Gene 96252.m00287 (T.vaginalis)

96252.m00287

Species: T.vaginalis
Alias: 96252.m00287, TvagK0254
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
96252.m00287.AA Protein None 339 None Fasta, JSON
96252.m00287.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 96252.m00287.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 96252.m00287.AA S_TKc 12-263 28 8e-74 252.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

YIFKKAIGKGGFSTVYLIESEEYHQQYVAKVTPIDDQPVKEGNVDPLDAEITALMSLSHQNIIRLYDHFTEGHNFFMILEYCQQ--GSLQDAVGEAG---
| . . ||||.|..||.    . ....  |. .           . .  ||  |..  | ||..|||.| . ....|..||| .  |.| |   . |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSLPQFITYARQILSALAFVHSKNIAHRDIKPGNILLDNSGHIKLSDFGISLRNANNVVSTFSGSLLYEPPEIVLKKPHNPMQADIWSLGVLFAFL
    ..  .   |..||..||.. ||..| |||.|| |||||.  |||..|||.. .      .|| |.. | .||..   ....  .|.||.|.... .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

INGCTPWHCDSINTLKTRICTATYKLKTNTPPEIVDIITRMIVVDPNERPTAQELLN-------EKIF
. |..|..   ....  .|.          .||  |.| .. ..||..|||| |.|.          |
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96252.m00287.AA CAMKL 12-263 28 1.4e-73 234.16 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YIFKKAIGKGGFSTVYLIESEEY-HQQYVAKVTP---IDDQPVKEGNVDP--------LDAEITALMSLS---HQNIIRLYDHFTEGHN------FFMIL
|.. | .|||.|..| | . . .  ...  |.     | . |... |  .        .  ||  ...|.   |.|||.||....   .      .....
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCQQGS--LQDAVGEAG-----LSLPQFITYARQILSALAFVHSKNIAHRDIKPGNILLDNSG--HIKLSDFGIS-----L-RNANNVVSTFSGSLLYE
|||. |.  |.| . . |     .. ..   | |||.||... ||..|.|||||| |||||..|   ||..||| |        . ..  .|| ||. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEIVLK--KPHNPMQADIWSLGVLFAFLINGCTPWHCDSI--------NTLKTRICTATYK-LKTNTPPEIVDIITRMIVVDPNERPTAQELLNEKIF
.|||...  ||..  ..||||.||.  ... |  |. .|..        . ..  .|. .|       . .  |.| .| .|.|..|||.....| . .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 96252.m00287.AA CAMK 17-259 19 8.3e-70 223.88 In-house 1-421 (425) Show / Hide 
Range on Protein: 17-259
Range on HMM: 1-421/425
Sequence Identity: 19% (82 aa)

AIGKGGFSTVYLIESEEYH------------QQYVAKVTPIDDQPV------------------------KEGNVDPLDAEITALMSLS-------HQNI
 .|.|.|..|.| .  .              |.. .|. . .  .                         .. . . .  ||  ...|.       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYDHFTEGHN-------------------FFMIL---EYCQQG----SLQDAVGEAG----------------LSLPQFITYARQILSALAFVHSKNI
|.||...  .|.                   ..|..   |||. |     | | . | |                ..  .  .| |||.||... ||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDIKPGNILLDNS-----------------GHIKLSDFGIS--LRNA-----------------------NNVVSTFSGSLLYEP-PEIVLK------
.|||.|| |||||..                 . ||..||| .  ..                         .   .|| |.. | . ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KPHNPMQADIWSLGVLFAFLINGCTPWHCD-------------SINTLKTRICTATYK-LKTNTPP-----------------------EIVD
       ||  . ..|.||.||.  ..  |. |.  |             ... |. .|... |       .|                       |  |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IITRMIVVDPNERPTAQELLN
 | .| .|||..|.|... ||
LIRKMLQVDPEKRMTIEQCLN
Kinase 96252.m00287.AA Pkinase 12-263 26 1.6e-60 212.15 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-293/293
Sequence Identity: 26% (80 aa)

YIFKKAIGKGGFSTVYLIESEEYHQQYVAKVTPIDDQPVKE------GNVDPLDAEITALMSLSHQNIIRLYDHFTEGHNFFMILEYCQQG----SLQDA
| ... ||.|.|..||.     . .... |. . ...  ..             .||  . .|.| ||.|||| |... .  |..|||. |    .| | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

VG---EAGL--SLPQFITYARQILSALAFVHSKNIAHRDIKPGNILLDNSGHI----KLSDFGISLR--NANNVVSTFSGSLLYEPPEIVLKKPHNPMQA
.    . ..  |  . . |..|||..|.. ||..| |||.|| |||.|| |||    |..|||..    . ||. .|| |.. | .||.... .. .  .
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKV

DIWSLGVLFAFLINGCTPWHCD----SINTLKTRICTATY-------------------------KLKTNTPPEIVDIITRMIVVDPNERPTAQELLNEK
|.||.|.... ...| .|.  .    . .. . .||   .                         .. .|...|  |.|.... .||..||||...|. .
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

IF
 |
WF
Kinase 96252.m00287.AA AGC 12-263 20 1.9e-60 153.98 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-395/395
Sequence Identity: 20% (81 aa)

YIFKKAIGKGGFSTVYLIESE------EYHQQYVAKVTPIDD-QPVKEGN-VDPLDAE------------ITALMSLS----------HQNIIR-LYDHF
. |.| ||||.|..||| .           ..|  ||   ..    |. | |.   .|               |. ..          |..|.. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TEGHN--FFMILEYCQ----------Q-GSLQDAV---GEAGLSLPQFITYARQ-------ILSALAFVHS-KNIAHRD-IKPGNILLDNSGHIKLSDFG
    .   ....||..             ...      .|  .. ..   || .       |..|| . || ..| ||| .|| |||||. |||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

ISLRNAN----------------------------------------------------NVVSTFSG--SLLYEPPEIVLKKPHNPMQADIWS--LGVLF
 . .. |                                                    .  .|| |  .  | .|||.    ...  .|.||  ||.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

AFLINGCTPWHCDS----------INTLKTRIC------TATYKLK----------TNTPPEIVDIITRMIVVDPNERPT----------AQELLNEKIF
  .. |..| . |.           . .  .|.      .   |.            .  || .|.|......||..|..          |.|. | . |
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 96252.m00287.AA Ciliate-E2-Unclassified 12-263 23 1.1e-59 204.63 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-352/352
Sequence Identity: 23% (83 aa)

YIFKKAIGKGGFSTVYLIESEEYHQQYVAKVTPIDDQPVKEGNVDPLD---AEITALMSLS-------------------HQNIIRLYDHFTEGHNFFMI
|.. | ||.|||..||. . ..   || |. . .. | .|  ..   |    |........                   | .|......|.   |....
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYCQQGSLQDAVGE------------------AGLSLPQFI-----TYARQILSALAFVHSKN-IAHRDIKPGNILLDNSG---HIKLSDFGISL----
.|||..|.|..   .                    ..  | .     .|..|||..| . |.|| | |||||| |||.||.|   .||..|||||     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------RNANNVVSTFSGSLLYE----PPEIVLKKPHNPM---QADIWSLGVLFAFLINGCTPWHCDSINT----------------LKTRIC
             .. ..  .||.|.. |     .||.  .. .. .   ..|||||||.. ... |  |  . . .                 |.  |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TATYKLKT--------NTPPEIVDIIT----RMIVVDPNERPTAQELLNEKIF
   .. .         . .||  |.|.    .|....||.|.|....||  .|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 96252.m00287.AA ULK 12-263 26 1.5e-57 197.47 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

YIFKKAIGKGGFSTVYLIESEEYH---QQYVAKVTPIDDQPVKEGNVDP--------LDAEITALMSLS--------HQNIIRLYDHFTEG--HNFFMIL
|. .. .||| | .||  . .. .   ...||    || |  .. | .         |. ||  .  |         |.||..||| | .    |...|.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKM-IDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

EYCQQGSLQDAVGEAG-----------LSLPQFITYARQILSALAFVHSKNIAHRDIKPGNILLDNS------------GHIKLSDFGISLRNANN----
|||..| |..   . .           || .. | . .|||... . |..|| |||||| |||..|             |..|..||| .    |.    
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

-VVSTFS------GSLLYEPPEIVL----KKPHNPMQADIWSLGVLFAFLINGCTP---WHCDSIN-----TLKTR-------ICTATYKLK-----TNT
 .  |..      |. ||  |.|.     .||..   .||||||..|  .. | .|   |   . .      |.         |..   . .      . 
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

PPEIVDIITRMIVVDPNERPTAQELLNEKIF
 ||. |.| ||...|...| . .||.| ..|
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 96252.m00287.AA ULK 12-263 25 1.6e-57 197.44 In-house 1-324 (324) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-324/324
Sequence Identity: 25% (82 aa)

YIFKKAIGKGGFS-TVYLIESEEYH---QQYVAKVTP---IDDQPVK---EGNVDPLDAEITALMSLS---HQN--IIRLYDHFTEG--HNFFMILEYCQ
|. .. .||| |  .||  . .. .   |.. .|. .   . ... .   .   . |. ||  .  |    |.|  |..||| | .    |...|.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

QGSLQDAVGEAG----------LSLPQFITYARQILSALAFVHSKNIAHRDIKPGNILLDN------------SGHIKLSDFGISLR-NAN----NVVST
.| |..   . .          || .. | . .||.... . |..|| |||||| |||. |            .|..|..||| .   . |    ..  |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FS------GSLLYEPPEIVL----KKPHNPMQADIWSLGVLFAFLINGCTP---WHCDSIN----TLKTR-------ICTATYKLK---TNTP--PEIVD
.       |. ||  |.|.     .||..   .||||||..|  .. | .|   |   . .     |.         |..   . .    . .  ||. |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IITRMIVVDPNERPTAQELLNEKIF
.| ||...|...| . .|..| ..|
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 96252.m00287.AA Ciliate-E2 12-263 21 1.5e-56 192.64 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

YIFKKAIGKGGFSTVYLIES----------------------EEYHQQYVAKVTPIDDQPVKEGNVDPLDAEIT----------ALMSLSHQNIIRLYDH
|.| | ||.|.|..||. .                       |.. ....|. . . .|     ... .  ||            | .|.| |||..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FT--EGHNFFMILEYCQQGSLQDAVG------------------EAGLSLPQFIT---------YARQILSALAFVHSKN-IAHRDIKPGNILLDNSGHI
|     .|.....||||.|.|.|                     .  . . . |.         |...|..|| . |||| | |||||| |||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFGISLRNAN---------------------------------NVVSTFSGSLLYEPPEIVLKKP--------HNPMQADIWSLGVLFAFLINGCTP
|..|||.| .. .                                 |.. |. |.. | .|||. .|.        .   ..|||||||.. ... | .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WHCDSINTLKTRICTATYKLKTN--------------------------TPPEIVDIITR----MIVVDPNERPT-AQELLNEKIF
.                .. . .                           ..|  |.| .    |...||..|.| ....|| ..|
F----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 96252.m00287.AA STE 12-263 21 3.8e-51 176.24 In-house 1-359 (359) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-359/359
Sequence Identity: 21% (78 aa)

YIFKKAIGKGGFSTVYLI---------ESEEY------HQQYVAKVTPIDDQPVKEGN--------------VDPLDAEITALMSLS--HQNIIRLYDHF
. . . ||||.| |||.          .. |       .. .  |. .....  |. .              .. .  ||  .. ..  |.||.. |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

TEG-------HNFFMILEYCQQGSLQDAVG---EAGLS------------LPQFITYARQILSA-LAFVHSKNIAHRDIKPGNILLDNSGHIKLSDFGIS
  .       .. ....||.  ||| | .    . | .             .| ....|||| . |.. ||..| ||||||.||||     .||.|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

LRNANN------------------VVSTFSGSLLYEPPEIVLKKPHNPM------QADIWSLGVLFAFLINGCTPWHCDSINTLKTRIC-----------
 . ...                     || |.  .  ||....  ..        ..|||||| .   ...|. |||  .      .|            
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----TATYKLKTNTP-------------------PEIVDIITRMIVVDPNERPTAQELLN--EKIF
         .|....                    ||  | | .  . |||.||||..||.   . .
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 96252.m00287.AA MARK 117-263 40 5.3e-46 148.46 In-house 111-262 (262) Show / Hide 
Range on Protein: 117-263
Range on HMM: 111-262/262
Sequence Identity: 40% (62 aa)

RQILSALAFVHSKNIAHRDIKPGNILLDNSG--HIKLSDFGISLRNANNV-VSTFSGSLLYEPPEIVLKKPHNPMQADIWSLGVLFAFLINGCTPWHCDS
|||.||. . |||||.|||||| |||.|  |   ||..||| | .  ..   .|| |.. | .|||.|||| .   .|||||||.  |.. |. |.  |.
RQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDT

--INTLKTRICTATYKLKTNTPPEIVDIITRMIVVDPNERPTAQELLNEKIF
  ...|. .| .  |.  .. ..|. ..| |...|.|.||||..|... . .
QDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 96252.m00287.AA MELK 12-263 31 7.6e-44 147.54 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-254/254
Sequence Identity: 31% (81 aa)

YIFKKAIGKGGFSTVYLIESEEYHQQYVAKVTPIDDQPVKEGNVDPLDAEITALMSLSHQNIIRLYDHFTEGHNFFMILEYCQQGSLQD-AVGEAGLSLP
|   . || |||. | |       |.   |.  .| . . . ..  . .|. || .|.||.| .||      . .||..|||  | . |  . .  |.  
YEVHDEIGTGGFAKVKLACHILTNQMVAIKI--MDKNQLGH-DLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEE

QFITYARQILSALAFVHSKNIAHRDIKPGNILLDNSGHIKLSDFGISLRNANNV----VSTFSGSLLYEPPEIVLKKPHNPMQADIWSLGVLFAFLINGC
.   . |||.||.|.|||.  ||||.|| |.|.|.  |.|| |||.  .   ..    . |  ||. |  ||..  |      ||.||.|.|   |. | 
ETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGF

TPWHCDSINTLKTRICTATYKLKTNTPPEIVDIITRMIVVDPNERPTAQELLNEKIF
 |.  | .  .  .|    |.      ||  ... .|. |||. |   ..|||    
LPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 96252.m00287.AA TyrKc 12-263 20 2.3e-14 9.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YIFKKAIGKGGFSTVYLIESEEYHQQYVAKVTPIDDQPVKEGNVDPLDAEITALMSL--SHQNIIRLYDHFTEG-------HNFFMILEYCQQGSLQDAV
  ..| .| | | .||. .     .|   |.   |        .  .  |.  ...|  .|.||.|||   |..       .  ....||.  |.|.|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

GEAG--LSLPQFITYARQILSALAFVHSKNIAHRDIKPGNILLDNSGHIKLSDFGISLRNANN--------VVSTFSGSLLYE-------PPEIVLKKPH
 . .  |...... .. || .  .. ||||. |||.   |.|... ...| |||| |    .         . .. ...           .||       
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

NPMQA------DIWSLGVL----FAFLINGCTPWHC-----DSINTLKTRICTATYKLKTNT---------PPEIVDIITRMIVVDPNERPTAQELLNEK
  .        |.|| ||.    | .   | .|.        |   .  .. .  .  .            |.|. .|...    ||..||| .|.   .
--NYGKFTTKSDVWSFGVCMWEIFTY---GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

IF
.|
CF
Kinase 96252.m00287.AA Pkinase_Tyr 61-157 28 1.2e-13 46.86 Pfam 53-158 (270) Show / Hide 
Range on Protein: 61-157
Range on HMM: 53-158/270
Sequence Identity: 28% (30 aa)

EITALMSL-SHQNIIRLYDHFT-EGHN--FFMILEYCQQGSLQDAVGEA-----GLSLPQFITYARQILSALAFVHSKNIAHRDIKPGNILLDNSGHIKL
|.  ...| .|.||.|||   | .|     ....||.. |.| |   .       |.... . ...|| ..... .|||. |||.   |.|.......| 
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKI

SDFGIS
.||| .
CDFGLA
Kinase 96252.m00287.AA MARK 12-100 25 4.8e-13 39.14 In-house 1-91 (262) Show / Hide 
Range on Protein: 12-100
Range on HMM: 1-91/262
Sequence Identity: 25% (24 aa)

YIFKKAIGKGGFSTVYLIESEEYHQQYVAKVTP---IDD-QPVKEGNVDPLDAEITALMSLSHQNIIRLYDHFT--EGHN-FFMILEYCQQGSLQD
| ..| ||.|....|.|  .  .....  |. .   ..| |     .  ..  ||  ...|.| |||.|.. .   .  . ...|.||.  |.| |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQ-----WMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYD