Gene 85788.m00111 (T.vaginalis)
85788.m00111
Species: T.vaginalis
Alias: 85788.m00111, TvagK0958
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 85788.m00111.AA | Protein | None | 1411 | None | Fasta, JSON |
| 85788.m00111.kin_dom | Protein Kinase Domain | None | 257 | None | Fasta, JSON |
Protein domains of 85788.m00111.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PI3Kc | 85788.m00111.AA | PI3Kc | 1153-1407 | 25 | 4.3e-77 | 263.36 | SMART | 1-336 (336) | Show / Hide |
Range on Protein: 1153-1407
Range on HMM: 1-336/336
Sequence Identity: 25% (87 aa)
GCIFKIQDDVRTDCLMIQLIDKFGVICRES----GLDIYVCPYKVFSTGFDRGVIEVIQHAKSRHDIGMTY-----------------------------
. ||| || | |..|.|.. . | .. ..| ...|||. .|| . |.||.. .....| | ..|
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM
----------------------------------KSELLHYFTTKFGPIGTPKFNAAQDNFIKSLASYSLICYLFQVKDRHNANIMID-DEGHIIHIDFG
. |...|. .|. . ....|.|||..|.| |. ..|.....|||| |||.| ..||..|||||
MIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPN-EDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG
FIFDISPGGNIKF-----ERAPFKLTREYVNVLGG-STDAVPFQRFVTLFMRCFLAVQSRYIEIINIVELMKSAGL-PCFTKN--SIKSLKERFALT-KN
.||. . ....| ||.||.||...|.| || .. |..|.|. .| ..|. . .|.|..|.| .... ||.... .|| |..|| | ..
HIFGHG-PKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMMEKDIKYLRQRFRLDHLS
ASELPDYIKG-----LVTSSLDSFYTSAYDSFQNSQNN
| |.. | .|..|..| .|..|.| ...
DEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
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| PI3_PI4_kinase | 85788.m00111.AA | PI3_PI4_kinase | 1151-1359 | 21 | 1.2e-42 | 152.82 | Pfam | 1-300 (300) | Show / Hide |
Range on Protein: 1151-1359
Range on HMM: 1-300/300
Sequence Identity: 21% (66 aa)
PYGCIFKIQDDVR--TDCLMIQLI-----------------------DKFGVICRESGLDIY----VCPYKVFSTGFDRGVIEVIQHAKSRHDIGMTY--
|. ||| || | |..|.|.| . ... |.| . ||.. .|| ..|.||.. .. . | | ||
WYPFIFKGGDDLRCRQDMRMMQMICVFKPKDEEPYANNPNKWTMWQHRLMNKCWKKDGCDRRRNMQMQPYRCIPTGPWCGMIEWVPNCTTFHEIPRTYMV
-----------------------------------------KSELLHYFTTKFGPIGTPKFNAAQDNFIKSLASYSLICYLFQVKDRHNANIMI---DDE
| |...|. ... . . .| |||..|.| .. . |.... |||| |||. ..
KCKHKHFNKEHKMWMKMWPDWWHLMRMQKVEVFEMRIMKTPKPGLYQWFWKHNPDA-YEEWWEARDNFVRSCAGMCVVDYILGNGDRHNDNIMVKDDKTT
GHIIHIDFGFIFD-ISPGGNIKFERAPFKLTR------EYVNVLGGS---TDAVPFQRFVTLFMRCFLAVQSRYIEIINIV-------ELMKSAGLPCFT
||..|||||..|. . .|.|| ||..|. ..|...|| . ...| .. .. ..|. . ..| |.| .|||...
GHLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRALRRHMNLCMNLLKKAVMRGECMVHDGLPMWR
K
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S
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| Kinase | 85788.m00111.AA | ATR | 1241-1346 | 25 | 5.4e-14 | 43.64 | In-house | 162-267 (267) | Show / Hide |
Range on Protein: 1241-1346 Range on HMM: 162-267/267 Sequence Identity: 25% (27 aa) AAQDNFIKSLASYSLICYLFQVKDRHNANIMIDD-EGHIIHIDFGFIFDISPGGNIKFERAPFKLTREYVNVLGGSTDAVPFQRFVTLFMRCFLAVQSRY ....|...| |..... |. ||| ||.|| | ..|.|. || .. | ||.||. |. .| | | . |.|. . SSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVP-EIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDHRDDI IEIINIV . ... MSVWDCF |
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| Kinase | 85788.m00111.AA | FRAP | 1245-1310 | 41 | 3.3e-10 | 33.85 | In-house | 139-205 (251) | Show / Hide |
Range on Protein: 1245-1310 Range on HMM: 139-205/251 Sequence Identity: 41% (28 aa) NFIKSLASYSLICYLFQVKDRHNANIMID-DEGHIIHIDFGFIFDISPGGNIKFERAPFKLTREYVN |. .||| |.. |. ||| |||.. | |.||||| |.. |. ||.||| || NYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFGDCFEVAMRREKFPEKIPFRLTRMLVN |
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| Kinase | 85788.m00111.AA | PIKK | 1245-1313 | 42 | 8e-07 | 21.27 | In-house | 188-257 (290) | Show / Hide |
Range on Protein: 1245-1313 Range on HMM: 188-257/290 Sequence Identity: 42% (30 aa) NFIKSLASYSLICYLFQVKDRHNANIMIDDE-GHIIHIDFGFIFDISPGGNIKF-ERAPFKLTREYVNVLG |.. |.|. . | ||| ||||| . | |.|||||..| | .. .. | || ||| || .| NYTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFE-SAMQRLPVPEKVPFRLTRNMVNAMG |
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| Kinase | 85788.m00111.AA | ATM | 1246-1313 | 35 | 1.5e-05 | 13.28 | In-house | 140-207 (304) | Show / Hide |
Range on Protein: 1246-1313 Range on HMM: 140-207/304 Sequence Identity: 35% (25 aa) FIKSLASYSLICYLFQVKDRHNANIMIDDEG-HIIHIDFGFIFDISPGGNI--KFERAPFKLTREYVNVLG . .| | |.. |. . ||| ||.| . ..||| | |. | | | ||.|||. | .| YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQ---GKILPTPETVPFRLTRDIVDGMG |
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| Kinase | 85788.m00111.AA | DNAPK | 1251-1310 | 35 | 0.000598 | 10.05 | In-house | 192-255 (301) | Show / Hide |
Range on Protein: 1251-1310 Range on HMM: 192-255/301 Sequence Identity: 35% (23 aa) ASYSLICY---LFQVKDRHNANIMID-DEGHIIHIDFGFIFDISPGGNIKFERAPFKLTREYVN ..| .|| . ||| | |. . | || ||||. | . | || ||| ..| RNYAVICISHWILGIGDRHLNNFMVNMENGDIISIDFGHSFGSATQFLPVPELMPFRLTRCFIN |
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