Gene 96844.m00037 (T.vaginalis)

96844.m00037

Species: T.vaginalis
Alias: TvagK0130, 96844.m00037
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag4

Sequence

Name Sequence Type Origin Length Description Download
96844.m00037.AA Protein None 498 None Fasta, JSON
96844.m00037.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 96844.m00037.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96844.m00037.AA CAMKL 10-261 40 9.90000000001e-133 425.98 In-house 1-297 (297) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-297/297
Sequence Identity: 40% (122 aa)

YILLQIIGQGNFSKVKLAEH-KETHQRYAVKIIKKSKLEENPELSSK-----------IQREIALMKILD---HTHIIKLIEIAESPRH------LFIIQ
|.... .|.|.|.|||||.| . | ...|.|||.|.|. ..|  ...           |.|||..|| |.   | .|||| |. | |.|      .... 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAENGE--LFDYLVARRY----LSVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHN--NVKIADFGFARWLK------YSTTQTSCGSPHYA
||...||  ||||.|....    .. .|  |.||||. ...|.||.||.|||.||||.|||...  |.||.||||. . .        .  |.||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVIRG--IPYNGQKADIWSCGVILYALLAGRLPFNEP--------NFKDLVSKIKNGQYRMPDF---PAVIKDLVAKMLCVNPECRITIEQIKHHKAF
|||.. |   ||.|.|.|||||||||||.. |.|||...        |.  |  ||. | |..| .   .   .||  ||| |||| |.||.||. |. .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 96844.m00037.AA AMPK 10-261 48 2.9e-130 388.88 In-house 1-254 (254) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-254/254
Sequence Identity: 48% (124 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKLEENPELSSKIQREIALMKILDHTHIIKLIEIA-ESPRHLFIIQEYAENGELFDYLVARRYLSV
||. . || | | |||...|. | .  |.||. | |. .  . . .||||| ..|.. | |||.| |.  |.|. .|.. ||. .|||||| | .. |. 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQ-DMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

EESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNNVKIADFGFARWLKYSTT-QTSCGSPHYAAPEVIRGIPYNGQKADIWSCGVILYALLAGRLP
.|. | | ||| |..|.|  .| |||||||||||| ..|.||.|||     |   .  |.|||| |||||.| | .|.| . |||||||||||.| |.||
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FNEPNFKDLVSKIKNGQYRMPDF-PAVIKDLVAKMLCVNPECRITIEQIKHHKAF
| ..|  .|  |||||.|  |.|    .|||. .||.|.|. ||||..|. |. |
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 96844.m00037.AA CAMK 15-261 28 3e-124 402.48 In-house 1-425 (425) Show / Hide 
Range on Protein: 15-261
Range on HMM: 1-425/425
Sequence Identity: 28% (122 aa)

IIGQGNFSKVKLAEHKETH------------QRYAVKIIKKSKLEE------------------------NPELSSKIQREIALMKI-------LDHTHI
..|.|.|.||||..||.|             |..|.|||.|.|| .                        .|.   ...|||..||        ||| .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLIEIAESPRH-------------------LFIIQ---EYAENGEL----FDYLVAR---------------RYLSVEESMRIFRQIIYGLDYLHSRGI
|||.|. |.|..                   ....    ||...|||    |||.|..               .... .|  |.||||. ...|.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENLLLDSH-----------------NNVKIADFGFARWLK-------------------------YSTTQTSCGSPHYAA-PEVIRG------
.||||||||.|||..                 ||.||.|||||. ..                             .|.||.|.|.| |||..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------IPYNGQKADIWSCGVILYALLAGRLPFNEP-------------NFKDLVSKIKNGQYRMPDFP-------------------------AVIKD
       .|| |.|.|.||||||||..| |..||...             | ..|  ||..|.|..|...                         .  ||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVAKMLCVNPECRITIEQIKHHKAF
|. |||.|.|| |.||||.. |. .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 96844.m00037.AA BRSK 10-261 49 2.7e-112 379.39 In-house 1-254 (254) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-254/254
Sequence Identity: 49% (126 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKLEENPELSSKIQREIALMKILDHTHIIKLIEIAESPRHLFIIQEYAENGELFDYLVARRYLSVE
|.|    |.|   .|||  |. | .. |.||| | || . . .  |. ||||.||  || |..|. .. |  . |. | |. . |||||||| .  |   
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

ESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNNVKIADFGFAR-WLKYSTTQTSCGSPHYAAPEVIRGIPYNGQKADIWSCGVILYALLAGRLPF
|  . ||||| .||. ||. ||||||||||||||  ||.|||||| |   .| .   ||||||||| ||||||. | |.|||.||||||||||| | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

NEPNFKDLVSKIKNGQYRMPDF-PAVIKDLVAKMLCVNPECRITIEQIKHHKAF
   |   |  |.|.| . || | .. . ||  .|. |.|. ||....|. |  .
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase 96844.m00037.AA MARK 10-261 43 1.3e-110 362.75 In-house 1-262 (262) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-262/262
Sequence Identity: 43% (115 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKLEENPELSSKIQREIALMKILDHTHIIKLIEIAE--SPRH-LFIIQEYAENGELFDYLVAR--R
| .|. ||.|...||||| || |....|.||..| || .. .. ....|||..|| ||| .|||| .. |   ..| ...| |||..|||.||..|.  .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWM-KNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

YLSVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHN--NVKIADFGFARWLKYST-TQTSCGSPHYAAPEVIRGIPYNGQKADIWSCGVILYAL
.|. ||  ||||||.... |.||..|.|||.||||.|.|...  |.||.||||..  .  .   | ||.| |.|||.. . ||.|.|.||||.||.||..
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LAGRLPFNEPN--FKDLVSKIKNGQYRMPDFPAV---IKDLVAKMLCVNPECRITIEQIKHHKAF
. |..|| . .  .|.|  || .|.|. |..  |   ...|. ..| |||| |.|||.|  |. .
VCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 96844.m00037.AA S_TKc 10-261 36 4.5e-104 352.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKLEENPELSSKIQREIALMKILDHTHIIKLIEIAESPRHLFIIQEYAEN--GELFDYLVARRY--
| .|..||.| |.||... ||.|....|.||||            .|.|||...|  .| .|.||... ..  ||... ||...  |.||||.. |..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNNVKIADFGFARWLKYSTTQTSCGSPHYAAPEVIRGIPYNGQKADIWSCGVILYAL
    ..  .  ....||. .|.|.||.||.||||||||.|||.  ..||.|||.|| |      | ||.|.| ||||.   .|.. |.|.||||.||| .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LAGRLPFNEPNFKDLVSKIKNGQYRMPDFPAVIKDLVAKMLCVNPECRITIEQIKH-------HKAF
|.|. ||   . . .  ||.         .   ||.. |.|...|| |.|. .. .       |  |
LCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96844.m00037.AA QIK 10-261 42 1.2e-97 330.72 In-house 1-272 (272) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-272/272
Sequence Identity: 42% (117 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKLEENPELSSKIQREIALMKILDHTHIIKLIEIAESPRHLFIIQEYAENGELFDYLVARRY----
| . . || |||  |||| |. | .. |.||| ||.|.|  .|  |. ||...|| |.| ||||| .. |. . ..|. ||..|||.||||..       
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE-NLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LSVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNNVKIADFGFARWLKYST-TQTSCGSPHYAAPEVIRGIPYNGQK
                .. .|  |.| ||. . .|.|.|.| ||||| ||.|||.  |.|||||||  | |     .| |||| |||||.  |. |.| |
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

ADIWSCGVILYALLAGRLPFNEPNFKDLVSKIKNGQYRMPDF-PAVIKDLVAKMLCVNPECRITIEQIKHHKAF
.|||| ||.||.| .| |||  .. . | ...  |..|.| | .    .|. .|| |.|| |.||.||. |.  
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 96844.m00037.AA Pkinase 10-261 36 3.9e-96 330.47 Pfam 1-293 (293) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-293/293
Sequence Identity: 36% (108 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKLEENPELSSKIQR--EIALMKILDHTHIIKLIEIAESPRHLFIIQEYAENG----ELFDYLV--
| ....||.|.|..|... || | ...|||||||.  .|...      |  ||..|| |.| .|..|... |...|. ...||.|.|    .||||.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

ARRYL--SVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNNV----KIADFGFAR---WLKYSTTQTSCGSPHYAAPEVIRGIPYNGQKADIW
... .  | .|  ....||. ||.|.||.||.||||||||.|.|.....    ||.|||.|.   . ..| ..| ||.|.|.||||||| .| |.|.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SCGVILYALLAGRLPFNEP----NFKDLVSKIKNGQYRMPDFP-------------------------AVIKDLVAKMLCVNPECRITIEQIKHHKAF
|||.||| .| ||.|| .     |  |   .|..  .. ..|.                            ||.. ..||..|..|.|.|||..|. |
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96844.m00037.AA GIN4 56-261 48 1.3e-90 289.6 In-house 81-293 (293) Show / Hide 
Range on Protein: 56-261
Range on HMM: 81-293/293
Sequence Identity: 48% (104 aa)

IQREIALMKILDHTHIIKLIEIAESPRHLFIIQEYAENGELFDYLVARRYLSVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNN-VKIADFG
| ||| .||...|. ...| .. |    |... |||| ||||.||| .  |   | ...||||| |. | |. .||||||||||||||. .| .||||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

FARW-LKYSTTQTSCGSPHYAAPEVIRGIPYNGQKADIWSCGVILYALLAGRLPFNEP--NFKDLVSKIKNGQYRMPDF---PAVIKDLVAKMLCVNPEC
 |   ..    .||||||||||||.. ||||.|  .|.|||||||.||| |.|||.|   | ..|. |.. |.| ||.        .||..|.| | || 
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEK

RITIEQIKHHKAF
||.. .| .|   
RIKTRDILKHPLI
Kinase 96844.m00037.AA ULK 10-261 26 2.6e-87 296.4 In-house 1-329 (329) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-329/329
Sequence Identity: 26% (89 aa)

YILLQIIGQGNFSKVKLAEHKETH----QRYAVKIIKKSKLEENPELSS------KIQREIALMKILD--------HTHIIKLIEIAESP--RHLFIIQE
|.| ...|.| | ||  ...|.|.    . .|.|.| |.|. ... ..        ...|| .|| |.        | .|.||... |..   ...||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAENGELFDYLVARRYLSVEE----------SMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNN------------VKIADFGFARWLKYS-----
| . | |..|.  ...|. ..             .|.||. |. .||...| |||.||.| |.. ..             .||||||||. . ..     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-TTQTS-----CGSPHYAAPEVIR----GIPYNGQKADIWSCGVILYALLAGRLPFNEPNFKDLV-----SK----------IKNGQYRMPD------FP
 .. ..     ||.| | ||...     ..||.  |.|||| |.|.| .| |. ||... | |..     .           ||. . . |.      . 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

AVIKDLVAKMLCVNPECRITIEQIKHHKAF
  .|||  .||..... ||..|.. .|. |
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 96844.m00037.AA Ciliate-E2 10-261 25 1.1e-86 294.3 In-house 1-365 (365) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YILLQIIGQGNFSKVKLAEHKET-----------------------HQRYAVKIIKKSKLEENPELSSKIQ---------REIALMKILDHTHIIKLIEI
|.....||||||..|........                        . ||.||.||...|.     . ..          |  ....|.| .|||..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

AE--SPRHLFIIQEYAENGELFDYLV------------ARRYLSVEESMRIFRQIIY---------------GLDYLHSRG-ICHRDLKPENLLLDSHNN
 .  .  ..... ||.. |.||||.             .  |.. .|  .|..||..               .| ||||.. |.|||.||||.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKIADFGFAR----------------WLKYST------------------TQTSCGSPHYAAPEVIRGIPYNG--------QKADIWSCGVILYALLAGR
.||.|||...                |...                    ..| ||.|.| |||...| .|..         |.||||.||||| .| |.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFNEPNFKDLVSKIKNGQYRMP-------------------DFPAVIKDLVAK----MLCVNPECRIT-IEQIKHHKAF
.||          .||..... |                   . .   |||  |    ||...|| ||| .|||. |. |
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 96844.m00037.AA ULK 10-261 28 1.6e-86 293.73 In-house 1-324 (324) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-324/324
Sequence Identity: 28% (94 aa)

YILLQIIGQGNFS-KVKLAEHKETH---QRYAVKIIKKSKLEENPELSS------KIQREIALMKILD---HTH--IIKLIEIAESP--RHLFIIQEYAE
|.| ...|.| |  ||  ...|.|.   | .|.|.| |.|. ... ..       ....|| .||.|.   | .  |.||... |..   ...||.|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFDYLVARRYLSVEE----------SMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNN------------VKIADFGFARWLKY-STTQTSC-
 | |..|.  ...|.. .             .|.||. |. .||...| |||.||.|.|.  ..             .||||||||. . . .  |. | 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSPHYAAPEVIR----GIPYNGQKADIWSCGVILYALLAGRLPFNEPNFKDLV----SK----------IKNGQYRMPDFP------AVIK
         |.| | ||...     ..||.  |.|||| |.|.| .| |. ||... | |..    .           ||| . . |. |        .|
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLVAKMLCVNPECRITIEQIKHHKAF
||  .||..... ||..|.| .|. |
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 96844.m00037.AA Pkinase_Tyr 10-157 31 6e-24 81.72 Pfam 1-159 (270) Show / Hide 
Range on Protein: 10-157
Range on HMM: 1-159/270
Sequence Identity: 31% (50 aa)

YILLQIIGQGNFSKVKLAEHK----ETHQRYAVKIIKKSKLEE-NPELSSKIQREIALMKIL-DHTHIIKLIEIAE-SPRH--LFIIQEYAENGELFDYL
 .... .|.|.| .|.... |    .|..  |||..| .  .| |  .. .  ||...|| | .| .|..|. .     ..  ..|. ||...| | |||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

VA----RRYLSVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNNVKIADFGFAR
 .    .. |....   . .||  |..||.|... ||||   | |... | |||.||| ||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 96844.m00037.AA TyrKc 10-261 24 7.5e-24 86.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-261
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKLEENPELSSKIQREIALMKIL--DHTHIIKLIEIAESP-------RHLFIIQEYAENGELFDYL
  |....| |.| .| ... |   .  ||| .|...          . ||. .|. |  .| .|..|. .. ..         |.|. ||...| | |||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

VARRY-LSVEESMRIFRQIIYGLDYLHSRGICHRDLKPENLLLDSHNNVKIADFGFARWLKYS------TTQTSC----GSP-----HYAAPEVIRGIPY
 ..|  |....   .  ||  | .||||... ||||   | |... . |||.||| .| ..        .   .     |.         |||.|    |
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NY

N--GQKADIWSCGVILYALLA-GRLPFNE-----PNFKDLVSKIKNG--QYRMPD--------FPAVIKDLVAKMLCVNPECRITIEQIKHHKAF
.    | |.|| || .. ..  |  |  .      . .... ..|.|    ..|.         |. . ..  .    .||.| | ..|  |. |
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 96844.m00037.AA GIN4 10-46 45 3e-06 15.31 In-house 1-37 (293) Show / Hide 
Range on Protein: 10-46
Range on HMM: 1-37/293
Sequence Identity: 45% (17 aa)

YILLQIIGQGNFSKVKLAEHKETHQRYAVKIIKKSKL
. | . .| |   ||.|| ..|| || |||.| | |.
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKI