Gene 95378.m00074 (T.vaginalis)

95378.m00074

Species: T.vaginalis
Alias: TvagK0250, 95378.m00074
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
95378.m00074.AA Protein None 316 None Fasta, JSON
95378.m00074.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 95378.m00074.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 95378.m00074.AA S_TKc 14-264 25 4.8e-64 220.01 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-264
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

YKFIKQVGKGCFATCYLVFDTRYKKEFICKVCHSNSNNPESSNKQKFYQNEIDALINITHPNIIKIYNYFEDHNFLYIILEYCNQ--FSLDKFISMHGN-
|......||| |...|.. ... .... .|. .            .  ..||. | .  ||||.|.| .|.| ..||...|||..   .| ..|  .|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LKRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYNKIKLADFGFASYQEYDANEVRGSLAYIPPEKINLVKYDPFASDVWSFGVSVYYL
     .   .   .. | . .| .||  || | |.||.||||||   ||..|||.|       . . |.. |..|| .   .|.....|.||.|. .| .
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

AFGSLPFQGETKEELSQNIKKANYKMPDTSYDFVRDIVTHTLVIDPSKRWTMKQIVD---------YL
. |  ||.  . ... ..|.         | ..   .. . |. ||.||.|  ..           ..
LCGYPPFP--QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95378.m00074.AA CAMK 19-260 18 1.1e-58 187.46 In-house 1-419 (425) Show / Hide 
Range on Protein: 19-260
Range on HMM: 1-419/425
Sequence Identity: 18% (78 aa)

QVGKGCFATCYLVFDTRYK------------KEFICKV----------------CHSNSNNPE---------SSNKQKFYQNEIDALIN-------ITHP
. |.| |.. .|..... .            ... .|.                | .   . .         . ...|. ..||. . .       . ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNC-Y-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHP

NIIKIYNYFEDHNF-------------------LYIIL---EYCNQF----SLDKFISMHGN---------------LKRNQLYDFILQFATGLHHCHLY
||||.| ..||...                   .|...   |||        |  .|  ||.               ..  .   .. | . ..|.||  
NIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GIAHHDIKPANILLDEY-----------------NKIKLADFGFASYQEY--------------------------DANEVRGSLAYIP-PEKINL----
.|.| |.|| |||||.                  |.||..||||| . .                             ... |...|.. || .|     
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------VKYDPFASDVWSFGVSVYYLAFGSLPFQGE-------------TKEELSQNIKKANYKMPDTSYDF------------------------V
          .|.....|.|| ||  | .  | .||.|.             . .|| ..|.|..| .|.   .                         .
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

RDIVTHTLVIDPSKRWTMKQI
.| . . |. ||.||.| .|.
KDLIRKMLQVDPEKRMTIEQC
Pkinase 95378.m00074.AA Pkinase 14-264 24 6.3e-58 203.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-264
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

YKFIKQVGKGCFATCYLVFDTRYKKEFICKVCHSNSNNPESSNKQKFYQN----EIDALINITHPNIIKIYNYFEDHNFLYIILEYCNQF----SLDKFI
|......|.| |...|.  .  . |.. .|.      . .. ...| ...    ||  . .. ||||...| .|||.. .|...|||.      .|  .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKII-----KKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

S--MHGNL--KRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYNKI----KLADFGFAS---YQEYDANEVRGSLAYIPPEKINLVKYDPFASD
|  .||..    ... ....| . || .||  || | |.||.|||.|. . |    |..|||.|    |  . .. . |.. |..|| |.  .|.. ..|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVD

VWSFGVSVYYLAFGSLPFQGE------TKEELSQNIKKANYKMPDTSY---------------------DFVRDIVTHTLVIDPSKRWTMKQIVDY--L
.||.|. .|....| .||.|.      .. .. ..|... .. .                         .  .|...  |  ||.||.| .||.    .
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95378.m00074.AA CAMKL 14-261 27 3.9e-49 154.86 In-house 1-292 (297) Show / Hide 
Range on Protein: 14-261
Range on HMM: 1-292/297
Sequence Identity: 27% (81 aa)

YKFIKQVGKGCFATCYLVFDTRY-KKEFICKVCHSNSNNPESSNKQKFY----------QNEIDALINIT---HPNIIKIYNYFEDHNF------LYIIL
|...|. ||| |..  |  ..|. ...   |. . .  . .  .|...           . ||  .  .    ||||||.|  .|. ..      .|...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCNQFS--LDKFISMHGN----LKRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYN--KIKLADFGFASYQE------YD-ANEVRGSLAYI
|||   .  |  .|  ||.    .. ..   .  |   ....||  ||.| |||| |||||| .  .||..||||. ...       .  ..  ||..| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEKINL--VKYDPFASDVWSFGVSVYYLAFGSLPFQGET--------KEELSQNIKKANYKMPDTSYD-FVRDIVTHTLVIDPSKRWTMKQIV
.|| ..    .|| .. |.|| ||  | . .| ||| ..|        . .|   |..  |..|  ..   .||.  . |. .|.|| |..||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIM
Kinase 95378.m00074.AA Ciliate-E2 14-260 21 2.3e-46 157.13 In-house 1-359 (365) Show / Hide 
Range on Protein: 14-260
Range on HMM: 1-359/365
Sequence Identity: 21% (81 aa)

YKFIKQVGKGCFA-----TCYLV--------FDTRY----------KKEFICKVCHSNSNNPESSNKQKFYQ---------NEIDALINITHPNIIKIYN
|||||. |.|.|.     . ..|        .| ..          |. .. . . ....  . ..... ..         ||   | .. ||||||.| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YFE--DHNFLYIILEYCNQFSLDKFIS------------MHGNLKRNQLYDFILQFAT---------------GLHHCHLYG-IAHHDIKPANILLDEYN
.|.  | | .|...|||.. .| ..|               .... ..  ... | .                .|...|  . | | |||| |||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

KIKLADFGFASYQEYD----------------------------------ANEVRGSLAYIPPEKINLVKYDP--------FASDVWSFGVSVYYLAFGS
 ||..|||.. ..  |                                  .| . |.. | .|| .|  |||         ...|.||.||  |.. || 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFQGETKEELSQNIKKANYKMPDT--------------SY----DFVRDIVTH----TLVIDPSKRWT-MKQI
.||         |.||. ... |                |.    . . |.        |. ||.|| | ..||
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase 95378.m00074.AA Ciliate-E2-Unclassified 14-260 22 9.9e-45 153.08 In-house 1-346 (352) Show / Hide 
Range on Protein: 14-260
Range on HMM: 1-346/352
Sequence Identity: 22% (79 aa)

YKFIKQVGKGCFATCYLVFDTRYKKEF-----ICKVCHSNSNNP-----------ESSNKQKFYQNEID-------ALINITHPNIIKIYNYFEDHNFLY
||.||| |.|.|.. |.. .   | ..     ..|. . ....            |  ||.| |...          |.|. ||.|.| . .|.| . .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQR-KYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

IILEYCNQFSLDKFISMHGN-----------------LKRNQLY-----DFILQFATGLHHCHLYG-IAHHDIKPANILLDEYN---KIKLADFGFASYQ
|..|||.. .| ..|.  ..                 .  .|       ... |   || ..|  . | | |||| |||.|. .   .||..|||.....
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

EYD------------------ANEVRGSLAYI----PPEKINLVKYDP---FASDVWSFGVSVYYLAFGSLPFQGETKEE---------------LSQNI
...                  .. . |.. |.    .|| .   .||    ...|.||.||  |.. || .||.....|.                 ...
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

KKAN-------------YKMPDTSYDFVRDIVTHTLVIDPSKRWTMKQI
.|..             .. ...  ||..|.    |. .|.|| |..||
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Kinase 95378.m00074.AA MARK 14-261 30 3.1e-44 142.59 In-house 1-257 (262) Show / Hide 
Range on Protein: 14-261
Range on HMM: 1-257/262
Sequence Identity: 30% (78 aa)

YKFIKQVGKGCFATCYLVFDTRYKKEFICKVCH-SNSNNPESSNKQKFYQNEIDALINITHPNIIKIYNYFE--DHNF-LYIILEYCNQFSLDKFISMH-
||..|. |.| .|. .|. ........  |.    . | |   .. |  . ||. .  . |||||| . ..|  . .  .|.|.||.   .|  .|  | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDP---QWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHP

-GNLKRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYN--KIKLADFGFASYQEYDA--NEVRGSLAYIPPEKINLVKYDPFASDVWSFGVSVY
 | |. .  . .  |   ... ||  .|.| |||| |||.|| .  .||..||||.   . .   |.  |...| .|| ..  .|| .. |.|| ||  |
NGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY

YLAFGSLPFQGET--KEELSQNIKKANYKMPDTSYDFVRDIVTHTLVIDPSKRWTMKQIV
..  |..|| | |   .|| ..| . .|. |.   .  |...   |...|..| |...|.
FMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIM
Kinase 95378.m00074.AA ULK 14-260 21 1.5e-42 146.39 In-house 1-323 (329) Show / Hide 
Range on Protein: 14-260
Range on HMM: 1-323/329
Sequence Identity: 21% (71 aa)

YKFIKQVGKGCFATCYLVFDTRYK----KEFICKVCHSNSNNPESSNKQ-----KFYQNEIDALINIT--------HPNIIKIYNYFEDH--NFLYIILE
|  ... ||| |.. |  .. . |    . ..||.  ... | .. . .     .. .|||. .  .         ||||.| | .||.   | .|||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCNQFSLDKFIS----------MHGNLKRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYNK------------IKLADFGFASYQEYD-----
|||.  |...|.           ...|  ..   |. |.. |. . |  .| | ||||.|||... .             .|.||||||   ..|     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ANEVR------GSLAYIPPEKIN----LVKYDPFASDVWSFGVSVYYLAFGSLPFQGETKEELSQNIKKANYKMPDTSY--------------------
 .          |.  |  |. ..      .|. . .|.||.|.  |.. .|  ||..  ....  .|.. ... |....                    
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

DFVRDIVTHTLVIDPSKRWTMKQI
. ..|.    |..|...| .  ..
PECKDLIRRMLQYDEKDRISWEEL
Kinase 95378.m00074.AA ULK 14-260 22 1.9e-42 147.34 In-house 1-318 (324) Show / Hide 
Range on Protein: 14-260
Range on HMM: 1-318/324
Sequence Identity: 22% (73 aa)

YKFIKQVGKGCFA-TCYLVFDTRY---KKEFICKVCHSNSNNPESSNKQ-----KFYQNEIDALINIT---HPN--IIKIYNYFEDH--NFLYIILEYCN
|  ... ||| |. . |  .. .    .. . ||.   .. |  ... .     .. .|||  .  .    |||  |.| | .||.   |..|||.||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

QFSLDKFIS---------MHGNLKRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYNK------------IKLADFGFASY-QEY-DANEVR--
.  |...|           ...|  ..   |. |.. |. . |  .| | ||||.|||. . .             .|.||||||   ...  .  ..  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSLAYIPPEKIN----LVKYDPFASDVWSFGVSVYYLAFGSLP----FQGET--KEELSQN-------IKKANYKMPD-----TSYDFVRDI
        |.  |  |. ..      .|. . .|.||.|.  |.. .|. |    |. .   ...| .|       ||. . . |.        . ..|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VTHTLVIDPSKRWTMKQI
    |..|...| .  .|
IRRMLQYDEKDRISWEEI
Kinase 95378.m00074.AA CAMK-Unique 14-262 21 1.9e-41 134.45 In-house 1-359 (363) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-359/363
Sequence Identity: 21% (78 aa)

YKFIKQVGKGCFATCYLVFDTRYKKEFICKVCHSNSNNPESSNKQKF------------------YQNEIDALINITHPNIIKIYNY----FEDHN----
||... .|.| |   | ..|   .|.. ||.     .   ...|||                   . .|.. ..   ||||||.| .    |.| .    
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVK---KQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLC

-----------FLYIILEYCNQFSLDKFISM--------------------HGNLKR--NQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEY----
            .||..|||.   | . |                       | .    ..    ... .  . . |  .| | |.|. ||.. .     
DLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDN

------------NKIKLADFGFASYQEYDANEVR-------GSLAYIPP--------------EKINLVKYD-PF--ASDVWSFGVSVYYLAFGSLPFQG
            ..|||.||| .   .|. |...       |.. |. |              | || ..|| .   ||| || ||  ||...|..|| .
NHHRDFPYDWSNWHIKLCDFGLC--CHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDC

ETKE--------ELSQNIKKANY-KMPDTSYDF-------VRDIVTHTLVIDPSKRWTMKQIVD
|...        |. ..|.|..| . .   ..          |.|. ....||..||. |.. .
ECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLE
Kinase 95378.m00074.AA GIN4 71-269 35 1e-40 127.53 In-house 91-293 (293) Show / Hide 
Range on Protein: 71-269
Range on HMM: 91-293/293
Sequence Identity: 35% (74 aa)

ITHPNIIKIYNYFEDHNFLYIILEYCNQFSLDKFISMHGNLKRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYNK-IKLADFGFASYQEYDA-
| |||....|. .| .| ||..||| ..  |  ..  || |       .  |   |.  || ..| | |.|| |.|||. .. ||.|||| |  .     
ISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDNKL

-NEVRGSLAYIPPEKINLVKYDPFASDVWSFGVSVYYLAFGSLPFQGE--TKEELSQNIKKANYKMPDT---SYDFVRDIVTHTLVIDPSKRWTMKQIVD
 .   ||  |  || .  . |. ||||||| || .. |  | |||. |     .|   ..| .|.||.    | .  .|..   ||.|| || ....|  
LETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISRE-AQDLIRKILVVDPEKRIKTRDI--

YLKDQQI
 ||   |
-LKHPLI
Kinase 95378.m00074.AA PLK1 14-264 30 8.1e-40 128.4 In-house 1-253 (253) Show / Hide 
Range on Protein: 14-264
Range on HMM: 1-253/253
Sequence Identity: 30% (77 aa)

YKFIKQVGKGCFATCYLVFDTRYKKEFICKVCHSNSNNPESSNKQKFYQNEIDALINITHPNIIKIYNYFEDHNFLYIILEYCNQFSLDKFISMHGNLKR
|.  . .||| || || . |.  |. |  ||  . |    .  ..|  | ||.   .. |..|.|....|||....||.|| |.. ||       . .  
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVV-PKSLLIKQHQRDKMTQ-EIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITE

NQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYNKIKLADFGFASYQEYD---ANEVRGSLAYIPPEKINLVKYDPFASDVWSFGVSVYYLAFGSL
     .. | . | .. |   | | |.|  |. |..  ..|. ||| |   |||        |   || || .|      |  |.|| |  .| | ||. 
PECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHS-FEVDIWSIGCIMYILLFGQP

PFQGETKEELSQNIKKANYKMPDTSYDFVRDIVTHTLVIDPSKRWTMKQIV--DYL
||  .. .|  . |||..|..|.      .... . |  ||..| |..|..  ...
PFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 95378.m00074.AA TyrKc 14-264 21 1.3e-14 13.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-264
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YKFIKQVGKGCFATCYLVFDTRYKKEFICKVCHSNSNNPESSNKQKFYQNEIDALINI--THPNIIKIYNYFEDH-------NFLYIILEYCNQFSLDKF
 ...|. | |.| . |.   .    .   |......       .. |.. |.  . ..   ||||...| .  ..         |.|..||.   .|...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMR-EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

ISMHGN-LKRNQLYDFILQFATGLHHCHLYGIAHHDIKPANILLDEYNKIKLADFGFASYQ-----------EYDANE---VR--GSLAYIPPEKINLVK
.  |.. |.  .| .| .| | |  . |  .. | |.   |.|..| . .| .||| . .             |.. |    .    .   .|| ||  |
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDPFASDVWSFGVSVY-YLAFGSLPFQG-----ETKEELSQNIKKANY-KMPDT--------SYDFVRDIVTHTLVIDPSKRWTMKQIVDYL
.  ..||||||||  .  . .|  |  |      . .|. ...|. .. . |.           | . .| .     ||..| |...|....
FT-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 95378.m00074.AA Pkinase_Tyr 54-264 25 4.4e-11 38.16 Pfam 42-270 (270) Show / Hide 
Range on Protein: 54-264
Range on HMM: 42-270/270
Sequence Identity: 25% (60 aa)

SSN--KQKFYQNEIDALINI-THPNIIKIYNYFE-DHNF--LYIILEYCNQFSLDKFISMH----GNLKRNQLYDFILQFATGLHHCHLYGIAHHDIKPA
...  ...| . |.  . ..  ||||.. |     .     .||..||.   .|...   |    ..|.  .| .. .| | |. . .  .. | |.   
HEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAAR

NILLDEYNKIKLADFGFASYQEYDANE-VRGS-----LAYIPPEKINLVKYDPFASDVWSFGVSVYYLAF-GSLP-FQGETKEELSQNIKKANYKM--PD
|.|..| |..| .||| | . . | .  . ..         .|| ||  |.   .||||||||  . .   |  | ..| . ||. . |.. .| |  |.
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPE

TSYDFVRDIVTHTLVIDPSKRWTMKQIVDYL
   | . |. ..    ||..| |...|.  |
NCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL