Gene 97121.m00213 (T.vaginalis)

97121.m00213

Species: T.vaginalis
Alias: 97121.m00213, TvagK0132
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
97121.m00213.AA Protein None 393 None Fasta, JSON
97121.m00213.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 97121.m00213.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97121.m00213.AA AGC 14-267 24 8.49999999999e-113 292.48 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-395/395
Sequence Identity: 24% (98 aa)

YILRQRIGEGAFSSVWTADSK------KTNSTVAVKVISKKT-LEAPD--MFTRFKRE------------ISLLQQNN----------HPFIMH-FFEML
. .   ||.|.|. |. .  |       |.   |.||..||.     .  |  . ..|               |.. |          |||| .  .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDEKN--YYVIMEYAD--------NGDFETFLESK-M----TLPENMSRFFLAE-------MVLALDYLHNERRIAHRD-LKPQNILLDRYNNIRISDFG
.|...   | .|||.          |..|.||  . .    ...|...||..||       .||||.|||... | ||| ||| |||||.  .|...|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSNTFSDSN--------------------------------------------------PTMTSNCG--SPAFVAPEVVNGQPYNKSADIWS--LGVIFY
|.  . ...                                                   . .. ||  .| ..|||..    |.|..|.||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

RMVVGNLPFQGP----------DVKTILMKIV------SAEPYYP----------PSLSPDLRDLLQKMLCRNPEKRIT----------AKEIKAHPWI
 |..|  ||.|           . . .  ||       . .. .|          ...||...||..|.||..||||..          |.|||.||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
S_TKc 97121.m00213.AA S_TKc 14-267 34 8.99999999999e-105 355.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

YILRQRIGEGAFSSVWTADSKKTNSTVAVKVISKKTLEAPDMFTRFKREISLLQQNNHPFIMHFFEMLEDEKNYYVIMEYADN--GDFETFLESKMT---
| . . ||.|||..|. .  |||.  ||.|.|.           ...|||..|.. .||.| ..... .| ...|..|||.|.  ||  ...... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNIRISDFGLSNTFSDSNPTMTSNCGSPAFVAPEVVNGQPYNK-SADIWSLGVIFY
   .|| . ||.......||.|.|.  .| ||||||.|||||.  .| |.||||.  .       |. ||.| ..||||.   .|.| ..|.||.|.|.|
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

RMVVGNLPFQGPDVKTILMKIVSAEPYYPPSLSPDLRDLLQKMLCRNPEKRITAKEIKA-------HPWI
 |..|  ||.  ...... ||.          ||...|...|.|...||||.|| |. .       |||.
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 97121.m00213.AA CAMKL 14-267 34 8.49999999999e-104 332.14 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-297/297
Sequence Identity: 34% (103 aa)

YILRQRIGEGAFSSVWTADS-KKTNSTVAVKVISKKTLEA-------------PDMFTRFKREISLLQQNN---HPFIMHFFEMLEDEKN------YYVI
|.. . .|.|.|. |  |   . |.  ||.|.| || .               ...  | .|||..... |   || |....|..|....      .| .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYADNGD--FETFLESK----MTLPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLD-RYN-NIRISDFGLSNTFSD----SNPTMTSNCGSPA
|||...|.     .....      .||.  |..   .| |..|.|. . |.|||.|| ||||| . | || |.|||.|| . .    .. ...  ||||.
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

FVAPEVVNG--QPYN-KSADIWSLGVIFYRMVVGNLPFQGP-------DVKTILMKIVSAEPYYPP---SLSPDLRDLLQKMLCRNPEKRITAKEIKAHP
. |||...|  .||. . .||||.||| | ||.|.||| ..       | .  |....    ||||   ..| |.|||..||| .|||||.|...|. ||
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WI
| 
WM
Kinase 97121.m00213.AA CAMK 19-267 23 9.69999999999e-103 331.93 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-425/425
Sequence Identity: 23% (99 aa)

RIGEGAFSSVWTADSKKTN------------STVAVKVISKKTLE-------------------------APDMFTRFKREISLLQQ-------NNHPFI
 .|.|.|. |  .  |.|.              ||.|.|.|| |                           | .  ...|||.....        .|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

MHFFEMLED-------------------EKNYYVIM---EYADNG----D-FETFLESKM--------------TLPENMSRFFLAEMVLALDYLHNERR
 ...|. ||                   .|..| .|   ||...|    | |.   | .                ..|   |..   .. |..|.|.   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IAHRDLKPQNILLDRY-----------------NNIRISDFGLSNTFSDS-----------------------NPTMTSNCGSPAFVA-PEVVNG-----
|.|||||| |||||                   ||| |.|||..| | ..                       .. |.  ||.|...| |||.||     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QPYNKSADIWSLGVIFYRMVVGNLPFQGP-------------DVKTILMKIVSAEPYYPPS------------------------LSPDLR
         ..|....|.||.||| | |..| .||.|.             . . .. || ... ..||.                        .|.. .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLQKMLCRNPEKRITAKEIKAHPWI
||..|||...||||.|......|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 97121.m00213.AA Pkinase 14-267 30 1.2e-94 325.52 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YILRQRIGEGAFSSVWTADSKKTNSTVAVKVISKKTLEAPDMFTRFKR--EISLLQQNNHPFIMHFFEMLEDEKNYYVIMEYADNG----DFETFLE--S
| . ..||.|.|..|. .  |.|. .||||.|.|.  | ...  .  |  ||....  |||.|  .... ||....|..|||...|    |  ....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KMTL--PENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNI----RISDFGLSNTF-SDSNPTMTSNCGSPAFVAPEVVN-GQPYNKSADIW
. ..  .|.  .|.. ... .|.|.|. ..| ||||||.|||.|. ..|    .|.||||.  |   .|. ||. ||.| ..||||.. ||.| ...|.|
HGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVIFYRMVVGNLPFQGP------DVKTILMKIVSAEPYYPPSLS---------------------PDLRDLLQKMLCRNPEKRITAKEIKAHPWI
|.|.|.| |. |..||.|       | . .. .| .... .. . .                     ....|.. ..||..|.||.||..|. |||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 97121.m00213.AA AMPK 14-267 39 1.1e-92 275.44 In-house 1-254 (254) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-254/254
Sequence Identity: 39% (100 aa)

YILRQRIGEGAFSSVWTADSKKTNSTVAVKVISKKTLEAPDMFTRFKREISLLQQNNHPFIMHFFEML-EDEKNYYVIMEYADNGDFETFLESKMTLPEN
||. . ||||.|  |  .  . |.  ||.|.. |. .   ||  | .|||..|.  .|| |   .| . | ..  ...|||. .|.   .  ..  |.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

MSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNIRISDFGLSNTFSDSNPTMTSNCGSPAFVAPEVVNGQPYN-KSADIWSLGVIFYRMVVGNL
 .. |.. .. ...|.|.   |.|||||| |.|||  .|| | ||||||. .| .   |. ||||   |||.. |..|.    |||| ||| | |. | |
EACRFFQQIISGVEYCHRH-MIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTA-CGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFQGPDVKTILMKIVSAEPYYPPSLSPDLRDLLQKMLCRNPEKRITAKEIKAHPWI
||  ... |   ||.. |.| |  |||. .||...||. .|.|||| ..|..||| 
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 97121.m00213.AA MARK 14-267 35 4.1e-87 284.81 In-house 1-262 (262) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-262/262
Sequence Identity: 35% (95 aa)

YILRQRIGEGAFSSVWTADSKKTNSTVAVKVISKKTLEAPDMFTRFKREISLLQQNNHPFIMHFFEMLE--DEKN-YYVIMEYADNGDFETFLESK--MT
| . . ||.|... |  | .|.|.  ||.|.. |. |  |  .  ..|||..... .|| |  .|.. |  .|..  |.||||| .|.   .....    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYN--NIRISDFGLSNTFSDSNPTMTSNCGSPAFVAPEVVNGQPYN-KSADIWSLGVIFYR
|.|.  | .   .| |. |.|. . |.|||.||.|||.|  .  || |.|||.|. .  ..   .. ||.|.. |||.....||. . .|||||||. | 
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIP-PGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

MVVGNLPFQGPD--VKTILMKIVSAEPYYPPSLSPDLRDLLQKMLCRNPEKRITAKEIKAHPWI
||.|..|| | .   |..  ||.. .. .|. .|...|.|.|..|  |||.|.|..||  |||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 97121.m00213.AA Ciliate-E2 14-267 25 4.2e-84 285.7 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

YILRQRIGEGAFSSVWTADSKKT-----------------------NSTVAVKVISKKTLEAPDMFTRFKREIS----------LLQQNNHPFIMHFFEM
|.. . ||.|.|.||. .  .|.                       .. .|.|...|. .|.  .  .  |||           .|.|.|||.|. ..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--DEKNYYVIMEYADNGDFETFLESK-------------------MTLPENMSR-------FFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNI
 .  |..|.| .|||.. || . .....                    .. .   .       |..|...||| |||.. .| |||.||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RISDFGLSNTFSDSNP-------------------------------TMTSNCGSPAFVAPEVVNGQP---------YNKSADIWSLGVIFYRMVVGNLP
 |.|||||  ..|.|                                .  . ||.| ..|||..||..         |....||||||||.|.|. |..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FQGPDVKTILMKIVSAEPYYPP-------------------SLSPDLRDLLQK----MLCRNPEKRIT-AKEIKAHPWI
|         ...    ..  |                   ..|..  ||..|    ||...|||||| ...|. |||.
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 97121.m00213.AA Ciliate-E2-Unclassified 14-267 25 1.4e-83 283.98 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-352/352
Sequence Identity: 25% (89 aa)

YILRQRIGEGAFSSVWTADSKKTNSTV-----AVKVISKKTLEAPDMFTRFKREISLLQQNN-------------------HPFIMHFFEMLEDEKNYYV
|.. . ||.|.|..|. .  ||..  .     . |....| .    .  ....|.  .....                   ||||...|.. .|..| | 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEYADNGDFETFLESKMT-----------------LPENMSR-----FFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYN---NIRISDFGLSNTFS
.|||...|| . .......                 ..|. ..     |..|. ...|.||| .  | |||.||.|||.|  .   .|.|.|||.|    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

DS---------------NPTMTSNCGSPAFV----APEVVNGQPYN----KSADIWSLGVIFYRMVVGNLPFQGPDVKT----------------ILMKI
..               .  |...||.| .     ||||  || |.    ...||||||||.| |. |..||.... .                 .. .|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

VSAEPYYPP--------SLSPDLRDLLQ----KMLCRNPEKRITAKEIKAHPWI
   ....|.         .||   |...    |||  ||.||||...|. |||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 97121.m00213.AA ULK 14-267 26 3.5e-78 266.04 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YILRQRIGEGAFS-SVWTADSKKT---NSTVAVKVISKKTLEA-PDM------FTRFKREISLLQQNN---HPF--IMHFFEMLEDE--KNYYVIMEYAD
|.|....|.|.|   |  .  |||   |  ||.|.|.|| .   . .         .|.||..... .   ||.  |  .....|.   .|.| |||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDFETFLESKMT---------LPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNN------------IRISDFGLSNTFSD--SNPTMT-
 ||.|.... . .         |.|.  . |.   . .. .|| .. | |||.||||||.   .             . |.|||.. .. .   . .|. 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SNC------GSPAFVAPEVVN----GQPYN-KSADIWSLGVIFYRMVVGNLPFQGPDVKTIL----------------MKIVSAEPY---YPPSLSPDLR
. .      |.| . ||....    ..||. . .||||||.||| |. |  ||...   .                  .|    ...   . | .||...
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLLQKMLCRNPEKRITAKEIKAHPWI
||...||......||.  || .|||.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 97121.m00213.AA RSK 16-267 33 1.1e-77 264.35 In-house 1-278 (278) Show / Hide 
Range on Protein: 16-267
Range on HMM: 1-278/278
Sequence Identity: 33% (93 aa)

LRQR--IGEGAFSSVWTADSKKTNSTVAVKVISKKTLEAPDMFTRFKR-EISLLQQNN-HPFIMHFFEMLEDEKNYYVIMEYADNGDFETFLESKMT---
|..   .| |... .     ..|.   |.||..|... . .  || .. |.. |.  . |||| . ..  ..|.  | ||||   |.. | |. . .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDR---YNNIRISDFGLSNTF-SDSNPTMTSNCGSPAFVAPEVVN---GQP-YNKSADIWSLG
. |.  .| .|| |||...||    | |||||| |||.|       |...|||..  |  | |  . . |.. ...|||...   .|  ..|..|.||||
FSEDEACFYMAEIVLAVEHLHQQG-IIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VIFYRMVVGNLPFQG---PDVKTILMKIVSAE--PYYP--PSLSPDLRDLLQKMLCRNPEKRIT-----AKEIKAHPWI
|. | | .|..||||    . | |. .| ...  .  |  ..||.. .||..|||.|.|.||..     |.|||.|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 97121.m00213.AA ULK 14-267 26 1.8e-77 263.7 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-329/329
Sequence Identity: 26% (87 aa)

YILRQRIGEGAFSSVWTADSKKT----NSTVAVKVISKKTLEAPD-------MFTRFKREISLLQQNN--------HPFIMHFFEMLEDE--KNYYVIME
|.|....|.|.|  |  .  |||    |  ||.|.|.|...           |   .|.|| .... .        || |  .....|.   .|.| |||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADNGDFETFLESKMTLPENM----------SRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNN------------IRISDFGLSNTFSDS---N
| . ||.|.... . .|||.            . |.   . .. .|| ...| |||.||||||..  .             . |.|||.. .....   .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

PTMTSNC------GSPAFVAPEVVN----GQPYN-KSADIWSLGVIFYRMVVGNLPFQGPDVKTIL-MKIVSAEPYYPPS-------------------L
  |..        |.| . ||....    ..||. . .||||||.||| |..|  ||...   .   ..| .   ..||.                   .
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SPDLRDLLQKMLCRNPEKRITAKEIKAHPWI
||...||...||......||.  |. .|||.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 97121.m00213.AA Pkinase_Tyr 14-201 26 4.3e-16 55.14 Pfam 1-202 (270) Show / Hide 
Range on Protein: 14-201
Range on HMM: 1-202/270
Sequence Identity: 26% (54 aa)

YILRQRIGEGAFSSVWTADSK----KTNSTVAVKVISKKTLEAPD-MFTRFKREISLLQQN-NHPFIMHFFEMLE-DEKN--YYVIMEYADNGDFETFLE
 .. . .||||| .|. .  |    .|. .||||.. | .   .. .   | ||.... |  .|| |  .      ...   .|..|||. .||  ..| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----KMTLPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNIRISDFGLSNTF-SDSNP-TMTSNCGSPAF-VAPEVVNGQPYNKSADIW
.    |  |.  .   . ..   ...||. .... ||||   |.|... | ..|.||||. .  .|..  ......  | .  |||. |   ..   |.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLE-SKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGV
| ||
SFGV
Kinase 97121.m00213.AA TyrKc 14-267 21 2.3e-15 25.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YILRQRIGEGAFSSVWTADSKKTNSTVAVKVISKKTLEAPDMFTRFKREISLLQQN--NHPFIMHFFEMLEDE-------KNYYVIMEYADNGDFETFL-
  | . .|||||  |. .  |    .||||.. . .         | ||.... .   .|| |  ..    ..       . ....|||...||   .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ESKMTLPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNIRISDFGLSNTFSDS------NPTMTS----NCG--SPAF-VAPEVVNGQPY
... .|.      |        .|||   .. ||||   |.|... . ..|||||||    |         . ..    ..    |    |||. |   .
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

NKSADIWSLGVIFYRMV-VGNLPFQG-----PDVKTILMKIVSAEPYYPPSL---------SPDLRDLLQKMLCRNPEKRITAKEIKAHPWI
.   |.|| ||  . .   |  |  |      . . .. .. . .   .|           .... .. ..   ..||.| | .||  |  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF