Gene 82761.m00542 (T.vaginalis)

82761.m00542

Species: T.vaginalis
Alias: TvagK0583, 82761.m00542
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
82761.m00542.AA Protein None 307 None Fasta, JSON
82761.m00542.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of 82761.m00542.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82761.m00542.AA CDC2 5-286 51 2.3e-175 543.93 In-house 1-301 (301) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-301/301
Sequence Identity: 51% (155 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEEG--IPPTSVRENSILSELS-HPNVVSVKEVINTPFSLILIMEYLDKDLKNYLA---TQHGP
|...||.|||||| |||.... |..| |.| | ||||.||  .| |..|| |.| ||  |||.|. ..||    .| .. |||| |||.|.     .  .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

INPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYT--KDVITLWYRAPEILLDAPAYDLSVDVWSVGCIIAEM
. | |.|||.|||| |...|| ..|.||| ||||.|... | ||. |||||| .. |.|.||  ..|.||||||||||| .  |...||.||.|||.|||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---MNRTPLFPGDSEIDQLYTIFKILGTPTESEWPGVSQFPNYSAEFPKWLKLDLSEKIQT---------NDQLALDLISKMLQYDPVKRITAKDALDHP
   ... |||.||||||||. ||.|||||.|..||||.|.| | . ||.| . |||. .           .|. ..||...|||||| |||.||.||.||
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

YF
||
YF
Kinase 82761.m00542.AA CDK 5-286 46 2.2e-156 503.99 In-house 1-284 (284) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-284/284
Sequence Identity: 46% (148 aa)

YERLEKLGEGTYGAVYKARNKTTG-----EILAMKVIHLEQ-----EEEGIPPTSVRENSILSELSHPNVVSVKEVINTP-----------FSLILIMEY
||.|||.|||||| |||||.| ||     .| |.| | .|.     |.||.| |..|| |.| || |||.|....|. |             .| ...||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LDKDLKNYLATQHGPINPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGF-----IKLCDFGLARPISL------PMRAYTKDVITLWYRAPE
.| ||| |.           ||.| .|.| ||.||| ..|.|||.||||.|.|. |      .|. ||||||  .       |.|.||. |.||||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

ILLDAPAYD--LSVDVWSVGCIIAEMMN---RTPLFPGDSEIDQLYTIFKILGTPTESEWPGVSQFPNYSAEFPKWLKLDLSEKIQTNDQLALDLISKML
.|| .  |.   ..|.||||||.|||..   | ||||||||||||  ||.|.|||||. ||||...|.|                        ||..|||
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKML

QYDPVKRITAKDALDHPYF
.||| |||.|..||.||||
CYDPKKRISAEQALQHPYF
Kinase 82761.m00542.AA CDK5 5-286 47 2.6e-144 459.2 In-house 1-287 (287) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-287/287
Sequence Identity: 47% (137 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEEGIPPTSVRENSILSELSHPNVVSVKEVINTPFSLILIMEYLDKDLKNYLATQHGPINPMLI
||..||.|||||| |||||||.|.|| |.| . |..| ||.| | .|| ..| || |.|.|    || .   |.|. |..|.||| |.    | ... .|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYTKDVITLWYRAPEILLDAPAYDLSVDVWSVGCIIAEMM-NRTPLF
||. || | ||..|| . . |||.|||||| |. |  || ||||||    | | |.  |.|||||.| .|. .  |  |.|.||.|||.|||. .  |||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGDSEIDQLYTIFKILGTPTESEWPGVSQFPNYS---AEFPKWLKLD-LSEKIQTNDQLALDLISKMLQYDPVKRITAKDALDHPYF
|| .. |||  ||||.|||.|..||.... |.|     ..|..     ... ..  |.  .|| .||||..| .||.||.|| ||||
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 82761.m00542.AA CDK7 5-286 42 1.4e-136 366.44 In-house 1-288 (288) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-288/288
Sequence Identity: 42% (121 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIH----LEQEEEGIPPTSVRENSILSELSHPNVVSVKEVINTPFSLILIMEYLDKDLKNYLATQHGPIN
|| ....|||... ||||. . ||.| | | |      .. . ||  | .||  || |..|.||.    ..    .. |.....| ||      .     
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYTKDVITLWYRAPEILLDAPAYDLSVDVWSVGCIIAEMMNRT
|  ||.|. ..| || |||   | |||.|| |||.|  | .|. |||||| .  | |.||  |.| |||||| |  |  |  .||.||||||.|| | |.
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PLFPGDSEIDQLYTIFKILGTPTESEWPGVSQFPNYSA--EFPKWLKLDLSEKIQTNDQLALDLISKMLQYDPVKRITAKDALDHPYF
| .||||.||||  ||..||||||.|||.......|    .||   .  | .      . .|||...|.  .|.||.|. ..| .|||
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 82761.m00542.AA CMGC 5-286 28 2.5e-133 440.87 In-house 1-513 (513) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-513/513
Sequence Identity: 28% (147 aa)

YERLEKLGEGTYGAVYKARN--------------KTTGEILAMKVI----HLEQ-----EEEGIPPTSVRENSILSELS-----------------HPNV
|| ..|.|||||| |||.|.              . |.|| |.| |    . ||     |..|.| .. || .|| .|.                 |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VSVKEVINTP-----------------FSLILIMEYLDKDLKNYLATQHG--------PINPML------------IKSYA------YQILAGLS--YCH
|. .... ..                  .| |..||.|.||..|.  ...        | ..              ||..       |||| ||   |||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

CQG--IIHRDMKPQNLLLNRG--------------------GFIKLCDFGLARPISLP---------------------MRAYTKDVITLWYRAPEILLD
 ..  |||||.||.|.|.|                      | .|.||||||| .. .                     .|.|| .| |.||||||||| 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

APAYD---------LSVDVWSVGCIIAEMMNR--------TPLFPGDSE-----------IDQLYTIFKILGTPT---------------ESEWPGVSQF
.. |.          ..|.||||||.|||...         |||||.||           ||||. |||.|||||               | |||.... 
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PNY----------------SAE----------FPKWLKLDLSEKIQT-----------------------------------NDQLALDLISKMLQYDPV
|.|                |            ||.| . ......                                      |..|.||..||||||| 
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRITAKDALDHPYF
|||||..||.||||
KRITAEQALQHPYF
Kinase 82761.m00542.AA PITSLRE 5-286 44 6.4e-112 378.13 In-house 1-295 (295) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-295/295
Sequence Identity: 44% (130 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLE--QEEEGIPPTSVRENS-ILSELSHPNVVSVKEVI--NTPFSLILIMEYLDKDLKNYLATQH---
.. | . .||||| ||.|..| |.|| |.| . .|  .| ||.| ||.|| . || .| |||.|.|||..   .  .  ..|||.. |||  . . .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

GPINPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYTKDVITLWYRAPEILLDAPAYDLSVDVWSVGCIIAEM
 |  |  ||.   | | | .. |   |.||| |  |||..  |  |.|||||||    |...||. |.||||||||.||... |   ||.|||||| ||.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

MNRTPLFPGDSEIDQLYTIFKILGTPTESEWPGVSQFPNYSA-E-FPKWLKLDLSEKIQ---TNDQLALDLISKMLQYDPVKRITAKDALDHPYF
.   |||.|.|||||.  ||| .|||||. |||.. .|.  . . ||.     | ....   .  . ..||  .|| |.| .|||| |||.||.|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 82761.m00542.AA PFTAIRE 5-286 44 8.70000000001e-108 364.4 In-house 1-287 (287) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-287/287
Sequence Identity: 44% (128 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEEGIPPTSVRENSILSELSHPNVVSVKEVINTPFSLILIMEYLDKDLKNYLATQHGPINPMLI
||.|||||||.|  |||.. . .. . |.|.| | |.||| | | .|| | | .| | |.|    .| |   | .. ||...||. |.    | ..|  .
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRL-QQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

KSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYTKDVITLWYRAPEILLDAPAYDLSVDVWSVGCIIAEMMNRTPLFP
. . .| | |||||| . . |||.||||||.   |  || ||||||  | | . | . |.||||| | .|| .  |  ..|.| ||||  |||   |.||
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GD-SEIDQLYTIFKILGTPTESEWPGVSQFPNYSAEFPK---WLKLDLSEKIQTND--QLALDLISKMLQYDPVKRITAKDALDHPYF
|     |||  |||.||||||  ||||...|||  .  .        | . .   .    | ||..||||. | .|. |..|. ||||
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 82761.m00542.AA Pkinase 5-286 35 3e-107 367.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEEGIPPTSVR--ENSILSELSHPNVVSVKEVINTPFSLILIMEYLDK-----DLKNYLA-TQH
|....|.|.|..| |||...| ||.| |.|.| .. |... . | .|  | .|. .|.|||.|  ...  .. .. ..|||...     ||. |.   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPI--NPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFI----KLCDFGLARPI-SLPMRAYTKDVITLWYRAPEILLDAPAYDLSVDVWSV
|..   .  .|.|.|||| || ||| .||||||.||.|.|... | |    |.||||||. .   . . .|  . |.||.|||...... |. .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIIAEMMNRTPLFPGD----SEIDQLYTIFKILGTPTESEWPGVSQFPNYSAEFPKWLKLDLSEKIQTNDQLALDLISKMLQYDPVKRITAKDALDHPY
|||..||... |.|||.    . .||.. |..|.|.|....||  .  ....  .. | .  ....    .. ..|.|...|..|| ||.||...| ||.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 82761.m00542.AA PCTAIRE 5-286 44 3.4e-106 359.12 In-house 1-291 (291) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-291/291
Sequence Identity: 44% (129 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEEGIPPTSVRENSILSELSHPNVVSVKEVINTPFSLILIMEYLDKDLKNYLATQHGPINPMLI
| .|.|||||||  ||| | | |. . |.| | ||  ||| | | .|| | | .| | |.|.   .| |  .| |. ||.|.||| |.      .|   .
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

KSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYTKDVITLWYRAPEILLDAPAYDLSVDVWSVGCIIAEMMNRTPLFP
| . .|.| || ||| . | |||.||||||.|  |  || ||||||  | | . | ..|.||||| |..|.    |  ..|.| |||| .||    ||||
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFP

GDS------EIDQLYTIFKILGTPTESEWPGVSQFPNYSAE-FPKWLKLDLSEKIQTND---QLALDLISKMLQYDPVKRITAKDALDHPYF
|          |||  ||.|||||.|  ||||. .... .. ||..... |       |   .   ||....||| . .|. | .|. ||||
GSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase 82761.m00542.AA S_TKc 5-286 34 5.5e-103 349.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-231/231
Sequence Identity: 34% (104 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEEGIPPTSVRENSILSELSHPNVVSVKEVINTPFSLILIMEYLDK---DLKNYLATQHGP---
|| |.|.|.|..| |||.|.| ||.| |.|.|.          .  || .||..  |||.|  ..|. .  .| ..|||.|    ||. |.  . ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--INPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYTKDVITLWYRAPEILLDAPAYDL-SVDVWSVGCIIAE
  ...  ...|.|||. .| ||| .|||||| ||.|.||..   ||.||||||| .       |  . |.||.|||.|     |.  ..|.||.|||..|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MMNRTPLFPGDSEIDQLYTIFKILGTPTESEWPGVSQFPNYSAEFPKWLKLDLSEKIQTNDQLALDLISKMLQYDPVKRITAKDALD-------HPYF
|. . |.||      |....||..|                                   .. |.|.|.|.||.|| ||.|| .||        ||.|
MLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82761.m00542.AA CRK7 5-286 34 3.5e-97 329.15 In-house 1-343 (343) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-343/343
Sequence Identity: 34% (118 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQE---EEGIPPTSVRENSILSELSHPNVVSVKEVI----------NTPFSLILIMEYLDKDLKNY
||...  |||||| ||||.|| |||. | | . .. |   .|| | |..||  || .| |.|.|  ||..          ..  |  .. || | ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LATQ-HGPINPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPM--RAYTKDVITLWYRAPEILLDAPAY--------
|       ...  .|..  |.| |. ||| ....||| |  |.|.|  | .|. ||||||.       | ||  |||||||.|| || .  |        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------DLSVDVWSVGCIIAEMMNRTPLFPGDSEIDQLYTIFKILGTPTESEWPGVSQFPNYSAEFPKW-----LK
                                ..|.||.||| .| ....|.|.|  |..|| .|.|| |.|.   || | . | . .  ||      | 
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

LDLSEKIQ--TNDQLALDLISKMLQYDPVKRITAKDALDHPYF
 . ... .    .. .|||  ||| .|| ||.||...|.|..|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 82761.m00542.AA CDK4 5-286 40 2.7e-96 326.22 In-house 1-290 (290) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-290/290
Sequence Identity: 40% (122 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEE--GIPPTSVRENSILSELS---HPNVVSVKEVINT------PFSLILIMEYLDKDLKNYLA
|. .  .||| || ||.||   || . | | .    .||  |.|   .|| |..  |    |||.|. ..|  .         . ...|  | ||. || 
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

TQHGP-INPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLPMRAYTKDVITLWYRAPEILLDAPAYDLSVDVWSVGCI
    | . |  ||    |.| |. . |   ||||| ||||.|... | .|| ||||||  |  | | |  |.||||||||.|| .. |   || ||||||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQM-ALTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCI

IAEMMNRTPLFPGDSEIDQLYTIFKILGTPTESEWP-----GVSQFPNYSAEFPKWLKLDLSEKIQTNDQLALDLISKMLQYDPVKRITAKDALDHPYF
.||| .| |||.| || |||  ||.. |.|.| .||       . || ...  .|    |..  .   .....||. ||| |.. ||..|  .| ||||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLPWDHFPQRHPRPFK----DFCPHM---CKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase 82761.m00542.AA Pkinase_Tyr 5-152 30 4.3e-16 55.11 Pfam 1-161 (270) Show / Hide 
Range on Protein: 5-152
Range on HMM: 1-161/270
Sequence Identity: 30% (51 aa)

YERLEKLGEGTYGAVYKARNK----TTGEILAMKVIHLEQEEEGIPPTS------VRENSILSEL-SHPNVVSVKEVIN-----TPFSLILIMEYLDK-D
 . ..||||| .| |||.. |     |.   | |..  |    |  .         || .|...| .|||.|.   |.         .....|||  . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGD

LKNYLATQ---HGPINPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPI
|..|| ..    .|...  . ....|| .|..| . ...||||    | |.......| ||||||| |
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 82761.m00542.AA TyrKc 5-286 23 1.2e-14 13.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-286
Range on HMM: 1-280/280
Sequence Identity: 23% (72 aa)

YERLEKLGEGTYGAVYKARNKTTGEILAMKVIHLEQEEEGIPPTSVRENSILSEL--SHPNVVSVKEVINTP-------FSLILIMEYLDK-DLKNYLAT
 . ..||||| .| |||.. |   .  | |... .  .| .     || .|...|  .|||.|    |. ..         | ..||| .. |||.||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDF----MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QHGPINPMLIKSYAYQILAGLSYCHCQGIIHRDMKPQNLLLNRGGFIKLCDFGLARPISLP---------MRA----YTKDVITLWYRAPEILLDAPAYD
 .. ...    |...|| .| .| | ...||||    | |..... .| .||||.| |             |.     .|... .   ||| . .   . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

LSVDVWSVGCIIAEMMNRTPLFPGD--------SEIDQLYTIFKILGTPTESEWPGVSQFPNYSAEFPKWLKLDLSEKIQTNDQLALDLISKMLQYDPVK
   |||| |  . |.. .    . .        .|. ..    . .  | . . | .|                 .      | .   ....  ..|| .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS-----------------F--VCCPDEMYQ-IMKQCWHEDPED

RITAKDALDHPYF
| | ..   | .|
RPTFSEI--HECF