Gene 84337.m00149 (T.vaginalis)

84337.m00149

Species: T.vaginalis
Alias: 84337.m00149, TvagK0806
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
84337.m00149.AA Protein None 425 None Fasta, JSON
84337.m00149.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of 84337.m00149.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84337.m00149.AA STE 10-268 26 2.2e-83 283.33 In-house 1-359 (359) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-359/359
Sequence Identity: 26% (98 aa)

YEILHQVGRGMYSNVYEAKCL------ANQQT---------LCVKIINLEDF----------------PYPLENIQKQTSMWSKSS--DPNIVQYYGSFV
.|.. ..|.| .  || |..        ....           .|..|||.                 .  ...|.|  .. .|..   ||||.|||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TGA-------QVWILTEFMDAGSLEDILKYGYPRGIKD-----------ELACANIINGFLKA-LDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLAT
 .        ..||  |.||.|||.||.|  | .|  .           |   | |.   ||. |.| |. | ||| .|. |.||     .||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SLIQGGV-------------RKQACLSMFGDACYMSPEILKNG-----EGYTCKSDIWSFGLTVIEIATGKMPYQGMKFM----------------ESIV
.|.. .              ..| . .. |   .|.||.....      ||..|.||||.|.|.|| |||| |.  |. |                | . 
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-

NIMEKEAPELP-------------------AEFSAPFRDFVKRCLTMDPQKRATSEELLN--HRFL
.|.... | ||                    ..| .|.||...||..||.||.|...||.  | |.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 84337.m00149.AA STE20 10-268 34 6.1e-82 278.54 In-house 1-288 (288) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-288/288
Sequence Identity: 34% (101 aa)

YEILHQVGRGMYSNVYEAKCLANQQT----LCVKIINLEDFPYP---LENIQKQTSMWSKSSDPNIVQYYGSFVTG----AQVWILTEFMDAGSLEDILK
||.|...|.| |  || | .  ...      ..|..|||.   .   .|.|||  |. ...  ||||.||||.. .     . ||. |....||| ||.|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

YGYPRGIK------DELACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQ-GGVRKQAC---LSMFGDACYMSPEILKNG-
  ...|..      .|   | |  . |..||| |. |.||| .|. |.||...||.||.|||.. .|.. |. .        .. |  ..|.||...   
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCME

---EGYTCKSDIWSFGLTVIEIATGKMPYQGMKFMESIVNIM--EKEAPELPA----EFSAPFRDFVKRCLTMDPQKRATSEELLNHRFL
    ||..|.||||.| | || |.|. ||  |  |  .  |    .. |.|       .|  |.|||..||..||.||.|...||.| |.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 84337.m00149.AA FRAY 10-268 33 1.3e-68 212.13 In-house 1-277 (277) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-277/277
Sequence Identity: 33% (93 aa)

YEILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFP-YPLENIQKQTSMWSKSSDPNIVQYYGSFVTGAQVWILTEFMDAGSLEDILKYGYPRGIK--
||    .| |    |..| |.  |    .|.||||      .. . |     .  . ||.|.|. |||   . |.   . ..||. ||.|. .|.|..  
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

----DELACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQGG--VRKQACLSMFGDACYMSPEILKNGEGYTCKSDIWSFG
    ||   | |    ||.|.|||.  |||| .|. |.|. . |   ..|||    |..||   |.     . |  | | ||..   .||  | ||||||
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

LTVIEIATGKMPYQGMKFMESIVNIMEKEAPELPAE---------FSAPFRDFVKRCLTMDPQKRATSEELLNHRFL
 | ||.|||| ||     |   ...   . | |  .         ..  |.. .. ||  ||.|| |  ||| |.| 
ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase 84337.m00149.AA S_TKc 10-268 27 6.3e-65 222.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-231/231
Sequence Identity: 27% (76 aa)

YEILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFPYPLENIQKQTSMWSKSSDPNIVQYYGSFVTGAQVWILTEFMDA--GSLEDILKYGYPRGI--
|||| ..|.| .. || ..    ..   .|||.        |.|..  .. .|   ||||..|..|..   ... .|..|   |.| |..|   ..|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-KDELACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQGGVRKQACLSMFGDACYMSPEILKNGEGYTC-KSDIWSFGLTV
  .|  .. ..   ..||.| |. . ||| .|  |.||..  . |..|||||. |           .. |   ||.||.|    ||.. |.|.||.| ..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

IEIATGKMPYQGMKFMESIVNIMEKEAPELPAEFSAPFRDFVKRCLTMDPQKRATSEELLN-------HRFL
.| ..|. |..    |. . ...           | ...||...||..||.|| |  |.|.       | ..
YEMLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84337.m00149.AA YSK 10-268 34 1e-63 190.55 In-house 1-257 (257) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-257/257
Sequence Identity: 34% (90 aa)

YEILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFPYPLENIQKQTSMWSKSSDPNIVQYYGSFVTGAQVWILTEFMDAGSLEDILKYGYPRGIKDEL
. ..  .||| .  || .     |..  .|||.||.     | ||.     |    |.| .||||.  .   ||  |.   ||. | .|  |  |  || 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKY-VGQFDEK

ACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQGGVRKQACLSMFGDACYMSPEILKNG-EGYTCKSDIWSFGLTVIEIAT
  | |.   ||.||| |    ||| .|. ||||. .|. || ||| |  . .   . .    . |   .| ||. . .  .|  | |||| | | .|.|.
YIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNT---FVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAK

GKMPYQGMKFMESIVNIMEKEAPELPA-EFSAPFRDFVKRCLTMDPQKRATSEELLNHRFL
|  ||  .. |    .|  .. |.|   ..| .| .||  ||  ||..| . .||| |.| 
GEPPYCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 84337.m00149.AA MST 10-268 33 2.8e-61 193.51 In-house 1-254 (254) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-254/254
Sequence Identity: 33% (88 aa)

YEILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFPYPLENIQKQTSMWSKSSDPNIVQYYGSFV--TGAQVWILTEFMDAGSLEDILKYGYPRGIKD
..|.   |.| |  || | .. . . . .|... .     |..| |  |. .    ..||.||||.      ..|| .|. ..||. || |        .
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNE---DLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

ELACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQGGVRKQACLSMFGDACYMSPEILKNGEGYTCKSDIWSFGLTVIEIA
. ||  |  . |. |.| |. . |||  |. | ||| .||.||.||| .  |.     ..   .  |  ..|.|| . .  .|.|| |||| | | || |
QIAC--ILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRN---TVIGTPYWMAPEVIQE-IKYDCKADIWSLGITAIEMA

TGKMPYQGMKFMESIVNIMEKEAPEL--PAEFSAPFRDFVKRCLTMDPQKRATSEELLNHRFL
 |. ||   . |  .  |  |  | .  | ..|  | |||..||. .|..|.|.|.||.| | 
EGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 84337.m00149.AA STE7-Unclassified 66-268 33 4.2e-58 199.35 In-house 65-301 (301) Show / Hide 
Range on Protein: 66-268
Range on HMM: 65-301/301
Sequence Identity: 33% (81 aa)

PNIVQYYGSFVTGAQ---VWILTEFMDAGSLE---DILKYGY-----PRGIKDELACANIINGFLKALDYFHRCH-QIHRNVKSCNVLLNSKGEAKLSDF
|.||.||| ...      . |. |.|| |||.   ||.| .|     . |. .|.  . | .. ...|.| |. | .||| .|  |.|.||||..|..||
PYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKIDIYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDF

GLATSLIQGGVRKQACLSMFGDACYMSPEILKNGE-----GYTCKSDIWSFGLTVIEIATGKMPY---------------QGMKFMESIVNIMEKEAPEL
| .  | .  .... .  . |   |||||... |.     .|. ||||||.||| .| |||| ||                .| | |   .|.....|.|
GVCGQL-ENTLDEAKT--WVGCQMYMSPERIQ-GQMPHRPSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRL

PA-----EFSAPFRDFVKRCLTMDPQKRATSEELLN-HRFL
|       .|. |.||...|.  .|  |... .||| | ..
PDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNEHPWI
Kinase 84337.m00149.AA Pkinase 10-268 24 6.1e-53 186.99 Pfam 1-293 (293) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

YEILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFPYPLE-------NIQKQTSMWSKSSDPNIVQYYGSFVTGAQVWILTEFMDAG----SLEDILK
|.|. ..|.| .. ||...   .... .||||....     .        ||   .. .    ||||..|..| ..  ... .|... |    .| |...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

YGYPRGIK--DELACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEA----KLSDFGLATSLIQGGVRKQACLSMFGDACYMSPEILKNGEGYTC
    .|    .|  | ...   |..|.| |..  ||| .|. |.|....|.     |..|||||  .     ... . .  |   ||.||... |..|. 
T-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDIWSFGLTVIEIATGKMPYQGM----KFMESIVNIMEKEAPELPAEFS-----------------------APFRDFVKRCLTMDPQKRATSEELLNH
|.|.||.|....| ..|. |..|     . .. .. | ..  |.|. ...                        ...||.|.||..||.|| | |..|.|
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

RFL
 ..
PWF
Kinase 84337.m00149.AA KHS 10-268 33 5.9e-49 162.74 In-house 1-258 (258) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-258/258
Sequence Identity: 33% (88 aa)

YEILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFPYPLENIQKQTSMWSKSSDPNIVQYYGSFVTGAQVWILTEFMDAGSLEDILKYGYPRGIKDEL
||.| .|| | | .|| |.  . ..   ||.| .|     .. ||.   |  . . |||| |.||..   ..||  |.  .||| || .     |   ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDD-FAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHV---TGPLSEL

ACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQGGVRKQACLSMFGDACYMSPEI--LKNGEGYTCKSDIWSFGLTVIEIA
  | .    |..|.|.|   ..|| .|  |.||...|. || |||... . .   ...   |  |   .| ||.   .   ||    |||. |.| ||.|
QIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRK---SFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELA

TGKMPYQGMKFMESIVNIMEKEAPELP-----AEFSAPFRDFVKRCLTMDPQKRATSEELLNHRFL
  . |   .  |  .  .| | . . |       .|. | .||| .|| .|.|| |.| ||.| |.
ELQPPMFDLHPMRALF-LMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 84337.m00149.AA PAKA 10-268 30 2.3e-48 166.98 In-house 1-260 (260) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-260/260
Sequence Identity: 30% (80 aa)

YEILHQVGRGMYSNVYEAKCLANQQT--LCVKIINLEDFPYPLENIQKQTSMWSKSSDPNIVQYYGSFVTGAQVWILTEFMDAGSLEDILKYGYPRGIK-
|. . ..| |    ||.|. ....|.    .| .|... |   |.|    ..  ..  .|||.|. |..   . |.  |.|..|.| |...      .  
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPK-KELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

-DELACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQGGVRKQACLSMFGDACYMSPEILKNGEGYTCKSDIWSFGLTVIE
 ||   | ..   |..|.. |. |.||| .|| |.||.. |. |. ||| .. | |   ...   .| |   .|.||.. ..  |  | |||| |  .||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRN---TMVGTPYWMAPEVI-RRKQYDEKVDIWSLGIMAIE

IATGKMPYQGMKFMESIVNIMEKEAPEL--PAEFSAPFRDFVKRCLTMDPQKRATSEELLNHRFL
.. |  ||  ..    .  |  . .|..  |. .|  |.||...|| .|...||...|||.| ||
MIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 84337.m00149.AA TKL 16-266 16 4.3e-48 166.1 In-house 1-364 (364) Show / Hide 
Range on Protein: 16-266
Range on HMM: 1-364/364
Sequence Identity: 16% (63 aa)

VGRGMYSNVYEAKCLANQ--------QTLCVKIINLEDFPYPL--------------------------ENIQKQTSMWSKSSDPNIVQYYGSFVTGAQ-
.|.| .. || .|.  .         ..  ||... ..                               . . ... | |. . |||||..|.   . . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VWILTEFMDAGSLEDILKYGYPRGIKDELACANIINGFLKALDYFHRCH--------QIHRNVKSCNVLLNSKGE-------------
             .| .|... |||...|               ... .  ....| | ..         |||. || |.|......             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-AKLSDFGLATSLIQGG----------------VRKQACLSMFGDACYMSPEILKNG---------------EGYTCKSDIWSFGLTVIEIATGKMPYQG
 .|..||||.... | |                .....  .  |  ..|.||.|..                . |. |.|..|||.   ||.|.. ||..
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

MKFMES----------IVNIMEKEAPELP------------AEFSAPFRDFVKRCLTMDPQKRATSEELLNHR
...|.           .... ... |..|              .  ....  ..|  .||.|| . .|.| . 
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 84337.m00149.AA STE7 178-268 34 2.9e-36 126.8 In-house 177-288 (288) Show / Hide 
Range on Protein: 178-268
Range on HMM: 177-288/288
Sequence Identity: 34% (39 aa)

YMSPEILK-NGEGYTCKSDIWSFGLTV-IEIATGKMPY-------------------QGMKFMESIVNIMEK-EAPELPAEFSAPFRDFVKRCLTMDPQK
||.|| .  | ..|. .||.||.|.|  ||.|||. ||                   . | ..| . .|..  ..|.|| .||..|.|||..||. ||..
YMAPERIDGNKQHYDVRSDVWSLGITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPE-MAIFEQLTCIVNENPPPRLP-KFSPEFQDFVNKCLQKDPNE

RATSEELLN-HRFL
|.. ..|.. | |.
RPKYHQLMKEHPFI
Kinase 84337.m00149.AA STE7 11-154 35 6.4e-19 65.72 In-house 2-156 (288) Show / Hide 
Range on Protein: 11-154
Range on HMM: 2-156/288
Sequence Identity: 35% (56 aa)

EILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFPYPLENIQKQTSM----WSKSS-DPNIVQYYGSFVTGAQ--VWILTEFMDAGSLE---DILKYG
|.. ..|.|.| .|| .    ... . || |.|..     ...|||  |      |..  |.|||.|| |.|     .||  |.|| |.|.   ...| .
EHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNND---PEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKV

YPRGI----KDELACANIINGFLKALDYFHR-CHQIHRNVKSCNVLLNSKGEAKLSDFG
| |||      |   . |    .|.|.| |.  . ||| ||  |.|.||.|. ||.|||
Y-RGIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFG
Kinase 84337.m00149.AA TyrKc 10-268 23 2.4e-16 41.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YEILHQVGRGMYSNVYEAKCLANQQTLCVKIINLEDFPYPLENIQKQTSMWSKS--SDPNIVQYYGSFVTG-------AQVWILTEFMDAGSLEDILKYG
 . ... |.| .  ||...     ..  || .. .     .| . .  .. .|   . ||||. ||  ...        ...|..|.|. |.| | |.. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

YPRGIKDELACANIINGFLKALDYFHRCHQIHRNVKSCNVLLNSKGEAKLSDFGLATSLIQG---GVRKQACLSMFGDACY-------MSPEILKNGEGY
 |.         ..     .  .| |. . |||     |.|..... .| |||||.  .  .   |..|.   .. .. .        |.|| .. |. .
RPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-F

TCKSDIWSFGLTVIEIAT-GKMPYQG-----MKFMESIVNIMEKEAPELPAE--------FSAPFRDFVKRCLTMDPQKRATSEELLNHRFL
| |||.|||| .  || | |..|| |     |.  | | .... . .. |..         ..   .  |.|   || .| | .|.  |...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 84337.m00149.AA Pkinase_Tyr 179-217 48 1.8e-11 39.44 Pfam 181-220 (270) Show / Hide 
Range on Protein: 179-217
Range on HMM: 181-220/270
Sequence Identity: 48% (20 aa)

MSPEILKNGEGYTCKSDIWSFGLTVIEIAT-GKMP-YQGMK
|.|| ...|. .| |||.|||| .  || | |..| |.||.
MAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMS
Kinase 84337.m00149.AA Pkinase_Tyr 66-98 38 0.001081 13.13 Pfam 64-99 (270) Show / Hide 
Range on Protein: 66-98
Range on HMM: 64-99/270
Sequence Identity: 38% (14 aa)

PNIVQYYGSFV-TGAQ--VWILTEFMDAGSLEDILK
||||..||  .  | .  ..| .|.|  |.| | |.
PNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR
Kinase 84337.m00149.AA Pkinase_Tyr 139-156 44 0.00939 9.95 Pfam 141-158 (270) Show / Hide 
Range on Protein: 139-156
Range on HMM: 141-158/270
Sequence Identity: 44% (8 aa)

NVLLNSKGEAKLSDFGLA
|.|..... .| .|||||
NCLVTENNVVKICDFGLA