Gene 86997.m00193 (T.vaginalis)

86997.m00193

Species: T.vaginalis
Alias: 86997.m00193, TvagK0536
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
86997.m00193.AA Protein None 338 None Fasta, JSON
86997.m00193.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 86997.m00193.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 86997.m00193.AA S_TKc 22-270 27 2.5e-73 250.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

YIIDKELGSGGFATVYLAYHCKTGEKVAIKVIERETAADMGILTYVENELRITSRINHPNIVHVYDIVYAQEFIYIIMEYMEN--GDMQNFINNKFF---
| | ...|.|.|..||...| |||..||||.|             ...|..| .. .|||||. ||. .  ...|..|||...  ||.  .| ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKDMHARLIDFGFCREKSSNLKTVCGTQELMAPEIFLNKPYDGMKADIWAFGITIHLLAA
   ..  .  ... .|. || |.|..|| |||.||.||..|.  |  ..|||..|.     .|.||| . ||||..   .|.. |.|.|..|...  ...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

SCFPFEYKSDFQFLHDIKSNKLKIDIKPQGIIGWLVKNSLVYDPDERASAADMMS---------YI
 . ||.   ... .. |.         ..  .  .... |..||..| .| . .          ..
GYPPFP--QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86997.m00193.AA CAMKL 22-268 29 1.2e-72 231.13 In-house 1-293 (297) Show / Hide 
Range on Protein: 22-268
Range on HMM: 1-293/297
Sequence Identity: 29% (87 aa)

YIIDKELGSGGFATVYLAYHCKT-GEKVAIKVIERETAADMGILTY------------VENELRITSRIN---HPNIVHVYDIVYAQEF------IYIIM
|.| |.|| |.|..| || |..| |||||||.|... . .  . .             .. | .| ...|   ||||.. |.... .|.      ||..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYMENGD--MQNFINNKFF----LTQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKDM--HARLIDFGFCRE---K----SSNLKTVCGTQELM
|| ..|.  ....| ..      ..  .  |.   |. |. |.|..|| |||||| ||..|...   . .|||||. .   .       ||| ||. . |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIFLN--KPYDGMKADIWAFGITIHLLAASCFPFE-------YKSDFQFLHDIKSNKLKID-----I-KPQGIIGWLVKNSLVYDPDERASAADMMS
|||||.   ||||| |.|||. |..   .    .||.        |...  |. ..    . .     .   . .| ..    |. .|..|... . |.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKM----LQVNPEKRPTIHQIMN
Kinase 86997.m00193.AA CAMK 27-268 18 1.6e-71 229.5 In-house 1-421 (425) Show / Hide 
Range on Protein: 27-268
Range on HMM: 1-421/425
Sequence Identity: 18% (78 aa)

ELGSGGFATVYLAYHCKTG------------EKVAIKVIERETAAD-------------------------MGILTYVENELRITSR-------INHPNI
.||.|.|..|.|..| .|.            .|||||.|... . |                            .  |..|..| ..       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHVYDIVY--------AQEF------------IYIIM---EYMENG----DMQNFINNK---------------FFLTQQDQIRIAIEILGALIYLHERG
.. |..           . .            .|..|   ||...|    |. ..|  .               . .| ..  |.   |. |. |.|...
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ISHRDIKPANIMFDKDM-----------------HARLIDFGFCREKSSN--------------------------LKTVCGTQELMA-PEIFLN-----
| |||.|| ||..|...                    .||||| ... ..                          .||.||| | || ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KPYDGMKADIWAFGITIHLLAASCFPFEYK-------------SDFQFLHDIKSNKLKIDIKPQGI------------------------IG
        |||.| |.|.|. |.    .   ..||. .             .| . .. |.. |   . ..  .                          
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

WLVKNSLVYDPDERASAADMMS
 |... |..||..|..... ..
DLIRKMLQVDPEKRMTIEQCLN
Pkinase 86997.m00193.AA Pkinase 22-270 27 5.3e-67 233.7 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

YIIDKELGSGGFATVYLAYHCKTGEKVAIKVIERETAADMGILTYVEN--ELRITSRINHPNIVHVYDIVYAQEFIYIIMEYMENG----DMQNFIN--N
| | . .|||.|..||...| .||..||.|.|...  .... . .  .  |..|  |.||||||  ||...    ||..|||.|.|    |   .|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KFFL--TQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKDMHA----RLIDFGFC----REKSSNLKTVCGTQELMAPEIFLN-KPYDGMKADIW
.  .  . .. .... .|| .| |.|..|| |||.||.||..|...|     ...|||..      ..| ..|.||| . ||||. ..  .|.| |.|.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV-IRGGQYYGPKVDMW

AFGITIHLLAASCFPFEYK------SDFQFLHDIKSNKLKIDIK-----------------------PQGIIGWLVKNSLVYDPDERASAADMMSY--I
..|.... ..   .||  .      .. | .  |.. .|. |.                        . ..   ..|. | .|| .| .|.. .    .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD--FIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86997.m00193.AA MARK 22-219 38 2.4e-62 202.64 In-house 1-207 (262) Show / Hide 
Range on Protein: 22-219
Range on HMM: 1-207/262
Sequence Identity: 38% (80 aa)

YIIDKELGSGGFATVYLAYHCKTGEKVAIKVIERETAADMGILTYVENELRITSRINHPNIVHVYDIVY--AQEF-IYIIMEYMENGDMQNFINNK--FF
| . |..| |..|.|.|| | .||.|||||..|..   |   .  |. |..| ....||||.  ....     .  ||.|||| ..|.. ..| ..    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKDM--HARLIDFGFCREK--SSNLKTVCGTQELMAPEIFLNKPYDGMKADIWAFGITIHLLA
|.  .  ||   |. |. |.|...| |||||| ||. |...   . .|||||...    . |.| ||| . ||||||| ||||| |.|||. |.    . 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

ASCFPFE
  .|||.
CGYFPFD
Kinase 86997.m00193.AA ULK 22-262 25 2.1e-58 200.35 In-house 1-319 (329) Show / Hide 
Range on Protein: 22-262
Range on HMM: 1-319/329
Sequence Identity: 25% (81 aa)

YIIDKELGSGGFATVYLAYHCKT----GEKVAIKVIERETAADMGILTY-------VENELRITSRIN--------HPNIVHVYDIVYAQEF--IYIIME
|.....||.| |..|| ... ||    .||||.|.|....      . .       ..|| .|  ...        |||||  ||. . . .  ||||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YMENGDMQNFIN----------NKFFLTQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKD------------MHARLIDFGFCREKSSN-----
| . || ...|.          .| .|..|  | . . || .. .||...| ||||||.||. ...            ... . ||||..  ...     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-LKTVC------GTQELMAPEIFL----NKPYDGMKADIWAFGITIHLLAASCFP---FEYKSDF-----QFLHD-------IKSNKLKID-----IKPQ
 ..|        ||   |||.|.     .|||.  |.||| .|. .. .     |     . ...     . . .       ||...|...     ..  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

GIIGWLVKNSLVYDPDERAS
  .  | .  |.||...| |
PECKDLIRRMLQYDEKDRIS
Kinase 86997.m00193.AA ULK 22-262 24 2.4e-55 190.21 In-house 1-314 (324) Show / Hide 
Range on Protein: 22-262
Range on HMM: 1-314/324
Sequence Identity: 24% (77 aa)

YIIDKELGSGGFA-TVYLAYHCKT---GEKVAIKVIE----RETAAD------MGILTYVENELRITSRINHPN--IVHVYDIVYAQ--EFIYIIMEYME
|.....||.| |. .|| ... ||   ...||.|.|.    ..   .      .  | .. .....  ...|||  ||  ||. . .   .||||||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDMQNFIN---------NKFFLTQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKD------------MHARLIDFGFCREKSSNL--KTVC--
 || ...|.         .| .|..|  | . . |. .. .||...| ||||||.||.  ..             .. . ||||..   .|   ...|  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTQELMAPEIFL----NKPYDGMKADIWAFGITIHLLAASCFP---FEYKSDF----QFLHD-------IKSNKLKID-----IKPQGIIGW
        ||   |||.|.     .|||.  |.||| .|. .. .     |     . ...    . ..        || ......     .|    .  
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LVKNSLVYDPDERAS
| .  |.||...| |
LIRRMLQYDEKDRIS
Kinase 86997.m00193.AA Ciliate-E2 22-265 22 8e-54 183.14 In-house 1-358 (365) Show / Hide 
Range on Protein: 22-265
Range on HMM: 1-358/365
Sequence Identity: 22% (83 aa)

YIIDKELGSGGFATVYLAYHCKTGEKVAIKVIERET--------AADMGI----------LTYVENELRITSRIN----------------HPNIVHVYD
|.. | .|.|.|..||.. . |.....|||.|.            ... |          . ....|..|  .||                ||||.  |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

IVY--AQEFIYIIMEYMENGDMQNFIN--NKFF---------LTQQDQIRIAIEILG---------------ALIYLHERG-ISHRDIKPANIMFDKDMH
  .   .. ||..||| . ||.. .|.  .|..         .| .  ..|  .||                || |||... | |||||| ||.|     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

ARLIDFGFCREKSSN----------------------------------LKTVCGTQELMAPEIFLNKPYDG--------MKADIWAFGITIHLLAASCF
  .||||.... . .                                   .|.||| . |||||. .|.||.         |.|||..|.... .    .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFEYKSDFQFLHDIKSNKLKIDIKP-------QGIIGW------------LVKN----SLVYDPDERAS-AAD
||        .  || .|.... .          ...|            | |.     |..||..| . . .
PF--------QQQIKQCKIDFPCPEWQKDTQCI-QCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ
Kinase 86997.m00193.AA STE 22-270 22 2.1e-52 180.39 In-house 1-359 (359) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-359/359
Sequence Identity: 22% (84 aa)

YIIDKELGSGGFATVYLAYHCK---------------TGEKVAIKVIE--RETAADMG-------------ILTYVENELRITSRIN--HPNIVHVYDIV
. . ...|.|.| |||.|.. |               ||| .|||...  .... |               ..  ...|..| .. |  |||||. |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

YAQ-------EFIYIIMEYMENGDMQNFINNKFFLTQ-------------QDQI-RIAIEILGA-LIYLHERGISHRDIKPANIMFDKDMHARLIDFGFC
.         . ..|.||||..|    .|..|.   .              .|| .|. .|| . | |||. .| |||||||||..     . |.|||.|
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

REKSS-------------------NLKTVCGTQELMAPEIFLN------KPYDGMKADIWAFGITIHLLAASCFPFEYKSDFQFLHDIKSNKLKID----
   ..                   . .|..||.  ||||. ..      |.||  |.||| .|.||  .|  . |.   .... .  |  |. . .    
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----IKPQGIIGW--------------------------LVKNSLVYDPDERASAADMMS----YI
      .|  .                              ... |..||..|..| ....     |
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 86997.m00193.AA Ciliate-E2-Unclassified 22-245 22 4.7e-52 178.84 In-house 1-317 (352) Show / Hide 
Range on Protein: 22-245
Range on HMM: 1-317/352
Sequence Identity: 22% (73 aa)

YIIDKELGSGGFATVYLAYHCKTGEKV-----AIKVIERETAADMGILTYVENELRITSRIN-----------------HPNIVHVYDIVYA--QEFIYI
|.| | .|.|||..||...| |.. ..     ..|....     |       ||. .  ...                 ||... |... .   .. |||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEYMENGDMQNFINNKFF-----------------LTQQDQI-----RIAIEILGALIYLHERG-ISHRDIKPANIMFDKDM---HARLIDFGFCRE--
.|||.|.||....|... .                 .| |  .     ... .|| .| |||. . | |||||| ||.||...   . ..||||....  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------KSSNLKTVCGTQELM----APEIFLNKPYDGM---KADIWAFGITIHLLAASCFPFEYKSDFQ----------------FLHDI
                |. ...|.||| . |    |||.. .. ||..   |.|||..|. .. .    .||..... |                .. .|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KSNKLKIDIKPQ----GII
| ......  |.     ..
KQKNIQFPKFPWQQIPKHW
Kinase 86997.m00193.AA QIK 22-223 32 2.4e-47 163.59 In-house 1-223 (272) Show / Hide 
Range on Protein: 22-223
Range on HMM: 1-223/272
Sequence Identity: 32% (72 aa)

YIIDKELGSGGFATVYLAYHCKTGEKVAIKVIERETAADMGILTYVENELRITSRINHPNIVHVYDIVYAQEFIYIIMEYMENGDMQNFINNKFF-----
| |.. .| | ||.| || |  | .|||||.| . .. |   |. .. |  |  ...||.|.  |..   .. .||..|| .||.|   ....       
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDK-SQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LTQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKDMHARLIDFGFC--REKSSNLKTVCGTQELMAPEIFLNKPYDGMKA
               .. ..  |.  .|. |  |.|.|.| |||.|  ||..|..|   ..||||    ..   |.| ||.    |||.|. | |||.|.
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWAFGITIHLLAASCFPFEYKSD
|||  |.    | .  .||  |..
DIWSMGVVLYVLVCGALPFDGKTL
Kinase 86997.m00193.AA TKL 28-270 18 2.9e-47 163.32 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-270
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)

LGSGGFATVYLAYHCK--------TGEKVAIKVIER------------------------ETAADMGILTYVENELRITSRINHPNIVHVYDIVYAQEF-
.|||||..|| ...          ||. ||.|.. .                        .    . .    |.|... ||..|||||. . .. . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IYIIMEYMENGDMQNFINNKFFLTQQDQIRIAIEILGALIYLHE--------RGISHRDIKPANIMFDKDMH--------------AR
            ..|.|||...|.  ....       .  .|.|..|  .. |||         ..| |||.|..||. |....              . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LIDFGFCREKSSN----------------------LKTVCGTQELMAPEIFLNKPYDG---------------MKADIWAFGITIHLLAASCFPFE-YKS
. |||..|..| .                      . |.|||   ||||.. .....                 |.|...||| .  ... | |.. |..
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

DF--------QFLHDIKSNKLKIDIK------------PQG--IIGWLVKNSLVYDPDERASAADMMSYI
.         ...  . ...|.  |.            |.    .  | .    .||..| |. . ....
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 86997.m00193.AA Pkinase_Tyr 22-146 29 1.3e-20 70.45 Pfam 1-137 (270) Show / Hide 
Range on Protein: 22-146
Range on HMM: 1-137/270
Sequence Identity: 29% (41 aa)

YIIDKELGSGGFATVYLAYHC----KTGEKVAIKVIERETAADMG-ILTYVENELRITSRI-NHPNIVHVYDIVY-AQEF--IYIIMEYMENGDMQNFIN
 ...|.||.| | .||...      .|. .||.|.. .|.| .   ..    .|..| . . .|||||  | ...  .|   |||.||||..||. ..  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----KFFLTQQDQIRIAIEILGALIYLHERGISHRDI
.    |  || .| . ....|  .. ||..... |||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 86997.m00193.AA TyrKc 22-270 20 7.3e-17 49.9 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YIIDKELGSGGFATVYLAYHCKTGEKVAIKVIERETAADMGILTYVENELRITSRI--NHPNIVHVYDIVYAQ-------EFIYIIMEYMENGDMQNFI-
   .|.||.| | .||..      ..||.|..  ..      .    .|.|| ...  .|||||  | ..  |       | ..|.||||..|| .... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NNKFFLTQQDQIRIAIEILGALIYLHERGISHRDIKPANIMFDKDMHARLIDFGFCREKSSN--------LKTV----CGTQEL----MAPEIFLNKPYD
...  |. .| . ... |     |||.... |||.   |.. ... ...  ||| .|.  .          ...    .|   |    |||| .  . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GMKADIWAFGITIHLLAASCFPFEY------KSDFQFLHDIKSN--KLKIDI--------KPQGIIGWLVKNSLVYDPDERASAADMMSYI
  | |.|.||...  .   . .  .      .|... ....|.     . .          |. .   . |    .||..| . ..  ...
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF