82762.m00198

Species: T.vaginalis
Alias: 82762.m00198, TvagK0023
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
82762.m00198.AA Protein None 377 None Fasta, JSON
82762.m00198.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 82762.m00198.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82762.m00198.AA CAMK 16-263 24 8.20000000001e-117 378.1 In-house 1-425 (425) Show / Hide
Range on Protein: 16-263
Range on HMM: 1-425/425
Sequence Identity: 24% (102 aa)

VIGEGAFSHVVLAFHE-TQK-----------TYYACKIVPKARLSS-------------------------SSLEERFEEEIRINQQ-------LHHPGV
..|.|.|. | |..|  |..           . .|.||..| .|..                          . ..... ||.| ..       |.|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGLIDIIKD-------------------ETNYYVVM---EFCPNGEL----FQFIVDR---------------GRLSEAEAKPKIKMILDTVRYLHSLGI
. |.... |                   ....| ||   |.|..|||    |..||..               ||..|.||.  .. |.. |.|.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDLKPENILLDQY-----------------GNPKVSDFGLSRFVGP------------------------DNLVSTPCGSPCYAS-PECISG------
 ||||||||||||.                  .| |..|||..... |                        . . .|.||.|.|.. || ..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QNYNGLTSDVWSCGVVLFAMVTGQLPWTKR-------------NQSQLFEQIRNGDYT-IPNFLSV-----------------------QCAS
       . | |  .|.|||||.|..|..| .|.                |...|||.|..|.|. .| ..|                        .| .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISGLMTVDSEERLTVEQALHHQWL
||.....|| |.|.|.||.| |.|.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 82762.m00198.AA AMPK 11-263 42 1e-110 329.9 In-house 1-254 (254) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-254/254
Sequence Identity: 42% (107 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLSSSSLEERFEEEIRINQQLHHPGVVGLIDII-KDETNYYVVMEFCPNGELFQFIVDRGRLSEA
||.   ||||.|  | .. |.. ... | ||  | .. ...  || . ||.| . . || .. | ..| . .|  ..|||. ..|||| .|| .|||.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYGNPKVSDFGLSRFVGPDNLVSTPCGSPCYASPECISGQNYNGLTSDVWSCGVVLFAMVTGQLPW
||.  .. |.  | |.| ..|.||||||||.|||.  | |. |||||      .. .| |||||||.|| |||. |.|.  |.|||||.|.||. | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

TKRNQSQLFEQIRNGDYTIPNFLSVQCASLISGLMTVDSEERLTVEQALHHQWL
   |...|.  |.||.|.|| ||| ....||... .|| ..|.|...   |.|.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 82762.m00198.AA CAMKL 11-263 35 2.1e-108 347.11 In-house 1-297 (297) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-297/297
Sequence Identity: 35% (105 aa)

YILRGVIGEGAFSHVVLAFH-ETQKTYYACKIVPKARLS-SSSLEERFEE-----------EIRINQQLH---HPGVVGLIDIIKDETN------YYVVM
|..  ..|.|.|. | || |  |... .| ||. | ...     . ..             ||.| ..|.   || .. | ..| ....      .| ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCPNGE--LFQFIVDR----GRLSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYG--NPKVSDFGLSRF-----VGPDNLVSTPCGSPCYA
| |..||  ||..|| .    ||..| ||.   . |.. | |.||.|| |||.||||||||. |  | |..|||.| .     .||... .| ||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPECISG--QNYNGLTSDVWSCGVVLFAMVTGQLPWTKR--------NQSQLFEQIRNGDYTIPNFLSV-QCASLISGLMTVDSEERLTVEQALHHQWL
.|| ..|  . |.|   |.|||||.|.|||.|.||.           |.  |...|. | | .| ...| .| .||.....|. |.| |..| . | |.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 82762.m00198.AA S_TKc 11-263 33 1.5e-93 318.05 SMART 1-231 (231) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLSSSSLEERFEEEIRINQQLHHPGVVGLIDIIKDETNYYVVMEFCPN--GELFQFIVDRGR---
| .  .||.|||. | .. |   . ..|.||..          |... ||.| .. ||| .| |.|.. | ...|.|||.|..  |.||..|..|||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYGNPKVSDFGLSRFVGPDNLVSTPCGSPCYASPECISGQNYNGLTSDVWSCGVVLFAM
   ..| .|.  .. |.. . |.||.|| ||||||||||||.  . |..||||.|..      .| ||.| | .|| .    |..  .|.||||..|. |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VTGQLPWTKRNQSQLFEQIRNGDYTIPNFLSVQCASLISGLMTVDSEERLTVEQALH-------HQWL
..|. |.   .. ..|..|.          | .. ..|......| |.|.|. .||.       |.|.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 82762.m00198.AA MARK 11-263 37 6.4e-93 304.05 In-house 1-262 (262) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-262/262
Sequence Identity: 37% (99 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLSSSSLEERFEEEIRINQQLHHPGVVGLIDIIK--DETN-YYVVMEFCPNGELFQFIVDR--GR
| .  .||.|... | || |   .. .| ||..| .|.     . .. ||.| ..|.|| .. | ..|   .|..  |..|| ...|||...|. .  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYG--NPKVSDFGLSRFVGPDNLVSTPCGSPCYASPECISGQNYNGLTSDVWSCGVVLFAMV
|.| ||.   . |.  | |.|| .| |||.||||||.|. |  | | .|||.|. . |... .| ||.| |..|| .... |.|   |.||.||||..||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGQLPWTKRN--QSQLFEQIRNGDYTIPNFLSVQCASLISGLMTVDSEERLTVEQALHHQWL
.|..|.   .  . .|...|..|.|.|| ..|..| .||. |.||. ||| |.|. . | |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 82762.m00198.AA Pkinase 11-263 31 9.4e-85 292.67 Pfam 1-293 (293) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLSSSSLEERFE-EEIRINQQLHHPGVVGLIDIIKDETNYYVVMEFCPNG----ELFQFIV--DR
| . ..||.|.|. | .. |      .|.||..| . .|. .....   ||.| . |.|| .| |.|.  |....|.|||.|..|    .|| .|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--SEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYGNP----KVSDFGLSRF--VGPDNLVSTPCGSPCYASPECISGQNYNGLTSDVWSC
|..  || |.|  .. ||  . |.|| || ||||||||||.|. |..    |..||||...    ..   .|.||.| |..|| | |..| |  .|.|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLFAMVTGQLPWTKR------NQSQLFEQIRNGDYTIPNFLS---------------------VQCASLISGLMTVDSEERLTVEQALHHQWL
|..|. |..|..|.  .      .| |....|. ...  . . .                       | ..|... ..| ..|.| ||.|.| |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 82762.m00198.AA RAD53 11-263 31 3.9e-84 250.42 In-house 1-305 (305) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-305/305
Sequence Identity: 31% (97 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLS---SSS--LEERFEEEIRINQQLHHPGVVGLIDIIKD-ETNYYVVMEFCPNGELFQFIVDRG
|......| |.|. | ||.  .    .| ||. | ...   ...   ......|..| . |.|| .. ..||. . ...|| |.|.  .|||| .||...
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

R----LSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYGNP------------------KVSDFGLSRFVGPDNLVSTPCGSPCYASPECISG
|    ..|...|   . ..| |.|||..||.||||||||||.. .. .                  |..|||||.||| . .  | ||.| |  || | .
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

QNY------------NGLTS--DVWSCGVVLFAMVTGQLPWT-KRNQ----SQLFEQIRN-GDYTIPNF-------LSVQCASLISGLMTVDSEERLTVE
.              .| |.  |.|| |..|. . .| .|    . |     ||||||.| | |   .|        |   ..||... .|| |.|.|..
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKY---HFPHPYWDRISEEAKDLIKWMLCVDPEKRYTID

QALHHQWL
.|| |.|.
EALNHPWM

Kinase 82762.m00198.AA QIK 11-263 36 1.6e-80 273.83 In-house 1-272 (272) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-272/272
Sequence Identity: 36% (99 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLSSSSLEERFEEEIRINQQLHHPGVVGLIDIIKDETNYYVVMEFCPNGELFQFIVDRGR-----
| .   || | |  | || |   ||  | ||. | .| .. |. . . |. |  .| || .. | ...  .   |.|.|.|.|||.|  ..  ||     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYGNPKVSDFGLSRFVGPDNLVSTPCGSPCYASPECISGQNYNGLTS
               ..| ||. . . |.  | |.|...| ||||| ||||||.  | |. |||.| .  .. | .| |||| || ||   |..|.|  .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DVWSCGVVLFAMVTGQLPWTKRNQSQLFEQIRNGDYTIPNFLSVQCASLISGLMTVDSEERLTVEQALHHQWL
|.|| ||||...|.| ||    .  .| . .  | . || |.|. |..||   ..|| | |.|..| . |.|.
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 82762.m00198.AA Ciliate-E2 11-263 24 2.8e-72 246.42 In-house 1-365 (365) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YILRGVIGEGAFSHVVLAFH-ETQKTY----------------------YACKIVPKARLSSSSLEERFEEEIR----------INQQLHHPGVVGLIDI
|..  .||.|.|. | .. . ..|| .                      || ||. |  . . . |..   ||.          | .|| || .. ... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IK--DETNYYVVMEFCPNGELFQFIVDR-----------GRLSEAEAKPKIKMILD---------------TVRYLHSLG-ISHRDLKPENILLDQYGNP
 .  |..|.| |||.|  |.||..| ..           ....| |.|  .| ||.                ..|||| . | |||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVSDFGLSRFVGPD--------------------------------NLVSTPCGSPCYASPECISGQNYNG--------LTSDVWSCGVVLFAMVTGQLP
|..|||||... .|                                |.. | ||.| | .|| ..|..|..          .|.||.||.|. |..|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WTKRNQSQLFEQIRNGDYTIPNF------------------LSVQCASLISG----LMTVDSEERLT-VEQALHHQWL
.        ..|| .... .|..                  .| .|  ||.     .. .| |.|.|  ||.| |.|.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 82762.m00198.AA ULK 11-263 25 1.6e-70 240.59 In-house 1-324 (324) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-324/324
Sequence Identity: 25% (84 aa)

YILRGVIGEGAFS-HVVLAF-HETQ--KTYYACKIVPKARLSSSSLE-------ERFEEEIRINQQLH---HPG--VVGLIDIIKDE--TNYYVVMEFCP
|.|. ..|.|.|   |  .. ..|.  . |.|||...|  .. ...|       . .. ||.| ..|.   ||   .| |.|. ..   .|.| .||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFQFIVDR---------GRLSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYGN------------PKVSDFGLSRFVGPDNLVSTPC--
 | |.|.|  .         .|||| ||.  .| |.   ..||. .| |||.||.|||.                  |..|||....|  .|.  . |  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSPCYASPECIS----GQNYNGLTSDVWSCGVVLFAMVTGQLP---WTKRNQS----QLFEQ-------IRNGDYTIP-----NFLSVQCAS
        |.| | .|. ..    ...|.   .|.|| |.... |..|. |   | ...|     .| ..       |.|    .|     . .| .| .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LISGLMTVDSEERLTVEQALHHQWL
||......| ..| . |. ..| |.
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 82762.m00198.AA ULK 11-263 25 7.7e-69 235.01 In-house 1-329 (329) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-329/329
Sequence Identity: 25% (84 aa)

YILRGVIGEGAFSHVVLAF-HETQ---KTYYACKIVPKARLSSSSLEER-------FEEEIRINQQLH--------HPGVVGLIDIIKDE--TNYYVVME
|.|. ..|.|.|  |  .. ..|.   . ..|||...|  .. .. |         .. ||.| ..|.        || .| |.|. ..   .|.| .||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCPNGELFQFIVDRGR----------LSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQY------------GNPKVSDFGLSRFVGPDN----
.|. | |.|.|  ...          ||| ||.  .| ||   ..||. .| |||.||.|||..              |  |..|||....|  ||    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-LVSTP-----CGSPCYASPECIS----GQNYNGLTSDVWSCGVVLFAMVTGQLP---WTKRNQS-----QLFEQ-------IRNGDYTIP-----NFLS
 ....      ||.| | .|. ..    ...|.  ..|.|| |.... |..|. |   | .. |      .|...       |..    .|     . .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

VQCASLISGLMTVDSEERLTVEQALHHQWL
 .| .||......| ..| . |. ..| |.
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 82762.m00198.AA Ciliate-E2-Unclassified 11-263 26 9.5e-68 231.39 In-house 1-352 (352) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-352/352
Sequence Identity: 26% (92 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLSS-----SSLEERFEEEIRINQQ------------------LHHPGVVGLIDIIKDETNYYVV
|..  .||.|.|. | .. |. || ||| |.  |..  .     ..  |   |....|..                  . || .| .... .|. | | |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFCPNGELFQFIVDR-----------------GRLSEAEAK-----PKIKMILDTVRYLHSLG-ISHRDLKPENILLDQYG---NPKVSDFGLSRFVG-
||.|..|.|.|.| .|                  ...| .||       .. ||.   |||. . | |||.||||||.|. |   ..|..|||.|.. . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PDNLVSTPCGSPCYA----SPECISGQNYNGLT---SDVWSCGVVLFAMVTGQLPWTKRNQSQ----------------LFEQIR
               .... .| ||.|.|     .||.. ||||.. .   .|.||.||.|..|..|..|   .|. |                |...| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NGDYTIPNFL--------SVQCASLIS----GLMTVDSEERLTVEQALHHQWL
.... .|.|         | ... .|.     .. .. ..|.| ||.| |.|.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 82762.m00198.AA TyrKc 11-263 25 9.6e-17 48.05 SMART 1-280 (280) Show / Hide
Range on Protein: 11-263
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YILRGVIGEGAFSHVVLAFHETQKTYYACKIVPKARLSSSSLEERFEEEIRINQQL--HHPGVVGLIDIIKDE-------TNYYVVMEFCPNGELFQFIV
  |  ..|||||  |...      .  | | . .        .| | .|.||  .|  ||| .| |. .. ..         ...|||..|.| | ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DRGR-LSEAEAKPKIKMILDTVRYLHSLGISHRDLKPENILLDQYGNPKVSDFGLSRFVGPD-------NLVST----PCG--SPC-YASPECISGQNYN
.... |. ..       | .  .|||| .. ||||   |.|..  .  |.|||||||... |          ..     .    |    .||||   ||.
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYG

--GLTSDVWSCGVVLFAMVT-GQLPWTK-----RNQSQLFEQIRNGDYTIPNFL-----SVQCASLISGLMT----VDSEERLTVEQALHHQWL
     ||||| ||... . | || |.        . ....|....|..  .        .| | . .  .|.     | |.| | ..   |. .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 82762.m00198.AA Pkinase_Tyr 11-224 26 1.5e-10 36.35 Pfam 1-232 (270) Show / Hide
Range on Protein: 11-224
Range on HMM: 1-232/270
Sequence Identity: 26% (62 aa)

YILRGVIGEGAFSHVVLAFHE----TQKTYYACKIVPKARLSSSS-LEERFEEEIRINQQL-HHPGVVGLIDIIK-DETN--YYVVMEFCPNGELFQFIV
 ..  ..||||| .|...        .|.  | |.. |   ...  . | | .|..|  || ||| .| |. ..  ..    .|.|||..|.| |  .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DR--GRLSEAEAKPKIKMILDT---VRYLHSLGISHRDLKPENILLDQYGNPKVSDFGLSRFV--GPDN-LVSTPCGSP-CYASPECISGQNYNGLTSDV
..  .. .      ...| ..      ||.| .. ||||   |.|..  .  |..||||.| .        ... .  |    .||||.   ..   |||
KHREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSDV

WSCGVVLFAMVT-GQLP-WTKRNQSQLFEQI-RNG
|| ||... ..| |. | .     ....|.| ..|
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG