Gene 92477.m00243 (T.vaginalis)

92477.m00243

Species: T.vaginalis
Alias: TvagK0799, 92477.m00243
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: LKB

Sequence

Name Sequence Type Origin Length Description Download
92477.m00243.AA Protein None 345 None Fasta, JSON
92477.m00243.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of 92477.m00243.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 92477.m00243.AA S_TKc 28-287 26 1.9e-82 281.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

YKELCLVGEGSFSKVFLGLDVNTNKYYAIKRINLKTFVRSSMGIHQLEREIEIMRQIKNKYVVQLHEVIHVPERDVVYLIVDYANC--GNLDQLIKSKVK
|. | ..|.|.|.||... ...|....|||.|.            ...|||.|... . ...|.|..|..    | .|.. .|..   |.| ..||.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

------LKPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSDGTILISDFGIGRSFQSAATVVGTPAYQSPEVVDDDCEYDEEEEIDPCKEDVWSL
      . . ... ...||.... ..|.|.|.| ||||.|||| .  .| |.|||. | .    |..||| | .|||.            ..|| |.||.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL----------GYGKCKCDWWSC

GVTLYQLAFNKLPFTGNNVFEIVRSIESSVLNKPEGADDVLWDLILHMLVVHPSRRYSIFDVIN-------HPYT
|..|| ..  . ||   ..... . |           .. ..|.| ..|.. |..|... .. .       ||. 
GCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92477.m00243.AA CAMK 33-287 22 1.4e-75 242.82 In-house 1-425 (425) Show / Hide 
Range on Protein: 33-287
Range on HMM: 1-425/425
Sequence Identity: 22% (94 aa)

LVGEGSFSKVFLGLDVNTN------------KYYAIKRINLKTFVR------------------------SSMGIHQLEREIEIMRQ-------IKNKYV
  |.|||.||.|. . ||.            . .||| |. |                            .    ....||||||..       .. . .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLHEVIHVPE-----------------RDVVYLIV---DYANCG----NLDQLIKSK---------------VKLKPQEICALFRQIAEGVMFLHQHNI
..|.||.  |.                 .. .|..    .|.  |     | . |...                ... .| . .||||...| ..|.|||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHQDLKPANILLKSD-----------------GTILISDFGIGRSFQS---------------------------AATVVGTPAYQS-PEVVDD--DCEY
|| |||| |||| ..                 ..| |.|||  . |..                             |..|||.| . |||.     |..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----DEEEEIDPCKEDVWSLGVTLYQLAFNKLPFTGN-------------NVFEIVRSIESSVLNKPEGADDV------------------------LWD
    |||.. .. | |.||.|| || .   ..|| |              |  |. . | .   . |.   .                           |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LILHMLVVHPSRRYSIFDVINHPYT
|| .||.| |..|..| .. |||  
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 92477.m00243.AA ULK 28-287 26 3.3e-67 229.58 In-house 1-324 (324) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-324/324
Sequence Identity: 26% (87 aa)

YKELCLVGEGSFS-KVFLGLDVNT---NKYYAIKRINLKTFVRSSMG------IHQLEREIEIMRQIK---NKY--VVQLHEVIHVPERDVVYLIVDYAN
|      |.|||  ||. | ...|   |.|.|.| |..| .  ..        . .|..||.||...|   ...  .|.|...   .  . .|.|..| |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

CGNLDQLIKSKVK---------LKPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSD------------GTILISDFGIGRSFQS-------AAT
.|.|.|.|| . |         |  ||.   |.||..| ..||.|||.| |.||.|||.. .            |.. |.||| ......         |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

VV------GTPAYQSPEVVDDDCEYDEEEEIDPCKEDVWSLGVTLYQLAFNKLPFTGNNVFEIV----RS----------IESSVLNKP-----EGADDV
 |      ||| | .|... .     |... .  | |.||||. .|.. ..| || ..   . .    .           |.   ...|         . 
CVNEKRIKGTPLYMAPQILQGQG---EQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

LWDLILHMLVVHPSRRYSIFDVINHPYT
. |||  ||.. .. | |. ...|||  
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 92477.m00243.AA ULK 28-287 25 2.6e-64 219.98 In-house 1-329 (329) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-329/329
Sequence Identity: 25% (86 aa)

YKELCLVGEGSFSKVFLGLDVNT----NKYYAIKRINLKTFVRSSMG------IHQLEREIEIMRQIK--------NKYVVQLHEVIHVPERDVVYLIVD
|      |.||| ||. | ...|    |...|.| | .... ...        . .|..||.||...|        ....|.|...   .  . .|.|..
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YANCGNLDQLIKSKVK----------LKPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSD------------GTILISDFGIGRSFQS------
| | |.|.|.|| . |          |  ||.   |.||..| ..||.|||.| |.||.|||.. .            |.. |.||| ......      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-AATVV------GTPAYQSPEVVDDDCEYDEEEEIDPCKEDVWSLGVTLYQLAFNKLPFTGNNVFEIV-----RS----------IESSVLNKP-----E
 . | |      ||| | .|... .     |... .  | |.||||. .|.. ..| || ..  .. .     .           |..  |. |      
MMMTCVNEKRLCGTPLYMAPQILQGQG---EQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

GADDVLWDLILHMLVVHPSRRYSIFDVINHPYT
   . . |||  ||.. .. | |. ...|||  
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 92477.m00243.AA AGC 28-287 17 6.2e-63 160.56 In-house 1-395 (395) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-395/395
Sequence Identity: 17% (73 aa)

YKELCLVGEGSFSKVFLGLDV------NTNKYYAIKRINLKT-FVRSSM-GIHQLERE------------IEIMRQIK----------NKYVVQ-LHEVI
.. | ..|.|||.||.|  ..       |.||||.| .. |.  |.     ...  .|             .|. ...          . ..|. ||   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

HVPERDVVYLIVDYAN--------CGNLDQLIKSKV-----KLKPQEICALFRQ-------IAEGVMFLHQ-HNIVHQD-LKPANILLKSDGTILISDFG
. .... .|.. .|..        .| .. ..  .      ..  ....  . .       |. .. .||. ..|.| | ||| |||| .|| | ..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IGRSFQS------------------------------------------------------AATVVG--TPAYQSPEVVDDDCEYDEEEEIDPCKE-DVW
    . .                                                      . | .|  || | .||..               |. | |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-------------YGKACDWW

S--LGVTLYQLAFNKLPFTGNN----------VFEIVRSIE------SSVLNKP----------EGADDVLWDLILHMLVVHPSRRYS----------IF
|  ||. .|.. . . ||.|.|           .|.  .|.      .  .  |          .  .. ..||| ..|...|..|            . 
SFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAE

DVINHPYT
.. |||. 
EIKNHPWF
Kinase 92477.m00243.AA Pkinase 28-287 23 1.3e-59 209.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-293/293
Sequence Identity: 23% (72 aa)

YKELCLVGEGSFSKVFLGLDVNTNKYYAIKRINLKTFVRSSMGIHQLE-REIEIMRQIKNKYVVQLHEVIHVPERDVVYLIVDYANCG----NLDQLIK-
|. .  .|.|||..|... ...|.| .|.|.|...   .|.. .. .  .||.||. .. ...|.|... .   .| .|.. .|...|     |  .|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

-SKVKL--KPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSDGTI----LISDFGI-----GRSFQSAATVVGTPAYQSPEVVDDDCEYDEEEEI
 .. ..   ..|..  ..||..|. ..|...|.| ||||.|||....|.|     |.|||.       . . . |..||| | .|||. .. .|.     
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP----

DPCKEDVWSLGVTLYQLAFNKLPFTGN------NVFEIVRSIESSVLNKPEGAD---------------------DVLWDLILHMLVVHPSRRYSIFDVI
   | |.||.|..||.... ..|| |       .  .... | .  |  ..  .                     . . |.|  .| . |..|... .. 
---KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

NHPYT
.||. 
QHPWF
Kinase 92477.m00243.AA Ciliate-E2 28-287 21 4.9e-55 187.35 In-house 1-365 (365) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-365/365
Sequence Identity: 21% (81 aa)

YKELCLVGEGSFSKVFLGLDVNTNKYYAIKRINLKT-----------------FVRSSMGIHQLEREIEIMRQIK----------------NKYVVQLHE
|| . . |.|.|..|... . ...| .|||.|. .                   . .  .| |...|| |||.|.                ........|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VIHVPERDVVYLIVDYANCGNLDQLIKSK-----------VKLKPQEICALFRQIAE---------------GVMFLHQHN-IVHQDLKPANILLKSDGT
.     .. .||. .|.. |.| ..||..            ... .||. ...||..               .. .||. | |.| |.|| |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

ILISDFGIGR-----------------------------------SFQSAATVVGTPAYQSPEVVDDDCEY-DEEEEIDPCKEDVWSLGVTLYQLAFNKL
| |.|||. .                                   ... . |..||| |..||..    .. .....    | |.|||||.||.. |.|.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFTGNNVFEIVRSIE-SSVLNKPEGADD-----VLW-----------DLILH----MLVVHPSRRYS-IFDVINHPYT
||       .   ..    ...||  .|     . |           |||      ||.. |. |.. . ...|||. 
PF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 92477.m00243.AA Ciliate-E2-Unclassified 28-287 21 3.6e-50 172.2 In-house 1-352 (352) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-352/352
Sequence Identity: 21% (78 aa)

YKELCLVGEGSFSKVFLGLDVNTNKYYAIKRIN-LKTFVRSSM--GIHQLEREIEIMRQIKNKYVVQ------------------LHEVIHVPERDVVYL
|| .   |.|.|.||..  . ....|||.| ..  . . . ..   . .. .|...| ..|. |..                   .... .   .. .|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IVDYANCGNLDQLIKSK-----------------VKLKPQEIC-----ALFRQIAEGVMFLHQHN-IVHQDLKPANILLKSDG---TILISDFGIGR---
. .|.. |.| | ||..                  ..  |...      .|.|| .|  .||. | |.| |.|| |||....|    | |.|||| .   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------SFQSAATVVGTPAYQ----SPEVVDDDCEYDEEEEIDPCKEDVWSLGVTLYQLAFNKLPFTGNNVFE---------------IV
                ..| . |..||| |.    .||| .    ...       | |.||||| ||.. |...|| .||  .               ..
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

RSIE-SSVLNKPE--------GADDVLWDLIL----HMLVVHPSRRYSIFDVINHPYT
...     ...|.        . ..  .|.|      ||.. |. |... ...|||. 
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 92477.m00243.AA CAMKL 28-197 30 6.9e-48 150.82 In-house 1-205 (297) Show / Hide 
Range on Protein: 28-197
Range on HMM: 1-205/297
Sequence Identity: 30% (63 aa)

YKELCLVGEGSFSKVFLGLD-VNTNKYYAIKRINLKTFVRSSMGIHQ-----------LEREIEIMRQIK---NKYVVQLHEVIHVPER----DVVYLIV
|. .   |.|||.|| |...  .|.. .||| |. |                      ..|||.||....    . ...|.|||  ||     . .||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DYANCGN--LDQLIKSK----VKLKPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSDG--TILISDFGIG---RS-----FQSAATVVGTPAYQ
 |.  |.  | . |...     .... | . .|||| ..| ..|.|.||| |.|| |||| ..|  .| |.||| .   |       |   |  |.|.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEVV
.||..
APEIF
Kinase 92477.m00243.AA MARK 28-287 32 1.2e-44 143.93 In-house 1-262 (262) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-262/262
Sequence Identity: 32% (88 aa)

YKELCLVGEGSFSKVFLGLDVNTNKYYAIKRIN---LKTFVRSSMGIHQLEREIEIMRQIKNKYVVQLHEVIHVPERDV-VYLIVDYANCGNLDQLIKSK
|| |   |.||..|| |.....|.. .||| ..   |  .   ..    ..||||||.... .....|..||  ...   .||| .||  |.| . ||..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKN----VMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAH

--VKLKPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSDG--TILISDFGIGRSFQSAA---TVVGTPAYQSPEVVDDDCEYDEEEEIDPCKEDV
   .|.  |  ..|||| ..| ..|..|||| |.|| |||. ..|   | |.||| .. ...     |  |||.| .||..       . .. |  | |.
PNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIF-------LKKPYDGPKVDI

WSLGVTLYQLAFNKLPFTGNN--VFEIVRSIESSVLNKPEGADDVLWDLILHMLVVHPSRRYSIFDVINHPYT
||||| || .   ..|| | .    |. . | . .   |    . ...||  .|.| |..| .| .. .||  
WSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 92477.m00243.AA STE 28-287 21 3.2e-44 153.24 In-house 1-359 (359) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-359/359
Sequence Identity: 21% (79 aa)

YKELCLVGEGSFSKVFLGLDVN---------------TNKYYAIKRINLKTFVRSSMG--------------IHQLEREIEIMRQIK--NKYVVQLHEVI
.. .  .|.|.| .|.......               |....|||..||..   ..                . |...||.||.. .   ...|. .   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

HVP-----ERDVVYLIVDYANCGNLDQLIKSK-VKLKP-------------QEICALFRQIAEG-VMFLHQHNIVHQDLKPANILLKSDGTILISDFGIG
 .      ..| ....  | . | ||..||.|  ..||             ..|..  ||| .|   .||.|.|.| |.|||||||     . ..|||. 
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

RSFQS--------------------AATVVGTPAYQSPEVVDD-----DCEYDEEEEIDPCKEDVWSLGVTLYQLAFNKLPF-TGNNV---FEIVRSIES
 ....                      |.|||| . .|||..      | .||       .| |.|||| |.  .|  | |. ....    |.| ... .
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-------TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

SV---------LNKPEGAD----------------------DVLWDLILHMLVVHPSRRYSIFDVIN--HPYT
.           . |   |                      . . | | . |.  |. | .  . ..  ||  
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 92477.m00243.AA NEK 28-287 25 2.6e-43 150.23 In-house 1-286 (286) Show / Hide 
Range on Protein: 28-287
Range on HMM: 1-286/286
Sequence Identity: 25% (76 aa)

YKELCLVGEGSFSKVFLGLDVNTNKY-----YAIKRINLKTFVRSSMGIHQLE-REIEIMRQIKNKYVVQLHEVIHVPERDVVYLIVDYAN-CGNLDQL-
|...  .|.|||.||..  . ...|      |..|.||..    |.    ..   |. | .|.|. ..|  .. .   . .  . . .|..  |.|.|. 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGN--MSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKI

--IKSKV----KLKPQEICALFRQIAEGVMFLHQH-----NIVHQDLKPANILLKSDGT----ILISDFGIGRSFQ----SAAT-VVGTPAYQSPEVVDD
  || .      .   .|   | |.. .. ..|..     .|.| |.||.|| | ....    . | |||| . ..     | | .|||| | ||||.  
KSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQ-

DCEYDEEEEIDPCKEDVWSLGVTLYQLAFN--KLPFTGN--NVFEIVRSIESS-VLNK-PEG--ADDVLWDLILHMLVVHPSRRYSIFDVINHPYT
.  |..       | |.||||. ||...    | || ..  |  . .  |      .. |.     . | .||  || . |. |.|. .....|. 
NKPYNN-------KSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 92477.m00243.AA CAMKL 215-287 28 1.3e-15 46.1 In-house 218-297 (297) Show / Hide 
Range on Protein: 215-287
Range on HMM: 218-297/297
Sequence Identity: 28% (24 aa)

DVWSLGVTLYQLAFNKLPFT-------GNNVFEIVRSIESSVLNKPE---GADDVLWDLILHMLVVHPSRRYSIFDVINHPYT
|.||.||.|| . . .|||        |.. .   . .. .   .|      .  . ||| .||.| |..|..| .. |||  
DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 92477.m00243.AA TyrKc 28-279 19 5.1e-15 20.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-279
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

YKELCLVGEGSFSKVFLGLDVNTNKYYAIKRINLKTFVRSSMGIHQLEREIEIMRQI--KNKYVVQLHEVIHVPER-----DVVYLIVDYANCGNLDQLI
 . .   ||| | .|..|         |.| ..  .       .  . ||..||...  ... .|.|. |.  ..|     . ..... |.  |.|.. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KSKVK-LKPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSDGTILISDFGIGRSFQSA--------ATVV----GTP-----AYQSPEVVDDDCE
... . |.... .    |||.|  .||..|..| ||   |.|.....|. |||||  |   .           ..    |.         .||.  ....
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

YDEEEEIDPCKEDVWSLGVTLY-QLAFNKLPFTG-----NNVFEIVRSIESS-VLNKPEG--------ADDVLWDLILHMLVVHPSRR------YSIF
. .       | |||| ||...  . . . |  |      . .|... ...   . .|.         . | . ....      |. |      ...|
FTT-------KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 92477.m00243.AA Pkinase_Tyr 28-174 24 8.7e-15 50.7 Pfam 1-156 (270) Show / Hide 
Range on Protein: 28-174
Range on HMM: 1-156/270
Sequence Identity: 24% (39 aa)

YKELCLVGEGSFSKVFLGLDV----NTNKYYAIKRINLKTFVRSSMGIHQLEREIEIMRQI-KNKYVVQLHEVIHVPERD-VVYLIVDYANCGNLDQLIK
 . .   |||.| .|..|       ||.   |.| .   .   .   .  . ||..||.|. ... .|.|. |.   ..   .|... |. .|.|.   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----KVKLKPQEICALFRQIAEGVMFLHQHNIVHQDLKPANILLKSDGTILISDFG
.    | .|......   .|||.|  .|...|..| ||   |.|....... |.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 92477.m00243.AA Pkinase_Tyr 215-224 60 5.124829 0.68 Pfam 196-205 (270) Show / Hide 
Range on Protein: 215-224
Range on HMM: 196-205/270
Sequence Identity: 60% (6 aa)

DVWSLGVTLY
|||| ||...
DVWSFGVLMW