Gene 93040.m00043 (T.vaginalis)

93040.m00043

Species: T.vaginalis
Alias: TvagK0104, 93040.m00043
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93040.m00043.AA Protein None 352 None Fasta, JSON
93040.m00043.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 93040.m00043.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 93040.m00043.AA S_TKc 14-266 24 4.5e-73 250.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

YILDKFIAEGGFSEVWLGRHEESNTQVAIKVFYKRTMDSKIKLNDFKNEVHIHKQLLHPFLVRFYETLENCFYYYIIMEFLPG--KTLKQMIVDKSS---
| . . | .|.|..|...|| ... .||||.            .....|. |.|.  ||..|..|.. ..  ..|..||...|   .|...|... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IEDNTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDNNIRLIDFGISRPITNNTVQNDKQGTLYYFAPERFNEETVTT-KVDIWSFGVILYY
   .   . | .. | . |..|.|   ...| ||| .|. .|.  .| ..|||..| .      .   ||..| ||| .     .. |.|.||.|.||| 
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MFSKTLPFSGESPAETAQLIKNSEPCYLDEIPQDITDLIKSCLIKDPASRISMEQIKK-------IHWV
|..   ||.   .... ..|.          ...  |.|. || |||. |..  .. .         |.
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93040.m00043.AA CAMK 19-266 19 2.7e-67 215.64 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-266
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

FIAEGGFSEVWLGRHEESN------------TQVAIKVFYKRTMDSKI-------------------------KLNDFKNEVHIHKQ-------LLHPFL
 . .|.|..| |..| ...            ..||||.  |. ...|                          ..  ...|..|.|.       | || .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRFYETLE--------NCFY------------YYIIM---EFLPGK----TLKQMIVDKSS---------------IEDNTLRTWAVQFLMAIDYLHTIP
...||. |        |  |            .|..|   |. .|      | ..||....               ..    |..  | . |..|.|   
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

QVCHMDLKASNLIVDSD-----------------NNIRLIDFGISRPITN------------------------NTVQNDKQGTLYYFA-PERFN-----
 ..| |||  |. .|..                 ||| .|||| .. ..                         .   ..  ||..| | || .|     
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------EETVTTKVDIWSFGVILYYMFSKTLPFSGE-------------SPAETAQLIK----NSEPCYLDEIP--------------------QDI
         .. .. |.|.|| ||||| | . ..|| |.             .. |. . |.    . .| |...|.                    |. 
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

TDLIKSCLIKDPASRISMEQIKKIHWV
 |||...| .||  |.. ||...  |.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 93040.m00043.AA Pkinase 14-266 26 9e-67 232.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

YILDKFIAEGGFSEVWLGRHEESNTQVAIKVFYKRTMDSKIKLNDFK-NEVHIHKQLLHPFLVRFYETLENCFYYYIIMEFLPGK----TLKQMIV--DK
| . . | .|.|..|....|  .. .||.|.. ||. .|. . .... .|..|.| | ||. ||.|.. |.  ..|..||...|      |. .|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SSI--EDNTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDNNI----RLIDFGISRP--ITNNTVQNDKQGTLYYFAPERFN-EETVTTKVDIWS
 ..  ...... .. | | ...|.|    ..| ||| .|. .|....|    ...|||...   . ||.  ..  ||..| |||  .  .  ..|||.||
GCFYFSEWECKFYMYQILRGLEYCHSM-GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGVILYYMFSKTLPFSGE----SPAETAQLIKNSEPCYLDEIP------------------------QDITDLIKSCLIKDPASRISMEQIKKIHWV
.|.|||.|... .||.|.    . ..  |.|..  .. |..                          ..  |.||.|| |||..|.. |||..  |.
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93040.m00043.AA CAMKL 14-266 26 5.6e-62 196.53 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-297/297
Sequence Identity: 26% (79 aa)

YILDKFIAEGGFSEVWLGRH-EESNTQVAIKVFYKRTMD-SKIKLNDFKN-----------EVHIHKQLL---HPFLVRFYETL-------ENCFYYYII
|.. | . .|.|..| |..|    ...||||.  |. .    .... . .           |..|.|.|    ||  ...||..       |.  ..|..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MEFLPGKT--LKQMIVDK----SSIEDNTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDN--NIRLIDFGIS---RP--ITNNTVQNDKQGTLY
||  .|    | ..|| .     ... .  |    | . |..|.|    ..| |.|. |. .|...  || .|||| |   ||  ....   .   |.. 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YFAPERFNE--E-TVTTKVDIWSFGVILYYMFSKTLPFSGESP-------AETAQLIKNSEPCYLD---EIPQDITDLIKSCLIKDPASRISMEQIKKIH
| ||| |.   .     |||||| ||||| |   .||| ...          .  .....  .| .   ... |  |||.. | ..|  |....||..  
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WV
|.
WM
Kinase 93040.m00043.AA Ciliate-E2-Unclassified 14-266 22 1.6e-59 204.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-352/352
Sequence Identity: 22% (79 aa)

YILDKFIAEGGFSEVWLGRHEESNTQV-------AIKVFYKRTMDSK-------IKLNDFKNEVHIH----------KQLLHPFLVRFYETLENCFYYYI
|.. | | .|||..|.. .|.. . |.        |... .. . .|       . .|  |.  |            ... |||.|..... .. .. ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEFLPGKTLKQMIVDKSS-----------------IEDNTLR-----TWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDN---NIRLIDFGISR-PI
.||...|..|.|.| ....                 ....  .     ... | | ...|||    ..| |.| .|...|...   .|..||||||. ..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

TNNTVQNDKQ----------------GTLYYF----APERFNEETVT----TKVDIWSFGVILYYMFSKTLPFSGESPAE----------------TAQL
.||  . ..|                ||..|     ||| . ..        |.||||.|||||.|   ..||....  .                  | 
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

IKNSEPCYL--------DEIPQDITDLIK----SCLIKDPASRISMEQIKKIHWV
||. ....         . ...   |.|.    ..| |.| .||..|||.. .| 
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 93040.m00043.AA Ciliate-E2 14-266 22 8.3e-54 183.07 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

YILDKFIAEGGFSEVWLGRHEESNTQVAIKVFYKRT----------------MDSKIK--LNDFKNEVHIHK----------------QLLHPFLVRFYE
|.. | | .|.|. |..... . . |.|||... .                 | ...|  .. .|.| || .                || ||.....||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

TLE--NCFYYYIIMEFLPGKTLKQMIV-------------------DKSSIEDNTLR-------TWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDNN
. .  .  ..|..||.. |..|.. |                      . |    |.        .... . |. |||    ..| |.| .|...     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRLIDFGISRPITNN-----------TVQNDK----------------------QGTLYYFAPERFNEET---------VTTKVDIWSFGVILYYMFSKT
| .||||.|. ....             .. |                       ||..| ||| .| .           ..|.||||.|||||.| .. 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFSGESPAETAQLIKN-----SEPCY-------------LDEIPQDITDLIKS----CLIKDPASRIS-MEQIKKIHWV
.||         | ||.     ..|..              ....|.  ||||     .| |||  ||. .|||.. .| 
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93040.m00043.AA MARK 14-266 29 1.7e-49 160.01 In-house 1-262 (262) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-262/262
Sequence Identity: 29% (77 aa)

YILDKFIAEGGFSEVWLGRHEESNTQVAIKVFYKRTMDSKIKLNDFKNEVHIHKQLLHPFLVRFYETLE--NCFY-YYIIMEFLPGKTLKQMIVDK--SS
| . | | .|....| |..|  ....||||.  |  ..   ... .. |..|.|.| ||  ...... |  .     |.|||  .|. | . |. .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IEDNTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDN--NIRLIDFGISRPITNNTVQNDKQGTLYYFAPERFNEETVT-TKVDIWSFGVILYYM
.. .  |.   | . |. |.| .  ..| |.|. |. .|...  || .|||| |. |....  |   ||. | ||| |. .  . .|||||| ||.||.|
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

FSKTLPFSGES--PAETAQLIKNSEPCYLDEIPQDITDLIKSCLIKDPASRISMEQIKKIHWV
 . ..|| | .    |  . | . .... . .. .. .||.. |  .|  |...|.| |  |.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 93040.m00043.AA TKL 20-264 18 2.2e-47 163.77 In-house 1-364 (364) Show / Hide 
Range on Protein: 20-264
Range on HMM: 1-364/364
Sequence Identity: 18% (68 aa)

IAEGGFSEVWLGRHEESN--------TQVAIKVFYKRTMDSKIK-----------------------LNDFKNEVH-IHKQLLHPFLVRFYETLENCFY-
| .|||.||. |..   .        . ||.|.| .. .|.. |                       ...|..|.  ....| || .|.|.    .. . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YYIIMEFLPGKT-LKQMIVDKSSIEDNTL-RTWAVQFLMAIDYLHT-------IPQVCHMDLKASNLIVDSDNN--------------
            ..|.||. || . | ...          .   || .   ...|||.        |.. | ||| .|. ||....              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

IRLIDFGISRPITNNTVQND--------------------KQGTLYYFAPERFNEE----------------TVTTKVDIWSFGVILYYMFSKTLPFS-G
. . |||.|| ..... .||                    . ||... ||| ....                . ..|.|..|||..|. ...  .|..  
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

ESPAET---------AQLIKNSEP-------------CYLDEIPQDITDLIKSCLIKDPASRISMEQIKKIH
 .. .          .. ......             |  . .|... .|.. |   || .| |...|.|. 
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 93040.m00043.AA ULK 14-266 23 2.4e-45 156.99 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-324/324
Sequence Identity: 23% (78 aa)

YILDKFIAEGGFS-EVWLGRHEES---NTQVAIKVFYKRTMDSKIKL-------NDFKNEVHIHKQLL---HPF--LVRFYETLENC--FYYYIIMEFLP
|.|.. . .| |   |  ||....   | .||.|.  |  |  | ..       . .|||. | |.|    ||.   |..|. .|.    ..|||||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GKTLKQMIVDK---------SSIEDNTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDNN------------IRLIDFGISRPITNNTVQNDKQ-
| .|.| |  .           .. .  .    |.. .  .||   .. | |.| .|. .  ..             . . ||| .. . ||. . ..  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GTLYYFAPERFN----EETVT-TKVDIWSFGVILYYMFSKTLPFSGESPAETA----QLIKN---------SEPCYLD------EIPQDIT
         || .| ||. ..    ..  .  |.||||.|.|.|.|     ||..  . ..     .||.|          .|   .       | ... 
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLIKSCLIKDPASRISMEQIKKIHWV
|||. .|..|.  ||| |.| .. |.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 93040.m00043.AA ULK 14-266 23 2e-44 152.98 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-329/329
Sequence Identity: 23% (77 aa)

YILDKFIAEGGFSEVWLGRHEES----NTQVAIKVFYKRTMDSKIKLND-------FKNEVHIHKQLL--------HPFLVRFYETLENC--FYYYIIME
|.|.. . .| |  |  ||....    | .||.|.  | .|. | ....       .|||. | |.|         ||  |..|. .|.    ..|||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FLPGKTLKQMIVDK----------SSIEDNTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDNN------------IRLIDFGISRPITNNT---
. .| .|.| |  .            .. .  .    |.| .  .||   .. | |.| .|  .. ..             . . ||| .. ..|..   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

-VQNDKQ------GTLYYFAPERFN----EETVT-TKVDIWSFGVILYYMFSKTLPFSGESPAETA-----QLIKN---------SEPCYLDE------I
 .           || .| ||. ..    ..  .  |.||||.|.|.|.|     ||..  . ..      .||.|         ..|   .       |
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

PQDITDLIKSCLIKDPASRISMEQIKKIHWV
 ... |||. .|..|.  ||| |.. .. |.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 93040.m00043.AA CAMK-Unique 14-266 20 2.4e-43 140.8 In-house 1-363 (363) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-363/363
Sequence Identity: 20% (74 aa)

YILDKFIAEGGFSEVWLGRHEESNTQVAIKVFYKRTMDSKIKLN-----------------DFKNEVHIHKQLLHPFLVRFYET----LENCF-------
|.. . | .|.|..|  .   |  .  |.|.. | |  .|...                   .|.|. | | . || ....|..     .          
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------YYYIIMEFLPGKTLKQMIVD--------------------KSSIED--NTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSD------
        |.||.||...|..|.. |..                    . . .   .  ..   . |.|. |.| . .. | |||. |. | .       
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQ-DIVHRDLKLENIMVCYSFKDNNH

----------NNIRLIDFGISRPITNNTVQN---DKQGTLYYFAP--------------ERFNEETVTTKV----DIWSFGVILYYMFSKTLPFSGESPA
          ..| |.|||... . .| .        ||..| ||              |  |.     ..    |||| |||.|||..  .|| .|. .
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------ETAQLIKNSEPCYLDEIPQDI--------TDLIKSCLIKDPASRISMEQIKKIHWV
        |. . |.  ..|..|.   ..        .|..| |.  ||..|.| .....  |.
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 93040.m00043.AA STE 14-266 18 1.2e-40 141.24 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-359/359
Sequence Identity: 18% (66 aa)

YILDKFIAEGGFSEVWLGRHE------ESNTQ---------VAIKVFYKRTMDSKIK--------------LNDFKNEVHIHKQLL--HPFLVRFYETLE
. . ..| .|.| .| ....       ... .         .|||.  ... ..|..              ......|. |.|..   ||. |..| . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-------NCFYYYIIMEFLPGKTLKQMIVDKSSIE--------------DNTLRTWAVQFLMA-IDYLHTIPQVCHMDLKASNLIVDSDNNIRLIDFGIS
       |. . .|.||...| .| ..|  | ..                . ... ..| | .  .|||    . | |.|..|  .     . |.|||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLCDFGVC

RPITNN-----------------TVQNDKQGTLYYFAPERFNEET------VTTKVDIWSFGVILYYMFSKTLPFSGESPAETAQLIK------------
  .|..                    |   ||  . |||. . ..       .||.||||.|  .  |     |.. ..| .   .|             
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----NSEPCYLDEIP-------------------QDITDLIKSCLIKDPASRISMEQIKK--IHWV
    .  |   |..                    ..  | |. ||.|||  | . .|  |    ..
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 93040.m00043.AA TyrKc 14-264 25 3.7e-17 54.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-264
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

YILDKFIAEGGFSEVWLGRHEESNTQVAIKVFYKRTMDSKIKLNDFKNEVHIHKQL--LHPFLVRFY----ETLENCF----YYYIIMEFLPGKTLKQMI
  |.| . || | ||..|.     .|||.|.  . .      . || .|  | ..|   || .||.|    .  .| |     ..|.||. |.  ||. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYL

VDKSS-IEDNTLRTWAVQFLMAIDYLHTIPQVCHMDLKASNLIVDSDNNIRLIDFGISRPITNN--------TVQ-----NDKQ-GTLYYFAPERFNEET
 ..   .   .|  ...|     .|||   .. | || | |  |.... ..  ||| || |..         .       . |    .   ||| .|. .
RKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

VTTKVDIWSFGVILYYMFSKTLPFSGE------SPAETAQLIKNS--EPCYLD-------EIPQDITDLIKSCLIKDPASRISMEQIKKIH
 ||| |.||||| .. .|.   .   .      |..|  ...|.    |.  .       . |... ...|.|   ||..| ....|... 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93040.m00043.AA Pkinase_Tyr 14-78 32 1.5e-07 26.24 Pfam 1-70 (270) Show / Hide 
Range on Protein: 14-78
Range on HMM: 1-70/270
Sequence Identity: 32% (23 aa)

YILDKFIAEGGFSEVWLGRHE----ESNTQVAIKVFYKRTMDSKI-KLNDFKNEVHIHKQL-LHPFLVRFY
 ...| . || | ||..|.      . ...||.|.  | . ...  .. || .|. | |||  || .||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY
Kinase 93040.m00043.AA Pkinase_Tyr 180-269 30 5.5e-07 24.28 Pfam 182-270 (270) Show / Hide 
Range on Protein: 180-269
Range on HMM: 182-270/270
Sequence Identity: 30% (30 aa)

APERFNEETVTTKVDIWSFGVILYYMFSKT-LP-FSGESPAETAQLI-KNSEPCYLDEIPQ----DITDLIKSCLIKDPASRISMEQIKKIHWVSEI
||| .|.   ||| |.||||| .. .|.    | . | |..|  ..| ..    |  ..|.    .| ||.|.|  .||. | ....|     ....
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED---GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI-----HEQL