkinase_Tyr 129-166 39 0.001264 12.9 Pfam 122-159 (270) Show / Hide 
Range on Protein: 129-166
Range on HMM: 122-159/270
Sequence Identity: 39% (15 aa)

CALKFIHSAGVIHRDLKPSNMLIKSDSSIKVCDFGLSR
... . .| . |||||   | |....  .|.|||||.|
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 88914.m00152.AA Pkinase_Tyr 20-51 30 0.03128 8.18 Pfam 1-36 (270) Show / Hide 
Range on Protein: 20-51
Range on HMM: 1-36/270
Sequence Identity: 30% (11 aa)

YEIIKKVGKGAYGIVWRAQDR----VTGQLVALKKV
 ...|| |.||.| |...  .     |.. || |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML