93564.m00023

Species: T.vaginalis
Alias: 93564.m00023, TvagK0108
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93564.m00023.AA Protein None 467 None Fasta, JSON
93564.m00023.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 93564.m00023.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93564.m00023.AA CAMKL 8-256 33 5.1e-103 329.61 In-house 1-297 (297) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-297/297
Sequence Identity: 33% (99 aa)

YIFGQTIGEGSTGKVKIAVN-KNTNKTLAIKMVKKSIIANKPVVLSN-----------MKREIAIMRLLN---HPNLLHLESVFENNEY------IFLVE
|..|.|.|.|| |||| |.. ..|..  |||...|. | |.|....|            .|||.||..||   |||  .|  |.|. |.      |.|| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

QLAQYGS--LFDIVMS-------LNYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPE--TLAIADFGLACW-MP-----NNIASTYCGSPHYT
 ... |.  ||| . .       .  ..   .||||. ...|.|.. |.|||.|.||.|| .    .. |.|||.. . .|     ..  .| ||||.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVTYD--STYDGRIADIWSAGVILYMMLTKTTPFQGNSMQ---------ELIQNIRMANF-VPPNISPDADDLIYRILTPNPQNRITIKDIKIHPLF
|||.  .    |||. .||||.|||||.|.. . || . ...         ......   .. ... .| |. ||| ..|..||  |.||..|. || .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 93564.m00023.AA CAMK 13-256 22 2.2e-96 311.06 In-house 1-425 (425) Show / Hide
Range on Protein: 13-256
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)

TIGEGSTGKVKIAVNKNTN------------KTLAIKMVKKSIIAN------------------------KPVVLSNMKREIAIMRL-------LNHPNL
|.|.|| |||| ...|||.            .  |||...|. . .                        .|. . |..|||.||..       |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LHLESVFEN-------------------NEYIFLVE---QLAQYG----SLFDIVMS------------------LNYDQSIAFFRQIIYGLEYLHNKSI
..|  |.|.                   ......|     ... |     ||| . .                  .. ..   .||||. ...|.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKLENLLLIDPE-----------------TLAIADFGLACWMPNNI-------------------------ASTYCGSPHYTA-PEVTYD------
.|||||.||.|| | .                 .. |.|||.|. .. .                           .|.||.|.| | |||         
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------STYDGRIADIWSAGVILYMMLTKTTPFQGN-------------SMQELIQNIRMANF--VPPN-----------------------ISPDADD
        .|.|. .|.||.|||||.||. . ||.|              ...|| ..|. ...   ||                        .|... |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIYRILTPNPQNRITIKDIKIHPLF
|| ..|...|..|.||.... || .
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 93564.m00023.AA AMPK 8-256 41 2.4e-89 265.39 In-house 1-254 (254) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-254/254
Sequence Identity: 41% (107 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVKKSIIANKPVVLSNMKREIAIMRLLNHPNLLHLESVF-ENNEYIFLVEQLAQYGSLFDIVMS---LNY
|| |.|||||. ||||... . |..  |||   |  |... .| .  .||| |..|..||..  |  |  | .. ||.|   .. | ||| . .   |. 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVER-IQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

DQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPETLAIADFGLACWMP-NNIASTYCGSPHYTAPEVTYDSTYDGRIADIWSAGVILYMMLTKTTP
...  || ||| |.||.|.  | |||||.||||| .   . |.||||   |  ..  .| |||| | |||.     | |.  |||| ||||| ||  . |
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FQGNSMQELIQNIRMANF-VPPNISPDADDLIYRILTPNPQNRITIKDIKIHPLF
|   .  .| ..|.   . .| ..||.| ||| ..|...|..||||.||. || |
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 93564.m00023.AA S_TKc 8-256 32 5.1e-86 292.99 SMART 1-231 (231) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-231/231
Sequence Identity: 32% (86 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVKKSIIANKPVVLSNMKREIAIMRLLNHPNLLHLESVFENNEYIFLVEQLAQY--GSLFDIVMS-----
| ....||.|. |||. ...|.|..  |||..|            ...|||.|..  .|||. .|  ||.. .....|  ..    |.|||.  .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LNYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPETLAIADFGLACWMPNNIASTYCGSPHYTAPEVTYDSTYDGRIADIWSAGVILYMM
    ..  .   ...||. .|||.|.. |.||||| ||.|| .  .. |.|||||. .     .|.||.|.| ||||     |... .|.|| |.||| |
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTKTTPFQGNSMQELIQNIRMANFVPPNISPDADDLIYRILTPNPQNRITIKDIKI-------HPLF
|.  .||.   ||.....|.         ||.| |.| ..|. .|..|.|. ..         || |
LCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 93564.m00023.AA Pkinase 8-256 31 2.4e-80 278.02 Pfam 1-293 (293) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVKKSIIANKPVVLSNMKR--EIAIMRLLNHPNLLHLESVFENNEYIFLVEQLAQYG----SLFDIVM--
| .|..||.|| |.|.....|.|.|. |.| .||.   .|. .. .  |  ||.||. ||||| . |  .||.. .| .|  ... |    .|||...  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

---SL--NYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPETL----AIADFGLAC---WMPNNIASTYCGSPHYTAPEVTYDSTYDGRIADIW
   ..   ... . ...||. ||||.|...|.|||||.||.|. .  ..     |.|||||.   . .|  ..|.||.|.| ||||  ...|.|. .|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SAGVILYMMLTKTTPFQGN------SMQELIQNIRM-----------------------ANFVPPNISPDADDLIYRILTPNPQNRITIKDIKIHPLF
|.|.||| ||.. .||.|       .....|..|..                       . .. .|.|... |.|...|...|. |.|...|. || |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 93564.m00023.AA BRSK 8-256 40 2.6e-78 266.42 In-house 1-254 (254) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-254/254
Sequence Identity: 40% (104 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVKKSIIANKPVVLSNMKREIAIMRLLNHPNLLHLESVFENNEYIFLVEQLAQYGSLFDIVMS---LNYD
|. . | | | ||.||. | . | |  ||| . |    ||. .|    ||||||.| .||. ...  |.||  | .|.    . | |||       |   
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

QSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPETLAIADFGLACWMPNN-IASTYCGSPHYTAPEVTYDSTYDGRIADIWSAGVILYMMLTKTTPF
    |||||| .|.. | ..||||||| ||||| .     |||||.|   ..  .  | ||||||  |||     |||| ||.||.||||| .|.   ||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

QGNSMQELIQNIRMANF-VPPNISPDADDLIYRILTPNPQNRITIKDIKIHPLF
  . . .|   ..   | .|. | ||. ||    .. .|. ||..|.|. || .
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY

Kinase 93564.m00023.AA MARK 8-256 37 7.9e-76 247.37 In-house 1-262 (262) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-262/262
Sequence Identity: 37% (99 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVKKSIIANKPVVLSNMKREIAIMRLLNHPNLLHLESVFE--NNEY-IFLVEQLAQYGSLFDIVMSL---
| ...|||.|| .||| |..|.|..  |||...|  . |.|  ..| .|||.||..|.|||   |  |.|  ...  |.|.  .|  |.|.| . .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKL-NDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

--NYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPE--TLAIADFGLA-CWMPNNIASTYCGSPHYTAPEVTYDSTYDGRIADIWSAGVILYMM
    .   ..||||.....|.|.|.|.|||.|.||.|. .       |.|||.. | .|..  .| ||.| | |||..    |||. .|||| ||.|| |
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LTKTTPFQGNS--MQELIQNIRMANFV-PPNISPDADDLIYRILTPNPQNRITIKDIKIHPLF
.. . || | .  . || ..|.  ..  |...|... .|| |.||.||  |.||..|  || .
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 93564.m00023.AA Ciliate-E2 8-256 26 3.4e-68 232.89 In-house 1-365 (365) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-365/365
Sequence Identity: 26% (98 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKM-------------VKKSIIANKPVV---LSNMKREIAIMR----------------LLNHPNLLHLESV
|.| . ||.|. |.|. . .....|  |||.             ||..|.| | .    . ..|.|| |||                .|||||.. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NNEYIFLVEQLAQYGSLFD-----IVMSLNY---------DQSIAFFRQIIY---------------GLEYLHNKS-ICHRDLKLENLLLIDPETL
|.  ....|.||  ..|.|.|||        ...           . . ...||..               .|||||.|  |.|||.|.||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

AIADFGLAC----------------WMPN-----------------NIASTYCGSPHYTAPEVTYDSTYDG--------RIADIWSAGVILYMMLTKTTP
 |.||||.                 |...                 |.. |.||.|.| |||.     ||.          .||||.|||||.||.. .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FQGNSMQELIQ-NIRMANF--------------VPPNISPDADDLIYR----ILTPNPQNRIT-IKDIKIHPLF
|    .|. .| .|.  ..               . ..|... ||| .    .|  .|..||| ...|. || |
F----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 93564.m00023.AA Ciliate-E2-Unclassified 8-256 24 3.6e-67 229.45 In-house 1-352 (352) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVKKSIIANKPVVLSN---MKREIAIMRL------------------LNHPNLLHLESVFENNEYIFLVE
|.....||.|. |||. ...|....  |.|. ||..| ..  ....   |  .......                  ..||...... .|.. ..|..| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

QLAQYGSLFDIVMS--------------------LNYDQSI-----AFFRQIIYGLEYLHNKS-ICHRDLKLENLLLIDPE---TLAIADFGLAC-----
.....|.|...  .                    .   |..      .|.||. |||||| |  |.|||.|.||.|. .      . |.|||..      
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------WMPNNIASTYCGSPHYT----APEVTYDSTYDGR---IADIWSAGVILYMMLTKTTPFQGNS------------------MQELIQNI
              ......| ||.| |     ||||     ||..    .|||| ||||| ||. . ||..|.                  ... ... 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

RMANFVP-------PNISPDADDLIY----RILTPNPQNRITIKDIKIHPLF
.  .| .        ..|| | |.|     ..|  || .|||...|. ||.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 93564.m00023.AA ULK 8-256 28 2.7e-65 223.24 In-house 1-324 (324) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-324/324
Sequence Identity: 28% (92 aa)

YIFGQTIGEGSTG-KVKIAVNKNT---NKTLAIKMVKKSIIANKPVV------LSNMKREIAIMRLLN---HPN--LLHLESVFENN--EYIFLVEQLAQ
|.  . .|.|| | ||  . ||.|   |.  |.||. |. . .|.        . . |.|| ||. |.   |||     |  .||.    .|...  . .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

YGSLFDIVM------------SLNYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPE------------TLAIADFGLACWMPN-----NIAST
 | |...               |. .. | ||.||. |. .||.. | |||.|..|.|. ..             .| |||||.|    |     ..  |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YC------GSPHYTAPEVTY----DSTYDGRIADIWSAGVILYMMLTKTTPFQGN--SMQ----ELIQN-------IRMANFVPP------NISPDADDL
..      |.| | ||..         |.   .|||| |.|.| ||.  .||...  . .    .||.|       |.  .. .|      .|||.  ||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

IYRILTPNPQNRITIKDIKIHPLF
|.| |. ..  ||.. .|  ||.|
IRRMLQYDEKDRISWEEIFNHPWF

Kinase 93564.m00023.AA GIN4 53-256 41 2.5e-63 200.97 In-house 80-293 (293) Show / Hide
Range on Protein: 53-256
Range on HMM: 80-293/293
Sequence Identity: 41% (89 aa)

NMKREIAIMRLLNHPNLLHLESVFENNEYIFLVEQLAQYGSLFDIVMS---LNYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPET-LAIADF
.. ||| ||.|..||| . |  |.|.|. ..||   |. | ||.....   |     | .||||| |. | |   ||||||| |||||      . ||||
GIEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADF

GLACW-MPNNIASTYCGSPHYTAPEVTYDSTYDGRIADIWSAGVILYMMLTKTTPFQGN--SMQELIQNIRMANF-VPPN--ISPDADDLIYRILTPNPQ
|.|   ..|..  | |||||| |||.     |.|  .|.|| ||||. .||   ||. .   ...|.  .   .. .| .  || .| ||| .||.  |.
GMAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPE

NRITIKDIKIHPLF
 ||...||  ||| 
KRIKTRDILKHPLI

Kinase 93564.m00023.AA ULK 8-256 26 1.6e-62 214.06 In-house 1-329 (329) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-329/329
Sequence Identity: 26% (89 aa)

YIFGQTIGEGSTGKVKIAVNKNT----NKTLAIKMVKKSIIANKPVV------LSNMKREIAIMRLLN--------HPNLLHLESVFENN--EYIFLVEQ
|.  . .|.|| |||  . ||.|    |.  |.||. |. . .|.        .   |.|| ||. |.        |||   |  .||.    .|...  
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LAQYGSLFDIVM-------------SLNYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPE------------TLAIADFGLACWMPNN-----
. . | |...                |. .. | ||.||. |. .|| . | |||.|..| |. ..             .| |||||.|  . |.     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

IASTYC------GSPHYTAPEVTY----DSTYDGRIADIWSAGVILYMMLTKTTPFQGNSMQELI-----QNIRM------------ANFVP----PNIS
.. |.       |.| | ||..         |.   .|||| |.|.| ||.  .||...  ....     ..|.              .| .    |.||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PDADDLIYRILTPNPQNRITIKDIKIHPLF
|.  |||.| |. ..  ||.. ..  ||.|
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 93564.m00023.AA TyrKc 8-256 25 1.1e-15 30.62 SMART 1-280 (280) Show / Hide
Range on Protein: 8-256
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVKKSIIANKPVVLSNMKREIAIMRLL--NHPNLLHLESVFENN-------EYIFLVEQLAQYGSLFDIV
  .|...|||  |.|  .. |    . |.||.|..        .  . ||. ||. |  .|||.. |  |           | ...|  .. .|.| |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

--MS--LNYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPETLAIADFGLACWMPNN-IA----STYC-----GSP-----HYTAPEVTYDSTY
      |. .. . |  ||  | |||| | . ||||   | |. .. |  |.||||.    .   .    ..|      |.        .|||.  ....
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DGRIADIWSAGVILYMMLTK-TTPFQG-----NSMQELIQNIRMANFV--PPN--------ISPDADDLIYRILTPNPQNRITIKDIKIHPLF
     |.|| || .. ..|   .|  |      | ||.|....  .    |||         ...  ... .    .| .| | ..|  | .|
TTK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 93564.m00023.AA Pkinase_Tyr 8-151 31 1.4e-15 53.39 Pfam 1-158 (270) Show / Hide
Range on Protein: 8-151
Range on HMM: 1-158/270
Sequence Identity: 31% (51 aa)

YIFGQTIGEGSTGKVKIAVNK----NTNKTLAIKMVKKSIIANKPV-VLSNMKREIAIMRLL-NHPNLLHLESVFE-NNEY--IFLVEQLAQYGSLFDIV
 .||...|||. |.|. .. |    ||. . |.||.|    | ..   .  . ||..||. | .|||.. |  |     |   |..|  ....|.| |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

MS-------LNYDQSIAFFRQIIYGLEYLHNKSICHRDLKLENLLLIDPETLAIADFGLA
 .       |.  . . . .||  |.|||..| . ||||   | |. .. .  |.|||||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase 93564.m00023.AA GIN4 8-46 40 2.8e-09 25.37 In-house 1-40 (293) Show / Hide
Range on Protein: 8-46
Range on HMM: 1-40/293
Sequence Identity: 40% (16 aa)

YIFGQTIGEGSTGKVKIAVNKNTNKTLAIKMVK-KSIIAN
.  |.|.| ||||||..| |..| .  |.|..  |.|  .
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKIFNH