87054.m00094

Species: T.vaginalis
Alias: 87054.m00094, TvagK0058
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
87054.m00094.AA Protein None 394 None Fasta, JSON
87054.m00094.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 87054.m00094.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87054.m00094.AA CAMK 19-267 24 4.90000000001e-113 365.7 In-house 1-425 (425) Show / Hide
Range on Protein: 19-267
Range on HMM: 1-425/425
Sequence Identity: 24% (106 aa)

EIGYGAFSIVKLVQHSQSN------------NFFACKVISKEKLSS-------------------------IKRIERFEDEIRIQQQ-------LHHPNV
..| |.|..|||..| ...              .|.|.|.|.||..                          |  .... ||.| ..       |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQIYDLLKD-------------------EKNFYIMM---EFCQGGEL----FQYIVDK---------------GKLTEDEAKQILDQILEGIKYIHKMGV
...|.   |                   .|..|. |   |.|.||||    |.|||..               |..||.||...  ||.....|.|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKPENILIDQN-----------------GNVKLSDFGLSKYVSLKSN-----------------------LVKTPCGSPCYAS-PECLSG------
||||.||||||.|.|                 .|.|..|||.....  ..|                       . ||.||.|.|.. || |.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------LPYNGYISDMWSVGVLLYACVCGQLPWTKR-------------SQAELFAQVKSGSYE-IPSSLSL-----------------------ECQD
        || |. .||||.||.||...|| .|.                .. ||| ....| |. .|. .|                        ||.|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIMRLMDTDTNTRITPEEALKHEWF
|| ... .| . |.| |..|.|.|.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 87054.m00094.AA AMPK 14-267 41 2.3e-110 328.84 In-house 1-254 (254) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-254/254
Sequence Identity: 41% (105 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFACKVISKEKLSSIKRIERFEDEIRIQQQLHHPNVVQIYDLL-KDEKNFYIMMEFCQGGELFQYIVDKGKLTED
|  .  || |.|  ||.  | . ..  | |.. |.|. . .  || . ||.| . . ||...| |. . . .. ... ||. .||||| ||| .|.|.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNGNVKLSDFGLSKYVSLKSNLVKTPCGSPCYASPECLSGLPYNGYISDMWSVGVLLYACVCGQLP
||.  . ||. |. |.|. ..|||| ||||.|.|.| |.|. |||||.. . . .. || |||||||.||  || .|.|   | || || ||| .|| ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMK-DGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

WTKRSQAELFAQVKSGSYEIPSSLSLECQDLIMRLMDTDTNTRITPEEALKHEWF
    ....|.. .|.| |.||. || |..|||...  .| . ||| ..  .|.||
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 87054.m00094.AA CAMKL 14-267 33 6.30000000001e-108 345.54 In-house 1-297 (297) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-297/297
Sequence Identity: 33% (103 aa)

YHFKGEIGYGAFSIVKLVQH-SQSNNFFACKVISKEKLS--SIKR-------------IERFEDEIRIQQQLH---HPNVVQIYDLLKDEKN------FY
| .  ..| |.|. ||| .| .  .   | |.| |.|..   ...             |.|   ||.|...|.   |||....|. . ....      .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRR---EIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIY

IMMEFCQGGE--LFQYIVDK----GKLTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNG--NVKLSDFGLSKYVS-L---KSNLVKTPCGSP
. || |.|||  ||.||| .    |...|.||...  ||.....|.|..|.|||||||||||.|.||  |.|..|||.| .       . .. || ||||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

CYASPECLSG--LPYNGYISDMWSVGVLLYACVCGQLPWTKR--------SQAELFAQVKSGSYEIP--SSLSLECQDLIMRLMDTDTNTRITPEEALKH
.|..|| ..|   ||.|.  |.|| ||.||| |||.||.            . .|. ....| |..|  ...| .|.||| ... .. . |.| .. ..|
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

EWF
.|.
PWM

Kinase 87054.m00094.AA MARK 14-267 39 1.4e-99 326.15 In-house 1-262 (262) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-262/262
Sequence Identity: 39% (103 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFACKVISKEKLSSIKRIERFEDEIRIQQQLHHPNVVQIYDLLK--DEKN-FYIMMEFCQGGELFQYIVDK--GK
| .. .|| |... |||..|  ..  .| |.. |.||.  . .. .. ||.| ..|.|||... ..     .|.. .|. || . ||||..||. .  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNG--NVKLSDFGLSKYVSLKSNLVKTPCGSPCYASPECLSGLPYNGYISDMWSVGVLLYAC
|.|.||..|  ||.....| |....|||||||||||||.||  |.|..|||.|  .   . | .| ||.| |..|| ... ||.|.  |.|| ||.||. 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKL-NTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VCGQLPWTKRS--QAELFAQVKSGSYEIPSSLSLECQDLIMRLMDTDTNTRITPEEALKHEWF
|||..|.   .  . ||. .. .|.|.||. .| ||..|| ||. .. . |.| || .||.|.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 87054.m00094.AA S_TKc 14-267 32 3.2e-98 333.51 SMART 1-231 (231) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFACKVISKEKLSSIKRIERFEDEIRIQQQLHHPNVVQIYDLLKDEKNFYIMMEFCQG--GELFQYIVDKGK---
|..  .|| |||. |....|  ..  .|.|.|.          |... ||.| .. ||||.|..||   | ...|. ||.| |  |.||.||...|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNGNVKLSDFGLSKYVSLKSNLVKTPCGSPCYASPECLSGLPYNGYISDMWSVGVLLYA
   ..| .|. .. ||.....|.|..|..|||.||||||.|.  ..|..||||.. .       .| ||.| | .|| |   .|..  .|.||.|..|| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

CVCGQLPWTKRSQAELFAQVKSGSYEIPSSLSLECQDLIMRLMDTDTNTRITPEEALK-------HEWF
..||. |.    ....| ...          | |. |.|..... | . |.|  |||.       |.||
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 87054.m00094.AA Pkinase 14-267 33 1.7e-90 311.73 Pfam 1-293 (293) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-293/293
Sequence Identity: 33% (99 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFACKVISKEKLSSIKRIERFE-DEIRIQQQLHHPNVVQIYDLLKDEKNFYIMMEFCQGG----ELFQYIV--DK
||... || |.|. |.. .|  ..  .|.|.|.|.. .| |.....   ||.| . |.|||.|..||   |... |. ||.|.||    .|| ||   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--TEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNGNV----KLSDFGLSKYV-SLKSNLVKTPCGSPCYASPECLSGLPYNGYISDMWSV
|..  .|.|.| .. |||.|..|.|.||..|||.||||||||.||..    |..||||.| .   ..   .|.||.| |..|| . | .| |. .||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYACVCGQLPWTKR------SQAELFAQVKSGSYEIPSSLS---------------------LECQDLIMRLMDTDTNTRITPEEALKHEWF
|..||  .||..|.  .      .| ......... .. ... .                      ||.|.| .. . | . |.|.|..|.|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 87054.m00094.AA Ciliate-E2 14-267 26 6.8e-90 304.96 In-house 1-365 (365) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-365/365
Sequence Identity: 26% (102 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFA-----------------------CKVISKEKLSSIKRIERFEDEIR----------IQQQLHHPNVVQIYDL
| |   || |.|..|..... . .. ||                        |...| .. .||....   ||.          |..|| |||....|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LK--DEKNFYIMMEFCQGGELFQYIV------------DKGKLTEDEAKQILDQILE---------------GIKYIHKMG-VVHRDIKPENILIDQNGN
 .  |..|.|. ||.||||.||.||             | ...|| |.|.|  |||.               ...|.|. . ..||||||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLSDFGLSKYVS-------------------------------LKSNLVKTPCGSPCYASPECLSGLPYNG--------YISDMWSVGVLLYACVCGQL
.|..||||||...                               .. |...| ||.| | .|| |.| .|..        | .|.||.||.|| ...|..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWTKRSQAELFAQVKSGSYEIP------------------SSLSLECQDLIMR----LMDTDTNTRIT-PEEALKHEWF
|.        . | | . ...|                   ..|.||.||| .    ... | . ||| .|..|.|.||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 87054.m00094.AA ULK 14-267 30 1.4e-89 303.87 In-house 1-324 (324) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-324/324
Sequence Identity: 30% (100 aa)

YHFKGEIGYGAFS-IVKLVQHSQS---NNFFACKVISKEKLSSIKR-------IERFEDEIRIQQQLH---HPN--VVQIYDLLKDE--KNFYIMMEFCQ
|  . ..| |.|   |    . ..   | ..|||.|.| |.. .|        .. .. ||.|...|.   |||  .|. || ...   .|.||.||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGELFQYIVDKGK---------LTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNGN------------VKLSDFGLSKYVS---LKSNLVKT
|| |.|||  ..|         |.|.||.|.. ||..| |..||....||||||.||||  .              .|..|||..| |    .  .. .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

PC------GSPCYASPECLSGL----PYNGYISDMWSVGVLLYACVCGQLP---WTKRSQA----ELFAQ-------VKSGSYEIP-----SSLSLECQD
 .      |.| | .|. |.|.    ||. | .|.||.|...| .. |. |   | ...|     .|  .       .|    ..|       .| ||.|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIMRLMDTDTNTRITPEEALKHEWF
||.|..  | . ||. || ..|.||
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 87054.m00094.AA Ciliate-E2-Unclassified 14-267 26 1.8e-87 296.87 In-house 1-352 (352) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-352/352
Sequence Identity: 26% (93 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFF-----ACKVISKEKLSSIKRIERFEDEIRIQQQLH-------------------HPNVVQIYDLLKDEKNFYI
|..   || |.|..|...||.. . ..     ..|.... ...  . . ..  |. . ...                    ||..|  ..  .|..|.||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

MMEFCQGGELFQYIVDKGK-----------------LTEDEAK-----QILDQILEGIKYIHKMG-VVHRDIKPENILIDQNG---NVKLSDFGLSKYVS
 ||.|.||.|.||| ...|                 .|| .||     ... |||.|..|.|. . ..||||||||||.|.||   ..|..|||.||.  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

L---------------KSNLVKTPCGSPCYA----SPECLSGLPYNG---YISDMWSVGVLLYACVCGQLPWTKRSQAE----------------LFAQV
                |... .| ||.|.|     .||.| |  |..   | .|.||.||.||... |..|   ... .                |. . 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KSGSYEIPS--------SLSLECQDLIM----RLMDTDTNTRITPEEALKHEWF
| . ...|.         .| |..|.|     .... . | |||.|..|.| ||
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 87054.m00094.AA ULK 14-267 30 2e-86 293.4 In-house 1-329 (329) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-329/329
Sequence Identity: 30% (101 aa)

YHFKGEIGYGAFSIVKLVQHSQS----NNFFACKVISKEKLSSIKR-------IERFEDEIRIQQQLH--------HPNVVQIYDLLKDE--KNFYIMME
|. . ..| |.|  |    . ..    |  .|||.|.|.|.. ..        .. .. ||.|...|.        |||.|. || ...   .|.||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCQGGELFQYIVDKGK----------LTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQN------------GNVKLSDFGLSKYVSLK---SN
.|.|| |.|||  ..|          |.|.||.|.. |||.| |..||....||||||.||||. .            | .|..|||..| |.      .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LVKTPC------GSPCYASPECLSGL----PYNGYISDMWSVGVLLYACVCGQLP---WTKRSQA-----ELFAQ-------VKSGSYEIP-----SSLS
. .|        |.| | .|. |.|.    ||. | .|.||.|...| .. |. |   | ...|      .|. .       .|.   ..|       .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

LECQDLIMRLMDTDTNTRITPEEALKHEWF
 ||.||| |..  | . ||. || ..|.||
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 87054.m00094.AA QIK 14-267 34 1.3e-83 284.08 In-house 1-272 (272) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-272/272
Sequence Identity: 34% (95 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFACKVISKEKL--SSIKRIERFEDEIRIQQQLHHPNVVQIYDLLKDEKNFYIMMEFCQGGELFQYIVDKGK---
|     || | | .||| .|    .  | |.| |..|  . .....|   |. |  .| ||...  |. .  ..  || .|.|..||.| |.. .|.   
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYR---EVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGV

-----------------LTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNGNVKLSDFGLSKYVSLKSNLVKTPCGSPCYASPECLSGLPYNG
                 ..|.||...  ||. ...| || ..||||.| ||||.|.| |.|. |||.| . . .  | .| |||| || || . |  |.|
KMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNW-FKQGQLLMTWCGSPPYAAPEMFEGKEYDG

YISDMWSVGVLLYACVCGQLPWTKRSQAELFAQVKSGSYEIPSSLSLECQDLIMRLMDTDTNTRITPEEALKHEWF
  .| || ||.||. ||| ||    .  .| . | || . || ..|..|..|| . .  | . |.| .  ..| | 
PKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 87054.m00094.AA RSK 14-267 28 2.6e-78 266.45 In-house 1-278 (278) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-278/278
Sequence Identity: 28% (80 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFACKVISKEKLSSIKR-IERFEDEIRIQQQLH-HPNVVQIYDLLKDEKNFYIMMEFCQGGELFQYIVDKGK---
   .|..|||...... ..|....  .| ||..| |.   .. ...   |..| .    ||..|. ..  ..|. .|. ||.| |||||  .  ..    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQ---NGNVKLSDFGLSKYVSLK-SNLVKTPCGSPCYASPECLS---GLP-YNGYISDMWSVG
..||||.... .|   ....|. |..|||.|||||| |.   .| .||.|||..|. ... ... .|.|..  |. || |    .   . .   | || |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGH-DKACDWWSLG

VLLYACVCGQLPWTK---RSQAELFAQVKSGS--YEIP--SSLSLECQDLIMRLMDTDTNTRIT-----PEEALKHEWF
||.|    |..| .     ...|.......|    ..|  ..|| |..||| ...  | . |..      || ..|.||
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 87054.m00094.AA TyrKc 14-267 24 3.8e-17 54.57 SMART 1-280 (280) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YHFKGEIGYGAFSIVKLVQHSQSNNFFACKVISKEKLSSIKRIERFEDEIRIQQQL--HHPNVVQIYDLLKDE-------KNFYIMMEFCQGGELFQYIV
 ... ..| ||| .| . . .      | |.. ...      .| | .|.||  .|  ||||.|..|    ..       .  .| ||.. .| | .|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DKGK-LTEDEAKQILDQILEGIKYIHKMGVVHRDIKPENILIDQNGNVKLSDFGLSKYVSLK------SNLVKT----PCG--SPC-YASPECLSGLPYN
.... |. ..  ..  || .|  |.|.....|||.   |.|.. |. || ||||||...  .      .   ..     .    |    .|||.    ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GYISDMWSVGVLLY-ACVCGQLPWTK-----RSQAELFAQVKSGSYEIPSSL---------SLECQDLIMRLMDTDTNTRITPEEALKHEWF
   || || ||...  .  || |.        | .|....||.| .  .            . |  ... .  . | . | | .|   || |
TK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 87054.m00094.AA Pkinase_Tyr 43-174 30 4.8e-17 58.35 Pfam 34-174 (270) Show / Hide
Range on Protein: 43-174
Range on HMM: 34-174/270
Sequence Identity: 30% (44 aa)

KVISKEKLSSIK-RIERFEDEIRIQQQL-HHPNVVQIYDLLK-DEKN--FYIMMEFCQGGELFQYIVD----KGKLTEDEAKQILDQILEGIKYIHKMGV
|.. ||. ..    .| |  |..|  || ||||.|. |     ...    || ||....| |  |  .    |..||  .  |.  || .|  | . .. 
KML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNC

VHRDIKPENILIDQNGNVKLSDFGLSKYVSLKSNL-VKTPCG
.|||.   |.|.. |. || .||||....  ...  .|.  |
IHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG